Clinical trials: Survivor of Childhood Cancer
Smoking, Cancer
Parent Willingness to Participate in Tobacco Trials in the Pediatric Clinical Setting
Little is known about what factors influence parental decisions to participate or to decline participation in tobacco trials offered in the pediatric clinical setting.
- Conditions
- Smoking, Cancer, Sickle Cell Disease
- Trial name
- NCT01673243
- Testing
- Questionnaire
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- St. Jude Children's Research Hospital
Childhood Cancer Survivors
Virtual Health Insurance Navigation Pilot Program for Childhood Survivors (HINTII)
The investigators are conducting a Type I hybrid effectiveness-implementation trial to assess the effectiveness of HINT-S (synchronous) compared to enhanced usual care (EUC) in promoting health insurance literacy, thus reducing…
- Trial name
- HINTII (NCT05527392)
- Testing
- Health Insurance Navigation Tools Program
- Where
- United States
- Volunteers
- 529 people
- Sponsor
- Massachusetts General Hospital
Acute Lymphoblastic Leukemia, Pediatric, Pediatric ALL
Healthy Bones, Healthy Life: Habitual Physical Activity on Bone & Metabolic Health in Pediatric Cancer Survivors
This project will examine habitual physical activity, bone health, and insulin resistance in pediatric acute lymphocytic leukemia (ALL) and lymphoma cancer survivors at two time points: baseline and 6 months.
- Conditions
- Acute Lymphoblastic Leukemia, Pediatric, Pediatric ALL, Pediatric Lymphoma, Bone Loss
- Trial name
- HBHL (NCT04472286)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Nebraska
Muscle Weakness, Low Muscle Mass
Muscle Aging Phenotypes in Childhood Cancer Survivors
Childhood cancer survivors experience premature declines in muscle mass, strength, and physical function that contribute to morbidity and early mortality.
- Conditions
- Muscle Weakness, Low Muscle Mass, Sarcopenia
- Trial name
- NCT07531498
- Testing
- Multimodal Muscle Imaging and Functional Assessment, Multimodal Muscle Imaging and Neuromuscular Assessment, Comprehensive Muscle Phenotyping
- Where
- United States
- Volunteers
- 533 people, healthy volunteers welcome
- Sponsor
- St. Jude Children's Research Hospital
Pediatric Cancer
LIFE Cancer Survivorship Database for Pediatric Cancer
The purpose of this study is to develop a mechanism for utilizing the comprehensive clinical database of childhood cancer survivors at Childrens Hospital Los Angeles (CHLA) for research purposes.
- Trial name
- NCT01518400
- Where
- United States
- Volunteers
- 5,000 people
- Sponsor
- Children's Hospital Los Angeles
Childhood Cancer, Survivorship
A Multilevel Intervention to Improve Adherence to Childhood Cancer Survivorship
More than 80% of childhood cancer survivors develop serious or life-threatening late effects after cancer therapy, but <20% receive recommended survivorship care offered at cancer center survivorship clinics.
- Conditions
- Childhood Cancer, Survivorship, Health Care Utilization, Health Knowledge, Attitudes, Practice
- Trial name
- BRIDGES (NCT05448560)
- Testing
- Multi-level Intervention of shared model of survivorship care, Comparison Group
- Where
- 4 sites in United States
- Volunteers
- 240 people
- Sponsor
- Georgetown University
Pediatric Cancer
Improving Cognition and Behavior in Pediatric Cancer Survivors Using a Novel Mindful Attention Training
This pilot study will evaluate the cognitive and behavioral outcomes of using a novel, adaptive attention training in pediatric cancer survivors.
- Trial name
- NCT05000905
- Testing
- Adaptive Attention Training, Questionnaires
- Sponsor
- University of California, San Francisco
Hematopoietic and Lymphoid Cell Neoplasm, Malignant Solid Neoplasm
Reproducibility and Accuracy of a Portable System for Early Detection of Cardiac Dysfunction in Childhood Cancer Survivors
The clinical trial compares the reproducibility and accuracy of cardiac tonometry-based portable systems that may detect early cardiac dysfunction (SphygmoCor® Xcel and Oscar 2™ ambulatory blood pressure monitor) at home and in…
- Trial name
- NCT05138991
- Testing
- Echocardiogram Recording, Questionnaire Administration, Stress Cardiac Magnetic Resonance Imaging
- Where
- United States
- Volunteers
- 149 people, healthy volunteers welcome
- Sponsor
- City of Hope Medical Center
Childhood Cancer, Mobility Limitation
Telehealth Based Intervention to Improve Functional Capacity in Survivors of Childhood Cancer With Significantly Limited Exercise Tolerance
The participants are asked to take part in this clinical trial, a type of research study. The participants are SJLIFE study participants and may have a hard time exercising (exercise intolerance) due to side effects of cancer…
- Trial name
- NCT04714840
- Testing
- Exercise testing results, Individually tailored exercise program (INT), Generalized exercise recommendations (AC)
- Where
- United States
- Volunteers
- 181 people
- Sponsor
- St. Jude Children's Research Hospital
Cancer Survivor, Leukemia
Study of Long-Term Outcomes of Patients With Acute Lymphoblastic Leukemia Who Were Enrolled as Children on Clinical Trials EORTC-58741, EORTC-58831, EORTC-58832, or EORTC-58881 Between 1971 and 1998
RATIONALE: Studying medical records and collecting questionnaires from patients who were enrolled as children in clinical trials for acute lymphoblastic leukemia may help doctors learn about long-term effects of treatment and…
- Conditions
- Cancer Survivor, Leukemia, Long-term Effects Secondary to Cancer Therapy in Children
- Trial name
- NCT01298388
- Testing
- medical chart review, questionnaire administration, study of socioeconomic and demographic variables
- Volunteers
- 3,138 people
- Sponsor
- European Organisation for Research and Treatment of Cancer - EORTC
Pediatric Cancers
Carotid Artery Disease in Childhood Cancer Survivors
The goal of this clinical research study is to find out if long-term survivors of childhood head or neck cancer, who received radiation therapy as part of the overall treatment plan, are at increased risk of thickening or…
- Trial name
- NCT00591539
- Testing
- Carotid Ultrasound
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- M.D. Anderson Cancer Center
Leukemia, Lymphoma
Quality of Life of Adult Cancer Survivors Who Have Undergone a Previous Bone Marrow or Peripheral Stem Cell Transplant for a Childhood Hematologic Cancer
RATIONALE: Studying quality of life in cancer survivors may help determine the long-term effects of hematologic cancer and may help improve the quality of life for future cancer survivors.
