Clinical trials: Symptoms, Affective
Burnout, Professional, Occupational Stress
Wellness Tool in Anesthesia Providers
This study will examine the effects of Isha Kriya meditation on stress and burnout among healthcare providers.
- Conditions
- Burnout, Professional, Occupational Stress, Affective Symptoms
- Trial name
- NCT03844308
- Testing
- Isha Kriya Meditation
- Where
- United States
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
PTSD, Depression
Effectiveness of Combined Intervention Approaches in the Treatment of Affective Disorders and Chronic Pain in War Victims
This study will measure the effects of biofeedback supported cognitive behavioral therapy (BF-CBT) and group physiotherapy intervention in victims of torture and massive violence in Kosovo.
- Conditions
- PTSD, Depression, Anxiety, Chronic Pain
- Trial name
- NCT01696578
- Testing
- BF-CBT and group physiotherapy
- Where
- Kosovo
- Volunteers
- 31 people
- Sponsor
- Rehabilitation and Research Centre for Torture Victims
Stress, Anxiety
The Wild Man Programme - a Nature-based Rehabilitation Enhancing Quality of Life for Men on Long-term Sick Leave
The aim of the present study is to examine whether the nature based 'Wild man Programme' can help to increase quality of life among men on sick leave compared to treatment as usual.
- Conditions
- Stress, Anxiety, Depression, Cardiac Disease
- Trial name
- NCT04073524
- Testing
- Nature-Body-Mind-Community, Treatment as usual
- Where
- Denmark
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Bipolar Disorder, Affective Disorders, Psychotic
A Study to Evaluate the Safety and Effectiveness of Topiramate Compared to Placebo in the Treatment of Patients With Bipolar I Disorder
The purpose of this study is to determine the safety and efficacy of topiramate in adolescents with manic or mixed episodes of Bipolar I Disorder.
- Conditions
- Bipolar Disorder, Affective Disorders, Psychotic, Mood Disorders, Mental Disorders
- Trial name
- NCT00035802
- Testing
- Topiramate
- Volunteers
- 13 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Bipolar Depression
Ceftriaxone in the Management of Bipolar Depression
We aim to study the efficacy of intravenous ceftriaxone in a four-week, inpatient, placebo-controlled, double-blind study, as an augmentation therapy in patients with bipolar disorder, currently depressed, who have failed to…
- Trial name
- NCT00566111
- Testing
- ceftriaxone, Saline solution
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Yale University
Emotional Disturbance, Behavior Disorders in Children
Family Connections
The Family Connections study, is intended to disrupt disparities in mental health treatment access for children at-risk for childhood trauma (ACEs) and/or serious emotional disturbance (SED).
- Trial name
- NCT06662357
- Testing
- Behavioral Treatment
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Cambridge Health Alliance
Bipolar Disorder, Schizophrenia
Tachyphylaxis, Tolerance, & Withdrawal Post Treatment With Igalmi for Agitation in Schizophrenia or Bipolar Disorder
This is an in-clinic, single arm, open-label study assessing tachyphylaxis, tolerance, and withdrawal following repeated doses of Igalmi in adult males and females with agitation associated with schizophrenia or bipolar disorder.
- Conditions
- Bipolar Disorder, Schizophrenia, Agitation,Psychomotor, Schizo Affective Disorder
- Trial name
- NCT06041646
- Testing
- Sublingual film containing Igalmi
- Where
- 2 sites in United States
- Volunteers
- 29 people
- Sponsor
- BioXcel Therapeutics Inc
Mental Disorders
The Genetic and Affective Prediction Study
A major proportion of patients admitted to psychiatric acute and emergency departments have symptoms, behaviors or function influenced by implicit or explicit suicidal intention (tendency towards self-harm, or suicide attempt).
- Trial name
- GAP (NCT02625818)
- Where
- Norway
- Volunteers
- 400 people
- Sponsor
- St. Olavs Hospital
Depression, Physical Inactivity
Physical Exercise as Adjunctive Therapy for Affective Disorder and Anxiety
"Braining" is a clinical method for physical exercise as adjunctive therapy in psychiatric care. The core components are personnel-led group training sessions and motivating contact with psychiatric staff, as well as measurement…
- Conditions
- Depression, Physical Inactivity, Bipolar Disorder, Anxiety Disorders
- Trial name
- NCT05157386
- Testing
- Braining
- Where
- Sweden
- Volunteers
- 50 people
- Sponsor
- Region Stockholm
Major Depressive Disorder
Treatment Outcome in Major Depressive Disorder
Major Depressive Disorder (MDD) is one of the most severe and frequently occurring brain disorders worldwide. It has been linked to serotonergic dysfunction, sexual dysfunction, vulnerability to stress and neuro-inflammation.
