Clinical trials: Symptom Monitoring
Coronary Artery Bypass Graft Redo, Heart Valve Diseases
SONOlysis in Risk REduction of Symptomatic and Silent Brain infarCtions dUring Cardiac surgEry
The aim of the project is to demonstrate a fibrinolytic effect of sonothrombolysis (continual transcranial Doppler monitoring) using 2 MHz diagnostic probe on the reduction of risk of brain infarctions due to the activation of…
- Trial name
- SONORESCUE (NCT01591018)
- Testing
- sonolysis, cardiac surgery
- Where
- Czechia
- Volunteers
- 120 people
- Sponsor
- University Hospital Ostrava
Hypoxia
Cerebral Oximetry in Single Lung Ventilation Thoracic Surgery
This is a prospective, randomized controlled pilot study of cerebral oximetry use in elderly patients undergoing thoracic surgical procedures that require the use of single lung ventilation.
- Trial name
- NCT01866657
- Testing
- Vasoconstrictor Agents, Head/neck repositioning, Increase ETCO2
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- University Hospitals Cleveland Medical Center
Stroke, Ischemic Stroke
Safety Study of Post Intravenous tPA Monitoring in Ischemic Stroke
Intravenous (IV) tissue plasminogen activator (tPA) is the only FDA-approved therapy for treatment of acute ischemic stroke. In the United States, IV tPA is typically administered in the Emergency Department (ED) for patients…
- Trial name
- OPTIMIST (NCT02039375)
- Testing
- "Hopkins" post tPA for ischemic stroke monitoring protocol
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Johns Hopkins University
Asthma
Automated Device for Asthma Monitoring
This study will examine an innovative strategy to monitor asthma symptoms by using existing technology to develop a non-invasive device for monitoring asthma symptoms in adolescents.
- Trial name
- ADAM (NCT01696357)
- Testing
- Automated Device for Asthma Monitoring (ADAM)
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Cardiovascular Disease
Implementation of Practice Standards for ECG Monitoring
The purpose of this study is to test the effect of implementing new practice standards for electrocardiographic (ECG) monitoring on nurses' knowledge and skills, quality of care, and patient outcomes.
- Trial name
- PULSE (NCT01269736)
- Testing
- Education
- Where
- 16 sites in United States, Canada and 1 more
- Volunteers
- 92,057 people, healthy volunteers welcome
- Sponsor
- Yale University
Fluid Overload, Fluid Loss
Atrial Natriuretic Peptide in Assessing Fluid Status
Biomarkers can play a significant role in fluid status assessment intraoperatively.
- Conditions
- Fluid Overload, Fluid Loss, Volume Overload, Cardiac Disease
- Trial name
- NCT05070819
- Testing
- pro-ANP
- Where
- Russia
- Volunteers
- 30 people
- Sponsor
- Petrovsky National Research Centre of Surgery
Dementia, Staff Attitude
Speeko for Elderspeak: A Self-Monitoring App to Improve Nursing Home Communication
This study will test feasibility and preliminary effects of an automated and performance-based feedback app (Speeko for Elderspeak) that detects and reports the use of diminutives (terms of endearment such as honey, dearie, and…
- Trial name
- NCT04064164
- Testing
- Speeko for Elderspeak
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Stroke
Long-term Cardiac Monitoring After Cryptogenic Stroke (CMACS)
Atrial fibrillation (AF) is a common and treatable cause of ischemic stroke, but it can be paroxysmal and asymptomatic, and therefore difficult to detect.
- Trial name
- CMACS (NCT00932425)
- Testing
- Cardionet Mobile Cardiac Outpatient Telemetry (MCOT)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of California, San Francisco
Cancer
Clinical Impact and Utility of Digital Health Solutions in Participants Receiving Systemic Treatment in Clinical Practice
This study will evaluate the clinical impact and utility of digital health solutions (DHS) on health outcomes and health-care resource utilization in people receiving systemic anti-cancer treatment (approved or non-approved) in…
- Trial name
- ORIGAMA (NCT05694013)
- Testing
- Roche DPM Module, Atezolizumab SC, Local SOC support
- Where
- 14 sites in Australia, Austria and 3 more
- Volunteers
- 49 people
- Sponsor
- Hoffmann-La Roche
Heart Failure, Congestive
Sensitivity of the InSync Sentry OptiVol Feature for the Prediction of Heart Failure
The SENSE-HF study is a prospective, observational, international multi-center study prospectively evaluating the sensitivity and positive predictive value of the OptiVol Fluid Trends data in predicting Heart Failure related…
- Trial name
- SENSE-HF (NCT00400985)
- Testing
- Implantable device: monitoring of intrathoracic impedance using the OptiVol diagnostic tool.
