Clinical trials: Survival , Tumor
Testicular Cancer, Survivorship
Late Subclinical Cardiovascular Disease in Testicular Cancer Survivors
Late subclinical cardiovascular disease in testicular cancer survivors exposed to cisplatin-based chemotherapy and bone marrow transplant
- Conditions
- Testicular Cancer, Survivorship, ASCVD, Coronary Artery Disease
- Trial name
- NCT05611307
- Testing
- Lipid profile, Coronary artery assessment, Hormone levels for hypogonadism
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Indiana University
Ovarian Cancer
Study of the Impact on Survival of a Paradigm Shift in the Therapeutic Strategy of Patients With Advanced Ovarian Cancer
Ovarian cancer is the 8th leading cause of cancer-related death in women. Its prognosis is poor, with diagnosis often made at an advanced stage.
- Trial name
- PACO (NCT06907771)
- Where
- France
- Volunteers
- 130 people
- Sponsor
- University Hospital, Strasbourg, France
Breast Neoplasm Female, Quality of Life
PRO Survivorship Concerns ITA
Breast cancer survivors typically experience fatigue, pain, insomnia, depression, anxiety, difficulty in concentrating, memory impairment, body image problems, vaginal dryness, interest in sex decreasing, hot flashes, gain…
- Conditions
- Breast Neoplasm Female, Quality of Life, Psychological Distress
- Trial name
- PRO (NCT06080607)
- Testing
- Patient Reported Outcome (PRO)
- Where
- 2 sites in Italy
- Volunteers
- 280 people
- Sponsor
- Regina Elena Cancer Institute
Cancer Survivors
Cancer Survivorship in Hematologic Malignancies
General objective: to improve care for haematological cancer survivors. This study will (i) Estimate the incidence of cancer survivor syndrome (CSS) in adult Egyptian patients with haematological neoplasms (HN).
- Trial name
- NCT05780411
- Testing
- questionnaire
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Assiut University
Carcinoma, Non-Small-Cell Lung
Progression Free Survival (PFS) Using Erlotinib for Non-Small-Cell Lung Cancer (NSCLC) in Chinese Population
This trial is an extension to ENSURE, a study of erlotinib versus gemcitabine/cisplatin combination chemotherapy as the first-line treatment for patients with non-small-cell lung cancer (NSCLC) with mutations in the tyrosine…
- Trial name
- NCT02000531
- Testing
- Erlotinib, Chemotherapy
- Where
- 11 sites in China
- Volunteers
- 45 people
- Sponsor
- Hoffmann-La Roche
Gastric Cancer, Gastric Adenocarcinoma
Evaluation of Intra-operative Photographs for the Assessment of a Proper Lymphadenectomy in Minimally-invasive Gastrectomies for Gastric Cancer (PhotoNodes)
Even after the wide introduction of chemo/radiotherapy in the treatment algorithm, adequate surgery remains the cornerstone of gastric cancer treatment with curative intent.
- Conditions
- Gastric Cancer, Gastric Adenocarcinoma, Lymphadenectomy, Minimally Invasive Surgery
- Trial name
- PhotoNodes (NCT06466902)
- Testing
- Quality assessment of D2 lymphadenectomy using the PhotoNode Score
- Where
- 8 sites in Italy
- Volunteers
- 326 people
- Sponsor
- Azienda Ospedaliero-Universitaria di Parma
Oral Cancer
The Optimal Neck Treatments Strategy of Early Oral Cancer Based on Adverse Pathological Factor
Cervical nodal metastasis is the most certain prognostic factor in oral cancer. Appropriate management of the neck is therefore of paramount importance in the treatment of oral cancer.
- Trial name
- NCT03017053
- Testing
- Radiotherapy, Elective neck dissection
- Where
- China
- Volunteers
- 270 people
- Sponsor
- Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
Gastric Cancer
Epirubicin Cisplatin and Fluorouracil (FU) Combined With Endostar in Patients With Advanced or Metastatic Gastric Cancer
The purpose of this study is to evaluate the efficacy and tolerability of the ECF regimen (epirubicin, cisplatin and FU) combined with endostar-- a inhibitor of angiogenesis, in patients with advanced or metastatic gastric cancer…
- Trial name
- NCT00595972
- Testing
- ECF-endostar
- Where
- China
- Volunteers
- 25 people
- Sponsor
- Fudan University
Colorectal Cancer
Studying DNA and Outcome in Patients With Advanced Colorectal Cancer Treated With Fluorouracil and Oxaliplatin With or Without Bevacizumab on Clinial Trial E-3200
RATIONALE: Studying samples of blood, urine, and tissue from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer.
- Trial name
- NCT00897819
- Testing
- DNA methylation analysis, loss of heterozygosity analysis, microsatellite instability analysis
- Volunteers
- 350 people
- Sponsor
- ECOG-ACRIN Cancer Research Group
Recurrence Free Survival, Bladder Cancer Recurrence
CRUCIAL-R Study : Cruciferous Vegetables Dietary Regimen in NMIBC
Emerging evidence highlights the importance of nutrition in modulating cancer-related pathways, suggesting that specific dietary patterns and food choices may influence cancer risk.
