Clinical trials: Survival Rate
Edentulous
A Clinical Evaluation of NobelProcera Implant Bar Overdenture
AN OPEN 5-YEAR PROSPECTIVE, CLINICAL MULTI-CENTER STUDY on NobelProcera Implant Bar Titanium with Locator attachment and related Overdenture on 4 NobelReplace implants with conical connection (CC) in the mandible/maxilla.
- Trial name
- NCT01720420
- Testing
- NobelReplace CC, NobelProcera Implant Bar
- Where
- 7 sites in Germany, Italy
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Nobel Biocare
Metastatic Castration-resistant Prostate Cancer
The Study of 177Lu-TLX591 Plus SOC Versus SOC Alone in Patients With mCRPC (ProstACT Global)
The purpose of this study is to evaluate the efficacy and safety of 177Lu-TLX591 in patients with metastatic castration-resistant prostate cancer who have progressed following treatment with Androgen Receptor Pathway Inhibitor…
- Trial name
- NCT06520345
- Testing
- 177Lu-TLX591, Enzalutamide, Abiraterone
- Where
- 33 sites in United States, Australia and 4 more
- Volunteers
- 520 people
- Sponsor
- Telix Pharmaceuticals (Innovations) Pty Limited
Advanced Prostate Cancer
A Long-term Observational Study Cohort in Patients With Advanced Prostate Cancer
The purpose of the protocol is to assess the rate of castration resistance, disease progression and overall survival over a 3-year period post-androgen deprivation therapy (ADT) induction in a study cohort of patients with…
- Trial name
- TRIPTOCARE LT (NCT01383863)
- Where
- 35 sites in Denmark, France and 5 more
- Volunteers
- 180 people
- Sponsor
- Ipsen
Deafness, Hearing Loss
Long-term Stability and Survival Rates of a Novel Oticon Medical Bone Conduction Device Implant
The overall aim of the study is to investigate the Ponto wide implant considering; initial implant stability, stability over time, skin reaction and long term success when loaded at 3 weeks post surgery.
- Conditions
- Deafness, Hearing Loss, Hearing Loss, Conductive, Hearing Disorders
- Trial name
- NCT01738490
- Testing
- Bone anchored hearing implant
- Where
- Netherlands
- Volunteers
- 59 people
- Sponsor
- Oticon Medical
Dental Caries
Survival Rate and Cost-effectiveness of Conventional vs ART Restorations in a School Setting
This study will investigate the performance and cost-effectiveness of glass-ionomer restorations placed in school children in an outreach setting in rural areas in South Africa over a 2-year period, when placed using either ART…
- Trial name
- NCT05766696
- Testing
- Atraumatic Restorative Treatment (ART), Conventional Cavity Preparation
- Where
- South Africa
- Volunteers
- 200 people
- Sponsor
- DMG Dental Material Gesellschaft mbH
Progress-free Survival, Overall Response Rate
Study for HER2-Overexpressed MBC Patients Treated by Cipterbin® Plus vinorelbinE
Breast cancer is the most common malignant disease and the most frequent causes of cancer mortality in females worldwide. The situation is same as the world in China.
- Conditions
- Progress-free Survival, Overall Response Rate, Adverse Events
- Trial name
- HOPES (NCT01291667)
- Volunteers
- 330 people
- Sponsor
- Shanghai CP Guojian Pharmaceutical Co., Ltd.
Recurrent/Metastatic Squamous Cell Carcinoma of the Head and Neck (HNSCC)
Pepinemab in Combination With Pembrolizumab in Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck
The purpose of the study is to evaluate the safety and tolerability of pepinemab in combination with pembrolizumab as first-line treatment and determine a recommended Phase 2 dose (RP2D) in patients with recurrent or metastatic…
- Trial name
- KEYNOTE-B84 (NCT04815720)
- Testing
- pepinemab + pembrolizumab
- Where
- 15 sites in United States
- Volunteers
- 49 people
- Sponsor
- Vaccinex Inc.
Dental Implants
Study Evaluating the Performance and Safety in the Medium and Long Term of Global D ZygoFixU System
Global D has developed an zygomatic implant prosthetic system (ZygoFixU range): zygomatic implants, prosthetic parts and associated instruments.
- Trial name
- NCT06960460
- Testing
- Dental implant surgery with ZygoFixU implants
- Where
- 3 sites in France, Italy
- Volunteers
- 99 people
- Sponsor
- Global D
Surgical Operation With Implant of Artificial Internal Device
A Non-Interventional Study to Document the Use of Straumann BLX Implants in Daily Dental Practice
Prospective, multi-center, non-interventional observation to document the success and survival rates of Straumann BLX Implants used for tooth replacement in cleared indications up to 1 year after implant placement
- Trial name
- BLX_NIS (NCT03613077)
- Testing
- surgical placement of an endosteal implant
- Where
- Germany
- Volunteers
- 153 people
- Sponsor
- Institut Straumann AG
Advanced Malignancy, Advanced Solid Cancers
ADCX-020 for the Treatment of Patients With Locally Advanced or Metastatic Cancers
The purpose of this first-in-human study is to explore the safety, pharmacokinetics and effects of the study drug ADCX-020 in patients with advanced and metastatic solid tumors.
- Conditions
- Advanced Malignancy, Advanced Solid Cancers, Metastatic Solid Tumors
- Trial name
- NCT07238075
- Testing
- ADCX-020
- Where
- 9 sites in Australia, Spain
- Volunteers
- 290 people
- Sponsor
- Adcytherix SAS
Dental Implants
Study Evaluating the Performance and Safety in the Medium and Long Term of Global D Implant-prosthetic Systems
This study is set up within the framework of the European Union regulation 2017/745 on medical devices. Its objective is to confirm the performance and safety in the medium and long term of implant-prosthetic systems including…
- Trial name
- NCT04960904
- Testing
- Dental implant surgery with implants
- Where
- 2 sites in France, Greece
- Volunteers
- 514 people
- Sponsor
- Global D