- Where
- 2 sites in Belgium, United Kingdom
- Volunteers
- 501 people
- Sponsor
- Medtronic Cardiac Rhythm and Heart Failure
Spine Diseases
Awakening in Spine Surgery: A Comparison Between Clinical Signs and Bispectral Index
BIS is one of several equipments used to monitor depth of anesthesia.Some studies found BIS can reduce total propofol dose when being used with target controlled infusion (TCI).The objective is to compare awakening time after…
- Trial name
- NCT02174913
- Testing
- bispectral index, Target controlled infusion of propofol, Fentanyl
- Where
- Thailand
- Volunteers
- 34 people
- Sponsor
- Mahidol University
Atrial Fibrillation, Heart Valve Diseases
Prolongation of the Interval Between Monitoring of Warfarin in Stable Patients
Patients with mechanical heart valve prosthesis or with irregular beat (atrial fibrillation) have a high risk of blood clot formation. Such clots can result in a stroke.
- Conditions
- Atrial Fibrillation, Heart Valve Diseases, Venous Thrombosis
- Trial name
- NCT00356759
- Where
- Canada
- Volunteers
- 250 people
- Sponsor
- Hamilton Health Sciences Corporation
Cirrhosis, Liver, Portal Hypertension
A Pilot Trial to Test the Feasibility of Utilizing Home Blood Pressure Monitoring to Optimize the Administration of Midodrine Among Decompensated Cirrhosis Patients
This is a randomized single-blind feasibility trial to test the utilization of home blood pressure devices to improve the clinical management of decompensated cirrhosis patients.
- Conditions
- Cirrhosis, Liver, Portal Hypertension, Ascites Hepatic
- Trial name
- WATCH (NCT05928624)
- Testing
- Withings Home Blood Pressure Device and Scale, Standard of Care
- Where
- United States
- Volunteers
- 69 people
- Sponsor
- University of California, San Francisco
Breast Cancer
Evaluation of Efficiency in Cancerology of New Technologies as Telemedicine and Conected Objects (e-DomSanté)
Observational study about patients treated for a metastasis breast cancer who live far from their comprehensive cancer center and followed by telemedicine, connected watches and patient-reported symptom monitoring.
- Trial name
- e-DomSanté (NCT03359759)
- Testing
- Conected objects
- Where
- France
- Volunteers
- 15 people
- Sponsor
- Institut Bergonié
Paroxysmal Supraventricular Tachycardia
Safety Study of Intranasal Etripamil for the Termination of Spontaneous Episodes of Paroxysmal Supraventricular Tachycardia (PSVT). NODE-302
The primary objective of this study is to evaluate the safety of etripamil nasal spray (NS) 70 mg when self-administered by patients with an episode of Paroxysmal Supraventricular Tachycardia in an outpatient setting (i.e.…
- Trial name
- NCT03635996
- Testing
- Etripamil NS 70 mg, Aptar Pharma Nasal Spray Bidose System
- Where
- 34 sites in United States, Canada
- Volunteers
- 169 people
- Sponsor
- Milestone Pharmaceuticals Inc.
Obesity, Cardiovascular Disease
IMPACT: Inactivity Monitoring and Physical Activity Controlled Trial
As individuals age, their physical activity decreases and sedentary time increases. Even small changes in these two behaviors can greatly decrease risks for several major health problems, including cardiovascular disease…
- Conditions
- Obesity, Cardiovascular Disease, Cancer, Diabetes
- Trial name
- IMPACT (NCT01869348)
- Testing
- Monitor intervention
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Residual Paralysis, Post Anesthesia
Best Management of Muscle Relaxation- Objective Monitoring
The purpose of this study is to demonstrate that the investigators can reduce residual paralysis to a very low incidence, and that the investigators can do this while preserving a role for the older and less expensive reversal…
- Trial name
- NCT03958201
- Testing
- Protocol for Management of Muscle Relaxation With Rocuronium Using Objective Monitoring and Reversal With Neostigmine or Sugammadex
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of Washington
Diagnosis, Dual (Psychiatry)
Dual Diagnosis Inpatients: Telephone Monitoring RCT to Improve Outcomes
This research program will improve the care and treatment outcomes of dually diagnosed veterans who receive inpatient psychiatry care, and decrease their use of VA inpatient mental health services.
- Trial name
- NCT01135420
- Testing
- Telephone Monitoring (TM) with Motivational Interviewing, Usual care
- Where
- 2 sites in United States
- Volunteers
- 406 people
- Sponsor
- VA Office of Research and Development
Gastroparesis
Clinical Management With SPM System and Validation of the SPM 5 Hour Cutoff in Patients With Symptoms of Gastroparesis
This protocol is designed to validate use of the SPM for diagnosis of delayed gastric emptying in patients with symptoms of gastroparesis and assess impact of a SmartPill study on patient management in the gastroparetic…
- Trial name
- NCT02022826
- Testing
- SmartPill Monitoring System
- Where
- 11 sites in United States
- Volunteers
- 167 people
- Sponsor
- Medtronic - MITG
Diabetes, Hypertension
Scripps Wired for Health Monitoring Study
People with chronic diseases such as diabetes, hypertension (high blood pressure) and cardiac (heart) arrhythmias tend to go to the doctor more often and have more tests done than those without those diseases.
- Conditions
- Diabetes, Hypertension, Cardiac Arrhythmia
- Trial name
- NCT01975428
- Testing
- DM Pgm + device, Control
- Where
- United States
- Volunteers
- 182 people
- Sponsor
- Scripps Translational Science Institute