- Trial name
- CRUCIAL-R (NCT07391137)
- Testing
- Cruciferae intake diet, Habituary dietary regimen
- Where
- Italy
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- S. Andrea Hospital
Prostate Cancer
Enhancing Survivorship Care Planning for Patients With Localized Prostate Cancer Using A Couple-focused Web-based Tailored Symptom Self-management Program
The purpose of this research study is to examine the feasibility of the enhanced survivorship care plans (ESCPs, regular SCPs with the a web-based couple-focused symptom self-management project (PERC) or National Cancer Institute…
- Trial name
- SCP (NCT04350788)
- Testing
- Survivorship Care Plan, Enhanced Survivorship Care Plan
- Where
- United States
- Volunteers
- 124 people
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Metastatic Colorectal Cancer
An Observational Study of Bevacizumab in Chinese Patients With Metastatic Colorectal Cancer
This observational, multicenter, prospective study will evaluate the use of bevacizumab in real clinical practice in chinese patients with metastatic colorectal cancer.
- Trial name
- NCT01860144
- Testing
- Bevacizumab
- Where
- China
- Volunteers
- 250 people
- Sponsor
- Peking University
Neuroendocrine Tumors
PFS and OS of Patients With Advanced Neuroendocrine Cancer (NEN) After Systemic Treatment
This is a retrospective study. The analysis includes patients with advanced neuroendocrine cancer (NEN) treated with systemic therapy, because of inoperable primary tumor or/and metastasis, clinical, imaging, biochemical disease…
- Trial name
- NCT04331912
- Where
- 2 sites in Poland
- Volunteers
- 100 people
- Sponsor
- University of Warmia and Mazury
Hematologic Malignancy, Hematopoietic Stem Cell Transplant
A Study of the Effect of Laughter Therapy on the Mental Health and Quality of Survival of Hematopoietic Stem Cell Transplant Patients
主要研究目的: 1)探讨笑疗法在造血干细胞移植患者移植心理健康及生存质量中的效果。 次要研究目的: 1. 了解造血干细胞移植患者移植后3个月、6个月、1年内的心理健康变化和生存质量水平; 2. 探讨笑疗法在造血干细胞移植患者预后等结局指标中的应用效果。
- Trial name
- NCT06792630
- Testing
- laughter therapy intervention
- Volunteers
- 98 people
- Sponsor
- Institute of Hematology & Blood Diseases Hospital, China
Uterine Cervical Neoplasm, Laparotomy
Different Surgical Approaches in Patients of Early-stage Cervical Cancer
This multi-center, randomized controlled study aims to compare the survival outcomes (including overall survival, progression-free survival and disease-free survival between Chinese uterine cervical patients receiving different…
- Conditions
- Uterine Cervical Neoplasm, Laparotomy, Laparoscopy, Survival
- Trial name
- NCT03739944
- Testing
- Laparotomic radical hysterectomy, Laparotomic radical trachelectomy, Laparoscopic radical hysterectomy
- Where
- China
- Volunteers
- 700 people
- Sponsor
- Lei Li
Patient Outcome Assessment, Morbidity
Outcomes of Surgical Resection After Induction Treatment in Non-Small Cell Lung Cancer (SRaIT)
Surgery still remains the main treatment option for Non-Small Cell Lung Cancer (NSCLC) which is limited within the lung parenchyma and possibly invades the intrapulmonary or hilar nodes.
- Conditions
- Patient Outcome Assessment, Morbidity, Mortality
- Trial name
- SRaIT (NCT04092465)
- Testing
- Pulmonary parenchyma resection, lobectomy, pneumonectomy, sleeve lobectomy, extended lobectomy/pneumonectomy
- Volunteers
- 42 people
- Sponsor
- AHEPA University Hospital
Colorectal Cancer, Surgery
Survival Analysis of Frail Patients With Localised Colorectal Cancer
The purpose of this study is to analyse the survival of frail patients with localized colorectal cancer who undergo surgical treatment in comparison with those with palliative treatment
- Conditions
- Colorectal Cancer, Surgery, Frailty
- Trial name
- NCT04422002
- Where
- Spain
- Volunteers
- 114 people
- Sponsor
- Corporacion Parc Tauli
Locoregional Recurrence, Breast Cancer
Postoperative Re-irradiaTion With and Without HYPERthermia, or Surgery Only: Toxicity, Quality of Life and Survival in Patients With Locoregional Recurrent Breast Cancer
In the Netherlands, breast cancer patients with locoregional recurrence (LRR) and intermediate- and high-risk factors are treated with surgery with or without postoperative re-irradiation with or without hyperthermia.
- Conditions
- Locoregional Recurrence, Breast Cancer, Re-irradiation, Hyperthermia
- Trial name
- RT-HYPE (NCT06452485)
- Testing
- No interventions, patient-reported outcomes (PROMs) and toxicity will be collected in both groups.
- Where
- Netherlands
- Volunteers
- 500 people
- Sponsor
- Amsterdam UMC, location VUmc
Lymphoma, Malignant Solid Neoplasm
Geriatric Evaluation and Management With Survivorship Health Education for Older Survivors of Cancer, GEM-S Trial
This phase III trial compares the effect of geriatric evaluation and management with survivorship health education (GEM-S) to usual care on patient-reported physical function in older survivors of cancer.
- Trial name
- GEM-S (NCT05006482)
- Testing
- Best Practice, Comprehensive Geriatric Assessment, Educational Intervention
- Where
- 45 sites in United States
- Volunteers
- 668 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Synchronous Metastasized Breast Cancer, Circulating Tumor Cells
Primary Operation in SYnchronous meTastasized InVasivE Breast Cancer
Primary Operation in synchronous metastasized invasive breast cancer to evaluate the use of local therapy
- Trial name
- POSYTIVE (NCT01015625)
- Testing
- Surgery, Surgery on Demand
- Where
- 14 sites in Austria
- Volunteers
- 90 people
- Sponsor
- Austrian Breast & Colorectal Cancer Study Group
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