Clinical trials: Survival , Tumor
Pancreatic Cancer Non-resectable
Progression-free Survival After MWA Plus Durvalumab and Tremelimumab for Unresectable Locally Advanced Pancreatic Cancer
This phase-2 monocenter non-randomized prospective clinical trial evaluates the effectiveness of minimally invasive microwave ablation plus immunotherapy for unresectable non-metastatic locally advanced pancreatic cancer.
- Trial name
- MIMIPAC (NCT04156087)
- Testing
- Durvalumab 50 MG/ML, Tremelimumab, Gemcitabine
- Where
- Belgium
- Volunteers
- 12 people
- Sponsor
- Baki Topal
Non Small Cell Lung Cancer Metastatic
Survival Efficacy of Combined Radiotherapy and Immunotherapy in Patients With Metastatic Non-small Cell Lung Carcinoma
The aim of this retrospective, multicenter, observational study is to evaluate the potential clinical benefit of adding radiotherapy (administered either concomitantly or sequentially) to immunotherapy in patients with metastatic…
- Trial name
- ARIS (NCT07111104)
- Testing
- Immunotherapy, Radiotherapy
- Where
- France
- Volunteers
- 350 people
- Sponsor
- Hopitaux Prives de Metz, Groupe UNEOS
Glioblastoma
Key Longitudinal Associations With Risk and Glioblastoma Outcomes
The goal of this observational study is to find out what factors affect the health and risks in adults with glioblastoma (GBM), a grade 4 brain cancer.
- Trial name
- Key LARGO (NCT06625684)
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Duke University
Covid19, Vaccination Refusal
Strategies to Continue Gynae-oncology Services in the Era of COVID-19 Outbreak: Concerns and Challenges in a Referral Centre in Malaysia
A short survey involving 100 participants was conducted online to explore the understanding of Covid 19 pandemic impact and importance of vaccination among cancer survivors.
- Conditions
- Covid19, Vaccination Refusal, Survivorship
- Trial name
- NCT05043155
- Where
- Malaysia
- Volunteers
- 100 people
- Sponsor
- Universiti Kebangsaan Malaysia Medical Centre
Breast Cancer
Individualizing Approaches to Surveillance Mammography in Older Breast Cancer Survivors - The I-MAMMO Study
This study evaluates the effectiveness of a Shared Decision-Making (SDM) toolkit designed to support older breast cancer survivors aged 80 and above in making informed decisions about continuing surveillance mammography.
- Trial name
- I-MAMMO (NCT07123649)
- Testing
- Shared Decision-Making Toolkit
- Where
- United States
- Volunteers
- 364 people, healthy volunteers welcome
- Sponsor
- Dana-Farber Cancer Institute
Carcinoma, Pancreatic Ductal
Predictive Factors for Resection and Survival in Type A Borderline Resectable Pancreatic Ductal Adenocarcinoma Patients After Neoadjuvant Therapy
Radical surgical resection is the only curative treatment option for pancreatic cancer, but borderline resectable tumors have a high probability of incomplete exeresis.
- Trial name
- PF-BARNA (NCT05489458)
- Testing
- Resection, No Resection
- Volunteers
- 100 people
- Sponsor
- BUSQUETS, JULI
Breast Cancer, Perioperative/Postoperative Complications
Correlation of Menstrual Cycle Phase at Time of Primary Surgery With 5-Year Disease-Free Survival in Women With Stage I or Stage II Breast Cancer
RATIONALE: Timing of breast cancer surgery may improve effectiveness of treatment and may help patients live longer. PURPOSE: Clinical trial to determine whether timing of primary surgery in relation to menstrual cycle is…
- Trial name
- NCT00002762
- Testing
- patient interviewing to obtain menstrual history, blood sampling
- Where
- 54 sites in United States, Canada
- Volunteers
- 1,118 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Hormone Receptor-positive Breast Cancer
Evaluate Efficacy and Safety of LACUDY for Improving Vaginal Environment in Breast Cancer Patient
Adjuvant hormone treatments for early breast cancer are associated with frequent bothersome side effects with major negative impact on patients' quality of life and treatment adherence.
- Trial name
- NCT05651087
- Testing
- LACUDY
- Volunteers
- 60 people
- Sponsor
- Gun Oh Chong
Overall Survival
Spleen-Preserving No. 10 Lymph Node Dissection in Gastric Cancer
This study is to conduct a randomized controlled trial of two kinds of radical gastrectomy for patients with proximal gastric cancer.
- Trial name
- NCT04050787
- Testing
- D2 Lymphadenectomy including No. 10, D2 lymphadenectomy excluding No. 10
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Jian Suo
MACE, Arrhythmia, Pericardial Effusion and Survival
Cardiac Safety Management and Immune Microenvironment Changes After Thoracic Radiotherapy: A Prospective Observational Study
The goal of this observational study is to learn about cardiac safety monitoring after thoracic radiotherapy in adults with thoracic tumors.
