Clinical trials: Survivor of Childhood Cancer
Hypopituitarism, Hypogonadism
Detection and Treatment of Endocrine Abnormalities in Childhood Cancer Survivors and Hematopoietic Stem Cell Transplant Recipients
This study will determine the prevalence of endocrine-related side effects in children who have been treated for cancer and establish a database and registry organized according to cancer diagnosis, treatments and endocrine side…
- Conditions
- Hypopituitarism, Hypogonadism, Thyroid Dysfunction, Bone Diseases, Metabolic
- Trial name
- NCT00504218
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Ototoxicity, Drug-Induced, Ototoxicity, Radiation-Induced
Analysis of Risk Factors for Hearing Loss in Survivors of Cancer Occurred During Childhood, Adolescence or Young Adulthood
This study is aimed at people treated for cancer before the age of 25, who have been followed for at least 5 years, and who are now aged between 18 and 50. It is a prospective, multicenter, non-randomized study.
- Conditions
- Ototoxicity, Drug-Induced, Ototoxicity, Radiation-Induced, Pediatric Cancer
- Trial name
- RISP-OTOTOX (NCT06957132)
- Testing
- Audiogram
- Where
- 3 sites in France
- Volunteers
- 500 people
- Sponsor
- Gustave Roussy, Cancer Campus, Grand Paris
Cancer Childhood
Patient Navigation for Improving Transition Success Among Multiply Disadvantaged Young Adult Survivors of Childhood Cancer
The goal of this clinical trial is to improve the successful healthcare transition from pediatric to adult-focused care for childhood cancer survivors. The main questions it aims to answer are Receipt of the intervention (vs.
- Trial name
- NCT07630831
- Testing
- Navigation, Control
- Where
- United States
- Volunteers
- 190 people
- Sponsor
- Children's Hospital Los Angeles
Cancer, Leukemia
Lactation Outcomes Among Survivors of Pediatric Cancer
While the majority of women in the general population can breastfeed successfully, the investigators have limited knowledge about the correlates and sequelae of lactation success among women treated for pediatric malignancies.
- Trial name
- NCT02399956
- Testing
- Survey
- Where
- United States
- Volunteers
- 471 people
- Sponsor
- St. Jude Children's Research Hospital
Childhood Cancers
Cardiovascular Function in Adult Survivors of Childhood Malignancies
Anthracyclines have been used commonly to treat children with solid tumours and haematological malignancies and have led to their increased survival. Nonetheless, anthracycline has the side effect of cardiotoxicity.
- Trial name
- NCT01415999
- Where
- China
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Childhood Osteosarcoma
The Impact of Cancer on the Physical and Psychosocial Well-being Among Childhood Osteosarcoma Survivors
The aim of the study is to examine the impact of cancer and treatment-related effects on the physical and psychosocial well-being and quality of life among Hong Kong Chinese survivors of childhood osteosarcoma.
- Trial name
- NCT03298971
- Testing
- Questionnaires
- Where
- Hong Kong
- Volunteers
- 240 people
- Sponsor
- The University of Hong Kong
Hypertension
Assessing Blood Pressure Remotely in Childhood Cancer Survivors
Second malignant neoplasms and cardiac late effects are primary drivers of serious non-recurrence morbidity and mortality in long term childhood cancer survivors.
- Trial name
- NCT02476162
- Testing
- iHealth Wireless Blood Pressure Monitor
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- St. Jude Children's Research Hospital
Hematopoietic and Lymphoid Cell Neoplasm, Malignant Solid Neoplasm
Testing Counseling and Mobile Health Interventions to Improve Physical Activity and Diet Quality in Survivors of Childhood Cancer
This clinical trial evaluates several behavioral interventions for the improvement of physical activity in cancer patients. Childhood and adolescent/young adult cancer survivors have been reported to have poor diet quality and…
- Trial name
- SALSA (NCT05075759)
- Testing
- Behavioral Intervention, Survey Administration, Interview
- Where
- 2 sites in United States
- Volunteers
- 374 people
- Sponsor
- Fred Hutchinson Cancer Center
Survivors of Childhood Cancer, Acute Lymphoblastic Leukemia, Childhood
Feasibility and Acceptability of Remote Saliva Collection
The purpose of this study is to evaluate the practicality and acceptability of collecting biological samples and health information from childhood survivors of acute lymphoblastic leukemia (ALL) and their siblings.
- Trial name
- NCT07884474
- Testing
- Salivary Cortisol Collection, Blood Biomarker Collection, Hair Cortisol Collection
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- St. Jude Children's Research Hospital
Pediatric Cancer
LIFE Cancer Survivorship Database for Pediatric Cancer
The purpose of this study is to develop a mechanism for utilizing the comprehensive clinical database of childhood cancer survivors at Childrens Hospital Los Angeles (CHLA) for research purposes.
