Clinical trials: Symptom
Copd
Assessment of Trace Elements, Systemic Inflammation and Electrolytes
COPD is one of the most common causes of health problems worldwide. It is a disease that is associated with several systemic features that affect its morbidity and mortality.
- Trial name
- NCT05718453
- Testing
- Laboratory Tests
- Where
- Egypt
- Volunteers
- 140 people
- Sponsor
- Egymedicalpedia
Patients Hospitalized in the Hospices Civils of Lyon, COVID-19 Disease
Measurement of the Efficacy of MORPHINE in the Early Management of Dyspnea in COVID-19 Positive Patients
Morphine is used in the treatment of dyspnea and polypnea with a proven benefit on the improvement of these symptoms, both etiologically and symptomatically.
- Conditions
- Patients Hospitalized in the Hospices Civils of Lyon, COVID-19 Disease, Moderate to Severe Dyspnea, Without Resuscitation Objective Management
- Trial name
- CODYS (NCT04522037)
- Testing
- No intervention / Compare the difference in respiratory rate between H0 and H12 of the initiation of morphine between the control and interventional groups
- Where
- 3 sites in France
- Volunteers
- 200 people
- Sponsor
- Hospices Civils de Lyon
Chronic Hepatitis C
Real-world Effectiveness and Safety of Treatment With DAAs in Patients With CHC(Chronic Hepatitis C)
This is a multi-center, open-label clinical study. This study was aimed to assess the real-world effectiveness and safety of treatment with listed DAAs in patients with CHC and cirrhosis in Southern area of China.
- Trial name
- NCT03887637
- Testing
- DAAs
- Volunteers
- 180 people
- Sponsor
- Third Affiliated Hospital, Sun Yat-Sen University
Weight Loss, Obesity
Using Social Incentives and Gamification for Weight Loss Promotion
This is a 36-week, three-arm randomized, controlled trial using a team-based model to compare two weight loss programs to control.
- Conditions
- Weight Loss, Obesity, Physical Activity
- Trial name
- NCT02564445
- Testing
- Gamification, Share Data with PCP, Feedback on weight
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Eating Disorders, Maladaptive Personality Trait
MICBT for Non-underweight Adults With Eating Disorders
Eating disorders (ED) are severe but treatable conditions, but there are large margin for improvements in terms of efficacy and adherence.
- Conditions
- Eating Disorders, Maladaptive Personality Trait, Emotion Regulation, Personality
- Trial name
- MICBT-ED (NCT05503745)
- Testing
- CBT-F+MIT, CBT-E
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Centro Trattamento Integrato: Disturbi Alimentari e Obesita
Lower Urinary Track Symptoms
Urinary CA19-9 Level in the Differential Diagnosis of Neurogenic and Non-Neurogenic Lower Urinary Tract Dysfunction in Children
It has been shown in the literature that urinary CA19-9 levels are associated with the degree of hydronephrosis and the anteroposterior diameter of the renal pelvis.
- Trial name
- NCT06785545
- Testing
- CA19-9
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Marmara University
Primary Immune Thrombocytopenia
Safety and Efficacy Study of PF-06835375 in Primary Immune Thrombocytopenia
This is a Phase 2, open-label, multicenter, multiple subcutaneous injection, safety and efficacy study of PF-06835375 in adult participants with primary immune thrombocytopenia (ITP).
- Trial name
- NCT05070845
- Testing
- PF-06835375
- Where
- 24 sites in United States, Australia and 5 more
- Volunteers
- 61 people
- Sponsor
- Pfizer
Neurotoxicity, Pain
Lamotrigine in Treating Peripheral Neuropathy Caused by Chemotherapy in Patients With Cancer
RATIONALE: Lamotrigine may be effective in reducing pain, numbness, tingling, and other symptoms of peripheral neuropathy. It is not yet known whether lamotrigine is effective in treating peripheral neuropathy caused by…
- Conditions
- Neurotoxicity, Pain, Unspecified Adult Solid Tumor, Protocol Specific
- Trial name
- NCT00068445
- Testing
- lamotrigine
- Where
- 23 sites in United States
- Volunteers
- 131 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Hepatitis C, Chronic
A Study of PEGASYS (Peginterferon Alfa-2a (40KD)) Plus Ribavirin in Hemophiliac Patients With Chronic Hepatitis C.
This study will evaluate the efficacy and safety of PEGASYS plus ribavirin in male patients with hemophilia A and chronic hepatitis C. All patients will receive PEGASYS 180 micrograms s.c. weekly plus ribavirin 1000-1200mg p.o.
- Trial name
- NCT00475072
- Testing
- peginterferon alfa-2a [Pegasys], ribavirin
- Where
- Mexico
- Volunteers
- 14 people
- Sponsor
- Hoffmann-La Roche
Retinopathy of Prematurity, Retinal Detachment
Efficient Study of ACULAR in Inhibiting Proliferative Retinopathy in Prematurity
The purpose of this study is to test whether ACULAR, a nonsteroidal anti-inflammatory eye drop medication, can prevent the development of retinopathy of prematurity (ROP) and/ or decrease its severity.In this study ACULAR will be…
- Conditions
- Retinopathy of Prematurity, Retinal Detachment, Blindness
- Trial name
- ROP (NCT00634972)
- Testing
- ACULAR, REFRESH TEARS
- Where
- United States
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- University of South Alabama
Lymphoma, B-Cell, Leukemia, B-Cell
CD19-targeted CAR-T Cell Therapy for MRD+ B-cell Malignancies After Autologous Stem Cell Transplantation
The main purpose of this study is to explore the efficacy of CD19-targeted CAR-T cell therapy for minimal residual disease (MRD) in B-cell Malignancies after autologous stem cell transplantation.
