Clinical trials: Symptoms, Affective
Major Depressive Episode, Suicidal and Self-injurious Behavior
Affective Touch, Hedonia and Suicidal Behavior
Several elements suggest that suicidal vulnerability may be associated with an alteration in the perception of affective touch. On the one hand, anhedonia, characterized by a decrease in the pleasure felt, is strongly associated…
- Trial name
- TOUCH-S (NCT05182827)
- Testing
- Tactile stimulation
- Where
- France
- Volunteers
- 72 people
- Sponsor
- University Hospital, Montpellier
Breast Cancer, Emotional Disturbances
Improving Emotion Regulation at the End of Breast Cancer Treatment
The end of treatment marks the beginning of a challenging period for breast cancer patients. While this period often provokes a sense of relief, it can also be a source of apprehension and vulnerability regarding the future.
- Conditions
- Breast Cancer, Emotional Disturbances, Emotional Dysfunction, Anxiety Depression
- Trial name
- NCT03336827
- Testing
- Cognitive-Behavioral Group Therapy and Hypnosis
- Where
- Belgium
- Volunteers
- 120 people
- Sponsor
- Université Libre de Bruxelles
Major Depressive Disorder, Minor Depressive Disorder
Evaluation of a Stepped Care Approach to Manage Depression in Diabetes
The study examines the efficacy of a stepped care approach for depressed diabetes patients (first study objective). 256 patients with diabetes and comorbid subthreshold or clinical depression will be randomly assigned to either a…
- Conditions
- Major Depressive Disorder, Minor Depressive Disorder, Sub-Threshold Depression, Diabetes Mellitus
- Trial name
- Ecce_homo (NCT01812291)
- Testing
- Step 1: Diabetes-Specific CBT (5 group sessions), Step 2: Depression-Specific CBT (6 single sessions), Step 3: Referral to Psychotherapist and/or Psychiatrist
- Where
- Germany
- Volunteers
- 260 people
- Sponsor
- Forschungsinstitut der Diabetes Akademie Mergentheim
Sleep Deprivation, Sleep
The Effect of Sleep Deprivation and Recovery Sleep on Emotional Memory and Affective Reactivity
To further understand the impact of acute sleep deprivation and recovery sleep on the processing of emotional information the investigators will address and attempt to answer three questions, (i) how both undisturbed sleep and…
- Trial name
- NCT03767426
- Testing
- Sleep Deprivation, Daytime nap
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Asthma, Emotional Disorder
Asthma, Smoking, Emotional Deficits
The objective of the study is to determine whether poor control of asthma is related to an emotional deficit such as alexithymia.
- Conditions
- Asthma, Emotional Disorder, Alexithymia
- Trial name
- ASTADEM (NCT03312673)
- Testing
- Interview and tests of drawing.
- Where
- France
- Volunteers
- 70 people
- Sponsor
- Hospices Civils de Lyon
Organic, Including Symptomatic, Mental Disorders, Substance Use
Exploring the Comorbidity Between Mental Disorders and General Medical Conditions
Mental disorders have been shown to be associated with a number of general medical conditions (also referred to as somatic or physical conditions).
- Conditions
- Organic, Including Symptomatic, Mental Disorders, Substance Use, Schizophrenia, Mood [Affective] Disorders
- Trial name
- COMO-GMC (NCT03847753)
- Testing
- Organic Disorders, Substance Use Disorders, Schizophrenia Disorders
- Volunteers
- 5,940,299 people
- Sponsor
- University of Aarhus
Diabetes Mellitus, Affective Disorders
Depression and Diabetes Control Trial
This randomised controlled trial evaluates a cognitive-behavioural intervention for diabetes patients with suboptimal glycaemic control and comorbid depressive symptoms and/or diabetes distress.
- Conditions
- Diabetes Mellitus, Affective Disorders, Depression, Depressive Symptoms
- Trial name
- DDCT (NCT02675257)
- Testing
- Diabetes-related affective problems analysis, Goal setting towards improvement of glycaemic control, Diabetes-specific problem-solving therapy
- Where
- 2 sites in Germany
- Volunteers
- 213 people
- Sponsor
- Forschungsinstitut der Diabetes Akademie Mergentheim
Major Depressive Disorder
A Personalized Approach to Effects of Affective Bias Modification on Symptom Change and Rumination
This study evaluates the effect of a computerized intervention for depressive symptoms called Affective Bias Modification (ABM).
- Trial name
- NCT04137367
- Testing
- Affective bias modification
- Where
- Norway
- Volunteers
- 108 people
- Sponsor
- University of Oslo
Emotional Disturbance, Emotional Regulation
AI-assisted GNW on Adolescent Emotional Distress
This cluster-randomized controlled trial aims to evaluate the efficacy of an AI-assisted Guided Narrative Writing (AI-GNW) in alleviating emotional distress among adolescents.
- Conditions
- Emotional Disturbance, Emotional Regulation, Insomnia
- Trial name
- NCT07105137
- Testing
- AI-GNW, NF-GNW, NWG
- Where
- China
- Volunteers
- 486 people, healthy volunteers welcome
- Sponsor
- Peking University
Post-stroke Depression
Affective Touching on Poststroke Depression
This mixed-method study includes a randomised controlled trial and an exploratory qualitative study, and aims to examine the effects of caregiver-delivered affective touch on depressive symptoms, state of attachment security…
- Trial name
- NCT03789994
- Testing
- Affective touch, Fine motor exercise
- Where
- China
- Volunteers
- 184 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Mood Disorders, Major Depressive Disorder
Unobtrusive Monitoring of Affective Symptoms and Cognition Using Keyboard Dynamics (UnMASCK)
Mood disorders are associated with significant financial and health costs for the United States, partially due to cognitive problems in these patients that can worsen disease course and impair treatment response.
