Clinical trials: Survival , Tumor
Smoking Cessation, Smoking
Precision Treatment to Promote Smoking Cessation and Survival in Oncology Patients
This study evaluates the feasibility and preliminary effects of precision tobacco treatment, compared to usual care, on promoting tobacco treatment in oncology patients and providers in the oncology care setting.
- Conditions
- Smoking Cessation, Smoking, Physician's Role
- Trial name
- PROMISE (NCT07166120)
- Testing
- Usual care, Precision treatment
- Where
- 2 sites in United States
- Volunteers
- 132 people
- Sponsor
- Washington University School of Medicine
Prostate Cancer
Digitally Captured Activity Data and PROs to Monitor Physical Function in Prostate Cancer Patients
Prospective observational research study to evaluate the role of wearable activity monitors to predict physical function decline among prostate cancer survivors receiving ADT.
- Trial name
- DigiPRO (NCT04575402)
- Testing
- Wearable Activity Monitor
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Cedars-Sinai Medical Center
Ovarian Carcinoma
Maintenance Treatment for Ovarian Carcinoma in Remission by an Antiangiogenic Treatment Strategy
Preclinical studies showed that metronomic chemotherapy can induce tumor regression secondary to apoptosis of the tumor blood vessels. This effect was increased by combining metronomic chemotherapy with anti-angiogenic drugs.
- Trial name
- NCT01175772
- Testing
- Cytophosphan, Celecoxib, Methotrexate
- Where
- Israel
- Volunteers
- 6 people
- Sponsor
- HaEmek Medical Center, Israel
Head and Neck Cancer, Survivorship
Big Data for Quality of Life in Head and Neck Cancer
Depending on disease stage, head and neck cancer (HNC) can be cured either with a single modality or with multimodal treatments, consisting of various combinations of surgery, radiotherapy, and chemotherapy.
- Conditions
- Head and Neck Cancer, Survivorship, Quality of Life
- Trial name
- BD4QoL (NCT05315570)
- Testing
- BD4QoL platform
- Where
- 3 sites in Italy, United Kingdom
- Volunteers
- 410 people
- Sponsor
- Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
Gallbladder Cancer
Palliative Biliary Stenting on the Quality of Life of Patients With Unresectable Carcinoma Gallbladder With Hiliar Block.
The purpose of the study is to determine whether palliative biliary stenting improves the quality of life, of gallblader cancer patients, who present with hilar block and obstructive jaundice.
- Trial name
- NCT00391183
- Testing
- Biliary stenting
- Where
- India
- Volunteers
- 60 people
- Sponsor
- All India Institute of Medical Sciences
Non-small Cell Lung Cancer
Effect of Time-of-Day (ToD) for Immunochemotherapy on PFS in NSCLC
This study aims to explore time-of-day of administration of immunochemotherapy on the efficacy for treatment naive advanced non-small cell lung cancer.
- Trial name
- LungTIME-C01 (NCT05549037)
- Testing
- Pembrolizumab, Sintilimab
- Where
- China
- Volunteers
- 210 people
- Sponsor
- Hunan Province Tumor Hospital
Pancreas Cancer, Pancreas Neoplasm
Survival, Quality of Life and Resectability in Locally Advanced Pancreatic Cancer
This study aims to assess overall survival, quality of life and resection rates in locally advanced pancreatic cancer
- Conditions
- Pancreas Cancer, Pancreas Neoplasm, Pancreas Disease, Pancreas Adenocarcinoma
- Trial name
- SQUARE (NCT05356039)
- Where
- Sweden
- Volunteers
- 300 people
- Sponsor
- Umeå University
Non-Small Cell Lung Cancer, Artificial Intelligence (AI) in Diagnosis
AI-Based Prediction of Stage and Survival in Non-Small Cell Lung Cancer: A Retrospective Study
This study aims to evaluate the role of artificial intelligence (AI) in predicting disease stage and survival in patients diagnosed with non-small cell lung cancer (NSCLC).
- Trial name
- NCT07068139
- Testing
- AI-Based Predictive Modeling
- Volunteers
- 156 people
- Sponsor
- Hilkat Fatih Elverdi
Prostate Cancer
RADAR Trial - Randomised Androgen Deprivation and Radiotherapy
The principal objectives of the RADAR trial is to address the hypotheses; 1) that 18 months androgen deprivation in conjunction with radiotherapy is superior to 6 months androgen deprivation prior to and during radiotherapy; 2)…
- Trial name
- NCT00193856
- Testing
- Leuprorelin Acetate, Zoledronic Acid, Conventional external beam therapy
- Where
- 24 sites in Australia, New Zealand
- Volunteers
- 1,071 people
- Sponsor
- Trans Tasman Radiation Oncology Group
Kidney Cancer
Pazopanib Versus Temsirolimus in Poor-Risk Clear-Cell Renal Cell Carcinoma (RCC)
The goal of this clinical research study is to compare pazopanib to temsirolimus in the treatment of advanced clear-cell renal cell carcinoma. The safety of each drug will also be studied.
- Trial name
- NCT01392183
- Testing
- Pazopanib, Temsirolimus, Quality of Life Assessment
- Where
- United States
- Volunteers
- 69 people
- Sponsor
- M.D. Anderson Cancer Center
Leukemia, Myeloid, Acute
Study of Vosaroxin and Cytarabine for the Treatment of Adults 60 Years of Age or Older With Previously Untreated AML
This is a pilot efficacy assessment clinical trial of vosaroxin and cytarabine for the treatment of adults 60 years of age or older with previously untreated acute myeloid leukemia.
