Clinical trials: Sweat
Hidradenitis Suppurativa
Study of Single Doses of SBT777101 in Subjects With Hidradenitis Suppurativa
This study will test the safety and effects of SBT777101 when given as a single dose to subjects with hidradenitis suppurativa. Increasing dose levels will be given after the safety at lower dose levels is shown.
- Trial name
- Regulate-HS (NCT06361836)
- Testing
- SBT777101
- Where
- 6 sites in United States
- Volunteers
- 24 people
- Sponsor
- Sonoma Biotherapeutics, Inc.
Hidradenitis Suppurativa (HS)
Study of Efficacy and Safety of Secukinumab in Chinese Adult Patients With Moderate to Severe Hidradenitis Suppurativa
This is a post-approval commitment study to evaluate efficacy, and safety of two dosing regimens of secukinumab (AIN457), 300 mg every four weeks (Q4W) and every two weeks (Q2W), in Chinese adult patients with moderate to severe…
- Trial name
- NCT07489573
- Testing
- Secukinumab
- Where
- 10 sites in China
- Volunteers
- 36 people
- Sponsor
- Novartis Pharmaceuticals
Cystic Fibrosis
Novel Point-of-care Sweat Chloride Testing Device for Monitoring CFTR Function
This study is being done to test a device called micro Sweat Test Patch (mSTP or µSTP). The study team will compare the standard of care (SOC) method of sweat testing with a novel sweat test technique using an integrated micro…
- Trial name
- SWEAT CF (NCT07414810)
- Testing
- micro Sweat Test Patch (mSTP), Sweat Testing using SOC
- Where
- 2 sites in United States
- Volunteers
- 300 people
- Sponsor
- Emory University
Hidradenitis Suppurativa (HS)
Safety and Efficacy of Soquelitinib in Adults With Hidradenitis Suppurativa
Safety and Efficacy of Soquelitinib in Adults with Hidradenitis Suppurativa
- Trial name
- NCT07828860
- Testing
- Soquelitinib
- Where
- 11 sites in United States
- Volunteers
- 25 people
- Sponsor
- Corvus Pharmaceuticals, Inc.
Hidradenitis Suppurativa
A Study of the Efficacy and Safety of Brensocatib in Adults With Moderate to Severe Hidradenitis Suppurativa (HS)
The primary purpose of the study is to evaluate the effect of brensocatib compared with placebo.
- Trial name
- CEDAR (NCT06685835)
- Testing
- Brensocatib
- Where
- 72 sites in United States, Australia and 8 more
- Volunteers
- 214 people
- Sponsor
- Insmed Incorporated
Hidradenitis Suppurativa
A Study of Bermekimab for the Treatment of Participants With Moderate to Severe Hidradenitis Suppurativa
The purpose of this study is to evaluate the clinical efficacy of bermekimab in participants with moderate to severe Hidradenitis Suppurativa (HS).
- Trial name
- LYRA (NCT04988308)
- Testing
- Bermekimab, Adalimumab
- Where
- 54 sites in United States, Australia and 6 more
- Volunteers
- 151 people
- Sponsor
- Janssen Research & Development, LLC
Hidradenitis Suppurativa (HS)
Efficacy and Safety Study of IFX-1 in Patients With Moderate to Severe Hidradenitis Suppurativa (HS)
The purpose of this study is to determine whether IFX-1 is safe and effective in the treatment of moderate to severe hidradenitis suppurativa.
- Trial name
- SHINE (NCT03487276)
- Testing
- IFX-1
- Where
- 41 sites in United States, Bulgaria and 7 more
- Volunteers
- 179 people
- Sponsor
- InflaRx GmbH
Hyperhydrosis, Depression
Excessive Sweating Caused by Antidepressants: Measurement and Treatment With Glycopyrrolate (AIDES-G)
The study consists of measurement of antidepressant-induced excessive sweating and its treatment with an experimental medication, glycopyrrolate (approved to treat ulcers), which will be added to the antidepressant.
- Trial name
- AIDES-G (NCT01588717)
- Testing
- Glycopyrrolate
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Thomas Jefferson University
Axillary Hyperhidrosis
Clinical Evaluation of the miraDry System in Subjects With Hyperhidrosis
The purpose of this study is to determine whether treatment by the miraDry System can safely reduce the severity of axillary hyperhidrosis (excessive underarm sweating).
- Trial name
- NCT01091129
- Testing
- miraDry System (treatment with energy)
- Where
- 2 sites in Canada
- Volunteers
- 31 people
- Sponsor
- Miramar Labs
Hyperhidrosis
Hyperhydrosis Treatment Using Botulinum Toxin
The purpose of this study is to describe two safe and reproducible techniques for the treatment of hyperhidrosis using botulinum toxin.
- Trial name
- NCT03816046
- Testing
- botulinum toxin A
- Where
- Lebanon
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- St Joseph University, Beirut, Lebanon
Chronic Heart Failure
Effect of Enhanced Sweat Rate on the Safety and Edema Status of Chronic Edematous Patients
The purpose of this study is to demonstrate safety and performance of AquaPass System for enhancing fluid transfer through the skin, by increased sweat rate, in edematous patients.
- Trial name
- NCT04578353
- Testing
- The AquaPass System
- Where
- Israel
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- AquaPass Medical Ltd.
Hyperhidrosis, Muscle Spasticity
Safety and Efficacy of BOTOX® (Botulinum Toxin Type A) in Korea
This post marketing surveillance study in Korea will evaluate the safety and efficacy of BOTOX (botulinum toxin Type A) in patients who receive treatment according to standard of care for primary axillary hyperhidrosis, focal…
- Conditions
- Hyperhidrosis, Muscle Spasticity, Glabellar Lines
- Trial name
- NCT02043145
- Testing
- botulinum toxin Type A
- Where
- South Korea
- Volunteers
- 727 people
- Sponsor
- Allergan
Psoriasis, Hidradenitis
Patients With Hidradenitis vs Patients With Psoriasis: Psychological Impact
The aim of this study is to evaluate the psychological impact of psoriasis or hidradenitis suppurativa on patients, in order to compare both pathologies.
- Trial name
- NCT02999698
- Testing
- Observational
- Volunteers
- 100 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Hidradenitis Suppurativa
A Study of Eltrekibart (LY3041658) in Adult Participants With Moderate to Severe Hidradenitis Suppurativa
This study aims to find the appropriately safe and effective dose and dosing frequency for eltrekibart in adults with moderate-to-severe hidradenitis suppurativa (HS) for further clinical development.
- Trial name
- NCT06046729
- Testing
- Eltrekibart
- Where
- 74 sites in United States, Australia and 4 more
- Volunteers
- 352 people
- Sponsor
- Eli Lilly and Company
Rheumatoid Arthritis (RA), Hidradenitis Suppurativa (HS)
A Long-Term Follow-Up Observational Study to Evaluate Safety in Subjects Who Have Received a Gene-Modified Regulatory T Cell (Treg) Therapeutic
To assess the emergence, type, severity, and potential causality of delayed adverse events following administration of a gene-modified Treg therapeutic.
- Trial name
- NCT07123038
- Testing
- Long Term Safety Monitoring Procedures
- Where
- 10 sites in United States
- Volunteers
- 36 people
- Sponsor
- Sonoma Biotherapeutics, Inc.
Hot Flushes, Night Sweats
Progesterone for Perimenopausal Night Sweats
The purpose of this study is to test whether a oral micronized progesterone reduces the Vasomotor Symptom Score comprised of the number and severity of hot flushes and night sweats in perimenopausal women.
- Trial name
- NCT01464697
- Testing
- Oral micronized progesterone
- Where
- Canada
- Volunteers
- 249 people
- Sponsor
- University of British Columbia
Hidradenitis Suppurativa (HS), Skin Inflammation
Molecular Evaluation of TAAR1 and JAK/STAT Pathway in Hidradenitis Suppurativa
This observational translational study aims to investigate gene and protein expression in lesional and perilesional skin of patients with Hidradenitis Suppurativa (HS) compared to controls.
- Trial name
- NCT07278011
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Trakya University
Hidradenitis Suppurativa
Hidradenitis Suppurativa Study of Izokibep
Izokibep is a small protein molecule that acts as a selective, potent inhibitor of interleukin 17A, to which it binds with high affinity.
- Trial name
- NCT05905783
- Testing
- Izokibep
- Where
- 98 sites in United States, Canada and 6 more
- Volunteers
- 258 people
- Sponsor
- ACELYRIN Inc.
Hidradenitis Suppurativa
A Study to Investigate Efficacy and Safety With SAR445399 in Adult Participants With Moderate to Severe Hidradenitis Suppurativa
This is a multinational, randomized, double-blind, placebo-controlled, Phase 2, dose finding study to evaluate the efficacy and safety of different doses of SAR445399 in adult participants with moderate to severe hidradenitis…
- Trial name
- CLAROS (NCT07225569)
- Testing
- SAR445399
- Where
- 86 sites in United States, Argentina and 13 more
- Volunteers
- 144 people
- Sponsor
- Sanofi
Hidradenitis Suppurativa (HS)
Efficacy and Safety Study of Adalimumab in Treatment of Hidradenitis Suppurativa
A study to evaluate the safety and efficacy of treatment with adalimumab in adults with moderate to severe hidradenitis suppurativa (HS).
- Trial name
- PIONEER I (NCT01468207)
- Testing
- adalimumab
- Volunteers
- 307 people
- Sponsor
- AbbVie (prior sponsor, Abbott)