Clinical trials: Survival , Tumor
Spine Tumor
Predictors of Mortality and Morbidity in the Surgical Management of Primary Tumors of the Spine
Within defined groups of primary malignant and benign bone and soft tissue spine tumors, what variables (clinical, diagnostic, therapeutic, and/or demographic) are associated with overall survival?
- Trial name
- PT (NCT01643174)
- Where
- Canada
- Volunteers
- 1,600 people
- Sponsor
- AO Foundation, AO Spine
Hepatocellular Carcinoma
Safety and Efficacy of Oncoxin in Hepatocellular Carcinoma (HCC)
Oncoxin is safe and results in improved survival in patients with hepatocellular carcinoma
- Trial name
- NCT01392131
- Testing
- Oncoxin, Supportive treatment
- Where
- Bangladesh
- Volunteers
- 40 people
- Sponsor
- Clinical Research Organization, Dhaka, Bangladesh
Breast Cancer, Survivorship
Dance Study for Post-surgical Pain in Breast Cancer Survivors
The purpose of this study is to examine how a 12-week, virtual dance program may improve pain and quality of life in participants with persistent post-surgical pain, or PPSP, following mastectomy or lumpectomy.
- Conditions
- Breast Cancer, Survivorship, Pain, Postoperative
- Trial name
- NCT06758102
- Testing
- Dance Program
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Dana-Farber Cancer Institute
Brain Metastases, Adult, Primary Brain Tumor
Survivorship Study of Cancer Patients Who Received Cranial Radiation Therapy
This study represents a survivorship protocol that focuses on cognition and health-related quality of life (HRQoL) in cancer patients that have received prior brain irradiation.
- Conditions
- Brain Metastases, Adult, Primary Brain Tumor, Lung Cancer
- Trial name
- SPiRiT (NCT04567251)
- Testing
- Noona® application
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Duke University
Carcinoma, Pancreatic Ductal
Impact of Nationwide Enhanced Implementation of Best Practices in Pancreatic Cancer Care (PACAP-1)
PACAP-1 will evaluate to what extent an enhanced implementation of best practices in pancreatic cancer care leads to a prolonged survival and improvement of quality of life as compared to current practice.
- Trial name
- PACAP-1 (NCT03513705)
- Testing
- Best practices in pancreatic cancer care
- Where
- 17 sites in Netherlands
- Volunteers
- 4,000 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Progression-free Survival Was Defined From Date of Surgery to Disease Progression Post-surgery or Death or Last Follow-up, Overall Survival Was Defined as Time From Surgery to Death From Any Cause or Last Follow-up
Observational, Bivariate Analysis of Clinical Big Data in Patients With Cervical Cancer
This is a large non-interventional observational bidirectional study planned to collect clinically relevant data and prognostic follow-up information of patients with cervical cancer who were seen at our center from 2010.01.01 to…
- Trial name
- NCT06480617
- Where
- China
- Volunteers
- 3,000 people
- Sponsor
- Anhui Provincial Hospital
Obesity, Cancer
Using Tailored mHealth Strategies to Promote Weight Management Among Adolescent and Young Adult Cancer Survivors
The AYA WELL study is a 2-arm randomized clinical trial to test the efficacy of a theory-based, mHealth weight management intervention adapted specifically for adolescent and young adult cancer survivors compared to a self-guided…
- Conditions
- Obesity, Cancer, Physical Activity, Cancer Survivorship
- Trial name
- AYAWell (NCT06848491)
- Testing
- AYA WELL Intervention, Self-Guided
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Salivary Gland Cancer
Cabozantinib in Advanced Salivary Gland Cancer Patients
Phase 2 clinical trial on the efficacy of cabozantinib in locally advanced, recurrent and/or metastatic salivary gland cancer patients.
- Trial name
- Cabo ASAP (NCT03729297)
- Testing
- Cabozantinib
- Where
- Netherlands
- Volunteers
- 25 people
- Sponsor
- Radboud University Medical Center
Cholangiocarcinoma
Prognostic Factors for Survival in Patients With Cholangiocarcinoma
The objective of this retrospective study is to determine the survival rates of CCA patients based on different therapeutic approaches.