- Conditions
- Lymphoma, B-Cell, Leukemia, B-Cell, Minimal Disease, Residual
- Trial name
- NCT03564977
- Testing
- CD19-targeted CAR-T cells
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Qingdao Central Hospital
Implantable Cardioverter Defibrillator (ICD), Aromatherapy
Implantable Cardioverter Defibrillator (ICD) Patients and Inhalation Aromatherapy
The effective management of anxiety and fatigue, which lead to negative physical, social, and psychological impacts and increase treatment costs in individuals with implanted cardioverter-defibrillators (ICD), is of great…
- Conditions
- Implantable Cardioverter Defibrillator (ICD), Aromatherapy, Anxiety, Fatigue Symptom
- Trial name
- ICD (NCT06874777)
- Testing
- Aromatherapy group
- Where
- Turkey (Türkiye)
- Volunteers
- 86 people
- Sponsor
- TC Erciyes University
Migraine
A Study of LY2951742 (Galcanezumab) in Japanese Participants With Episodic Migraine
The main purpose of this study is to determine the efficacy of the study drug Galcanezumab in Japanese participants with episodic migraine.
- Trial name
- NCT02959177
- Testing
- Galcanezumab
- Where
- 47 sites in Japan
- Volunteers
- 459 people
- Sponsor
- Eli Lilly and Company
HIV (Human Immunodeficiency Virus), Chlamydia
Evaluation of Free STI Testing Pilot Projects in Lucerne and Zurich, Switzerland
The main goal of the observational study is to evaluate participants' satisfaction with free HIV and sexually transmitted infection (STI) testing and counselling offered by the cities of Lucerne and Zurich, Switzerland to young…
- Conditions
- HIV (Human Immunodeficiency Virus), Chlamydia, Gonorrhea, Syphilis
- Trial name
- feSTI (NCT07516912)
- Volunteers
- 1,800 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Enuresis, Nocturnal
The Effect of Selecting Treatment With Desmopressin or Alarm to Children With Enuresis Based on Home Recordings.
The aim of this study is to investigate the importance of clinical characterization of children with monosymptomatic nocturnal enuresis (MNE) in order to improve treatment efficacy.
- Trial name
- DRYCHILD (NCT03389412)
- Testing
- Desmopressin, Conditional alarm
- Where
- 6 sites in Belgium, China and 2 more
- Volunteers
- 324 people
- Sponsor
- University of Aarhus
Acute Myeloid Leukemia With Gene Mutations
Expanded Treatment Protocol for Adults With FLT3-ITD Mutated Relapsed or Refractory Acute Myeloid Leukemia (AML) to Receive Quizartinib
An expanded access program (EAP): Allows doctors to give medicine to patients, Before it is approved by health authorities. This EAP is for: Quizartinib Patients with FLT3-ITD mutated AML, AML that has come back, or Is resistant…
- Trial name
- NCT03746912
- Testing
- Quizartinib Dihydrochloride
- Sponsor
- Daiichi Sankyo
Spinal Cord Injuries, Neurogenic Bladder
Intravesical Lactobacillus to Reduce Urinary Symptoms After Spinal Cord Injury
The objectives of the proposed research among this population are: 1) to define clinically meaningful change (i.e. differentiating states of health and illness) with respect to urinary symptoms, urine inflammation, cultivable…
- Trial name
- NCT04373512
- Testing
- Culturelle 10 Billion CFU Capsule (2 doses), Culturelle 10 Billion CFU Capsule (4 doses)
- Where
- United States
- Volunteers
- 182 people
- Sponsor
- Medstar Health Research Institute
Anorexia Nervosa, Gut Microbiota
Effect of Treatment With Butyric Acid in Anorexia Nervosa
This clinical trial aims to evaluate the therapeutic potential of oral butyric acid supplementation in individuals with anorexia nervosa (AN).
- Conditions
- Anorexia Nervosa, Gut Microbiota, Weight Trajectory
- Trial name
- AN-BUTIX (NCT07289581)
- Testing
- Dietary Supplement: Butyric Acid
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Azienda Ospedaliero-Universitaria Careggi
Cardiogenic Shock
ExtraCorporeal Membrane Oxygenation in the Therapy of Cardiogenic Shock
Eligible patients with severe cardiogenic shock will be randomized to one of the two arms: immediate ECMO therapy or early conservative therapy.
- Trial name
- ECMO-CS (NCT02301819)
- Testing
- Veno-arterial extracorporeal membrane oxygenation (ECMO), Early conservative therapy according to standard practice
- Where
- 4 sites in Czechia
- Volunteers
- 122 people
- Sponsor
- Na Homolce Hospital
Halitosis
Photodynamic Therapy With Red Leds in Microorganisms Related to Halitosis
Halitosis is the term used to describe any unpleasant odor relative to expired air regardless of its source. The prevalence of halitosis in the population is approximately 30%, of which 80-90% of the cases originate in the oral…
- Trial name
- halitosis (NCT03656419)
- Testing
- photodynamic therapy, Tongue scraper
- Where
- Brazil
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
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