Clinical trials: Sympathetic Nervous System
Brachial Plexus Block, Horner Syndrome
The Effects of Horner's Syndrome Developing After Interscalene Brachial Plexus Block on Autonomic Nervous Activity
This study evaluates the effects of Horner's syndrome on cardiac autonomic nervous activity after interscalene brachial plexus block.
- Conditions
- Brachial Plexus Block, Horner Syndrome, Autonomic Imbalance
- Trial name
- NCT03514342
- Testing
- Interscalene brachial plexus block, 0.75% ropivacaine
- Where
- South Korea
- Volunteers
- 48 people
- Sponsor
- Daegu Catholic University Medical Center
Hypoglycemia
Hypoglycemia and Autonomic Nervous System Function
The goals of this proposal are to determine the effects of hypoglycemia on the autonomic nervous system.
- Trial name
- HypoANS (NCT01816893)
- Testing
- Hypoglycemic hyperinsulinemic clamp, Euglycemic hyperinsulinemic clamp
- Where
- 2 sites in United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Vasospasm, Cerebral, Aneurysmal Subarachnoid Hemorrhage
The Effect of Sympathetic Modulation on Cerebral Vasospasm Secondary to Aneurysmal Subarachnoid Hemorrhage
The purpose of the study is to see that in addition to existing therapy, how well an additional procedure named spinal cord stimulation might reduce blood vessel spasm from aneurysm rupture.
- Trial name
- NCT06443177
- Testing
- Vectris trial leads and stimulation
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Alabama at Birmingham
Autonomic Nervous System Diseases
Sympathetic-parasympathetic Ratio of Our Gaze
ABSTRACT BACKGROUND The existence of the retinohypothalamic pathway suggests that light may influence autonomic outflow activity.
- Trial name
- NCT03322904
- Testing
- iris photography
- Where
- Turkey (Türkiye)
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Kecioren Education and Training Hospital
Insulin Resistance, Autonomic Dysfunction
Role of Endothelin-1 Modulating Insulin-stimulated Blood Flow and Sympathetic Nervous System Activity in Obesity
The aim of this project is to determine role for ET-1 in individuals with obesity.
- Conditions
- Insulin Resistance, Autonomic Dysfunction, Obesity
- Trial name
- NCT05518422
- Testing
- Hyperinsulinemic, euglycemic infusion
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Hypertension, Cardiovascular Diseases
Sympathetic Activity in Post-injury Outcomes: Impact on Sleep and caRdiovascular Health InvesTigation
The goal of this observational study is to learn about the long-term health of United States military service members who were injured during combat.
- Conditions
- Hypertension, Cardiovascular Diseases, Sleep Disorder, Arrythmia
- Trial name
- SPIRIT (NCT05971433)
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Uniformed Services University of the Health Sciences
Health Care Acceptor
Comparative Effects of the Neurodynamic Slider and Tensioner Mobilisation Techniques on Sympathetic Nervous System Function: A Randomised Controlled Trial
In accordance with an independently matched group design methodology, 90 healthy volunteers (aged 18 to 40) were enlisted and randomly assigned to one of three experimental groups (sliding, tension, or control groups).
- Trial name
- NCT06098131
- Testing
- Neurodynamic
- Where
- Cyprus
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- European University Cyprus
Temporal Lobe Epilepsy
Autonomic Dysfunction in Temporal Lobe Epilepsy and SUDEP
The study aimed at detection of autonomic dysfunction among cases with temporal lobe epilepsy; using different electrophysiological techniques.
- Trial name
- NCT06269822
- Testing
- Sympathetic skin response, heart rate variability test, quantitative EEG
- Where
- Egypt
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Cairo University
Down Syndrome, Autonomic Dysfunction
Exploring Sympathetic Nervous System Function in Individuals With Down Syndrome
Down syndrome (DS), the most common genetic cause of intellectual disability, is associated with widespread organ dysfunction, including abnormalities in the autonomic nervous system (ANS).
- Trial name
- DIVE (NCT07238465)
- Testing
- Cold Stress, Maximal Dynamic Exercise, Isometric Handgrip Exercise with Post-Exercise Muscle Ischemia
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Cardiomyopathy, Dilated, Tachycardia, Ventricular
The Leiden Nonischemic Cardiomyopathy Study
Rationale: Sudden cardiac death, mainly caused by ventricular arrhythmias (VA), is a major cause of morbidity and mortality in non-ischemic cardiomyopathy (NICM). Therapies that effectively prevent VA are lacking.
- Conditions
- Cardiomyopathy, Dilated, Tachycardia, Ventricular, Ventricular Fibrillation
- Trial name
- NCT01940081
- Testing
- Transthoracic echocardiography, Exercise test, 24-hour Holter electrocardiogram
- Where
- Netherlands
- Volunteers
- 148 people
- Sponsor
- Leiden University Medical Center
Complex Regional Pain Syndrome Type I of the Upper Limb
Single-port Thoracoscopic Sympathicotomy in Complex Regional Pain Syndrome Type I (CRPS)
Background of the study: CRPS type-1 is a pain syndrome that usually develops after an initiating noxious event (e.g. fracture) in an extremity.
- Trial name
- NCT01886625
- Testing
- unilateral single-port VATS sympathicotomy
- Where
- Netherlands
- Sponsor
- University of Groningen
Neck Pain
The Effects of Spinal Mobilizations on Neck Pain and Sympathetic Nervous System Activity in People With Neck Pain
This study investigates the effects of spinal mobilizations on neck symptoms and sympathetic nervous system activity in people with neck pain.
- Trial name
- NCT03507920
- Testing
- Neck passive mobilizations, Manual contact
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- King's College London
Obesity, Type 2 Diabetes Mellitus
Brown Adipose Tissue and Body Mass Index
In this study the investigators aim to investigate whether the sympathetic stimulation of BAT, as assessed with a 123I-metaiodobenzylguanidine single-photon emission computed tomography computed tomography scan, differs between…
- Trial name
- NCT02173834
- Testing
- 18F- fluorodeoxyglucose-positron emission tomography Computed Tomography scan and 123I-metaiodobenzylguanidine-single-photon emission computed tomography scan
- Where
- Netherlands
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Uncontrolled Hypertension
Renal Denervation in Patients With Uncontrolled Hypertension (Symplicity HTN-2)
An international, multi-center, prospective, randomized, controlled study of the safety and effectiveness of renal denervation in patients with uncontrolled hypertension.
- Trial name
- HTN-2 (NCT00888433)
- Testing
- Renal Denervation (Symplicity® Renal Denervation System)
- Where
- 20 sites in Australia, Austria and 8 more
- Volunteers
- 106 people
- Sponsor
- Medtronic Vascular
Systolic Heart Failure, Beta-blockers Intolerance
Surgical Sympathetic Blockade in Heart Failure
The investigators sought to evaluate the feasibility and safety of surgical sympathetic blockade in systolic heart failure patients and secondary to assess its cardiovascular consequences.
- Conditions
- Systolic Heart Failure, Beta-blockers Intolerance, Beta-blockers Resistance
- Trial name
- SymBlock (NCT01224899)
- Testing
- Left cervico-thoracic sympathetic blockade
- Where
- Brazil
- Volunteers
- 15 people
- Sponsor
- University of Sao Paulo
Uveitis, Intermediate Uveitis
Safety Study of Suprachoroidal Triamcinolone Acetonide Via Microneedle to Treat Uveitis
This study is designed to determine the safety and tolerability of a single microinjection of triamcinolone acetonide (TRIESENCE®) into the suprachoroidal space (SCS) of patients who have non-infectious uveitis.
- Conditions
- Uveitis, Intermediate Uveitis, Posterior Uveitis, Panuveitis
- Trial name
- NCT01789320
- Testing
- triamcinolone acetonide (Triesence®)
- Where
- 3 sites in United States
- Volunteers
- 11 people
- Sponsor
- Clearside Biomedical, Inc.
Complex Regional Pain Syndrome (CRPS), Shoulder Hand Syndrome
Effects of Motor Imagery Technique With and Without Virtual Reality on Pain Intensity ,Functional Disability and Quality of Life in Patient With Post Stroke Shoulder Hand Syndrome
the current study is a randomized controlled trial comparing the effectiveness of motor imagery techanique with and without virtual reality on pain intensity , functional disability and quality of life for individual with post…
- Trial name
- VR-SHS (NCT07610889)
- Testing
- motor imagery with virtual reality, motor imagery alone
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Green International University
Hypertension
Sympathetic Activity and Renal Denervation
Primary hypothesis: Catheter-based renal denervation reduces central sympathetic activation in patients with refractory hypertension. Secondary hypotheses: 1.
- Trial name
- ReD (NCT01355055)
- Where
- Germany
- Volunteers
- 26 people
- Sponsor
- Hannover Medical School
Shoulder-hand Syndrome
Acupuncture for Post-stroke Shoulder-hand Syndrome
Shoulder-hand syndrome，a common complication of stroke patient，which is an important factor of limb function recovery.This research aims to observe the effect and safety of Acupuncture and Traditional Chinese medicine Combined…
- Trial name
- NCT02011854
- Testing
- rehabilitation, Acupuncture
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Zouqin Huang
Hypertension
Effects of Thiazide Diuretics on Sympathetic Nervous System in Hypertension
Thiazide medications are often prescribed for individuals with high blood pressure, but research has shown that they may increase an individual's risk of developing diabetes.
- Trial name
- NCT00353652
- Testing
- Study#1: chlorthalidone (CTD), titrated dose, Study #1: spironolactone (SP), titrated dose, Study# 2 chlorthalidone (CTD), fixed dose
- Where
- 2 sites in United States
- Volunteers
- 166 people
- Sponsor
- University of Texas Southwestern Medical Center