Clinical trials: Survivors of Childhood Cancer
Cancer Survivor, Cognitive/Functional Effects
Educational and Skills Training Program for Parents of Childhood Cancer Survivors Who Have Neurobehavioral Dysfunction
RATIONALE: An educational and skills training program for the parent of a childhood cancer survivor with neurobehavioral dysfunction may help improve the child's school performance, thinking ability, and behavior.
- Conditions
- Cancer Survivor, Cognitive/Functional Effects, Leukemia, Long-term Effects Secondary to Cancer Therapy in Children
- Trial name
- NCT00713505
- Testing
- educational intervention, psychosocial assessment and care
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- City of Hope Medical Center
School Attendance, Academic Level
SchoolCare: A Social Intervention Introducing Telepresence Robots and School Navigation to Reduce School Fragmentation for Children Undergoing Cancer Treatment
Advances in pediatric cancer treatment have led to significant improvements in survival rates, where 5-year survival now exceeds 85%.
- Conditions
- School Attendance, Academic Level, Childhood Cancer Survivors, Social Well-being
- Trial name
- SchoolCare (NCT07398677)
- Testing
- Telepresence robot, School Navigator, Teleteaching and technical support
- Where
- 3 sites in Denmark
- Volunteers
- 128 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Childhood Solid Tumor
French Childhood Cancer Survivor Study
The FCCSS is a multicentric national large-scale collaborative population-based study of children treated for a solid tumor before 2000 in France and before the age of 19 years.
- Trial name
- FCCSS (NCT01620372)
- Where
- 36 sites in France
- Volunteers
- 18,000 people
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Childhood Cancer
FAMily Oriented Support (FAMOS): Psychosocial Intervention for Childhood Cancer Survivors and Their Families
To investigate whether a home-based psychosocial family intervention that takes place shortly after ending the primary medical treatment can help families adjust to their cancer-related psychological issues.
- Trial name
- NCT02200731
- Testing
- FAMOS: psychosocial family intervention
- Where
- Denmark
- Volunteers
- 185 people, healthy volunteers welcome
- Sponsor
- Pernille Bidstrup
Anthracycline Induced Cardiotoxicity
Late Anthracycline Induced Cardiotoxicity- Childhood Cancer Survivors
Anthracyclines treat up to 60% of childhood malignancies with remarkable improvements survival rates. Unfortunately anthracyclines are associated with an increased cardiomyopathy risk.
- Trial name
- NCT04852965
- Where
- United Kingdom
- Volunteers
- 103 people
- Sponsor
- Queen's University, Belfast
Survivors of Childhood Cancer
A Mobile Phone Intervention to Promote Adherence to Survivorship Care Among Adolescent and Young Adult Cancer Survivors
Adolescents and young adults (AYA) survivors of childhood cancer receive inadequate surveillance for treatment-related late effects.
- Trial name
- NCT05000359
- Testing
- text messaging intervention
- Where
- United States
- Sponsor
- Jonsson Comprehensive Cancer Center
Childhood Cancer, Childhood Cancer Survivors
Proof-of-Concept Testing of the Cardiovascular Health Equity Through Food (CHEF) Intervention in Childhood Cancer Survivors
The goal of the Cardiovascular Health Equity Through Food (CHEF) program is to make it easier for participants and families to cook and eat healthy foods during and following childhood cancer treatment with the long-term goal of…
- Trial name
- CHEF (NCT06609473)
- Testing
- CHEF Intervention Program
- Where
- 2 sites in United States
- Volunteers
- 17 people
- Sponsor
- Dana-Farber Cancer Institute
Pediatric Cancers
Carotid Artery Disease in Childhood Cancer Survivors
The goal of this clinical research study is to find out if long-term survivors of childhood head or neck cancer, who received radiation therapy as part of the overall treatment plan, are at increased risk of thickening or…
- Trial name
- NCT00591539
- Testing
- Carotid Ultrasound
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- M.D. Anderson Cancer Center
Childhood Osteosarcoma
The Impact of Cancer on the Physical and Psychosocial Well-being Among Childhood Osteosarcoma Survivors
The aim of the study is to examine the impact of cancer and treatment-related effects on the physical and psychosocial well-being and quality of life among Hong Kong Chinese survivors of childhood osteosarcoma.
- Trial name
- NCT03298971
- Testing
- Questionnaires
- Where
- Hong Kong
- Volunteers
- 240 people
- Sponsor
- The University of Hong Kong
Medulloblastoma, Childhood, Survivorship
Cognitive Rehabilitation for Survivors of Childhood Medulloblastoma Using Real Time Hemodynamic Neurofeedback
This study will evaluate a new way to help childhood medulloblastoma survivors improve their thinking and memory skills. Many survivors experience long term challenges with attention and working memory because of the tumor and…
- Trial name
- NCT07830134
- Testing
- rt fMRI Neurofeedback (DLPFC), rt fMRI Neurofeedback (PAC)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- St. Jude Children's Research Hospital
Acute Lymphoblastic Leukemia
Motor Proficiency And Physical Activity in Adult Survivors of Childhood Acute Lymphoblastic Leukemia (ALL)
The primary goal of this study is to provide comprehensive and objective information on impairments of musculoskeletal health, sensory function, and fitness among a large group of childhood ALL survivors, and to define high risk…
- Trial name
- NCT01047020
- Where
- United States
- Volunteers
- 807 people, healthy volunteers welcome
- Sponsor
- St. Jude Children's Research Hospital
Osteopenia
Study of Adults With Low Growth Hormone Who Survived Childhood Cancer Where Treatment Caused Low Bone Density
The purpose of this project is to evaluate the hypothesis that bisphosphonate treatment given to growth hormone deficient patients (regardless of current growth hormone replacement therapy status and without changing that status)…
- Trial name
- NCT00145704
- Testing
- bisphosphonate therapy (risedronate), Vitamin D supplement, Calcium
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- State University of New York - Upstate Medical University
Osteoporosis
Fosamax for Childhood Cancer Survivors
Survivors of childhood cancers face a variety of long-term problems. The investigators' recent study found that osteoporosis and osteopenia were common among these patients.
- Trial name
- NCT00391404
- Testing
- Alendronate
- Where
- Hong Kong
- Volunteers
- 100 people
- Sponsor
- Chinese University of Hong Kong
ALL, Childhood, Leukemia, Lymphoblastic
Effects of Methylphenidate on Attention Deficits in Childhood Cancer Survivors
While neurocognitive impairments in attention, memory and executive functioning are commonly reported sequelae of childhood leukemia and brain tumors, studies have only recently begun to examine the treatment of attention…
- Conditions
- ALL, Childhood, Leukemia, Lymphoblastic, Leukemia, Lymphoblastic, Acute, Leukemia, Lymphoblastic, Acute, L1
- Trial name
- NCT01100658
- Testing
- Methylphenidate
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- University of Minnesota
Childhood Cancer
Childhood Cancer Survivors' Knowledge of Diagnosis,Treatment and Risk of Late Effects: Specialized Survivorship Clinic
This two-part research study will compare childhood cancer survivors receiving specialized follow-up care in the REACH for Survivorship clinic to patients receiving routine follow-up care.
- Trial name
- NCT01223872
- Testing
- interview, clinic visit and interview, interviews and clinic visit
- Where
- United States
- Volunteers
- 188 people
- Sponsor
- Vanderbilt University Medical Center
Cardiovascular Disease
Defining Late Onset Occult Asymptomatic Cardiotoxicity in Childhood Cancer Survivors Exposed to Anthracycline Therapy
The main hypothesis being tested is that magnetic resonance imaging and serologic biomarkers of apoptosis and extracellular matrix remodeling will precede echocardiographic indices of systolic and diastolic function among…
- Trial name
- NCT01671696
- Testing
- Cardiac MRI
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Connecticut Children's Medical Center
Childhood Cancer Survivors, Fertility
Fertility and Ovarian Reserve in Female Childhood Cancer Survivors
Ovarian function impairment affects the quality of life of the survivors of paediatric cancer by impacting fertility, bone quality and mental and cognitive health.
- Conditions
- Childhood Cancer Survivors, Fertility, Ovarian Reserve, CED
- Trial name
- PRINCESS (NCT06626282)
- Where
- 3 sites in Belgium
- Volunteers
- 340 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Liege
Autonomic Dysfunction, Childhood Cancer
Cardiac Autonomic Dysfunction in Childhood Cancer Survivors
This study is being done to evaluate heart rate activity and sleep patterns, among participants in the Long-Term Follow-Up (LTFU) study.
- Trial name
- NCT05132673
- Sponsor
- St. Jude Children's Research Hospital
Survivors of Childhood Cancer, Bladder Dysfunction
Impact of Chemotherapy on Urinary Biomarkers and Non-Invasive Urodynamics in Children
The over-arching aim of this study is to evaluate the effects of two specific anti-cancer chemotherapies, vincristine and doxorubicin, on bladder function and urine composition.
- Trial name
- NCT04993859
- Testing
- Non-invasive Urodynamic Test (niUDS), Urinary proteomic screen, Dysfunctional Voiding Symptom Score Survey (DVSS)
- Where
- United States
- Volunteers
- 152 people
- Sponsor
- University of Colorado, Denver
Childhood Cancer
SurvivorLink: Scalability of an Electronic Personal Health Record
Previous research suggests that children and adolescents with cancer are at heightened risk of late effects that can occur months or years after cancer treatment, yet little is known about programs that increase their return for…
- Trial name
- NCT03543852
- Testing
- SurvivorLink
- Where
- 12 sites in United States
- Volunteers
- 542 people
- Sponsor
- Emory University