Clinical trials: Survival , Tumor
Colorectal Cancer
Preoperative Non-steroidal Anti-inflammatory Drugs(NSAID) to Colorectal Cancer Patients
The study is designed to evaluate effects of NSAIDs on immune activity inside and close to tumor tissue in patients with colorectal cancer.
- Trial name
- NCT00473980
- Testing
- Indomethacin, celecoxib, esomeprazole
- Where
- Sweden
- Volunteers
- 28 people
- Sponsor
- Göteborg University
Adenoid Cystic Carcinoma, Sinonasal Carcinoma
SPARE-1st: Surgery Alone vs Surgery Plus Postoperative Radiotherapy for Sinonasal Adenoid Cystic Carcinoma
Background: Sinonasal adenoid cystic carcinoma (ACC) is a rare type of cancer that starts in the nasal cavity or sinuses. Although surgery can remove the tumor, doctors often recommend radiation therapy after surgery to reduce…
- Trial name
- SPARE-1st (NCT07563088)
- Testing
- Postoperative Radiotherapy, Observation
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Eye & ENT Hospital of Fudan University
Survival
Perioperative Chemotherapy Combined With HIPEC for High-risk Advanced Gastric Cancer
The investigators intend to conduct a randomized controlled study to find if combining HIPEC (hyperthermic intraperitoneal perfusion chemotherapy) with post-neoadjuvant chemotherapy D2 resection could improve survival for…
- Trial name
- HIPEC (NCT02960061)
- Testing
- Neoadjuvant chemotherapy, D2 radical resection, Hyperthermic intraperitoneal perfusion chemotherapy
- Where
- China
- Volunteers
- 640 people
- Sponsor
- Sixth Affiliated Hospital, Sun Yat-sen University
Lymphoma, Extranodal NK-T-Cell
P-Gemox Regimen as First-line Chemotherapy in NK/T Lymphoma Patiens
This prospective study was conducted to evaluate the efficacy and safety profiles of first-line combined gemcitabine, oxaliplatin, and Pegaspargase (P-Gemox) in newly diagnosed, nasal type, extranodal natural killer/T-cell…
- Trial name
- NCT02533323
- Testing
- gemcitabine, oxaliplatin, pegaspargase
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Sun Yat-sen University
Cancer, Survivorship
Shared Healthcare Actions and Reflections Electronic Systems in Survivorship
The primary purpose of this study is conduct a pilot study testing the study protocols, implementation program, and mixed-methods data collection.
- Conditions
- Cancer, Survivorship, Hematopoietic and Lymphoid Cell Neoplasm, Malignant Solid Neoplasm
- Trial name
- NCT04337203
- Testing
- SHARE-S Implementation Program
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Wake Forest University Health Sciences
Prostate Cancer
Predictive Role of [11C] Choline PET/CT on Survival in Prostate Cancer Patients With Biochemical Failure.
Several studies have shown that the PET/CT study with Choline is of great use in the restaging of patients with prostate cancer who present a recurrence of biochemical disease following primary treatment.
- Trial name
- NCT06168890
- Testing
- PET/CT with choline in the restaging phase of prostate cancer.
- Volunteers
- 195 people
- Sponsor
- IRCCS San Raffaele
Neoplasm Malignant
A Trial of a Multimodal Lifestyle Intervention to Optimize Survivorship After Cancer
To examine the efficacy of a 10-week multimodal lifestyle program, versus waitlist control, on cardiorespiratory fitness capacity and body weight in survivors of cancer.
- Trial name
- Small Steps (NCT04987359)
- Testing
- Multimodal Lifestyle Program
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Pennington Biomedical Research Center
Prostate Carcinoma
Social Determinants of Migrant Health Factors Impacting Prostate Cancer Care and Survivorship Among Sub-Saharan African and Caribbean Immigrant Men
This study is being done to understand what social factors affect health decisions for those who have immigrated from another country by examining how the immigration from Sub-Sahara Africa affects the experiences of participants…
- Trial name
- NCT06472817
- Testing
- Non-Interventional Study
- Where
- 3 sites in United States
- Volunteers
- 80 people
- Sponsor
- Mayo Clinic
Breast Cancer
The Change Cycle Intervention for Improving Quality of Life in Breast Cancer Survivors
This study is proposed to assess long-term Quality of Life issues in breast cancer survivors by measuring the impact on the quality of life made by the structured "Change Cycle Work Shop" coping class as compared to current local…
- Trial name
- CCIP (NCT01734499)
- Testing
- Coping Class, Standard of Care, FACT-B Quality of Life
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Texas Tech University Health Sciences Center
Colorectal Cancer, ERAS
Compliance With ERAS and Five Year Survival After Colorectal Cancer Treatment
The Enhanced Recovery after Surgery (ERAS) protocol has transformed perioperative care, representing a significant paradigm shift in managing colorectal cancer patients.
