Clinical trials: Survival , Tumor
Breast Cancer Female
Survival Benefits of Statins in Breast Cancer Patients
In this study, we compared the survival benefit of breast cancer patients with dyslipidemia (low and medium risk of ASCVD). The control group used dietary intervention instead of statins intervention.
- Trial name
- SBSBC (NCT03971019)
- Testing
- statins, Dietary intervention group (control group)
- Where
- China
- Volunteers
- 314 people
- Sponsor
- Peking Union Medical College Hospital
Breast Cancer
Letrozole in Treating Postmenopausal Women Who Have Received Hormone Therapy for Hormone Receptor-Positive Breast Cancer
RATIONALE: Estrogen can cause the growth of breast cancer cells. Hormone therapy using letrozole may fight breast cancer by lowering the amount of estrogen the body makes.
- Trial name
- NCT00382070
- Testing
- Letrozole
- Where
- 806 sites in United States, Canada and 1 more
- Volunteers
- 3,966 people
- Sponsor
- NSABP Foundation Inc
Metastatic Breast Cancer
Systemic Therapy With or Without Upfront Surgery in Metastatic Breast Cancer
SUBMIT is a clinical trial that intends to answer the question whether up front breast surgery in patients with primary distant metastatic breast cancer will result in an improvement of the 2-year survival compared to the…
- Trial name
- SUBMIT (NCT01392586)
- Testing
- upfront breast surgery, systemic therapy
- Where
- 26 sites in Netherlands
- Volunteers
- 10 people
- Sponsor
- Jeroen Bosch Ziekenhuis
Laryngeal Cancer
Nomograms to Precisely Predict Conditional Risk of Survival for Patients With Laryngeal Cancer
Advanced laryngeal squamous cell carcinoma (SCC) remains a highly morbid and fatal disease despite aggressive interventions. Mortality is high in this cohort: laryngeal cancer affects over 13 000 patients in the United States…
- Trial name
- NCT03747783
- Testing
- Radical Operation
- Where
- China
- Volunteers
- 400 people
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
Acute Lymphoblastic Leukemia
Second Malignant Neoplasms After Childhood ALL Therapy
Development of a second neoplasm (SMN) during or after therapy for childhood acute lymphoblastic leukemia (ALL) is a rare event generally associated with a poor prognosis.
- Trial name
- PdL-SMN1 (NCT01476462)
- Where
- Denmark
- Volunteers
- 642 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Cancer Survivor, Early-Stage Breast Carcinoma
Mindfulness Meditation or Survivorship Education in Improving Behavioral Symptoms in Younger Stage 0-III Breast Cancer Survivors (Pathways to Wellness)
This randomized phase III trial studies how well mindfulness meditation or survivorship education work in improving behavioral symptoms in younger stage 0-III breast cancer survivors.
- Conditions
- Cancer Survivor, Early-Stage Breast Carcinoma, Stage 0 Breast Cancer, Stage IA Breast Cancer
- Trial name
- PTW (NCT03025139)
- Testing
- Educational Intervention, Laboratory Biomarker Analysis, Meditation Therapy
- Where
- 3 sites in United States
- Volunteers
- 96 people
- Sponsor
- Jonsson Comprehensive Cancer Center
Breast Cancer
Study to Compare Zoladex™ 10.8 mg With Zoladex 3.6 mg in Pre-menopausal Women With Breast Cancer
The purpose of this study is to examine the efficacy and safety as well as the characteristics of the female hormone and study medications after administration in pre-menopausal women with estrogen receptor positive advanced…
- Trial name
- NCT01073865
- Testing
- ZD9393 (Zoladex) 10.8 mg, ZD9393 (Zoladex) 3.6 mg
- Where
- 55 sites in India, Japan and 4 more
- Volunteers
- 222 people
- Sponsor
- AstraZeneca
Prostatic Neoplasms
An International Prospective Open-label, Randomized, Phase III Study Comparing 177Lu-PSMA-617 in Combination With Standard of Care (SoC), Versus SoC Alone, in Adult Male Patients With Metastatic Hormone Sensitive Prostate Cancer (mHSPC)
The purpose of this study is to evaluate the efficacy and safety of 177Lu-PSMA-617 in combination with Standard of Care (SOC), versus Standard of Care alone, in adult male patients with Metastatic hormone sensitive prostate…
- Trial name
- PSMAddition (NCT04720157)
- Testing
- 177Lu-PSMA-617, 68Ga-PSMA-11, ARDT
- Where
- 164 sites in United States, Austria and 17 more
- Volunteers
- 1,144 people
- Sponsor
- Novartis Pharmaceuticals
Breast Cancer
Responsiveness to Acute Changes in Exercise and Relaxation (RACER) Trial
The purpose of this acute study is to compare the combined effects of aerobic exercise and relaxation training on fatigue and its related cognitive components, among breast cancer survivors.
- Trial name
- RACER (NCT03702712)
- Testing
- Aerobic Exercise and Relaxation, Aerobic Exercise Only, Relaxation Only
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Nasopharyngeal Carcinoma
The Influence of Anxiety and Depression on Survival in Nasopharyngeal Carcinoma Patients
This is a prospective, observational cohort study aimed to explore the influence of anxiety and depression to long term survival in nasopharyngeal carcinoma patients.