- Trial name
- NCT01518400
- Where
- United States
- Volunteers
- 5,000 people
- Sponsor
- Children's Hospital Los Angeles
Pediatric Cancer
ATOMIC Mobile App to Increase Physical Activity (PA) Levels in Survivors of Childhood Cancer
Development and Usability Testing of the ATOMIC Mobile App to Increase Physical Activity (PA) Levels in Children, Adolescent and Young Adults (AYA) survivors of childhood cancer
- Trial name
- NCT05792566
- Testing
- Atomic app
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Connecticut Children's Medical Center
Childhood Cancer, Survivorship
Aftercare of Childhood Cancer Survivors in Switzerland
The Aftercare of Childhood Cancer Survivors in Switzerland (ACCS) study is a multicenter cohort study designed to investigate transition of follow-up care from pediatric oncology to adult care in a prospective and longitudinal…
- Conditions
- Childhood Cancer, Survivorship, Transition
- Trial name
- ACCS (NCT04284189)
- Testing
- Transition model
- Where
- 3 sites in Switzerland
- Volunteers
- 140 people
- Sponsor
- Kantonsspital Aarau
Smoking, Cancer
Parent Willingness to Participate in Tobacco Trials in the Pediatric Clinical Setting
Little is known about what factors influence parental decisions to participate or to decline participation in tobacco trials offered in the pediatric clinical setting.
- Conditions
- Smoking, Cancer, Sickle Cell Disease
- Trial name
- NCT01673243
- Testing
- Questionnaire
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- St. Jude Children's Research Hospital
Acute Lymphoblastic Leukemia
Cognitive Intervention at the End of Therapy for Survivors of Childhood ALL Treated on TOTXVI
Computer-based cognitive training has been found to be helpful for improving attention and working memory in pediatric and adult patients with existing cognitive difficulties. A previous study was conducted at St.
- Trial name
- NCT03187977
- Testing
- Cognitive training
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- St. Jude Children's Research Hospital
PreDiabetes, Adult Children
An Open-Label Pilot Intervention Trial to Prevent Diabetes in Prediabetic Adult Survivors of Childhood Cancer
This is a first-in survivor, single-arm pilot study with the goal of establishing evidence of feasibility and safety of a combined pharmacologic (metformin) and lifestyle intervention (using an existing digital platform) to…
- Trial name
- NCT04742751
- Testing
- Metformin, Digital Intervention
- Where
- United States
- Volunteers
- 96 people
- Sponsor
- St. Jude Children's Research Hospital
Cancer Survivors
Virtual Exercise Training and Its Impact on Bone Compartments in Adult Survivors of Childhood Cancer
Childhood cancer is a rare disease but a significant cause of death in children and adolescents. The incidence of childhood cancer is 1case per 300 cases of adult cancer, but surviving to it has important sequels.
- Trial name
- 3D-BONE (NCT07022262)
- Testing
- Progressive resistance training plus impact loading
- Where
- Spain
- Volunteers
- 116 people
- Sponsor
- Universidad de Granada
Cancer, Glioma
Symptom Cluster Heterogeneity and Gut Microbiota Mechanisms in Childhood Cancer Survivors
Advances in medical care have significantly improved survival among children with cancer. In China, the 5-year survival rate has reached 71.9%.
- Conditions
- Cancer, Glioma, Leukemia (Both ALL and AML)
- Trial name
- SC-Het-GM-CCS (NCT07450872)
- Where
- China
- Volunteers
- 600 people
- Sponsor
- The Children's Hospital of Zhejiang University School of Medicine
Childhood Cancer Survivors, Fertility
Fertility and Ovarian Reserve in Female Childhood Cancer Survivors
Ovarian function impairment affects the quality of life of the survivors of paediatric cancer by impacting fertility, bone quality and mental and cognitive health.
- Conditions
- Childhood Cancer Survivors, Fertility, Ovarian Reserve, CED
- Trial name
- PRINCESS (NCT06626282)
- Where
- 3 sites in Belgium
- Volunteers
- 340 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Liege
Cardiovascular Risk, Pediatric Cancer
Vascular Assessment in Adult Survivors of Childhood Cancer
This is an observational study that will collect data from adult survivors of childhood cancer and compare it to data collected from age- and gender-matched controls for the purpose of assessing vascular risk among cancer…
- Trial name
- NCT02010190
- Where
- United States
- Volunteers
- 394 people, healthy volunteers welcome
- Sponsor
- St. Jude Children's Research Hospital
Acute Lymphoblastic Leukemia
Motor Proficiency And Physical Activity in Adult Survivors of Childhood Acute Lymphoblastic Leukemia (ALL)
The primary goal of this study is to provide comprehensive and objective information on impairments of musculoskeletal health, sensory function, and fitness among a large group of childhood ALL survivors, and to define high risk…
- Trial name
- NCT01047020
- Where
- United States
- Volunteers
- 807 people, healthy volunteers welcome
- Sponsor
- St. Jude Children's Research Hospital