Clinical trials: Sutures
Cardiovascular Disease
Comparison of Cyanoacrylate Tissue Adhesive and Suture for Closure of Cardiac Device Pockets
The purpose of this study is to determine whether cyanoacrylate tissue adhesive is as effective as polyglactin 910 suture for surgical closure of cardiac device pockets.
- Trial name
- NCT00674128
- Testing
- Cyanoacrylate tissue adhesive (Dermabond), Polyglactin 910 suture (Vicryl)
- Where
- United States
- Volunteers
- 103 people
- Sponsor
- Mayo Clinic
Labral Tear, Glenoid, Acetabular Labrum Tear
Safety and Performance of MICRORAPTOR™ Suture Anchors in Shoulder and Hip
This is a prospective, multi-center, PMCF study to evaluate the safety and performance of the MICRORAPTOR REGENESORB suture anchors, MICRORAPTOR Knotless REGENESORB suture anchors, and MICRORAPTOR Knotless PEEK suture anchors…
- Conditions
- Labral Tear, Glenoid, Acetabular Labrum Tear, Bankart Lesions, Anterior Shoulder Instability
- Trial name
- NCT03985839
- Testing
- MICRORAPTOR™ REGENESORB™ Suture Anchor, MICRORAPTOR™ Knotless REGENESORB™ Suture Anchor, MICRORAPTOR™ Knotless PEEK Suture Anchor
- Where
- 12 sites in United States
- Volunteers
- 298 people
- Sponsor
- Smith & Nephew, Inc.
Soft Tissue to Bone Fixation
PMCF Study on PEEK Suture Anchors for Hip Indications
Post-market clinical follow-up (PMCF) on the PEEK Suture Anchors in the hip.
- Trial name
- NCT03814044
- Testing
- PEEK Suture Anchors
- Where
- 4 sites in United States
- Volunteers
- 149 people
- Sponsor
- Smith & Nephew, Inc.
Wound; Hip
Prospective Randomized Trial of Stratafix vs. Vicryl in Total Hip Arthroplasty.
The STRATAFIX (Ethicon, Johnson and Johnson, Somerville, New Jersey) Knotless Tissue Control suture device is a barbed suture that uses anchor technology to securely engage with the soft tissues while also eliminating the need…
- Trial name
- NCT03285555
- Testing
- STRATIFIX, VICRYL
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- The Cleveland Clinic
Polyp of Colon, Fistula
Closure of Mucosal and Submucosal Defects in the Gastrointestinal Tract Using the Novel X-Tack Endoscopic Suturing Device
After removing large polyps from the gastrointestinal tract, gastroenterologists close the new defect with devices to prevent complications like bleeding or the development of a leak.
- Trial name
- NCT04925271
- Testing
- X-Tack, Overstitch
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Thomas Jefferson University
Laceration
Trial Comparing Cosmetic Outcomes of Pediatric Laceration Closure Using Skin Glue, Medical Tape Versus Stitches
There are several methods of closing a skin cut: stitches, skin glue, and medical tape. Stitches have been used for a long time to close skin cuts.
- Trial name
- NCT03280628
- Testing
- Absorbable Sutures, Steri-Strips, Dermabond
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Vanderbilt University Medical Center
Obesity
ESSENTIAL Trial™ Sham Cross-over
This is a multicenter, un-blinded, open label, pivotal supplemental study to G130163 intended to evaluate the safety and efficacy of treating previous sham subjects in the Essential pivotal trial (IDE#G130163) with the active…
- Trial name
- NCT02279420
- Testing
- g-Cath EZ™ Suture Anchor Delivery Catheter
- Where
- 11 sites in United States
- Volunteers
- 73 people
- Sponsor
- USGI Medical
Intraocular Lens Dislocation
Late Dislocation of Intraocular Lens (IOL) Following Cataract Surgery: an Evaluation of Two Different Surgical Methods
A prospective randomized study on patients with late in the bag intraocular lens (IOL) dislocation, after cataract surgery. To obtain normal visual function, these patients needs surgery.
- Trial name
- NCT01784926
- Testing
- Intraocular lens repositioning by scleral suturing, Intraocular lens exchange with retropupillary iris-claw lens
- Where
- Norway
- Volunteers
- 104 people
- Sponsor
- Oslo University Hospital
Surgical Incisions
Prineo (Dermabond Protape) Versus Sutures for Full-thickness Surgical Incisions
This is a prospective, controlled, randomized, multi-center clinical study of up to 80 subjects with full thickness surgical incisions.
- Trial name
- NCT00557947
- Testing
- Suture, Dermabond Protape (Prineo)
- Where
- 5 sites in Belgium, Germany and 2 more
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Ethicon, Inc.
Instability, Joint
Safety and Performance of the SUTUREFIX ULTRA and SUTUREFIX CURVED Suture Anchors in Shoulder and Hip Arthroscopic Repair
The scientific justification is to fulfill post-market clinical requirements in order to support re-certification of the CE-Mark for this marketed product and to look into safety and efficacy.
