Clinical trials: Survival , Tumor
Non Small Cell Lung Cancer
20K Distributed Learning Challenge
Machine learn a predictive model from more than 20.000 non-small cell lung cancer patients from more than 5 health care providers from more than 5 countries.
- Trial name
- NCT03564457
- Testing
- No interventions will take place (observational)
- Where
- Netherlands
- Volunteers
- 20,000 people
- Sponsor
- Maastricht Radiation Oncology
Head and Neck Squamous Cell Carcinoma, Body Image Disturbance
Building a Renewed ImaGe After Head & Neck Cancer Treatment
This study will evaluate whether a time-limited cognitive behavioral therapy (CBT) intervention in the post-treatment time period can address body image disturbance (BID) in patients with surgically-treated head and neck cancer…
- Trial name
- BRIGHT (NCT03518671)
- Testing
- cognitive behavioral therapy, face to face, cognitive behavioral therapy, telemedicine
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Medical University of South Carolina
Cancer Survivor, Healthy Subject
Survivorship Care Plan in Promoting Physical Activity in Breast or Colorectal Cancer Survivors in Wisconsin
This randomized pilot clinical trial studies how well survivorship care plan works in promoting technology-based physical activity in breast or colorectal cancer survivors in Wisconsin.
- Conditions
- Cancer Survivor, Healthy Subject, Stage I Colorectal Cancer, Stage IA Breast Cancer
- Trial name
- NCT02677389
- Testing
- Educational Intervention, Internet-Based Intervention, Monitoring Device
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Survivorship
LiveWell: An Adapted Dialectical Behavioral Therapy Skills Training Protocol for Patients Living With Metastatic Lung Cancer
In this pilot randomized controlled trial, patients with metastatic non-small cell lung cancer and at least mild distress (N=80) will be randomized to receive LiveWell, an adapted Dialectical Behavioral Therapy (DBT) Skills…
- Trial name
- NCT07177846
- Testing
- LiveWell: An Adapted Dialectical Behavioral Therapy Skills Training Program
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Medical University of South Carolina
Survivorship, Quality of Life
Neuromodulation of Central Sensory Integration to Improve Postural Control
The objective is to evaluate if neuromodulation of the PFC can acutely improve sensory integration for balance performance in OTTBCS.
- Conditions
- Survivorship, Quality of Life, Cognitive Deficits, Mild
- Trial name
- NCT06610617
- Testing
- transcranial direct current stimulation (tDCS)
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- University of Pittsburgh
Overall Survival, Postoperative Complications
Clinical Value of Left Colic Artery in Laparoscopic Radical Rectectomy
Colorectal cancer is one of the most common tumors in Asia. According to the recent research, surgical procedure could provide more treatment benefit in rectal cancer.
- Trial name
- NCT03349788
- Testing
- LCA-nP, LCA-P
- Where
- China
- Volunteers
- 354 people
- Sponsor
- Shanghai Minimally Invasive Surgery Center
Adenoid Cystic Carcinoma, Sinonasal Carcinoma
Surgery Plus Postoperative Radiotherapy for T4 Sinonasal Adenoid Cystic Carcinoma
This observational study follows patients with T4 stage sinonasal adenoid cystic carcinoma (a rare cancer of the nasal cavity/sinuses) who receive standard treatment: surgery followed by postoperative radiotherapy.
- Trial name
- SPORT-SNACC (NCT07652489)
- Testing
- Surgery
- Where
- 6 sites in China
- Volunteers
- 70 people
- Sponsor
- Eye & ENT Hospital of Fudan University
Chemotherapy-related Cognitive Impairment
Evaluating Cognitive Changes on Patients in Chemotherapy (ECCPC)
This randomized clinical trial aims to evaluate the impact of a structured low-intensity exercise program on cognitive function in adult cancer patients undergoing chemotherapy.
- Trial name
- (ECCPC) (NCT06950190)
- Testing
- Low-Intensity Walking Intervention, Control Group Intervention
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Ellis Medicine
Survival Without Progression
A Clinical Trial Using Metronomic Oral Low-dose Cyclophosphamide Alternating With Low-dose Oral Methotrexate With Continuous Celecoxib and Weekly Vinblastine in Children and Adolescents With Relapsed or Progressing soliD Tumours.
To establish the anti-tumour effect of this metronomic combination regimen defined by progression-free survival (PFS) after two cycles of treatment (4 months) and 12 months of treatment, as well as response rate after any number…
- Trial name
- SFCE METRO 01 (NCT01285817)
- Testing
- celecoxib, Vinblastine, Cyclophosphamide , methotrexate ,
- Where
- France
- Volunteers
- 79 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Rectal Cancer
The Pandemic's Effect on Diagnosis and Treatment of Rectal Cancer
Colorectal cancer is common with an annual prevalence of 6000. The majority can be cured and the five year survival rate is over 60%. In december 2019 reports came in about SARS-Cov-2, which later was named Covid-19.
- Trial name
- CovidRC (NCT05328960)
- Testing
- Diagnosed during or not during the pandemic
- Where
- Sweden
- Volunteers
- 8,000 people
- Sponsor
- Sahlgrenska University Hospital
Acute Myeloid Leukemia
Elderly Patients With Acute Myeloid Leukemia (AML), Maintenance Phase After Complete Remission (CR)
Phase II Multicentric Trial Open Label, Multicenter, randomized to evaluate the efficacy of a Maintenance Therapy in First Complete Remission After Induction for Elderly (≥ 60) Fit Patients With Poor Prognosis Acute Myeloid…
- Trial name
- NCT01301820
- Testing
- azacitidine, Lenalidomide
- Where
- France
- Volunteers
- 120 people
- Sponsor
- French Innovative Leukemia Organisation
Neoplasm, Metastasis
Extension Program for Bay 43-9006
The study was designed to allow for the continuation of treatment with Sorafenib as a single agent to those patients who participated in a previous Sorafenib study that had reached its designated end-date and who were, in the…
- Trial name
- NCT00657254
- Testing
- Nexavar (Sorafenib, BAY43-9006)
- Where
- 6 sites in United States, Belgium and 2 more
- Volunteers
- 9 people
- Sponsor
- Bayer
Gastric Cancer, Chemotherapy Effect
Comparative Study of Lobaplatin and Paclitaxel in Advanced Gastric Cancer Patients With D2 Surgery Combined With Hyperthermic Intraperitoneal Chemotherapy
This study is a prospective, randomized, comparative clinical trial conducted by Wuhan Union Hospital and aim to compare the therapeutic effects of Lobaplatin and Paclitaxel in advanced gastric cancer patients with D2 surgery…
- Conditions
- Gastric Cancer, Chemotherapy Effect, Surgery, Metastasis
- Trial name
- WUHIPEC01 (NCT04808466)
- Testing
- Paclitaxel, Lobaplatin
- Where
- China
- Volunteers
- 231 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Colorectal Cancer Liver Metastasis
Study Comparing Radio Frequency Ablation Plus Chemotherapy and Chemotherapy Alone in Patients With Unresectable CRLM
To date no prospective trials have been completed that demonstrated whether RFA is an effective adjunct to systemic chemotherapy (target therapy) with respect to advantages in overall survival compared with chemotherapy (target…
- Trial name
- NCT03127072
- Testing
- Radiofrequency Ablation (RFA), chemotherapy ± target therapy
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Fudan University
Pancreatic Ductal Adenocarcinoma (PDAC)
Expanded Access to PCNAT-01 for Patients With Resected Pancreatic Ductal Adenocarcinoma Following Surgical Resection and Adjuvant Therapy
This expanded access program provides a potential pathway for eligible patients with resected pancreatic ductal adenocarcinoma (PDAC) to receive PCNAT-01, an investigational, personalized tumor neoantigen peptide vaccine, outside…
- Trial name
- NCT07612930
- Testing
- PCNAT-01
- Sponsor
- Anda Biopharmaceutical Development (Shenzhen) Co., Ltd.
Cervical Cancer, Hysterectomy
Minimally Invasive Surgery Versus Open Radical Hysterectomy in Presumably Early Stage Cervical Cancer: a Retrospective Multicenter Non-inferiority Study Comparing Overall and Progression-free Survival.
The goal of this retrospective observational study with prospective follow-up is to compare the safety and treatment outcomes of radical laparoscopic hysterectomy (removal of the uterus with cervix) versus abdominal (open)…
- Trial name
- MOOSE (NCT07120529)
- Testing
- CT scan, Ultrasound scan (Transvaginal or Transabdominal), Gynecological examination
- Where
- 5 sites in Poland
- Volunteers
- 300 people
- Sponsor
- Medical University of Silesia
Uterine Cervical Neoplasms, Cervical Cancer by FIGO Stage 2018
A Radiomic MRI Predictive Model for Response to Concomitant Chemoradiotherapy in Locally Advanced Cervical Cancer
Cervical cancer is the fourth most common cancer in women worldwide, with approximately 604,000 new cases in 2020.Treatment for locally advanced cervical cancer is based on a combination of radiotherapy and chemotherapy.
- Trial name
- EPICOL-R (NCT07305727)
- Where
- France
- Volunteers
- 120 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Progression-Free Survival
Metformin for the Treatment of mCRC Patients Undergoing FOLFIRI Plus Target Therapy
To investigate progression-free survival (PFS) in patients with metastatic colorectal cancer treated with chemotherapy FOLFIRI monotherapy or chemotherapy FOLFIRI combined with Metformin
- Trial name
- NCT06826092
- Testing
- Metformin Pill, FOLFIRI plus target therapy only
- Where
- Taiwan
- Volunteers
- 110 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Colorectal Cancer (Diagnosis)
The Effectiveness of the mHealth Survivorship Program on Enhancing Health-related Quality of Life Among Colorectal Cancer Survivors
The goal of this clinical trial is to evaluate the effectiveness of the mHealth survivorship program in enhancing health-related quality of life among colorectal cancer survivors.
- Trial name
- NCT07158671
- Testing
- Intervention Group
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- The Nethersole School of Nursing
Hepatocellular Carcinoma
Different Genetic Features Associated With Hepatic Carcinogenesis
The purpose of this study is to identify different genetic features in hepatocellular carcinoma. It will assist in predicting individual risks of disease progression and would help to clarify pathophysiological mechanisms of HCC.
- Trial name
- NCT01247506
- Where
- Taiwan
- Volunteers
- 160 people
- Sponsor
- National Taiwan University Hospital