Clinical trials: Survival , Tumor
Head and Neck Cancer
TPF Plus Radiotherapy and Cetuximab to Avoid Total Laryngectomy in Patients With Larynx Cancer
A Phase II Trial With Radiotherapy Plus Cetuximab to Evaluate Specific Survival Free of Laryngectomy in Patients With Resectable and Locally Advanced Larynx Cancer, After Treatment With TPF Chemotherapy.
- Trial name
- NCT00765011
- Testing
- TPF, radiotherapy and cetuximab, H&N surgery
- Where
- 17 sites in Spain
- Volunteers
- 94 people
- Sponsor
- Grupo Español de Tratamiento de Tumores de Cabeza y Cuello
Breast Cancer
Bootcamp During Neoadjuvant Chemotherapy for Breast Cancer
This is a randomized, single-site pilot study incorporating one control group. This research involves an exercise group and a non-exercise group (control group).
- Trial name
- Bootcamp (NCT01411787)
- Testing
- Exercise
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of Texas Southwestern Medical Center
Pancreatic Cancer, Neoadjuvant Therapy
Long-term Survival Outcomes According to the Pathologic Response After Neoadjuvant Treatment in PDAC and the Fate of the Patients with Good CAP Grade
1. Neoadjuvant treatment (NAT) is increasingly used in managing pancreatic ductal adenocarcinoma (PDAC), necessitating dependable methods to evaluate tumor response. 2.
- Conditions
- Pancreatic Cancer, Neoadjuvant Therapy, Pathological Complete Response
- Trial name
- CAP with NAT (NCT06630481)
- Testing
- neoadjuvant therapy
- Volunteers
- 462 people
- Sponsor
- Seoul National University Hospital
Endometrium Cancer, Life Style
Effect of a Lifestyle Intervention on Nutritional Status and Prognosis of Endometrial Cancer Survivors
The objective of the present study is to implement and evaluate the effect of a counseling program to promote healthy eating and practice of physical activity in the nutritional status, quality of life and prognosis of women Type…
- Conditions
- Endometrium Cancer, Life Style, Obesity
- Trial name
- NCT03095664
- Testing
- Intervention group
- Where
- Brazil
- Volunteers
- 286 people
- Sponsor
- Brazilian National Cancer Institute
Liver Metastasis Colon Cancer
Improving Survival of COlorectal LIver Metastases by RFA-mediated Immunostimulation
To examine radio frequency ablation as a treatment supplement to stimulate immunogenicity and improve survival for patients undergoing curative-intent surgery for colorectal liver metastases.
- Trial name
- ISCOLIM (NCT04798898)
- Testing
- RFA (radiofrequency ablation)
- Where
- Denmark
- Volunteers
- 200 people
- Sponsor
- University of Aarhus
Cancer Survivorship
Taking Time to Connect: A Study of Programs for Hispanic Mothers Diagnosed With Cancer and Their Children
This NCI-funded randomized clinical trial (RCT) will test the short-term efficacy of Conexiones, a culturally adapted cancer education program designed to help Hispanic mothers diagnosed with cancer and their children to cope…
- Trial name
- TTTC (NCT03951454)
- Testing
- Conexiones, Taking Time
- Where
- 5 sites in United States
- Volunteers
- 43 people
- Sponsor
- New Mexico State University
Acute Myeloid Leukemia in Remission, Myelodysplastic Syndromes
Allogeneic Hematopoietic Cell Transplantation From HLA-matched Donor After Flu-Mel-PTCy Versus Flu-Mel-ATG Reduced-intensity Conditioning
The present project aims at comparing two conditioning regimens (FM-PTCy vs FM-ATG). The hypothesis is that one or the two regimens will lead to a 2-year cGRFS rate improvement from 30% (the cGRFS rate with FM without ATG/PTCy)…
- Conditions
- Acute Myeloid Leukemia in Remission, Myelodysplastic Syndromes, Chronic Myeloid Leukemia in Remission, Myeloproliferative Syndrome
- Trial name
- HLA (NCT03852407)
- Testing
- Thymoglobulin, Melphalan, Fludarabine
- Where
- 10 sites in Belgium
- Volunteers
- 114 people
- Sponsor
- University of Liege
Head and Neck Cancer, Survivorship
The HEART Study (Healthy Eating and Recovery Together)
Head and neck cancer survivors and their primary caregivers (N=25 dyads) will be enrolled to pilot test a nutrition support system with a care planning clinic visit and a caregiver mobile App.
- Conditions
- Head and Neck Cancer, Survivorship, Nutrition Aspect of Cancer
- Trial name
- NCT04552587
- Testing
- Heart APP
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Metastatic Pancreatic Cancer, Pancreatic Cancer
Study of Modified FOLFIRINOX in Advanced Pancreatic Cancer
The primary objective of this study was to determine the progression free survival in patients with metastatic pancreatic cancer and in patients with locally advanced unresectable non-metastatic pancreatic cancer treated with a…
- Trial name
- FOLFIRINOX (NCT01523457)
- Testing
- Folfirinox
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Yale University
Paraneoplastic Syndromes
CICLOPS Immune Checkpoint Inhibitors Neurotoxicity: Long-term Outcomes, Predictors, and Survival.
Immune-checkpoint inhibitors (ICIs) have radically changed the therapy of cancer in recent years. ICIs promote antitumor immune response inhibiting one of the following immune checkpoints: cytotoxic T-lymphocyte antigen-4…
- Trial name
- LOPF - NIRAES (NCT05942872)
- Testing
- This is a non-interventional study. We will collect clinical data exclusively, and will do so by reviewing all available patients clinical records.
