Clinical trials: Survival Outcomes
Osteoarthritis of Hip, Traumatic Arthritis of Hip
Long-Term Multi-center Evaluation of E-Poly and Regenerex
There are two distinct aims of this study: 1. This prospective study is designed to document the long-term (10-year) radiographic and clinical outcomes of a new type of highly cross-linked polyethylene liner which contains…
- Trial name
- NCT00545285
- Testing
- Total Hip Arthroplasty
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- Massachusetts General Hospital
Pancreatic Cancer, Neoadjuvant Chemotherapy
Multimodal Therapy Impact on Pancreatic Cancer Survival
The goal of this retrospective cohort study is to analyze change of treatment strategies affect the survival outcomes in patients of pancreatic cancer who received curative-intent treatment.
- Conditions
- Pancreatic Cancer, Neoadjuvant Chemotherapy, Pancreatectomy
- Trial name
- MMTIPS (NCT06938906)
- Where
- Taiwan
- Volunteers
- 405 people
- Sponsor
- National Cheng Kung University
Hematopoietic and Lymphoid System Neoplasm, Malignant Solid Neoplasm
Group Curriculum for Improving Survivorship Outcomes in Adolescent and Young Adult Cancer Survivors
This clinical trial studies the effectiveness of a group curriculum in improving survivorship outcomes in adolescent and young adult (AYA) cancer survivors.
- Trial name
- NCT05584449
- Testing
- Counseling, Discussion, Informational Intervention
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Mayo Clinic
Breast Cancer
Healthy Eating and Active Lifestyle (HEAL): Breast Cancer Program Outcomes
The goal of this single-group prospective study is to examine the impact of the Healthy Eating and Active Lifestyle (HEAL) Breast Cancer program on participants' perceived stress, biometrics, basic labs, lifestyle behaviors…
- Trial name
- HEAL BC (NCT06078761)
- Testing
- Healthy Eating Active Lifestyle (HEAL) Program
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- AdventHealth
Homelessness, Health Behavior
Peer Support for Homelessness in the Emergency Department
Peer support workers with lived experience of homelessness will provide advocacy, supportive counselling, assistance with navigating the system, and role-modeling for people experiencing homelessness in emergency departments in…
- Conditions
- Homelessness, Health Behavior, Health Care Utilization, Health Care Seeking Behavior
- Trial name
- NCT04012697
- Testing
- Peer Support
- Where
- Canada
- Volunteers
- 19 people
- Sponsor
- McMaster University
HIV Infections, AIDS-Related Opportunistic Infections
When to Start Anti-HIV Drugs in Patients With Opportunistic Infections
The purpose of this study is to evaluate the effect of starting anti-HIV drugs in HIV infected patients who are being treated for opportunistic infections (OIs).
- Trial name
- NCT00055120
- Testing
- Emtricitabine/tenofovir disoproxil fumarate, Lopinavir/ritonavir, Stavudine
- Where
- 45 sites in United States, Puerto Rico and 1 more
- Volunteers
- 283 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Sarcoma, Sarcoma of Bone and Connective Tissue
Exercise Rehabilitation to Improve Long-term Outcomes in Sarcoma Survivors.
People who have had a sarcoma removed from the leg often live with weak muscles, stiff joints, and trouble walking. These problems can last for years. Formal medical follow-up usually ends about five years after treatment.
- Conditions
- Sarcoma, Sarcoma of Bone and Connective Tissue, Sarcoma of Soft Tissue, Sarcoma of Bone
- Trial name
- NCT07893041
- Testing
- Supervised Exercise Rehabilitation Program
- Volunteers
- 25 people
- Sponsor
- Curtin University
Lung Non-Small Cell Carcinoma, Stage I Colorectal Cancer AJCC v8
Self-Management Survivorship Care in Stage I-III Non-small Cell Lung Cancer or Colorectal Cancer
This phase III trial studies how well a telehealth self-management program works in improving survivorship care and outcomes in stage I-III non-small cell lung cancer or colorectal cancer survivors.
- Conditions
- Lung Non-Small Cell Carcinoma, Stage I Colorectal Cancer AJCC v8, Stage I Lung Cancer AJCC v8, Stage IA1 Lung Cancer AJCC v8
- Trial name
- NCT04428905
- Testing
- Quality-of-Life Assessment, Questionnaire Administration, Survivorship Care Plan
- Where
- United States
- Volunteers
- 403 people
- Sponsor
- City of Hope Medical Center
Bladder Cancer, Bladder Cancer Stage I
The Impact of Neoadjuvant Chemotherapy on Survival Outcomes in Patients With Variant Histologies Bladder Cancer Who Underwent Radical Cystectomy
The World Health Organization 2016 bladder tumor classification reported that the diagnosis of variant histology has increased from 6% to 33% in the last 2 decades, and there is an increasing interest in investigating the effects…
- Conditions
- Bladder Cancer, Bladder Cancer Stage I, Bladder Cancer Stage II
- Trial name
- NCT06358599
- Testing
- Cisplatin
- Where
- Turkey (Türkiye)
- Volunteers
- 221 people
- Sponsor
- Ankara Etlik City Hospital
Infant, Newborn, Infant, Small for Gestational Age
Hydrocortisone for BPD
The Hydrocortisone and Extubation study will test the safety and efficacy of a 10 day course of hydrocortisone for infants who are less than 30 weeks estimated gestational age and who are intubated at 14-28 days of life.