- Trial name
- NCT07669493
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Hebei Medical University Fourth Hospital
Neoplasm
Cancer in the Small Developing Island States of the Eastern Caribbean
Caribbean studies examining overseas cancer care were lacking patient-level data. Investigators will collect data from patients by establishing a cohort of survivors across six small island developing states (SIDS) (Antigua…
- Trial name
- CaSIDEC (NCT07695116)
- Testing
- Overeseas travel for care
- Where
- 6 sites in Antigua and Barbuda, Dominica and 4 more
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- Vaughan A. Lewis Institute for Research and Innovation
Neuroendocrine Carcinoma, Digestive Cancer
Efficacy of Neoadjuvant Chemotherapy in Terms of DFS in Patients With Localized Digestive Neuroendocrine Carcinomas
NEONEC is a single-phase, phase II study evaluating the efficacy of the 12-month neoadjuvant chemotherapy in patients with locally differentiated digestive NEC.
- Trial name
- NEONEC (NCT04268121)
- Testing
- Neoadjuvant treatment, Adjuvant treatment
- Where
- 14 sites in France
- Volunteers
- 78 people
- Sponsor
- GERCOR - Multidisciplinary Oncology Cooperative Group
Esophageal Neoplasms
The Predictive Value of CT-PET in Esophageal Cancer
A major focus of research in oncology is to identify patients who, following induction therapy, have a complete pathologic response, presenting opportunities for novel trials, including extended therapy or non-operative…
- Trial name
- NCT02385604
- Where
- Ireland
- Volunteers
- 250 people
- Sponsor
- St. James's Hospital, Ireland
Gastric Cancer
Hematological Dynamic Scores for Predicting Survival and Treatment Response for Advanced Gastric Cancer After Neoadjuvant Therapy
HMDLS, based on hematological markers, could effectively distinguish the long-term efficacy of AGC patients after NAT. The predictive performance of nomogram-HMDLS was better than ypTNM stage, achieving better prognostic…
- Trial name
- NCT06573307
- Where
- China
- Volunteers
- 442 people
- Sponsor
- Chang-Ming Huang, Prof.
Breast Carcinoma
Demographic , Clinicopathological Characteristics and Survival of Breast Cancer
The investigators will retrospectively study the demographic , clinicopathological characteristics and survival of breast cancer patients admitted to Assiut University hospital from the year 2015 to 2019
- Trial name
- NCT04316247
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assiut University
Cancer
Access to Care and Prognosis in Elderly With Cancer (INCAPAC Study)
The growing incidence of cancer associated to an aging population represents an epidemiologic reality that requires questioning access to care and prognosis in elderly with cancer, for which disparities have been highlighted.
- Trial name
- NCT03694171
- Testing
- Any cancer treatment
- Where
- France
- Volunteers
- 450 people
- Sponsor
- Institut Bergonié
Chronic Pain, Cancer
Immersive Multimedia as an Adjunctive Measure for Pain Control in Cancer Patients
This study seeks to explore the efficacy of immersive multimedia experiences as a practical adjunctive therapeutic intervention in the self-management of the chronic pain associated with cancer patients.
- Trial name
- NCT02995434
- Testing
- Virtual Reality Headset, 2D PC
- Where
- 3 sites in Canada
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Hypopituitarism, Radiotherapy-Induced Hypopituitarism
Improving Survivorship and Health-related Quality of Life in Patients With Primary Brain Tumours
Background: Approximately 480 primary, non-pituitary, brain tumours were diagnosed in Ireland each year between 1994 and 2013. Recent developments in treatment have greatly improved survival for younger patients in the 15-54 age…
- Conditions
- Hypopituitarism, Radiotherapy-Induced Hypopituitarism, Brain Tumor
- Trial name
- NCT06014398
- Testing
- Dynamic testing of Pituitary Function
- Where
- 2 sites in Ireland
- Volunteers
- 50 people
- Sponsor
- Royal College of Surgeons, Ireland
Neoplasms
Impact of Elimination or Reduction of Dietary Animal Proteins on Cancer Progression and Survival - A Pilot Study
The purposes of this study are to test the hypothesis that elimination or reduction of dietary animal proteins leads to an improved prognosis in tumor patients to estimate the effect size and thus to enable sample size…
- Trial name
- NCT02437474
- Testing
- Omnivorous diet, Lacto-ovo-vegetarian diet, Vegan diet
- Where
- Austria
- Volunteers
- 326 people
- Sponsor
- Rosa Aspalter
Metastatic Colorectal Cancer
A Phase III Study of Xilonix in Patients With Advanced Colorectal Cancer
The purpose of this study is to determine if the True Human Monoclonal antibody Xilonix (MABp1) can prolong the life of colorectal carcinoma patients that are refractory to standard therapy.
- Trial name
- XCITE (NCT01767857)
- Testing
- Xilonix
- Where
- 113 sites in United States, Australia and 11 more
- Volunteers
- 643 people
- Sponsor
- Janssen Research & Development, LLC
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.