Clinical trials: Symptomatic Irreversible Pulpitis and Post Operative Pain
Root Canal Sealers, Post Operative Pain
Evaluation of Post Obturation Pain Associated With Calcium Hydroxide-based Root Canal Sealers and Resin-based Root Canal Sealer: a Single Visit Root Canal Treatment
The objective of this study is to evaluate the post obturation pain associated with calcium hydroxide-based root canal sealer and resin-based root canal sealer after single visit root canal treatment following endodontic…
- Conditions
- Root Canal Sealers, Post Operative Pain, Irreversible Pulpitis
- Trial name
- NCT06798467
- Testing
- Endodontic sealer, post obturation pain
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Jinnah Sindh Medical University
Post Operative Pain, Acute, Irreversible Pulpitis
To Evaluate Post Operative Pain Using Two Different Kind of Sealers in Obturation of Teeth With Symptomatic Irreversible Pulpitis During Second Visit When the Patient is Painless
The goal of this randomized clinical trial is to evaluate pain after root canal treatment using two different kinds of sealers during obturation in 60 healthy , male and female patients ages between 18 to 40 years.
- Trial name
- NCT07266974
- Testing
- AH-Plus Epoxy Resin Sealer, bioceramic sealer
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Jaweria Gul Keyani
Postoperative Pain After Endodontic Treatment, Oral Health-Related Quality of Life
Effects of Different Root Canal Filling Materials and Irrigation Agitation Techniques on Postoperative Pain in Teeth With Irreversible Pulpitis: A Randomized Clinical Trial
This clinical study is designed to evaluate the effects of different irrigation agitation techniques and root canal sealers on postoperative pain and oral health-related quality of life in patients with symptomatic irreversible…
- Conditions
- Postoperative Pain After Endodontic Treatment, Oral Health-Related Quality of Life, Symptomatic Irreversible Pulpitis, Endodontic Treatment
- Trial name
- NCT07859384
- Testing
- XP-Endo Finisher, EDDY, Passive Ultrasonic Activation
- Where
- Turkey (Türkiye)
- Volunteers
- 324 people
- Sponsor
- Ankara University
Symptomatic Irreversible Pulpitis (SIP)
Effect of Preoperative Diclofenac Potassium Dose on Endodontic Pain
The aim of this study is to assess the effect of different doses of diclofenac potassium premedication (100mg vs 50mg) on anesthetic success of 4% articaine buccal infiltration and post-operative pain as compared to placebo in…
- Trial name
- NCT07743372
- Testing
- Diclofenac potassium 100mg, Diclofenac potassium 50mg
- Volunteers
- 90 people
- Sponsor
- Cairo University
Pain, Postoperative
Ibuprofen Versus Ibuprofen/Acetaminophen Postoperatively in Patients Needing Root Canal Therapy
Aim: The purpose of this study was to compare ibuprofen versus an ibuprofen/acetaminophen combination for postoperative pain control in patients requiring root canal treatment with a tooth that is painful to cold and biting.
- Trial name
- NCT03631433
- Testing
- Ibuprofen 600 mg, ibuprofen 600 mg and acetaminophen 650 mg
- Volunteers
- 102 people
- Sponsor
- Ohio State University
Pulpitis - Irreversible, Vitamin D Deficiency
Effect of Vitamin D on Postoperative Pain in Symptomatic Irreversible Pulpitis
Vitamin D deficiency (VDD) is a prevalent global health concern that has been linked to altered pain perception through its effects on inflammatory pathways, nociceptor activity, and neurotrophic signaling.
- Trial name
- NCT07579637
- Testing
- Vitamin D3
- Where
- Egypt
- Volunteers
- 54 people
- Sponsor
- Future University in Egypt
Symptomatic Irreversible Pulpitis
Comparative Evaluation of Postoperative Pain and Clinical Success
Sixty-three mandibular molars with vital pulp, symptomatic acute pain, and a Numerical Rating Scale (NRS) score of 7 or higher-requiring emergency treatment-were randomly allocated into three groups according to the preparation…
- Trial name
- NCT07133217
- Testing
- Root canal preparation with Hand Files (Dentsply Sirona), Root canal preparation with the WaveOne Gold file system (Dentsply Sirona, Ballaigues, Switzerland), Root canal preparation with the ProTaper Ultimate file system (Dentsply Sirona)
- Where
- Turkey (Türkiye)
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Ege University
Symptomatic Irreversible Pulpitis
Comparison of Post-Operative Pain Occurrence After Single Visit Root Canal Treatment
The goal of this clinical trial is to compare the post-operative pain occurrence after single visit root canal treatment using Two NiTi Rotary Files.
- Trial name
- NCT06777381
- Testing
- single visit root canal treatment using ProTaper Universal rotary system, single visit root canal treatment using M-Pro rotary system
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- National Research Centre, Egypt
Postoperative Pain
Comparative Evaluation of the Efficacy of Intraoral Cryotherapy Versus Intracanal Cryotherapy on Postoperative Pain
The aim of this study is to clinically compare the efficacy of intraoral cryotherapy versus intracanal cryotherapy after single visit root canal therapy in lower molars with irreversible pulpitis and symptomatic apical…
- Trial name
- NCT05041738
- Testing
- Intraoral Cryotherapy, Intracanal Cryotherapy
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Cairo University
Post-operative Pain, Irreversible Pulpitis
Relationship of Eye Colour With Anesthetic Success and Post-Operative Pain
Current evidence indicates that some phenotypic characteristics, such as eye or hair color, might be associated with the experience of pain.