- Trial name
- NCT02485353
- Testing
- Vosaroxin and Cytarabine
- Where
- 2 sites in United States
- Volunteers
- 2 people
- Sponsor
- Hamid Sayar
Ovarian Cancer Stage IIIC, Ovarian Cancer Stage IV
Reduction Of Cycles of neOadjuvant Chemotherapy for Advanced Epithelial Ovarian, Fallopian and Primary Peritoneal Cancer
Te hypothesized that two cycles of neoadjuvant chemotherapy followed by interval debulking surgery would improve survival in advanced epithelial ovarian, fallopian, and primary peritoneal cancer because reduction of one cycle of…
- Conditions
- Ovarian Cancer Stage IIIC, Ovarian Cancer Stage IV, Fallopian Tube Cancer, Peritoneal Cancer
- Trial name
- ROCOCO (NCT03693248)
- Testing
- Two cycles of neoadjuvant chemotherapy
- Where
- South Korea
- Volunteers
- 298 people
- Sponsor
- Seoul National University Hospital
Colorectal Cancer Metastatic
Second-line FOLFIRI + Panitumumab in Subjects With Wild Type RAS Metastatic Colorectal
To estimate progression-free-survival at 6 months in subjects treated in first-line with panitumumab and FOLFOX and with wild type RAS mCRC (metastatic colorectal cancer) confirmed in liquid biopsies before starting second line…
- Trial name
- BEYOND (NCT03751176)
- Testing
- Panitumumab, Irinotecan, Folinic acid
- Where
- 18 sites in Spain
- Volunteers
- 31 people
- Sponsor
- Grupo Espanol Multidisciplinario del Cancer Digestivo
Colorectal Cancer
An Observational Study of Avastin (Bevacizumab) in Combination With Xeloda (Capecitabine) And Oxaliplatin in Patients With Colorectal Cancer
This prospective observational study will evaluate the efficacy and safety of bevacizumab in combination with capecitabine and oxaliplatin as first-line treatment in participants with colorectal cancer.
- Trial name
- NCT01399190
- Testing
- Bevacizumab, Capecitabine, Oxaliplatin
- Where
- 9 sites in Slovakia
- Volunteers
- 68 people
- Sponsor
- Hoffmann-La Roche
Metastatic Breast Cancer, Response Monitoring
FDG-PET/CT vs. CT for Monitoring Metastatic Breast Cancer
Several studies have shown improved sensitivity of FDG-PET/CT compared with conventional imaging for diagnosing metastatic breast cancer in retrospective and smaller prospective studies.
- Trial name
- MONITOR-RCT (NCT06877949)
- Testing
- FDG-PET/CT, CE-CT
- Where
- 11 sites in Denmark, Germany and 1 more
- Volunteers
- 420 people
- Sponsor
- Odense University Hospital
Colon Cancer (Stage II &Amp;Amp; III)
RASi for Preventing Postoperative Recurrence of Stage II/III Colon Cancer
The goal of this retrospective cohort study is to learn about the long-term effects of renin-angiotensin system inhibitors (RASi) in preventing patients with hypertension and stage II/III colon cancer from recurrence and…
- Trial name
- RAIPC (NCT07012538)
- Testing
- Renin-angiotensin system inhibitors (RASi), No renin-angiotensin system inhibitors (No RASi)
- Where
- China
- Volunteers
- 2,640 people
- Sponsor
- Fudan University
Breast Cancer
Venlafaxine for Hot Flashes After Breast Cancer
The purpose of this study is to evaluate Venlafaxine as a treatment option for hot flashes in breast cancer survivors. The goals of this study are to assess the effectiveness and toxicity of venlafaxine hydrochloride and identify…
- Trial name
- NCT00198250
- Testing
- venlafaxine
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Indiana University
HCC - Hepatocellular Carcinoma, Colorectal Cancer Metastatic
ctDNA Monitoring in Patients With HCC and mCRC
"Liquid biopsy" is a collective term that refers to the analysis of cancer-derived biomarkers isolated from the biological fluids of cancer patients.
- Trial name
- NCT07001085
- Testing
- Tumor Tissue Collection and NGS, Blood Collection for Plasma ctDNA, ctDNA Mutation Analysis via ddPCR
- Where
- Poland
- Volunteers
- 300 people
- Sponsor
- Medical University of Warsaw
Cancer, Metastases
Analysis of Tokuhashi Score
70% of all cancer patients develop some form of visceral (internal organs) or skeletal metastases (spread of disease). Approximately one third of cancer patients develop metastases to the spinal column.
- Trial name
- NCT01210508
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- State University of New York - Upstate Medical University
Cancer, Survivorship
On-Trac: An Online Intervention for Cancer Survivors Managing Anxiety
This study is evaluating On-Trac (Online Training After Cancer), an online educational intervention to teach adult cancer survivors strategies to address anxiety based on Cognitive-Behavioral Therapy (CBT) and Acceptance…
- Conditions
- Cancer, Survivorship, Anxiety
- Trial name
- On-Trac (NCT07305740)
- Testing
- ON-TRAC Education session, ON-TRAC Coaching
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Dana-Farber Cancer Institute
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