- Conditions
- Infant, Newborn, Infant, Small for Gestational Age, Infant, Very Low Birth Weight, Infant, Premature
- Trial name
- NCT01353313
- Testing
- Hydrocortisone
- Where
- 20 sites in United States
- Volunteers
- 800 people
- Sponsor
- NICHD Neonatal Research Network
Quality of Life, Cancer
Evaluating Cancer Survivorship Care Models
The Evaluating Cancer Survivorship Care Models project is an innovative 3-year study that is collecting data to help understand how to best deliver follow-up care to cancer survivors.
- Trial name
- NCT02362750
- Testing
- Consultative Specialized Survivorship Clinic (CSSC), Longitudinal Specialized Survivorship Clinic (LSSC), Oncology Embedded Survivorship Clinic (OESC)
- Where
- United States
- Volunteers
- 991 people
- Sponsor
- George Washington University
Biliary Tract Cancer, Portal Vein Embolization
Effect of PVE on Surgical Outcomes and Long-term Survival in Perihilar Cholangiocarcinoma
Portal vein embolization is often recommended to reduce the risk of postoperative liver failure and mortality. In this retrospective cohort study, researchers investigated the effect of portal vein embolization in patients with…
- Trial name
- NCT06222619
- Testing
- Potal vein embilization
- Where
- South Korea
- Volunteers
- 136 people
- Sponsor
- Seoul National University Hospital
Neuroendocrine Carcinoma of Lung, Neuroendocrine Carcinoma of Thymus
CompArative Analysis Between, Thymic, pulmonaRy and Pancreatic Well Differentiated High Grade Neuroendocrine Tumors
The study involves the enrollment of 34 patients diagnosed with advanced thymic, pulmonary and duodeno-pancreatic well-differentiated high grade neuroendocrine tumors (Ki-67 > 20%).
- Trial name
- LINEAR (NCT07429851)
- Where
- Italy
- Volunteers
- 34 people
- Sponsor
- European Institute of Oncology
Hepatocellular Carcinoma
Comparison of Two Solvents Used With Chemotherapy Agent for Transarterial Chemoembolization of Hepatocellular Carcinoma
TACE is considered the standard treatment for unresectable HCC and is widely used as a palliative treatment. However there is no consensus of the protocol of TACE.One of the variation is does the stability of the suspension by…
- Trial name
- NCT01259414
- Testing
- Solvent with specific gravity less than lipiodol, Solvent with specific gravity equivalent to lipiodol
- Where
- China
- Volunteers
- 812 people
- Sponsor
- Sun Yat-sen University
Muscle-Invasive Bladder Carcinoma, Chemotherapy Effect
Role of NAC in cT0 Muscle-invasive Bladder Cancer After Maximal TURBt
This prospective randomized controlled trial (RCT) is designed to provide high level evidence describing the non-inferiority of radical cystectomy (RC) alone versus neoadjuvant chemotherapy (NAC) plus RC on survival outcomes of…
- Conditions
- Muscle-Invasive Bladder Carcinoma, Chemotherapy Effect, Surgery
- Trial name
- NCT05776758
- Testing
- cisplatin based neoadjuvant chemotherapy, Radical cystectomy alone
- Where
- Italy
- Volunteers
- 236 people
- Sponsor
- Regina Elena Cancer Institute
Breast Cancer
A Real-world Study of Indian Patients With Advanced Breast Cancer Treated With Ribociclib
The aim of this study was to assess the effectiveness, safety, and tolerability of ribociclib in Indian women with hormone receptor positive (HR+) and human epidermal growth factor receptor 2 negative (HER2-) advanced breast…
- Trial name
- RESONATE (NCT07363434)
- Where
- United States
- Volunteers
- 335 people
- Sponsor
- Novartis Pharmaceuticals
Cardiac Arrest (CA), Post Cardiac Arrest Syndrome
Survival After Cardiac Arrest: How New Treatment Guidelines Changed Patient Outcomes.
The goal of this retrospective observational cohort study is to evaluate whether the progressive implementation of updated post-cardiac arrest care guidelines has improved survival and neurological recovery in adult patients…
- Trial name
- RetroAC (NCT07649889)
- Testing
- post-resuscitation care
- Where
- Italy
- Volunteers
- 630 people
- Sponsor
- Azienda Sanitaria Universitaria Integrata del Trentino
Acute Abdomen
Upper Gastrointestinal Perforations: a Nationwide Registry-based Study
The primary aim of this project is to increase the knowledge about how perforations in the esophagus, stomach and small intestine are treated on a national level.
- Trial name
- NCT06154603
- Testing
- Surgical treatment type
- Where
- Sweden
- Volunteers
- 2,000 people
- Sponsor
- Region Stockholm
Psychosocial Distress, Cancer
Addressing Cancer-Related Distress Through Survivorship Care in Community Oncology
The goal of this study is to understand whether providing a structured survivorship care visit at the beginning of cancer treatment is associated with changes in distress and quality of life in adults with cancer receiving…
- Trial name
- NCT07673731
- Testing
- Structured Survivorship Visit
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Ellis Medicine
Gastrointestinal Disease
Long-term Outcomes of Duodenal Adenocarcinoma From a Large Cohort
The investigators will conducted a hospital-based cohort study in our 15-year experience with DA aimed at investigating the long-term outcomes of the patients with DA, along with analyzing the impact of the tumor characteristics…
- Trial name
- NCT06443086
- Testing
- Radical operation and perioperative therapy
- Volunteers
- 400 people
- Sponsor
- Nanfang Hospital, Southern Medical University