Clinical trials: Survivor of Childhood Cancer
Cancer, Treatment-Related, Late Effect
Testicular Function and Semen Quality in Male Childhood and Adolescent Cancer Survivors
Cancer treatment can affect the testicular function, including sperm and hormonal functions. The aim of this study is to assess the testicular function and semen quality in young men who recover from childhood and adolescent…
- Conditions
- Cancer, Treatment-Related, Late Effect, Semen Analysis
- Trial name
- NCT06587477
- Testing
- Hormonal profile, Semen analysis, Questionnaire
- Where
- China
- Volunteers
- 200 people
- Sponsor
- The University of Hong Kong
Cancer, Childhood Cancer
Bladder and Bone Effects of Pelvic Radiation Therapy in Childhood Cancer Survivors
The aim of this study is to measure and evaluate the effects of pelvic external beam radiation therapy (EBRT) on lower urinary tract (LUT) function and bone mineralization.
- Trial name
- NCT05818462
- Testing
- Uroflow testing, Bladder Scan, Dysfunctional Voiding Scoring System Survey
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- University of Colorado, Denver
Hypertension
Assessing Blood Pressure Remotely in Childhood Cancer Survivors
Second malignant neoplasms and cardiac late effects are primary drivers of serious non-recurrence morbidity and mortality in long term childhood cancer survivors.
- Trial name
- NCT02476162
- Testing
- iHealth Wireless Blood Pressure Monitor
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- St. Jude Children's Research Hospital
Tumors of the Central Nervous System, Childhood Cancer Survivors
Cardiovascular Disorders and Risk Factors in Childhood Cranial and Craniospinal Tumors Survivors
The purpose of research is to study to adverse cardiovascular disorder and risks factors in childhood cranial and craniospinal tumors survivors.
- Trial name
- NCT05641636
- Testing
- 12-lead ECG, hormone and lipid blood tests, echocardiography (Echo-CG), cardiopulmonary exercise testing (CPET) and pulse wave analysis
- Where
- Russia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Leukemia, Acute, Brain Neoplasms
Physical Activity and Quality of Life in Childhood Cancersurvivors- a Long-term Follow-up
The project intends to study physical functional capacity and degree of physical activity health related quality of life and fatigue.
- Conditions
- Leukemia, Acute, Brain Neoplasms, Physical Fitness, Quality of Life
- Trial name
- NCT07046481
- Testing
- Physical activity
- Sponsor
- Region Skane
Cancer
Wilderness Program for Adolescent and Young Adult Cancer Survivors
Young cancer survivors are at higher risk of cancer reoccurrence, frailty, suicidal ideation, sedentary behaviour, reduced quality of life, and reduced overall life expectancy, compared to their siblings or healthy young persons.
- Trial name
- WAYA (NCT04761042)
- Testing
- WAYA-Wilderness, WAYA-Holiday
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Mid Sweden University
Hypertension, Dyslipidemias
Communicating Health Information and Improving Coordination With Primary Care
Survivors of childhood cancer are known to be at higher risk of developing premature, serious cardiovascular disease compared with the general population.
- Conditions
- Hypertension, Dyslipidemias, Diabetes, Childhood Cancer
- Trial name
- CHIIP (NCT03104543)
- Testing
- Education, Test results only
- Where
- United States
- Volunteers
- 347 people
- Sponsor
- Fred Hutchinson Cancer Center
Ototoxicity, Drug-Induced, Ototoxicity, Radiation-Induced
Analysis of Risk Factors for Hearing Loss in Survivors of Cancer Occurred During Childhood, Adolescence or Young Adulthood
This study is aimed at people treated for cancer before the age of 25, who have been followed for at least 5 years, and who are now aged between 18 and 50. It is a prospective, multicenter, non-randomized study.
- Conditions
- Ototoxicity, Drug-Induced, Ototoxicity, Radiation-Induced, Pediatric Cancer
- Trial name
- RISP-OTOTOX (NCT06957132)
- Testing
- Audiogram
- Where
- 3 sites in France
- Volunteers
- 500 people
- Sponsor
- Gustave Roussy, Cancer Campus, Grand Paris
Cancer, Parent
Adapting The Fear Of Recurrence Therapy (FORT) for Parents and Establishing Acceptability and Feasibility
Clinical levels of fear of cancer recurrence (FCR) affect up to 59% of adult cancer survivors. Family caregivers experience equal or greater levels of FCR, which has been linked to lower quality of life and increased distress.
- Conditions
- Cancer, Parent, Fear of Cancer Recurrence, CBT
- Trial name
- Parent-FORT (NCT06872840)
- Testing
- Parent Fear of Recurrence Therapy (Parent-FORT)
- Where
- Canada
- Volunteers
- 36 people
- Sponsor
- University of Ottawa
Breast Neoplasms, Early Detection of Cancer
Promoting Breast Cancer Screening in Women Who Survived Childhood Cancer
The primary purpose of this study is to determine the impact of maximizing patient and primary care provider (PCP) activation on breast cancer surveillance rates among women previously treated with chest radiotherapy (RT) for a…
- Trial name
- NCT03435380
- Testing
- Patient activation, Primary care physician activation, Control
- Where
- 5 sites in United States
- Volunteers
- 314 people
- Sponsor
- Duke University
Brain and Central Nervous System Tumors, Cognitive/Functional Effects
Donepezil in Treating Young Patients With Primary Brain Tumors Previously Treated With Radiation Therapy to the Brain
RATIONALE: Donepezil may decrease the side effects caused by radiation therapy to the brain. PURPOSE: This clinical trial is studying how well donepezil works in treating young patients with primary brain tumors previously…
- Conditions
- Brain and Central Nervous System Tumors, Cognitive/Functional Effects, Long-term Effects Secondary to Cancer Therapy in Children, Neurotoxicity
- Trial name
- NCT00452868
- Testing
- Donepezil
- Where
- 2 sites in United States
- Volunteers
- 14 people
- Sponsor
- Wake Forest University Health Sciences
Childhood Osteosarcoma
The Impact of Cancer on the Physical and Psychosocial Well-being Among Childhood Osteosarcoma Survivors
The aim of the study is to examine the impact of cancer and treatment-related effects on the physical and psychosocial well-being and quality of life among Hong Kong Chinese survivors of childhood osteosarcoma.