- Trial name
- NCT06206304
- Testing
- Root canal therapy
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Mustafa Kemal University
Symptomatic Irreversible Pulpitis (SIP)
Postoperative Pain After Full Pulpotomy With TheraCal PT, Biodentin, and MTA
In this study, the researchers will evaluate the effect of three highly biocompatible materials-TheraCal PT (ThPT), Biodentin, and MTA-on postoperative pain in permanent teeth affected by deep caries and symptomatic irreversible…
- Trial name
- NCT06880471
- Testing
- TheraCal PT pulpotomy, MTA pulpotomy, Biodentine pulpotomy
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 51 people
- Sponsor
- Cumhuriyet University
Symptomatic Irreversible Pulpitis, Post Operative Pain
Effect of Preoperative Tramadol and Naproxen Sodium on Post Operative Pain
The goal of this clinical trial is to compare in Tramadol, Naproxen sodium and Placebo in participants presenting with irreversible pulpitis in their mandibular molar teeth.
- Trial name
- NCT05982392
- Testing
- Tramadol, Naproxen Sodium
- Where
- Pakistan
- Volunteers
- 139 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Anesthesia
Effect of Ibuprofen Sustained Release on Intraoperative and Postoperative Pain in Mandibular Molars
The study is conducted to evaluate the effect of Ibuprofen sustained release premedication on the success of buccal infiltration anaesthesia, intaroperative pain and post operative pain in mandibular molars with symptomatic…
- Trial name
- NCT05053009
- Testing
- Brufen Retard
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Cairo University
Evaluate Occlusal Reduction on Post-operative Pain, Teeth With Symptomatic Irreversible Pulpitis
Effect of Occlusal Reduction on Post-operative Pain
effect of occlusal reduction on post-operative pain is evaluated after single visit root canal treatment in upper and lower molar teeth in patients with sypmtomatic irreversible pulpitis and apical periondontis
- Conditions
- Evaluate Occlusal Reduction on Post-operative Pain, Teeth With Symptomatic Irreversible Pulpitis, Apical Periodontitis
- Trial name
- NCT03189771
- Testing
- occlusal surface reduction
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Cairo University
Symptomatic Irreversible Pulpitis
Postoperative Pain Intensity After Pulpotomy
Introduction: This study aimed to compare postoperative pain rates following sodium hypochlorite (NaOCl) and KTP laser-assisted pulpotomy treatments in permanent teeth with deep caries, and symptomatic irreversible pulpitis.
- Trial name
- NCT05424796
- Testing
- Physiological saline, Hemostasis and cavity disinfection with NaOCl, Hemostasis and cavity disinfection with KTP laser
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Cumhuriyet University
Pulpitis - Irreversible
Effect of Cryotreated Sodium Hypochlorite Irrigation at Different Consentrations in Mandibular First Molars
The goal of this clinical trial was to evaluate the effect of cryotreated sodium hypochlorite solution on the intensity of postoperative pain in root canal treatment procedures in mandibular first molar teeth with symptomatic…
- Trial name
- NCT06820996
- Testing
- Cryotherapy, Control (Standard treatment)
- Where
- Turkey (Türkiye)
- Volunteers
- 132 people
- Sponsor
- Cukurova University
Symptomatic Irreversible Pulpitis
Comparison Between M-Pro and ProTaper Next
Comparing the postoperative pain resulting after mechanical instrumentation using M-pro files versus that resulting after using ProTaper Next rotary files in lower molar with symptomatic Irreversible pulpitis molars.
- Trial name
- NCT03692039
- Testing
- M-pro files in rotating motion, ProTaper Next files in rotating motion
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Postoperative Pain
The Effect of Anti-inflammatory Cryoagent on the Level of Postoperative Pain in Patients With Symptomatic Irreversible Pulpitis and Apical Periodontitis.
The aim of this study is comparative between: 1. Intra-radicular cryotherapy using cold anti-inflammatory {ketorolac tromethamine at 2-5C}. 2.
- Trial name
- NCT06584188
- Testing
- anti-inflammatory ketorolac tromethamine
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Symptomatic Irreversible Pulpitis (SIP)
Effect of Intracanal Cryotherapy Versus Laser Application on Postoperative-pain and Bacterial Load Reduction in Single Visit Root Canal Treatment in Patients With Symptomatic Irreversible Pulpitis in Mandibular First Molar Teeth (Randomized Control Trial)
This randomized controlled clinical trial investigates the Effect of Intracanal Cryotherapy Versus Laser Application on Post-Operative Pain and Bacterial Load Reduction in Single-Visit Root Canal Treatment in Patients with…
- Trial name
- NCT07627867
- Testing
- final irrigation by NaOcl at room temperature, final irrigation by Cryotreated NaOcl, final irrigation by preheated NaOcl
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt
Symptomatic Irreversible Pulpitis, Postoperative Endodontic Pain Following Emergency Root Canal Treatment
Tobradex as Intracanal Medicament
The goal of this prospective clinical study was to evaluate and compare the short-term effects of two intracanal medicaments-calcium hydroxide and a tobramycin-dexamethasone combination (Tobradex)-on postoperative pain following…
- Trial name
- NCT07332936
- Testing
- Calcium Hydroxide (Ca(OH)2), Tobramycin + Dexamethasone
- Where
- Saudi Arabia
- Volunteers
- 43 people
- Sponsor
- Umm Al-Qura University