- Conditions
- Leukemia, Lymphoma, Myelodysplastic Syndromes, Quality of Life
- Trial name
- NCT00126477
- Testing
- cognitive assessment, management of therapy complications, psychosocial assessment and care
- Where
- United States
- Volunteers
- 750 people
- Sponsor
- Fred Hutchinson Cancer Center
Cancer
Establishment of a Lifetime of Cohort of Adults Surviving Childhood Cancer
Childhood cancer predisposes to health risks that may not become apparent until many years after completion of therapy. The SJLIFE protocol is designed to establish a lifetime cohort of childhood cancer survivors treated at St.
- Trial name
- SJLIFE (NCT00760656)
- Where
- United States
- Volunteers
- 10,000 people
- Sponsor
- St. Jude Children's Research Hospital
Congenital Heart Disease (CHD), Hematologic Malignancy
Impact of Congenital Heart Disease on the Prognosis of Childhood Hematological Neoplasms: A Multicenter Cohort Study
This study aims to determine whether congenital heart disease increases chronic health risks and mortality in childhood hematological tumor survivors, explore potential shared genetic factors between these conditions, identify…
- Trial name
- NCT07249138
- Where
- 18 sites in China
- Volunteers
- 800 people
- Sponsor
- Children's Hospital of Fudan University
Early Detection of Cancer
National Breast and Thyroid Screening After a Treatment Received Against a Cancer During Childhood
The DENACAPST programme represents an important initiative to provide near nation-wide roll-out of an important cancer surveillance program for childhood cancer survivors.
- Trial name
- DENACAPST (NCT03183401)
- Where
- France
- Volunteers
- 2,000 people
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Pediatric Cancer
Pilot Evaluation of a Healthy Lifestyle Intervention for Adolescent and Young Adult Survivors of Pediatric Cancer
This is a feasibility and acceptability trial to test a newly developed healthy lifestyle intervention for adolescent and young adult survivors of pediatric cancer.
- Trial name
- NCT04839952
- Testing
- Healthy Lifestyles, Education-Only Control
- Where
- United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins All Children's Hospital
Anthracycline-induced Cardiotoxicity
Preventing Cardiac Sequelae in Pediatric Cancer Survivors
Cancer therapy can place childhood cancer survivors at increased risk for heart disease which can lead to significant illness or early death.
- Trial name
- PCS2 (NCT01805778)
- Where
- 6 sites in United States, Canada
- Volunteers
- 1,128 people
- Sponsor
- The Hospital for Sick Children
Bone Mineral Density, Childhood Cancer Survivors
Bone Mineral Density Status in Pediatric and Adolescent Survivors of Childhood Cancer With History of Bone Fracture
This research study is evaluating bone mineral density in childhood cancer survivors who have a history of bone fracture.
- Trial name
- NCT02355340
- Testing
- Dual energy x-ray absorptiometry (DXA), Peripheral quantitative computed tomography (pQCT)
- Where
- 2 sites in United States
- Volunteers
- 22 people
- Sponsor
- Dana-Farber Cancer Institute
Childhood Cancer, Hematopoietic and Lymphoid Cell Neoplasm
Mobile App to Help Survivors of Childhood Cancer Navigate Long-Term Follow-Up Care
This clinical trial studies the effectiveness of a newly developed survivorship mobile application (app) designed for survivors, or their caregivers, of childhood cancer to help them better navigate long-term follow-up care.
- Conditions
- Childhood Cancer, Hematopoietic and Lymphoid Cell Neoplasm, Malignant Solid Neoplasm
- Trial name
- NCT05641961
- Testing
- Survivorship mobile application, Questionnaires
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Cancer
A Web-Based Physical Activity Intervention in Adolescent Survivors of Childhood Cancer
Five year survival following a diagnosis of childhood cancer has reached 83%, making long term health outcomes among survivors an important concern.
- Trial name
- NCT01778127
- Testing
- Activity Monitor, Interactive Website, Educational Materials
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- St. Jude Children's Research Hospital