- Conditions
- Mood Disorders, Major Depressive Disorder, Bipolar Disorder I, Bipolar Disorder II
- Trial name
- UnMASCK (NCT04358900)
- Where
- United States
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Alexithymia, Anxiety
Group Skills Training (DBT vs CBT) for Alexithymia in Young Adult Women
This pilot randomized controlled trial examined whether group skills training based on Dialectical Behavior Therapy (DBT) and Cognitive Behavioral Therapy (CBT) can reduce alexithymia (difficulty identifying and describing…
- Conditions
- Alexithymia, Anxiety, Interpersonal Problems, Emotion Regulation
- Trial name
- NCT07865494
- Testing
- DBT-based Group Skills Training (DBT-GST), CBT-based Group Skills Training (CBT-GST)
- Where
- Turkey (Türkiye)
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Atlas University
Schizophrenia; Psychosis, Schizophrenia and Related Disorders
Accelerated rTMS for Psychomotor Slowing
The goal of this clinical trial is to optimize the treatment of psychomotor slowing in patients with schizophrenia using Transcranial Magnetic Stimulation (TMS).
- Conditions
- Schizophrenia; Psychosis, Schizophrenia and Related Disorders, Schizo Affective Disorder, Brief Psychotic Disorder
- Trial name
- ATMSSlowing (NCT06134661)
- Testing
- cTBS (continuous Theta Burst Stimulation)
- Where
- Switzerland
- Volunteers
- 25 people
- Sponsor
- University of Bern
Schizo-affective Disorder, Non Organic Psychosis
Motivational Intervention for Patients With Schizophrenia
The goal of this clinical trial is to learn if a group therapy called the Positive Emotions Program for Schizophrenia (PEPS) can reduce apathy in adults aged 18 to 60 who have schizophrenia or a related psychotic disorder.
- Conditions
- Schizo-affective Disorder, Non Organic Psychosis, Schizophenia Disorder
- Trial name
- NCT07853079
- Testing
- Positive Emotion Program for Schizophrenia (PEPS), a psychotherapeutic intervention,
- Volunteers
- 88 people
- Sponsor
- University of Geneva, Switzerland
Fibromyalgia
Can Electroencephalography (EEG) Identify the Different Dimensions of Pain in Fibromyalgia?
Studies with quantitative electroencephalogram (qEEG) in people with fibromyalgia showed the existence of distinct patterns of brain electrical activity when compared to healthy individuals.
- Trial name
- NCT05962658
- Testing
- qEEG
- Where
- Brazil
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Pernambuco
Depression
Comparing the Effects of Four Types of Electroconvulsive Therapy on Mood and Thinking in People With Depression
This study will compare four types of electroconvulsive therapy to determine if they differ in their effects on mood, thinking, brain activity, and biochemistry in people with major depressive disorder.
- Trial name
- NCT00487500
- Testing
- Electroconvulsive Therapy (ECT)
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- New York State Psychiatric Institute
Major Depressive Disorder, Bipolar Disorder
Transdiagnostic Markers of Cognitive Symptoms in Disorders Affective.
The objective of this project is to determine the concordance between the subjective and objective evaluation of cognitive functions in affective patients in partial remission through scales and cognitive tests that would be…
- Conditions
- Major Depressive Disorder, Bipolar Disorder, BDMF, GSH
- Trial name
- NCT05523076
- Where
- Spain
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Chronic Pain, Schizophrenia
Assessment and Treatment for Chronic Pain in Veterans With Serious Mental Illness
Chronic pain has a highly negative impact on Veterans, especially those with serious mental illness (SMI). Chronic pain leads to poorer mental health and physical functioning, and represents a critical obstacle to rehabilitation…
- Conditions
- Chronic Pain, Schizophrenia, Psychotic Disorders, Bipolar Disorder
- Trial name
- CPSMI (NCT04118283)
- Testing
- Cognitive Behavioral Therapy for Chronic Pain, Health and Wellness
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- VA Office of Research and Development
Hearing Loss, Hearing Loss, Sensorineural
Does Wearing Hearing Aids Impact the Affective State of Older Adults With Hearing Loss in Their Daily Lives?
The proposed field trial will clarify the real-world effectiveness of HAs in remediating deficits in emotion processing for older adults with mild-to-moderate hearing loss.
- Conditions
- Hearing Loss, Hearing Loss, Sensorineural, Emotions, Stress Physiology
- Trial name
- NCT06249685
- Testing
- Bilateral hearing devices
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- University of Memphis
Major Depressive Disorder, Bipolar Disorder
Naturalistic Study of Ketamine in the Treatment of Depression
This study aims to examine the effect of ketamine in decreasing the risk of suicide in patients with depression and its effectiveness as an antidepressant agent.
- Conditions
- Major Depressive Disorder, Bipolar Disorder, Bipolar Depression, Bipolar I Disorder
- Trial name
- NCT05249309
- Testing
- Ketamine
- Where
- 2 sites in Brazil
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre