Clinical trials: Survivors of Childhood Cancer
Cancer Survivor, Childhood Acute Lymphoblastic Leukemia in Remission
Culturally Adapted Parenting Intervention for Spanish-Speaking Parents in Improving Outcomes of Younger Acute Lymphoblastic Leukemia or Acute Myeloid Leukemia Survivors at Risk for Late Neurocognitive Effects
This pilot clinical trial studies a culturally adapted skills training and educational intervention in guiding parents of younger acute lymphoblastic leukemia (ALL) or acute myeloid leukemia (AML) survivors at risk for long-term…
- Conditions
- Cancer Survivor, Childhood Acute Lymphoblastic Leukemia in Remission, Childhood Acute Myeloid Leukemia in Remission, Cognitive Side Effects of Cancer Therapy
- Trial name
- NCT02559557
- Testing
- Educational Intervention, Quality-of-Life Assessment, Questionnaire Administration
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- City of Hope Medical Center
Childhood Cancer
FAMily Oriented Support (FAMOS): Psychosocial Intervention for Childhood Cancer Survivors and Their Families
To investigate whether a home-based psychosocial family intervention that takes place shortly after ending the primary medical treatment can help families adjust to their cancer-related psychological issues.
- Trial name
- NCT02200731
- Testing
- FAMOS: psychosocial family intervention
- Where
- Denmark
- Volunteers
- 185 people, healthy volunteers welcome
- Sponsor
- Pernille Bidstrup
Pediatric Cancer
Improving Cognition and Behavior in Pediatric Cancer Survivors Using a Novel Mindful Attention Training
This pilot study will evaluate the cognitive and behavioral outcomes of using a novel, adaptive attention training in pediatric cancer survivors.
- Trial name
- NCT05000905
- Testing
- Adaptive Attention Training, Questionnaires
- Sponsor
- University of California, San Francisco
Childhood Cancer
Examining a Training Program for for Acute Lymphoblastic Leukemia Childhood Cancer Survivors
Acute lymphoblastic leukemia (ALL) is the most common pediatric malignancy, with the peak incidences occurring in children two to five years of age.
- Trial name
- JUMP (NCT05086354)
- Testing
- JUMP
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Maryland, Baltimore
Childhood Cancer Survivors, Fertility
Fertility and Ovarian Reserve in Female Childhood Cancer Survivors
Ovarian function impairment affects the quality of life of the survivors of paediatric cancer by impacting fertility, bone quality and mental and cognitive health.
- Conditions
- Childhood Cancer Survivors, Fertility, Ovarian Reserve, CED
- Trial name
- PRINCESS (NCT06626282)
- Where
- 3 sites in Belgium
- Volunteers
- 340 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Liege
Childhood Cancer
Using Information Communication Technology to Deliver Brief Motivational Interviewing
This study aims to examine the efficacy of using Information Communication Technology (ICT) to deliver brief Motivational Interviewing (BMI) to promote regular physical activity among Hong Kong Chinese childhood cancer survivors.
- Trial name
- NCT03859271
- Testing
- Brief motivational interviewing
- Where
- 2 sites in China, Hong Kong
- Volunteers
- 161 people
- Sponsor
- The University of Hong Kong
Chemotherapy Effect, Dental Caries
Prevalence of Long-term Dental Effects of Chemotherapy in Childhood Cancer Survivors Diagnosed With Cancer Before the Age of 10
To date, there are no methods for assessing the risk of oral developmental defects that could predict long-term adverse effects in childhood cancer survivors.
- Conditions
- Chemotherapy Effect, Dental Caries, Malocclusion, Childhood Cancer
- Trial name
- NCT06517927
- Testing
- Clinical and radiographic dental examination
- Where
- Belgium
- Volunteers
- 142 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Childhood Cancer, Survivorship
Sexual Function Screening in Childhood Cancer Survivors
This is a qualitative research study involving semistructured interviews and Think-Aloud methodology during completion of a clinical screening tool. All participants will undergo the same semistructured interviews.
- Conditions
- Childhood Cancer, Survivorship, Sexual Dysfunction
- Trial name
- NCT04066218
- Testing
- Interviews
- Where
- 2 sites in United States
- Volunteers
- 24 people
- Sponsor
- University of Colorado, Denver
Cancer
MAAT For Young Adult Cancer Survivors
The goal of this clinical trial is to pilot-test a modified version of telehealth-delivered Memory and Attention Adaption Training (MAAT) that is tailored to young adult childhood cancer survivors (ages 18-39; MAAT-YS) with…
- Trial name
- MAAT-YACCS (NCT06150976)
- Testing
- MAAT-YS
- Where
- 3 sites in United States
- Volunteers
- 7 people
- Sponsor
- University of Pittsburgh
Survivors of Childhood Cancer
A Mobile Phone Intervention to Promote Adherence to Survivorship Care Among Adolescent and Young Adult Cancer Survivors
Adolescents and young adults (AYA) survivors of childhood cancer receive inadequate surveillance for treatment-related late effects.
- Trial name
- NCT05000359
- Testing
- text messaging intervention
- Where
- United States
- Sponsor
- Jonsson Comprehensive Cancer Center
Brain Metastases, Adult, Primary Brain Tumor
Survivorship Study of Cancer Patients Who Received Cranial Radiation Therapy
This study represents a survivorship protocol that focuses on cognition and health-related quality of life (HRQoL) in cancer patients that have received prior brain irradiation.
- Conditions
- Brain Metastases, Adult, Primary Brain Tumor, Lung Cancer
- Trial name
- SPiRiT (NCT04567251)
- Testing
- Noona® application
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Duke University
Cancer, Glioma
Symptom Cluster Heterogeneity and Gut Microbiota Mechanisms in Childhood Cancer Survivors
Advances in medical care have significantly improved survival among children with cancer. In China, the 5-year survival rate has reached 71.9%.
- Conditions
- Cancer, Glioma, Leukemia (Both ALL and AML)
- Trial name
- SC-Het-GM-CCS (NCT07450872)
- Where
- China
- Volunteers
- 600 people
- Sponsor
- The Children's Hospital of Zhejiang University School of Medicine
Pediatric Cancer Survivor, Survivorship
Digital Self-Management and Peer Mentoring Intervention
This study tests how helpful a digital self-management and peer mentoring program is to young adult survivors of childhood cancer to improve their ability to manage their survivorship care as they transition from pediatric to…
- Conditions
- Pediatric Cancer Survivor, Survivorship, Cancer
- Trial name
- NCT06763770
- Testing
- Managing Your Health (MYH), The Usual Care + Educational Control
- Where
- 2 sites in United States
- Volunteers
- 300 people
- Sponsor
- Rutgers, The State University of New Jersey
Childhood Cancer, Hematopoietic and Lymphoid Cell Neoplasm
Mobile App to Help Survivors of Childhood Cancer Navigate Long-Term Follow-Up Care
This clinical trial studies the effectiveness of a newly developed survivorship mobile application (app) designed for survivors, or their caregivers, of childhood cancer to help them better navigate long-term follow-up care.
- Conditions
- Childhood Cancer, Hematopoietic and Lymphoid Cell Neoplasm, Malignant Solid Neoplasm
- Trial name
- NCT05641961
- Testing
- Survivorship mobile application, Questionnaires
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Cancer, Pediatric Cancer
Shadows Edge Mobile Developing Resilience in Adolescent and Young Adult Cancer Survivors
This study evaluates the efficacy of an interactive mobile game, Shadow's Edge, on enhancing resilience, promoting identity development, and decreasing somatic symptoms among adolescent and young adult survivors of cancer.
- Trial name
- NCT04218682
- Testing
- Shadow's Edge Mobile Application Gameplay
- Where
- United States
- Volunteers
- 177 people
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Survivors of Childhood Cancer, Bladder Dysfunction
Impact of Chemotherapy on Urinary Biomarkers and Non-Invasive Urodynamics in Children
The over-arching aim of this study is to evaluate the effects of two specific anti-cancer chemotherapies, vincristine and doxorubicin, on bladder function and urine composition.
- Trial name
- NCT04993859
- Testing
- Non-invasive Urodynamic Test (niUDS), Urinary proteomic screen, Dysfunctional Voiding Symptom Score Survey (DVSS)
- Where
- United States
- Volunteers
- 152 people
- Sponsor
- University of Colorado, Denver
Childhood Cancer
Preparing for Life and Academics for Young Childhood Cancer Survivors
The goal of this clinical trial is to test and improve an online program for caregivers of young childhood cancer survivors called the Preparing for Life and Academics for Young Survivors program (PLAY).
- Trial name
- PLAY (NCT06769334)
- Testing
- PLAY Program
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- Nationwide Children's Hospital
Childhood Cancers
Cardiovascular Function in Adult Survivors of Childhood Malignancies
Anthracyclines have been used commonly to treat children with solid tumours and haematological malignancies and have led to their increased survival. Nonetheless, anthracycline has the side effect of cardiotoxicity.
- Trial name
- NCT01415999
- Where
- China
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Survivorship, Cancer
ONLOOP Trial: Evaluating a New Surveillance and Support System for Survivors of Childhood Cancer in Ontario
The treatments that aim to cure cancer in children can lead to "late effects" such as second cancers and heart disease. Screening tests can help find late effects, but most adult survivors of childhood cancer do not complete…
- Conditions
- Survivorship, Cancer, Heart Diseases, Secondary Cancer
- Trial name
- NCT05832138
- Testing
- ONLOOP program
- Volunteers
- 900 people
- Sponsor
- The Hospital for Sick Children
Childhood Cancer
Assessment of Remote Approaches for Identification of Autonomic Dysfunction Among Survivors of Leukemia and Lymphoma
This study seeks to determine if diagnosing cardiac autonomic dysfunction (AD) can be done remotely with the same accuracy as in-person testing.
- Trial name
- NCT06747910
- Testing
- Exercise Intervention - Ewing Battery Assessment, Questionnaire Administration, Medical Device Usage and Evaluation
- Where
- United States
- Volunteers
- 188 people
- Sponsor
- St. Jude Children's Research Hospital