- Trial name
- NCT06369480
- Testing
- Resection/Ablation of tumor, Palliative chemotherapy, Neoadjuvant chemotherapy
- Where
- Denmark
- Volunteers
- 2,000 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Breast Cancer, Prostate Cancer
Survivorship Promotion In Reducing IGF-1 Trial
This is a prospective, single-center randomized trial with three arms, and an allocation ratio of 1:1:1. The study design is an efficacy study to evaluate the effect of metformin and coach-directed behavioral weight loss versus…
- Conditions
- Breast Cancer, Prostate Cancer, Lung Cancer, Colon Cancer
- Trial name
- SPIRIT (NCT02431676)
- Testing
- Metformin, Coach Directed Behavioral Weight Loss, Self-control weight loss
- Where
- United States
- Volunteers
- 121 people
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Prostate Cancer
Cooking Class Intervention Project for Men With Prostate Cancer and Their Partners
Prostate cancer is one of the most commonly diagnosed cancers in Canada, with 24,000 new cases estimated for 2015. Prostate cancer patients often live with uncomfortable side effects of treatment, such as a decrease in bone…
- Trial name
- NCT02954289
- Testing
- Dietary intervention
- Where
- Canada
- Volunteers
- 44 people
- Sponsor
- University of British Columbia
Small Cell Lung Cancer
A Study of Subjects With Previously Untreated Extensive-Stage Small-Cell Lung Cancer (SCLC) Treated With Platinum Plus Etoposide Chemotherapy With or Without Darbepoetin Alfa
The purpose of this study is to evaluate whether increasing or maintaining hemoglobin concentrations with darbepoetin alfa, when administered with platinum-containing chemotherapy in subjects with previously untreated…
- Trial name
- NCT00119613
- Testing
- darbepoetin alfa
- Volunteers
- 600 people
- Sponsor
- Amgen
Advanced Malignant Mesothelioma, Carcinoma of the Appendix
Quality of Life and Survivorship Care in Patients Undergoing Hyperthermic Intraperitoneal Chemotherapy (HIPEC)
RATIONALE: An orientation and patient education program and telephone counseling may help improve the quality of life in patients with peritoneal surface malignancies.
- Conditions
- Advanced Malignant Mesothelioma, Carcinoma of the Appendix, Ovarian Sarcoma, Ovarian Stromal Cancer
- Trial name
- HOPE (NCT01126346)
- Testing
- HIPEC Orientation, Consultation with Survivorship Navigator, Questionnaires
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Wake Forest University Health Sciences
Cancer, Survivorship
Cancer Within a Pandemic: A Telemental Health Intervention
The purpose of this research study is to test an online support group designed to help young adults who have had cancer treatment to manage their mood during a pandemic.
- Conditions
- Cancer, Survivorship, Depression, Anxiety
- Trial name
- NCT04659993
- Testing
- Telemental Health Sessions, Support Groups and Questionnaires
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Wake Forest University Health Sciences
Multiple Myeloma
2015-12: A Study Exploring the Use of Early and Late Consolidation/Maintenance Therapy
This study will assess whether adding one of the newest multiple myeloma therapies, daratumumab, into the Total Therapy approach helps patients live longer with fewer side effects
- Trial name
- NCT03004287
- Testing
- Carfilzomib, Thalidomide, Dexamethasone
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Arkansas
Locally Advanced Breast Cancer
NEOZOL_Follow-up Study
Breast cancer is the most common cancer in women and is the leading cause of death from cancer in France. The main types of treatment used to treat breast cancer are surgery, chemotherapy, radiotherapy, hormone therapy and…
- Trial name
- NEOZOL_FU (NCT04899713)
- Testing
- Survival survey
- Where
- 11 sites in France
- Volunteers
- 50 people
- Sponsor
- Hospices Civils de Lyon
Melanoma, Breast Cancer
Survival Monitoring in Russian Cancer Registries
This study aims to establish a holistic framework for continuous cancer survival surveillance in Russian regions with high-quality population-based cancer registry data.
- Conditions
- Melanoma, Breast Cancer, Oncology, Colon Cancer
- Trial name
- SURVIMON (NCT06043947)
- Where
- Russia
- Volunteers
- 100,000 people
- Sponsor
- N.N. Petrov National Medical Research Center of Oncology
Cervical Cancer
Intermediate Risk Cervical Cancer: Radical Surgery +/- Adjuvant Radiotherapy
The objective of the trial is to evaluate if adjuvant (chemo)radiation is associated with a disease-free survival benefit after radical surgery in patients with intermediate risk cervical cancer.
- Trial name
- CERVANTES (NCT04989647)
- Testing
- No adjuvant therapy, Adjuvant radiotherapy
- Where
- Czechia
- Volunteers
- 514 people
- Sponsor
- The Central and Eastern European Gynecologic Oncology Group
Esophageal Squamous Cell Carcinoma
Pre-Operative Pembrolizumab + Chemoradiation in Patients With Locally Advanced Esophageal Squamous Cell Carcinoma
To investigate the safety and activity of preoperative pembrolizumab combined with chemoradiotherapy for resectable esophageal squamous cell carcinoma (ESCC) ,20 patients enrolled in Phase Ib PALACE-1(NCT03792347).The results…
- Trial name
- PALACE-2 (NCT04435197)
- Testing
- Pembrolizumab Injection
- Where
- 2 sites in China
- Volunteers
- 143 people
- Sponsor
- Ruijin Hospital
Multiple Myeloma Survival Outcome, Multiple Myeloma and Malignant Plasma Cell Neoplasms
Multiple Myeloma Extramedulary Disease Samples FFPE
This observational study aims to evaluate the feasibility of assembling a retrospective cohort of formalin-fixed paraffin-embedded (FFPE) tissue samples from patients with extramedullary multiple myeloma, together with their…
- Trial name
- MMExFFPE (NCT07354555)
- Where
- France
- Volunteers
- 15 people
- Sponsor
- BIWAKO
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