Clinical trials: Survival , Tumor
Colonic Cancer, Unresectable Metastasis Originating in Colonic Cancer
Resection vs no Resection of the Primary in Colorectal Cancer With Unresectable Metastases
Main outcome: Assess the impact of cancer-related survival at 2 years in patients with unresectable metastatic colorectal cancer treated with chemotherapy alone versus surgery followed by chemotherapy. To assess overall survival.
- Trial name
- CCRe-IV (NCT02015923)
- Testing
- Colonic resection, Chemotherapy- scheme
- Where
- 22 sites in Spain
- Volunteers
- 107 people
- Sponsor
- Hospital Universitari de Bellvitge
Colorectal Cancer in Patients Under 50 Years of Age, Colorectal Cancer
Colorectal Cancer in Young Adults: Study of Incidence, Survival, and Prognostic Factors in Tarragona, Spain
We conducted an observational, descriptive, longitudinal and retrospective study of 59 patients under 50 years of age diagnosed with CRC in the province of Tarragona, between 2019 and 2024.
- Trial name
- CCR50 (NCT07026955)
- Testing
- colorectal cancer in patients over 50 years of age
- Where
- Spain
- Volunteers
- 59 people
- Sponsor
- HJ23
Lung Cancer Non-Small Cell Cancer (NSCLC)
Real-World Immuno-Radiotherapy for Advanced NSCLC
The optimal combination strategy for radiotherapy combined with immunotherapy (iRT) in advanced non-small-cell lung cancer (NSCLC) remains unclear, and there is a lack of real-world data to validate its efficacy.
- Trial name
- OCEANUS (NCT06747026)
- Testing
- initial Sequential iRT, initial Concurrent iRT, RT with maintenance of ICI
- Where
- Hong Kong
- Volunteers
- 338 people
- Sponsor
- Fengming Kong
The Aim of This Study is to Determine the Influence of BMI and Lymph Node Status on OS in CRC Patients in the Long Term
BMI and Lymph Node Count in Colorectal Cancer
Background and aim: Colorectal Cancer (CRC) is one of the most frequent cancer entities in the western world. It is known that obesity is one of the major risk factors for CRC.
- Trial name
- NCT06334926
- Testing
- no intervention, retrospective data analysis
- Where
- Austria
- Volunteers
- 1,192 people
- Sponsor
- Klinikum Floridsdorf
Cancer
Real-World Study of Young Patients With Solid Tumors in China
To evaluate organ preservation rates, fertility preservation, and long-term quality of life after treatment among young patients.
- Trial name
- NCT07708935
- Testing
- Ages 18-40
- Where
- China
- Volunteers
- 12,000 people
- Sponsor
- Fudan University
Breast Cancer
A Phase III Randomized Trial of Metformin vs Placebo in Early Stage Breast Cancer
This study is looking at whether Metformin, an agent that is commonly used to treat diabetes, can decrease or affect the ability of breast cancer cells to grow and whether Metformin will work with other therapies to keep cancer…
- Trial name
- NCT01101438
- Testing
- metformin hydrochloride
- Where
- 344 sites in United States, Canada and 2 more
- Volunteers
- 3,649 people
- Sponsor
- Canadian Cancer Trials Group
Non-Small Cell Lung Cancer
Study of Etoposide, Cisplatin, and Radiotherapy Versus Paclitaxel, Carboplatin and Radiotherapy to Treat Non-Small Cell Lung Cancer
Cisplatin-based combination chemotherapy given concurrently with radiotherapy is the standard of care for patients with inoperable stage III NSCLC.
- Trial name
- NCT01494558
- Testing
- Chemoradiotherapy Regimen between PC and PE
- Volunteers
- 200 people
- Sponsor
- Chinese Academy of Medical Sciences
Cancer, Caregiving Stress
Building Empowerment and Coping Outcomes for CaNcer Patients, Survivors and Their Caregivers
Cancer has a psychological, emotional and social impact beyond a patient's physical health. This study examines three new online peer mental-wellness support program for cancer patients, survivors or their caregivers.
- Conditions
- Cancer, Caregiving Stress, Caregiver Burnout, Survivorship
- Trial name
- BEACON (NCT06353178)
- Testing
- Cancer Connect Program
- Where
- United States
- Volunteers
- 133 people, healthy volunteers welcome
- Sponsor
- Color Health, Inc.
Colorectal Cancer, Survivorship
Colorectal Cancer Survivor Symptom Management
Objective: The aim of this study was to examine the effects of nursing interventions based on the symptom management model on symptom management, fear of recurrence, and quality of life in colorectal cancer survivors.
- Trial name
- CRCaSSM (NCT05876338)
- Testing
- CRCaSSM
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Akdeniz University
Long-term Effects of Cancer Treatment
A Long-term Survival Analysis of Different Surgical Method in Early Hepatocellular Carcinoma
The investigators established three prospective cohorts of patients with BCLC stage 0-A HCC, based on different surgical approaches (open, laparoscopic and robotic).