- Trial name
- NCT03290001
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Sun Yat-sen University
Locally Advanced Carcinoma, Metastatic Cancer
Evaluation of Efficacy of Comprehensive Genomic Tumour Profiling (CGP) From Liquid and/or Tissue Biopsy in Patients With Locally Advanced and/or Metastatic Solid Cancer
The aims of this study are to evaluate the efficacy of comprehensive genomic tumour profiling (CGP) from liquid and/or tissue biopsy in patients with locally advanced and/or metastatic solid cancer.
- Trial name
- SOUND (NCT05032092)
- Testing
- Next Generation Sequencing, Biomarker Monitoring
- Where
- 6 sites in Austria
- Volunteers
- 235 people
- Sponsor
- Medical University of Graz
HCC
Radiofrequency Ablation Accompanied With Spontaneous Sorafenib in Early to Intermediate Stage HCC
Radiofrequency ablation (RFA)can be curative with small localized HCCs up to 5 cm in diameter. However, the long-term prognosis is not satisfactory due to the high incidence of recurrence.Multimodality treatments are needed to…
- Trial name
- NCT02187081
- Testing
- radiofrequency ablation plus Sorafenib, Radiofrequency ablation
- Where
- China
- Volunteers
- 380 people
- Sponsor
- Southwest Hospital, China
Prostate Cancer
Energy Balance for Prostate Cancer Survivorship
The purpose of this study is to evaluate the effectiveness of a weight management program for men undergoing a prostatectomy by seeing if the program is easy to follow, impacts weight gain, and reduces risk of cancer recurrence…
- Trial name
- NCT02252484
- Testing
- Weight Loss Program, Standard of Care
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Jill Hamilton-Reeves, PhD RD LD
Gastrointestinal Cancers - Stomach, Gastrointestinal Cancers - Colorectal
A Novel Nomogram to Predict the Postoperative Overall Survival in Gastrointestinal Cancer Patients
This multicenter retrospectively observational cohort study was conducted on participants with histologically confirmed gastric and colorectal cancer who underwent radical surgery in 11 medical centers in China from August 1…
- Conditions
- Gastrointestinal Cancers - Stomach, Gastrointestinal Cancers - Colorectal, Prognosis, Survival Analysis
- Trial name
- NCT05620537
- Testing
- observation
- Where
- China
- Volunteers
- 808 people
- Sponsor
- Wang Xinying
Nutrition in Cancer Survival and Treatment
Delivery of Nutritional Services in Nicaragua
This study investigates nutritional status, at predefined points in therapy, and the association with outcomes in children and adolescents undergoing treatment for cancer in institutions under Asociación de Hemato-Oncología…
- Trial name
- NCT04031586
- Where
- Nicaragua
- Volunteers
- 50 people
- Sponsor
- Columbia University
Second Cancer, Survivorship
The Prospective Observational COMPRAYA Cohort Study
Rationale: Childhood cancer survivorship attracts attention globally, because successes in treatment have led to increasing number of survivors who reach adulthood, in which survivorship issues affecting health-related quality of…
- Conditions
- Second Cancer, Survivorship, Fertility Issues, Distress, Emotional
- Trial name
- COMPRAYA (NCT04682470)
- Testing
- No intervention ; observational
- Where
- Netherlands
- Volunteers
- 4,000 people
- Sponsor
- The Netherlands Cancer Institute
Outcomes of Smoker and Drinker After Esophagectomy
Outcomes of Smoker and Drinker With Esophageal Squamous Cell Carcinoma After Esophagectomy
Our study demonstrates that patients who did not consume alcohol or smoke had a significant advantage in overall survival (OS) after undergoing esophagectomy.
- Trial name
- OSinEC (NCT06269341)
- Testing
- No intervention
- Where
- China
- Volunteers
- 2,957 people
- Sponsor
- Sichuan Cancer Hospital and Research Institute
Myelofibrosis
European Registry for Myeloproliferative Neoplasms (MPNs) - Update of ERNEST Study
The Fondazione per la Ricerca Ospedale di Bergamo (FROM) decided to propose and promote the completion of ERNEST registry: the aim of the project is to obtain up-to-date estimates of clinical outcome of these patients in primary…
- Trial name
- ERNEST (NCT04153305)
- Where
- 6 sites in Italy, Spain and 1 more
- Volunteers
- 1,010 people
- Sponsor
- FROM- Fondazione per la Ricerca Ospedale di Bergamo- ETS
Prostate Cancer
HDR Brachytherapy as Monotherapy for Low and Intermediate Risk Prostate Cancer
The purpose of this study is to evaluate High-dose rate (HDR) brachytherapy (1 vs 2 fractions on single implant) as monotherapy for the treatment of low risk and intermediate risk prostate cancer
- Trial name
- BRP2 (NCT03424694)
- Testing
- HDR brachytherapy as monotherapy
- Where
- Canada
- Volunteers
- 199 people
- Sponsor
- CR-CSSS Champlain-Charles-Le Moyne
Breast Cancer, Hot Flashes
Reproductive Health Survivorship Care Plan Pilot
Most young breast cancer patients undergo chemotherapy and/or endocrine therapy, treatments that impair ovarian function and result in significant reproductive health late effects.
- Conditions
- Breast Cancer, Hot Flashes, Vaginal Dryness, Estrogen Deprivation Symptoms
- Trial name
- NCT02176083
- Testing
- Text message management prompts
- Where
- 2 sites in United States
- Volunteers
- 38 people
- Sponsor
- University of California, San Diego
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