- Trial name
- NCT06342687
- Testing
- High compliance with ERAS protocol
- Where
- Poland
- Volunteers
- 468 people
- Sponsor
- Jagiellonian University
Classical Hodgkin Lymphoma, Diffuse Large B Cell Lymphoma (DLBCL)
Lifestyles Implemented-Survivorship Care Plan In Lymphoma Survivors
This is a prospective randomized open-label, multicenter, 2-arm study to assess the role of healthy LifeStyle implemented Survivorship Care Plan (LS-SCP) in modifying the Quality of Life (QoL) in a population of long-term…
- Conditions
- Classical Hodgkin Lymphoma, Diffuse Large B Cell Lymphoma (DLBCL), Primary Mediastinal Large B-cell Lymphoma (PMBCL)
- Trial name
- NCT05934084
- Testing
- Lifestyles Implemented-Survivorship Care Plan (LS-SCP)
- Where
- 40 sites in Italy
- Volunteers
- 552 people
- Sponsor
- Fondazione Italiana Linfomi - ETS
Advanced Prostate Cancer
A Long-term Observational Study Cohort in Patients With Advanced Prostate Cancer
The purpose of the protocol is to assess the rate of castration resistance, disease progression and overall survival over a 3-year period post-androgen deprivation therapy (ADT) induction in a study cohort of patients with…
- Trial name
- TRIPTOCARE LT (NCT01383863)
- Where
- 35 sites in Denmark, France and 5 more
- Volunteers
- 180 people
- Sponsor
- Ipsen
Unresectable Hepatocellular Carcinoma
Long-Term Survival With Lenvatinib-Based Therapy in Unresectable Liver Cancer
This study reviewed real-world outcomes of patients with unresectable hepatocellular carcinoma who received lenvatinib-based treatment.
- Trial name
- NCT07298538
- Where
- China
- Volunteers
- 800 people
- Sponsor
- Tianjin Medical University Cancer Institute and Hospital
Stage Ib Lung Carcinoma
Multicenter Randomized Controlled Trial Adjuvant Chemotherapy vs Observation in pStage Ib Lung Adenocarcinoma
Researchers developed the nomogram which evaluate the risk of recurrence after surgical resection, and found that the stage 1 NSCLC patients with more than 104 point of nomogram showed similar recurrence rate to the recurrence…
- Trial name
- NCT02281708
- Testing
- vinorelbine plus cisplatin
- Where
- South Korea
- Volunteers
- 1,012 people
- Sponsor
- Seoul National University Hospital
Lung Cancer, Non-Small Cell
Sleeve Lobectomy for Lung Cancer in Minimally Invasive Surgical Techniques
The goal of this multicenter observational study is to evaluate the long-term survival and perioperative outcomes of sleeve lobectomy in robotic-assisted thoracic surgery (RATS) for patients with central lung cancer when compared…
- Trial name
- NCT06687408
- Testing
- RATS Group, VATS group
- Where
- 3 sites in China
- Volunteers
- 450 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Colorectal Cancer, Chemotherapy Effect
Comparative Study of Mitomycin and Lobaplatin in Advanced Colorectal Cancer Patients With Radical Surgery Combined With Hyperthermic Intraperitoneal Chemotherapy
This study is a prospective, randomized, comparative clinical trial conducted by Wuhan Union Hospital and aim to compare the therapeutic effects of Mitomycin and Lobaplatin in the treatment of advanced colorectal cancer patients…
- Conditions
- Colorectal Cancer, Chemotherapy Effect, Surgery, Metastasis
- Trial name
- WUHIPEC02 (NCT04845490)
- Testing
- Mitomycin, Lobaplatin
- Volunteers
- 201 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Anxiety Disorder, Cognitive/Functional Effects
Health Education Materials With/Out a Physical Activity Program for Patients Who Have Undergone Treatment for High-Risk Stage II or Stage III Colon Cancer
RATIONALE: Participating in a physical activity program designed to increase free time physical activity and receiving written health education materials may influence the chance of cancer recurring as well as impact on physical…
- Conditions
- Anxiety Disorder, Cognitive/Functional Effects, Colorectal Cancer, Depression
- Trial name
- CHALLENGE (NCT00819208)
- Testing
- exercise intervention, counseling intervention, educational intervention
- Where
- 47 sites in United States, Australia and 4 more
- Volunteers
- 889 people
- Sponsor
- Canadian Cancer Trials Group
Non-small Cell Lung Cancer
Role of PET Scan in the Evaluation of Early Response to Maintenance Treatment in Advanced Non-small-cell Lung Cancer
Non small cell lung cancer is the first cause of cancer related death in France and is becoming an increasing health problem in developing countries.
- Trial name
- CALMETTE (NCT02507518)
- Testing
- PET scan imaging
- Where
- 5 sites in France
- Volunteers
- 80 people
- Sponsor
- Centre Henri Becquerel
Malignant Pleural Mesotheliomas (Mpm), Malignant Pleural Effusions (Mpe)
Phase I Evaluation of Immunotoxin LMB-100 Administered by Normothermic, Intrapleural Perfusion Following Cytoreductive Surgery in Participants With Pleural Mesotheliomas, or Pleural Effusions From Cancers Expressing Mesothelin
Background: Cancers that spread into the thin tissue lining your lungs (pleura) cause serious illness. They often recur when removed.
- Conditions
- Malignant Pleural Mesotheliomas (Mpm), Malignant Pleural Effusions (Mpe), Epithelial Tumors, Malignant, Pleural Effusions, Malignant
- Trial name
- NCT05375825
- Testing
- Cytoreductive surgery, LMB-100, Immunohistochemical Assay for Mesothelin
- Where
- United States
- Sponsor
- National Cancer Institute (NCI)
Oligodendrogliomas
Research of Molecular and Metabolic Markers in Oligodendrogliomas Comparatively to Other Brain Tumours
At present, diagnosis of oligodendroglioma is made on histological and radiographic criteria in the French Mayo-Ste Anne classification.
- Trial name
- NCT00213876
- Where
- France
- Volunteers
- 189 people
- Sponsor
- University Hospital, Strasbourg, France
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