- Trial name
- NCT05117047
- Testing
- liver resection
- Where
- China
- Volunteers
- 369 people
- Sponsor
- Chen Xiaoping
Pancreatic Cancer
Use of Epidurals Intraoperatively for Patients Undergoing Pancreas Resection
The purpose of this study is to see if there is a difference in complications in patients who have an epidural started earlier (during their surgery) and used as part of the anesthetic in addition to using it for post operative…
- Trial name
- NCT03434678
- Testing
- Propofol+ Rocuronium+ Fentanyl 2 mcg/kg+ Inhalational Agent, Bupivacaine 0.125% + Fentanyl 5 mcg/ml, Propofol+ Rocuronium+ Fentanyl + Inhalational, Open Pancreaticoduodenectomy
- Where
- 3 sites in United States
- Volunteers
- 133 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Gastric Cancer
Erbitux in Combination With Xeloda and Cisplatin in Advanced Esophago-gastric Cancer
The primary objective of this study is to demonstrate that addition of cetuximab to 1st-line treatment with capecitabine (Xeloda, X) and cisplatin (P) [XP] chemotherapy regimen has a clinically relevant benefit for subjects with…
- Trial name
- EXPAND (NCT00678535)
- Testing
- Cetuximab, Capecitabine, Cisplatin
- Where
- 130 sites in Argentina, Australia and 23 more
- Volunteers
- 904 people
- Sponsor
- Merck KGaA, Darmstadt, Germany
Lymphoma
A Resilience-Based Approach to Improve Long-term Quality of Life in Post-treatment Lymphoma Survivorship
The goal of this trial is to learn if a resilience intervention can lead to improvements in lymphoma survivors' quality of life.
- Trial name
- NCT07013435
- Testing
- Health Education Program, SMART3RP-Lymphoma
- Where
- 3 sites in United States
- Volunteers
- 254 people
- Sponsor
- Massachusetts General Hospital
Colorectal Cancer
Effect of Stent Placement on Short Term Survival of Left Sided Obstructive Colorectal Cancers
The aim of this observational study is to determine effect of stent placement on survival results in first three years in a patient who applied to the emergency department with obstruction due to colorectal cancer.
- Trial name
- NCT06437691
- Testing
- Self-Expandable Metallic Stent Placement
- Volunteers
- 65 people
- Sponsor
- Yasir Musa Kesgin, MD
Castration-Resistant Prostatic Cancer
An External Control Arm Study Comparing Survival Among Metastatic Castration-Resistant Prostate Cancer (mCRPC) Patients Treated With 177Lu-PSMA-617 vs Androgen Receptor Pathway Inhibitor (ARPI) Switch in Routine Care
The aim of this study is to assess the effectiveness of 177Lu-PSMA-617 (lutetium (177Lu) vipivotide tetraxetan) on survival in patients randomized to receive treatment following progression on one ARPI from the PSMAfore trial…
- Trial name
- NCT07843758
- Where
- Switzerland
- Volunteers
- 1,525 people
- Sponsor
- Novartis Pharmaceuticals
Esophageal Cancer, Nutrition Aspect of Cancer
Assessing Timing of Enteral Feeding Support in Esophageal Cancer Patients on Muscle functTion and Survival
The surgical stress of an esophagectomy causes a detrimental impact on the physiological response of the body. In this perspective, one could question whether the current feeding regimens of starting early nutritional support at…
- Conditions
- Esophageal Cancer, Nutrition Aspect of Cancer, Postoperative Complications, Muscle Weakness
- Trial name
- EFECTS (NCT03676478)
- Testing
- delayed start enteral support @ POD5
- Where
- Belgium
- Volunteers
- 239 people
- Sponsor
- University Hospital, Gasthuisberg
Spinal Metastases, Non-Small-Cell Lung Cancer Metastatic
Verification of Novel Survival Prediction Algorithm for Patients With NSCLC Spinal Metastasis
The purpose of this study is to learn whether our own made predictive algorithm can be used as a clinical practical decision support for patients with NSCLC spinal metastasis.
- Trial name
- NCT03363685
- Where
- China
- Volunteers
- 140 people
- Sponsor
- Ruijin Hospital
Glioma of Brain
Neuropsychological and Oncological Outcomes in Grade 2 or 3 Glioma Patients Undergoing Postoperative Modern Radiotherapy
Background: Infiltrative low grade gliomas (LGGs) are the most common primary central nervous system malignancies excluding the highest grade glioma, glioblastoma multiforme.
- Trial name
- NCT03534050
- Testing
- postoperative adjuvant RT
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- Chang Gung Memorial Hospital
Breast Cancer, Breast Adenocarcinoma
A Prospective, Multicenter Registry to Observe the Treatment Patterns, Clinical Outcomes, and Decision-Making in Patients With Early Breast Cancer Eligible for EndoPredict® Testing
The study is planned to observe and document the therapeutic decision-making process, treatment protocols, and clinical outcomes in patients with luminal breast cancer, whether they have undergone EndoPredict® testing or not
- Trial name
- PRELUDE (NCT07389408)
- Where
- 13 sites in Greece
- Volunteers
- 2,000 people
- Sponsor
- National and Kapodistrian University of Athens
Lymphoma, Large B-Cell, Diffuse
The Impact of Rituximab in Patients With Primary Breast Diffuse Large B Cell Lymphoma (DLBCL)
The purpose of this study is to investigate the impact of rituximab in primary breast DLBCL using a matched pair analysis following strict matching criteria in patients with primary breast and nodal DLBCL treated with rituximab…
- Trial name
- NCT01266668
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Chonbuk National University Hospital
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