- Trial name
- NCT03691298
- Testing
- SUTUREFIX ULTRA Suture Anchor and SUTUREFIX CURVED Suture Anchor
- Where
- 9 sites in United States, Denmark and 4 more
- Volunteers
- 83 people
- Sponsor
- Smith & Nephew Orthopaedics AG
Macromastia
Study of Prineo (Dermabond Protape) Versus Sutures in Breast Procedures
This is a prospective, controlled, randomized, multi-center clinical study of up to 80 patients with full thickness surgical incisions associated with bi-lateral breast procedures.
- Trial name
- NCT00558246
- Testing
- Dermabond Protape (Prineo), Suture
- Where
- 5 sites in Belgium, Germany and 2 more
- Volunteers
- 79 people
- Sponsor
- Ethicon, Inc.
Obesity
Incisionless Treatment for Patients With Inadequate Weight Loss Following Roux-en-Y Gastric Bypass
It is estimated that up to 20% of patients who have Roux-en-Y Gastric Bypass (RYGB) surgery will not meet their weight loss goal, or may even regain some of the weight they initially lost.
- Trial name
- NCT00394212
- Testing
- Transoral Suturing
- Where
- 10 sites in United States
- Volunteers
- 77 people
- Sponsor
- C. R. Bard
Cesarean Section; Complications, Placenta Previa
Long Term Comparison of Two Different Techniques of Uterine Cesarean Incision Closure
Cesarean section (C/S) is an operation most commonly performed in Obstetrics and Gynecology Clinics. Complications related with incomplete healing of Kerr uterine incision after C/S (adhesions, separation (dehiscence)…
- Conditions
- Cesarean Section; Complications, Placenta Previa, Placenta Accreta
- Trial name
- NCT01289262
- Testing
- Purse string closure technique, Continuously locked closure technique
- Where
- Turkey (Türkiye)
- Volunteers
- 168 people
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
Breast Ptosis, Obesity
Evaluation of Dermal Closure With an Absorbable Barbed Suture as Compared to a Conventional Absorbable Suture
The objective of this study is to evaluate the use of an absorbable barbed suture as compared to a conventional absorbable suture when used for dermal closure during certain body contouring procedures.
- Trial name
- NCT00959374
- Testing
- V-Loc 180/90 Wound Closure Device, 3-0 Monocryl Absorbable Sutures
- Where
- 8 sites in United States, Germany
- Volunteers
- 229 people, healthy volunteers welcome
- Sponsor
- Medtronic - MITG
Breast Cancer
Coated VICRYL* Plus Suture Compared to Chinese Silk in Scheduled Breast Cancer Surgery
This is a 90-day study to evaluate cosmetic outcome and Surgical Site Infection in approximately 100 patients from 6 centers in China undergoing scheduled modified radical mastectomy for breast cancer.
- Trial name
- NCT00768222
- Testing
- silk suture, VICRYL* Plus suture
- Where
- 6 sites in China
- Volunteers
- 101 people
- Sponsor
- Ethicon, Inc.
Obesity
Endoscopic Suturing System for Tissue Apposition
The objective of this feasibility trial is to evaluate the Ethicon Endo-Surgery Endoscopic Suturing System (ESS) for tissue apposition and reduction of the size of a dilated GJ anastomosis in subjects who are regaining weight…
- Trial name
- NCT00495222
- Testing
- Tissue plication, Endoscopic Suturing System
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Ethicon Endo-Surgery
Atrial Fibrillation
Femoral Vein Hemostasis After Ablation for Atrial Fibrillation With Manual Pressure Versus a Figure of 8 Suture
Patients who undergo ablation for AF typically have 2 sheaths placed in each groin, including a large sheath when the Cryo Balloon is used for pulmonary vein isolation.
- Trial name
- Figure 8 (NCT03040661)
- Testing
- Ablation for atrial fibrillation.
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Inova Health Care Services
Brow Ptosis, Surgical Wound
An Analysis of Dermabond vs. Non-Absorbable Sutures in Skin Closure for Brow Ptosis Procedures
The goal of this clinical trial is to compare Dermabond with non-absorbable sutures in skin closure after brow ptosis surgery. The main questions it aims to answer are: if Dermabond provides equivalent wound healing compared to…
- Trial name
- NCT05981443
- Testing
- Dermabond, Non-Absorbable Sutures
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Cody Blanchard
Pregnancy, Cesarean Section
Comparison of Staples Versus Prolene Suture for Skin Closure at Cesarean Delivery
Currently different materials are used to close the skin after a cesarean delivery, including absorbable suture, non-absorbable suture and staples.
- Trial name
- NCT01509950
- Testing
- Staples, Prolene non-absorbable sutures, Absorbable Sutures
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Stanford University
Wound Closure
Symmetric on Total Knee Arthroplasty (TKA)
A post-marketing prospective, multicenter, randomized controlled study to evaluate the wound closure efficiency of STRATAFIX™ Symmetric PDS™ Plus Knotless Tissue Control Device (STRATAFIX Symmetric PDS Plus) compared to…
- Trial name
- SFX (NCT03305887)
- Testing
- "STRATAFIX™ Symmetric" Knotless Tissue, VICRYL® PLUS, "STRATAFIX Spiral" sutures
- Where
- 7 sites in China
- Volunteers
- 184 people
- Sponsor
- Johnson & Johnson Medical, China