- Trial name
- NCT03298971
- Testing
- Questionnaires
- Where
- Hong Kong
- Volunteers
- 240 people
- Sponsor
- The University of Hong Kong
ALL, Childhood, Leukemia, Lymphoblastic
Effects of Methylphenidate on Attention Deficits in Childhood Cancer Survivors
While neurocognitive impairments in attention, memory and executive functioning are commonly reported sequelae of childhood leukemia and brain tumors, studies have only recently begun to examine the treatment of attention…
- Conditions
- ALL, Childhood, Leukemia, Lymphoblastic, Leukemia, Lymphoblastic, Acute, Leukemia, Lymphoblastic, Acute, L1
- Trial name
- NCT01100658
- Testing
- Methylphenidate
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- University of Minnesota
Childhood Cancer Survivors, Fertility
Fertility and Ovarian Reserve in Female Childhood Cancer Survivors
Ovarian function impairment affects the quality of life of the survivors of paediatric cancer by impacting fertility, bone quality and mental and cognitive health.
- Conditions
- Childhood Cancer Survivors, Fertility, Ovarian Reserve, CED
- Trial name
- PRINCESS (NCT06626282)
- Where
- 3 sites in Belgium
- Volunteers
- 340 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Liege
Childhood Cancer, Survivorship
Sexual Function Screening in Childhood Cancer Survivors
This is a qualitative research study involving semistructured interviews and Think-Aloud methodology during completion of a clinical screening tool. All participants will undergo the same semistructured interviews.
- Conditions
- Childhood Cancer, Survivorship, Sexual Dysfunction
- Trial name
- NCT04066218
- Testing
- Interviews
- Where
- 2 sites in United States
- Volunteers
- 24 people
- Sponsor
- University of Colorado, Denver
Childhood Cancer, Cognitive Impairment
Cognitive and Motor Training in Pediatric Posterior Fossa Tumor Survivors
The purpose of this study is to create a rehabilitation program for children who survived posterior fossa tumors using the latest technology.
- Conditions
- Childhood Cancer, Cognitive Impairment, Motor Skills Disorders, Posterior Fossa Tumor
- Trial name
- NCT03951246
- Testing
- Cognitive and Motor Training
- Where
- Russia
- Volunteers
- 60 people
- Sponsor
- Federal Research Institute of Pediatric Hematology, Oncology and Immunology
Childhood Cancer, Childhood Cancer Survivors
Proof-of-Concept Testing of the Cardiovascular Health Equity Through Food (CHEF) Intervention in Childhood Cancer Survivors
The goal of the Cardiovascular Health Equity Through Food (CHEF) program is to make it easier for participants and families to cook and eat healthy foods during and following childhood cancer treatment with the long-term goal of…
- Trial name
- CHEF (NCT06609473)
- Testing
- CHEF Intervention Program
- Where
- 2 sites in United States
- Volunteers
- 17 people
- Sponsor
- Dana-Farber Cancer Institute
Childhood Cancer, Cardiac Toxicity
Translating ECHOS2 Into an mHealth Platform
Childhood cancer survivors are at an increased risk of cardiac toxicity due to prior anti-cancer therapy. However, adherence to cardiac screening in this population remains low.
- Conditions
- Childhood Cancer, Cardiac Toxicity, Pediatric Cancer
- Trial name
- ECHOS2 (NCT05923242)
- Testing
- Computerized Intervention Authoring Software (CIAS)
- Where
- United States
- Volunteers
- 73 people
- Sponsor
- Washington University School of Medicine
Childhood Cancer Survivors, Cardiotoxicity
Impact of Exercise Intensity on Cardiac Health in Young Adult Survivors of Childhood Cancer: The PULSE Trial
This trial aims to evaluate the impact of exercise intensity on cardiac health in young adult survivors of childhood cancer previously treated with anthracyclines.
- Conditions
- Childhood Cancer Survivors, Cardiotoxicity, Cardiovascular Diseases, Anthracycline-induced Cardiotoxicity
- Trial name
- PULSE (NCT07442578)
- Testing
- HIIT Exercise Program, MICT Exercise Program
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Dana-Farber Cancer Institute
Cancer, Pediatric Cancer
Shadows Edge Mobile Developing Resilience in Adolescent and Young Adult Cancer Survivors
This study evaluates the efficacy of an interactive mobile game, Shadow's Edge, on enhancing resilience, promoting identity development, and decreasing somatic symptoms among adolescent and young adult survivors of cancer.
- Trial name
- NCT04218682
- Testing
- Shadow's Edge Mobile Application Gameplay
- Where
- United States
- Volunteers
- 177 people
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago