Clinical trials: Symptom
Gastroparesis Like Symptoms
Neuromodulation With Percutaneous Electrical Nerve Field Stimulation
The IB-Stim is the first device to be approved by the Food and Drug Administration (FDA) for the treatment of functional abdominal pain in adolescents aged 11-18 with IBS.
- Trial name
- NCT07492108
- Testing
- Activated IB-Stim Device, Inactivated IB-Stim Device
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- The Cleveland Clinic
Long COVID Symptoms
Using Enhanced External Counterpulsation to Recover Cardiovascular Function for Patient of Chronic Diseases
The goal of this clinical trial is to learn whether enhanced external counterpulsation (EECP) therapy can improve cardiopulmonary function and symptoms in adults with long COVID.
- Trial name
- NCT07492953
- Testing
- enhanced external counterpulsation
- Where
- Taiwan
- Volunteers
- 10 people
- Sponsor
- National Defense Medical Center, Taiwan
Psoriasis, Depressive Symptoms
Smart Phone Delivered Cognitive Behavioral Therapy for Adults With Psoriasis and Co-Morbid Depression Symptoms
A single arm, pilot study in which all eligible participants will be enrolled in an 8-week coach-guided smartphone delivered CBT program. The full duration of the program, with follow-up interview, will be 9 weeks.
- Trial name
- NCT06216691
- Testing
- Coach-guided smartphone delivered CBT program.
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Brigham and Women's Hospital
BPH (Benign Prostatic Hyperplasia), Lower Urinary Track Symptoms
New Treatment Strategies and Epigenetic Biomarker for Management of Benign Prostatic Hyperplasia
SRD5A2 is a critical enzyme for prostatic development and growth, and the SRD5A2 inhibitor, finasteride, is used to treat benign prostatic hyperplasia (BPH).
- Trial name
- NCT06944145
- Testing
- raloxifene, Finasteride
- Where
- United States
- Volunteers
- 242 people
- Sponsor
- Beth Israel Deaconess Medical Center
Post-COVID-19 Condition, Post-COVID Condition
Expanded Access Use of Human Umbilical Cord Blood (REGENECYTE) Infusion in Patients With Chronic Fatigue of Post-COVID Condition
REGENECYTE® (HPC, Cord Blood (Hematopoietic Progenitor Cell, Cord Blood)) for treatment in patients with post-COVID.
- Conditions
- Post-COVID-19 Condition, Post-COVID Condition, Post-COVID Syndrome, Long COVID
- Trial name
- NCT07332338
- Testing
- REGENECYTE®
- Where
- 2 sites in United States
- Sponsor
- StemCyte, Inc.
PTSD, Trauma-related Mental Health Symptoms
Integrative Bilateral Cervical Sympathetic Blocks for Trauma-Related Symptoms in Special Operations Veterans: A Prospective Case Series
This study prospectively evaluates the effects of Integrative Bilateral Cervical Sympathetic Block (BCSB) on trauma-related symptoms in Special Operations Veterans, comparing outcomes in those receiving BCSB alone versus BCSB…
- Conditions
- PTSD, Trauma-related Mental Health Symptoms, Moral Injury, Anxiety
- Trial name
- NCT07473505
- Testing
- stellate ganglion block with 0.5% ropivacaine
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Reset Medical and Wellness Center
Psychoneurological Symptom Cluster(Pain, Insomnia, Anxiety, Fatigue, Depression, Subjective Cognitive Decline), Pain
Effect of Acupuncture on Psychoneurological Symptom Cluster in Breast Cancer Survivors
This clinical trial aims to assess whether electroacupuncture (EA) can alleviate the psychoneurological symptom cluster (including pain, fatigue, insomnia, anxiety, depression and subjective cognitive decline) in breast cancer…
- Conditions
- Psychoneurological Symptom Cluster(Pain, Insomnia, Anxiety, Fatigue, Depression, Subjective Cognitive Decline), Pain, Insomnia, Anxiety
- Trial name
- NCT07481903
- Testing
- electroacupuncture
- Where
- 6 sites in China
- Volunteers
- 228 people
- Sponsor
- First Teaching Hospital of Tianjin University of Traditional Chinese Medicine
Somatic Symptom Disorder
Use Repetitive Transcranial Magnetic Stimulation to Treat Somatic Symptom Disorder
This is a randomized double-blind sham-controlled crossover study; the interventions are high-frequency rTMS stimulation on left DLPFC and sham control. The study population is the patient with somatic symptom disorder.
- Trial name
- NCT05161819
- Testing
- Repetitive transcranial magnetic stimulation
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- National Taiwan University Hospital
Psychosomatic Symptoms, Temporomandibular Disorder (TMD)
Psychosomatic Symptoms in Patients With Myofascial Pain and Temporomandibular Joint Dysfunction
Temporomandibular joint disorder poses an intricate etiology. Biomechanical, neuromuscular and psychosocial factors may contribute to the disorder among which psychological and psychosocial disturbances have shown strong direct…
- Trial name
- Psychosomatic (NCT07385781)
- Testing
- Casr
- Where
- Pakistan
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Bahria University
Adult Congenital Heart Disease, Symptom Clusters
AI-Enabled Frailty Risk Prediction in Adult Congenital Heart Disease
The goal of this three-year mixed-methods observational study with an embedded randomized controlled trial is to develop and validate a frailty risk prediction model and evaluate an artificial intelligence-based voice emotion…
- Conditions
- Adult Congenital Heart Disease, Symptom Clusters, Frailty, Risk Prediction Model
- Trial name
- NCT07479654
- Testing
- AI-Based Voice Emotion Detection-Guided Counselling, Usual Care (Control)
- Volunteers
- 410 people
- Sponsor
- Mackay Memorial Hospital
Obsessive-Compulsive Symptom
Efficacy of Intensified Transcranial Direct Current Stimulation in Obsessive-compulsive Disorder
This is a randomized, double-blind, parallel-group, sham-controlled trial that aims to investigate the effectiveness of transcranial direct current stimulation (TDCS) on improving symptoms, quality of life, depression, and…
- Trial name
- NCT05501132
- Testing
- transcranial direct current stimulation
- Where
- Iran
- Volunteers
- 42 people
- Sponsor
- The National Brain Mapping Laboratory (NBML)
Benign Prostatic Hyperplasia, Lower Urinary Tract Symptoms
Silodosin vs Tamsulosin for LUTS Due to BPH: A Randomized Crossover Trial
The goal of this randomized crossover clinical trial is to compare the efficacy and safety of Silodosin versus Tamsulosin in patients with moderate to severe lower urinary tract symptoms due to Benign Prostatic Hyperplasia.
- Trial name
- NCT07467343
- Testing
- Silodosin, Tamsulosin
- Where
- Egypt
- Volunteers
- 140 people
- Sponsor
- Ain Shams University
Visual Rehabilitation, Visual Impairment, Autism Spectrum Disorder, Developmental Disabilities, Intellectual Disability, Behavioral Symptoms
Evaluation of a Program to Enhance Ophthalmic Compliance in Children and Adolescents With Special Needs
The goal of this clinical trial is to learn about the effects of the structured program incorporating contextual, behavioral, and cognitive strategies to improve compliance of children and adolescents with special needs during…
- Trial name
- NCT06717282
- Testing
- visual rehabilitation for ophthalmic compliance, Using contextual, behavioral, and cognitive-based stragegies to develop training programs
- Where
- Taiwan
- Volunteers
- 20 people
- Sponsor
- National Taiwan University Hospital
IBD (Inflammatory Bowel Disease), IBS (Irritable Bowel Syndrome)
Specimen and Data Collection for a Novel Biomarker Combination for the Differential Diagnosis of Inflammatory Bowel Disease and Irritable Bowel Syndrome.
This study will evaluate how well the a new stool test can distinguish inflammatory bowel disease (IBD) from non-IBD conditions compared with standard calprotectin testing and colonoscopy findings.
- Conditions
- IBD (Inflammatory Bowel Disease), IBS (Irritable Bowel Syndrome), Gastrointestinal Symptoms
- Trial name
- COMBI (NCT07471490)
- Where
- 2 sites in United States, Italy
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- DiaSorin Inc.
Lower Urinary Tract Symptoms
A Pilot Study to Assess Effects of Self-Administered Nitrous Oxide (SANO) on Urodynamic Study (UDS) Parameters
A urodynamic study (UDS) is a common procedure done to learn more about the cause of urinary symptoms. For some patients, UDS can be associated with anxiety or discomfort.
- Trial name
- NCT05883332
- Testing
- Self-Administered Nitrous Oxide, Oxygen
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Resting Heart Rate, Blood Glucose Control
Assessing the Effects of Cool Roofs on Indoor Environments and Health in Colima, Mexico
Ambient air temperatures in Mexico have broken record highs in 2024. Solutions are needed to build heat resilience in communities and adapt to increasing heat from climate change.
- Conditions
- Resting Heart Rate, Blood Glucose Control, Depression, Heat-related Symptoms
- Trial name
- REFLECT (NCT06834893)
- Testing
- Cool roof
- Where
- Mexico
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Aditi Bunker
Psychological Distress, Anxiety Symptoms
Exer-WAPA Project: Physical Exercise on Women's Affective and Physical HeAlth
The Physical Exercise on Women's Affective and Physical HeAlth (Exer-WAPA) project is a randomized controlled trial (RCT) designed to evaluate the effects of a supervised, group-based exercise program incorporating…
- Conditions
- Psychological Distress, Anxiety Symptoms, Depression Symptoms
- Trial name
- Exer-WAPA (NCT07466979)
- Testing
- Supervised Concurrent Exercise (Exer-WAPA)
- Where
- Spain
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Universidad de Granada
Respiratory Disease, Gastrointestinal Diseases and Symptom
12 Steps of a Modified Handwashing Program on Health Outcomes and School Absenteeism
The goal of this clinical trial is to assess whether providing hand and respiratory hygiene interventions in primary school children reduces the incidence rate of absence episodes due to illness in children during an academic…
- Trial name
- Hand hygiene (NCT07467902)
- Testing
- Hand Hygiene Education Program
- Where
- Iraq
- Volunteers
- 802 people, healthy volunteers welcome
- Sponsor
- Hawler Medical University
Fatigue, Fatigue Post Viral
Characterization, Treatment, and Long-term Follow-up of Fatigued Patients in Primary Care
The overarching purpose of this project is to further the understanding of fatigue as a symptom in primary care patients, and to build evidence for a highly accessible treatment targeting fatigue that can be readily implemented…
- Conditions
- Fatigue, Fatigue Post Viral, Exhaustion Disorder, Fatigue Symptom
- Trial name
- iFAS (NCT06786832)
- Testing
- Cognitive behavioral therapy for persistent fatigue, Care as usual
- Where
- Sweden
- Volunteers
- 190 people
- Sponsor
- Karolinska Institutet
TRX Exercise, Bowel Habits
TRX Exercises and Gastrointestinal Health in Swimmers
Purpose Exercise-related gastrointestinal complaints are frequently reported in young athletes; however, evidence regarding the effects of resistance-based training modalities on bowel habits is limited.
- Conditions
- TRX Exercise, Bowel Habits, Gastrointestinal Symptoms, Swimming
- Trial name
- NCT07464509
- Testing
- Exercise, Randomized Controlled Trial
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Aksaray University