- Where
- France
- Volunteers
- 90 people
- Sponsor
- Hospices Civils de Lyon
Prostate Cancer
Comparison of Docetaxel/Prednisone to Docetaxel/Prednisone in Combination With OGX-011 in Men With Prostate Cancer
This Phase 3 study has been designed to confirm that adding custirsen to standard first-line docetaxel/prednisone treatment can slow tumor progression and enhance survival outcomes compared to standard first-line…
- Trial name
- SYNERGY (NCT01188187)
- Testing
- Custirsen, Docetaxel, Prednisone
- Where
- 140 sites in United States, Belgium and 10 more
- Volunteers
- 1,022 people
- Sponsor
- Achieve Life Sciences
Stage 0a Bladder Cancer AJCC v8, Stage 0is Bladder Cancer AJCC v8
Quality of Life After Treatment for Bladder Cancer: The Bladder Cancer Survivorship Study
This study evaluates the effect of bladder cancer treatment on quality of life.
- Conditions
- Stage 0a Bladder Cancer AJCC v8, Stage 0is Bladder Cancer AJCC v8, Stage I Bladder Cancer AJCC v8, Stage II Bladder Cancer AJCC v8
- Trial name
- NCT06350734
- Testing
- Non-Interventional Study
- Where
- 3 sites in United States
- Volunteers
- 204 people
- Sponsor
- Mayo Clinic
Sarcoma
Study on Clinical Features, Treatment Mode and Survival of Sarcoma
The clinical data of all eligible patients who received chemotherapy, radiotherapy, targeted therapy, immunotherapy, interventional therapy and surgery in Henan Tumor Hospital from June 1, 2012 to May 30, 2022 were…
- Trial name
- NCT05453409
- Testing
- No intervention
- Where
- China
- Volunteers
- 6,000 people
- Sponsor
- Henan Cancer Hospital
Ovarian Cancer
AURELIA: A Study of Avastin (Bevacizumab) Added to Chemotherapy in Patients With Platinum-resistant Ovarian Cancer
This randomized, open-label, 2-arm study will evaluate the efficacy and safety of Avastin added to chemotherapy versus chemotherapy alone in patients with epithelial ovarian, fallopian tube or primary peritoneal cancer with…
- Trial name
- NCT00976911
- Testing
- Bevacizumab, liposomal doxorubicin, paclitaxel
- Where
- 117 sites in Belgium, Bosnia and Herzegovina and 12 more
- Volunteers
- 361 people
- Sponsor
- Hoffmann-La Roche
Breast Cancer, Breast Cancer Mortality
Influence of Lifestyle, Inflammatory Biomarkers, and Genetic Factors on Long-term Breast Cancer Prognosis
The MARIEplus study is a prospective cohort of breast cancer patients recruited into the MARIE (Mamma Carcinoma Risk factor InvEstigation) study, a population-based case-control study of breast cancer conducted in two German…
- Conditions
- Breast Cancer, Breast Cancer Mortality, Breast Cancer Survival, Postmenopausal Breast Cancer
- Trial name
- NCT03401034
- Volunteers
- 3,813 people
- Sponsor
- German Cancer Research Center
Acute Lymphoid Leukemia, Philadelphia Chromosome-Negative B-Cell Precursor
Sequential Chemotherapy and Blinatumomab to Improve MRD Response and Survival in Acute Lymphoblastic Leukemia
The present study aims at analyzing the response to treatment of adult patients homogeneously treated with supportive care, chemotherapy and blinatumomab.
- Trial name
- LAL2317 (NCT03367299)
- Testing
- Chemotherapy + Blinatumomab
- Where
- 62 sites in Italy
- Volunteers
- 149 people
- Sponsor
- Gruppo Italiano Malattie EMatologiche dell'Adulto
Gastric Cancer
Effect of Helicobacter Pylori Eradication After Subtotal Gastrectomy on Survival Rate of Gastric Cancer Patients: Retrospective Study
In this study, we will observe the long-term survival rate, overall mortality rate, gastric cancer specific mortality rate, and the incidence rate of metachronous cancer in patients who received subtotal gastrectomy, with or…
- Trial name
- NCT03978481
- Testing
- Helicobacter pylori eradication (combination therapy)
- Where
- South Korea
- Volunteers
- 3,700 people
- Sponsor
- Seoul National University Bundang Hospital
Nasopharyngeal Carcinoma
Tirelizumab Plus Surgery vs Surgery Alone for Recurrent Nasopharyngeal Carcinoma
Through open-label, single-center, randomised clinical trials, we intend to demonstrate that PD-1 treatment added to salvage surgery could further decrease the rate of disease progression and improve the survival outcome of…
- Trial name
- NCT05092217
- Testing
- Tirelizumab, salvage surgery
- Volunteers
- 80 people
- Sponsor
- Eye & ENT Hospital of Fudan University
Cancer Survivorship, Cardiovascular Disease
Routine LDL Exam For Cancer Survivors
This observational study will evaluate whether annual low-density lipoprotein cholesterol (LDL-C) testing is associated with improved cardiovascular preventive care and a lower risk of cardiovascular events among cancer…
- Trial name
- LDL Cancer (NCT07738250)
- Volunteers
- 1,294,726 people
- Sponsor
- Samsung Medical Center
Non-small Cell Lung Cancer
A Study of PC Sequential Pemetrexed Single Drug Maintenance Treatment for NSCLC and Related Predictive Biomarkers
PFS
- Trial name
- NCT01860508
- Testing
- pemetrexed /carboplatin
- Where
- China
- Volunteers
- 94 people
- Sponsor
- Fudan University
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