- Trial name
- NCT02869035
- Testing
- Escitalopram, Duloxetine
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Schizophrenia, Schizoaffective Disorder
A Clinical Trial to Examine Effects of Atomoxetine in the Treatment of Negative Symptoms in Patients With Schizophrenia
This study proposes to examine the effect of atomoxetine on quality of life and negative symptoms such as social withdrawal, lack of interest in things, lack of thought content, flat emotions, slowed body movements and lack of…
- Trial name
- NCT00222794
- Testing
- Atomoxetine (Strattera)
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- University of Pittsburgh
Affective Psychosis, Bipolar, Manic Disorder
Phase 3 /Seroquel SR Acute Mania Monotherapy - US
The purpose of this study is to determine the safety and efficacy of sustained-release quetiapine fumarate (Seroquel®) in the treatment of patients with Acute Bipolar Mania for 3 weeks.
- Conditions
- Affective Psychosis, Bipolar, Manic Disorder, Manic-Depressive Psychosis, Mania
- Trial name
- NCT00422123
- Testing
- Quetiapine fumarate (Seroquel) SR
- Where
- 51 sites in United States
- Volunteers
- 447 people
- Sponsor
- AstraZeneca
Mild Traumatic Brain Injury, Alexithymia
Clinical Trial Comparing the Efficacy of Two Teletherapy Programs at Improving Psychological Health in People With Brain Injury
The purpose of the study is to test two different training programs to find out which is better at helping people with a concussion or mild TBI (mTBI) improve their emotional health and well-being.
- Trial name
- NCT07436754
- Testing
- Program 1, Program 2
- Where
- 3 sites in United States
- Volunteers
- 300 people
- Sponsor
- Hackensack Meridian Health
Mood Disorders, Sleep Disorders
Family Study of Affective and Anxiety Spectrum Disorders
This study will examine how depression, anxiety, and migraine run in families. It will help in defining the risk factors for physical, mental, and health problems-as well as define ways that those problems may be prevented and…
- Conditions
- Mood Disorders, Sleep Disorders, Migraine
- Trial name
- NCT00071786
- Where
- United States
- Volunteers
- 1,944 people
- Sponsor
- National Institute of Mental Health (NIMH)
Behavioral Symptoms, Emotional Disturbances
Transdiagnostic Group Intervention for Children With Behavior Problems
This study fills a notable gap in the transdiagnostic literature by evaluating whether an evidence-based transdiagnostic treatment for emotional disorders such as the Unified Protocol for Children (UP-C) is effective for treating…
- Trial name
- NCT02794051
- Testing
- Group Therapy
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of Colorado, Denver
Affective Spectrum Symptoms
Gene-environment Interactions in Families With Adolescents (Gen-omgevingsinteracties in Gezinnen Met Adolescenten)
English: The main purpose of this study is to investigate the developmental trajectories of parents and adolescents in the Flemish region of Belgium.
- Trial name
- GiGA (NCT05716412)
- Where
- 2 sites in Belgium
- Volunteers
- 1,326 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Acute Pain, Chronic Pain, Widespread
Ketamine's Effect Changes the Cortical Electrophysiological Activity Related to Semantic Affective Dimension of Pain
This is a clinical trial that intend to determine the effects of S-ketamine on event-related potentials associated with semantic affective pain-processing
- Conditions
- Acute Pain, Chronic Pain, Widespread, Schizophrenia
- Trial name
- NCT03915938
- Testing
- Ketamine
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre
Obesity, Craving
Efficacy of a Cognitive - Affective - Addictive Based Intervention to Decrease Food Craving in Obese Patients.
Since the 80's, the prevalence of obesity has more than doubled and despite progression of knowledge, interventions usually lead to a transient reduction in body weight that is not maintained in the long-term.
- Conditions
- Obesity, Craving, Cognitive Behavioral Therapy, Cognitive Remediation Therapy
- Trial name
- OBESADEM (NCT04338178)
- Testing
- Cognitive Remediation Therapy (CRT), Emotional Skills Training (EST), Cognitive Behavioral Therapy
- Where
- 3 sites in France
- Volunteers
- 144 people
- Sponsor
- University Hospital, Bordeaux
Interoceptive Awareness, Interoception
Haptic Feedback for Improved Interoceptive Awareness and Mental Well-being
This study investigates the relationship between heart-beat haptic feedback on interoceptive awareness and mental-wellbeing. Previous research showed non-significant results in short-term emotion regulation tasks when given…
- Conditions
- Interoceptive Awareness, Interoception, Alexithymia, Anxiety
- Trial name
- NCT07809958
- Testing
- Heart rate feedback from smartwatch
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Massachusetts Institute of Technology
Affective Symptoms
Effect of the Involvement of a Medical Clown on the Labor Experience
The experience of labor for a woman can be rewarding but can be traumatic. Medical clowning may alleviate the potential for trauma.
- Trial name
- LaborClown (NCT03171896)
- Testing
- clown
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- The Baruch Padeh Medical Center, Poriya