Clinical trials: Symptoms, Affective
Major Depression, Bipolar Affective Disorder
Treatment Response In ECT Patients
Clarification Regarding Study Type: Observational This study is a prospective, non-interventional observational study. The decision to administer Electroconvulsive Therapy (ECT) and the selection of the anesthetic agent (ketamine…
- Conditions
- Major Depression, Bipolar Affective Disorder, Bipolar Depression Depressed Phase
- Trial name
- NCT07463911
- Testing
- Electroconvulsive Therapy (ECT)
- Where
- Turkey (Türkiye)
- Volunteers
- 65 people
- Sponsor
- Nurdan Sağbaş
Chronic Pain, Musculoskeletal Pain
Lessons in Affect Regulation to Keep Stress and Pain UndeR Control (LARKSPUR R34)
Chronic pain affects millions of Americans but integrative as well as conventional treatments fall short in terms of alleviating this pain.
- Trial name
- LARKSPUR (NCT03699553)
- Testing
- LARKSPUR; Online Positive Emotions Skills for Individuals with Chronic Musculoskeletal Pain, Emotion Reporting Control Group
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Northwestern University
Alexithymia, Empathy Skills
Film-Based Medical Education and Social Justice Course: Effects on Alexithymia and Empathy in Medical Students
This study will examine whether a 14-week elective course that uses films and guided discussion on social justice in health care can improve medical students' empathy skills and reduce alexithymia (difficulty recognizing and…
- Conditions
- Alexithymia, Empathy Skills, Education, Medical, Social Justice Advocacy
- Trial name
- NCT07399366
- Testing
- Film-Based Medical Education and Social Justice Elective
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Çanakkale Onsekiz Mart University
Emotional Disturbances
Systematic Efficacy Replication Study of Conjoint Behavioral Consultation in Elementary Schools
The purpose of this project is to conduct an impact evaluation of the Conjoint Behavioral Consulting (CBC) intervention under real-world conditions as an IES Efficacy Replication trial.
- Trial name
- NCT05466214
- Testing
- Conjoint Behavioral Consultation (CBC)
- Where
- United States
- Volunteers
- 720 people, healthy volunteers welcome
- Sponsor
- American Institutes for Research
COPD, Dyspnea
Pulmonary Rehabilitation, Dyspnoea and Emotional Cognition in COPD
To evaluate whether pulmonary rehabilitation improves emotional cognition, using facial emotions recognition and smile production, by improving the emotional dimension of dyspnoea in patients with chronic obstructive pulmonary…
- Conditions
- COPD, Dyspnea, Rehabilitation; Tobacco Use, Emotional Disturbances
- Trial name
- READ-COG BPCO (NCT03092700)
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Association pour le Développement et l'Organisation de la Recherche en Pneumologie et sur le Sommeil
Bipolar Affective Disorder, Depression
Mitochondrial Dysfunction in the Pathophysiology and Treatment of Bipolar Disorder
This study will examine whether mitochondrial function is impaired in patients with bipolar disorder. Mitrochondria are small organelles inside the cell that are responsible for energy production.
- Trial name
- NCT00327756
- Testing
- Coenzyme Q10
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Premenstrual Dysphoric Disorder
Premenstrual Hormonal and Affective State Evaluation (PHASE) Project
PHASE is designed to evaluate neuroactive hormone trajectories across the menstrual cycle and endocrine, autonomic, and subjective responses to psychosocial stress in women suffering from severe PMS (i.e., premenstrual dysphoric…
- Trial name
- PHASE Project (NCT03862469)
- Testing
- Individualized laboratory test
- Where
- United States
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Sexual Behavior, Sexually Transmitted Disease (STD)
Cultural Adaptation, Validation, and Evaluation of the Programme for Promotion of Healthy Affective-Sexual Behaviours in Adolescents (IYG)
The investigators are writing to inform participants about a study being carried out by a research group from the University of Granada and the University of Seville, in which the participant's son/daughter is invited to…
- Conditions
- Sexual Behavior, Sexually Transmitted Disease (STD), Condom Use, Adolescent Health
- Trial name
- IYG (NCT07208045)
- Testing
- Es tu juego: decide bien (IYG)
- Where
- Spain
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- University of Seville
Schizophrenia, Schizoaffective Disorder
A Clinical Trial to Examine Effects of Atomoxetine in the Treatment of Negative Symptoms in Patients With Schizophrenia
This study proposes to examine the effect of atomoxetine on quality of life and negative symptoms such as social withdrawal, lack of interest in things, lack of thought content, flat emotions, slowed body movements and lack of…
- Trial name
- NCT00222794
- Testing
- Atomoxetine (Strattera)
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- University of Pittsburgh
Behavior Problem, Development Delay
Family Nurture Intervention, A Group Model in Connecticut
The purpose of this current study is to investigate the efficacy of a group model of Family Nurture Intervention in ameliorating behavioral problems in preschool-aged children.
- Conditions
- Behavior Problem, Development Delay, Emotional Disturbance, Family Conflict
- Trial name
- NCT02970565
- Testing
- Family Nurture Intervention, Nutrition and Play Intervention
- Where
- United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Columbia University
Bipolar Disorder, Affective Disorders, Psychotic
A Study to Evaluate the Safety and Effectiveness of Topiramate Compared to Placebo in the Treatment of Patients With Bipolar I Disorder
The purpose of this study is to determine the safety and efficacy of topiramate in adolescents with manic or mixed episodes of Bipolar I Disorder.
- Conditions
- Bipolar Disorder, Affective Disorders, Psychotic, Mood Disorders, Mental Disorders
- Trial name
- NCT00035802
- Testing
- Topiramate
- Volunteers
- 13 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Cerebellar Diseases
Emotional Communication Disorders in Cerebellar Disease
The cerebellum has been linked to cognitive and emotional functions and there is increasing evidence that damage to posterior portions of the cerebellum can result in frontal-executive, visuospatial, and verbal deficits…
- Trial name
- NCT02106819
- Testing
- Testing of emotional communication ability, magnetic resonance imaging (MRI) of the brain
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- University of Florida
Depression - Major Depressive Disorder, Anxiety
No Time to Wait: Single Session Intervention
Mental health problems in youth are prevalent, but early intervention effectively reduces symptoms, substance abuse risk, suicide, and comorbidities.
- Trial name
- NCT07383467
- Testing
- Online Single Session Intervention on Growth Mindset
- Where
- Hong Kong
- Volunteers
- 124 people
- Sponsor
- United Christian Hospital
Perimenopausal Disorder, Stress, Emotional
The Menopause Transition: Estrogen Variability, Stress Reactivity and Mood
Women in the menopause transition ('perimenopause') are exposed to extreme hormone variability, tend to experience a unique set of severe stressors (e.g., divorce, death of loved ones), and are also at substantially elevated risk…
- Trial name
- Changes (NCT03003949)
- Testing
- Estradiol Patch, 0.1 Mg/24 Hours Weekly Transdermal Film, Extended Release, Progesterone Capsule
- Where
- 2 sites in United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Depressive Disorder, Major, Persistent Depressive Disorder
Effectiveness of an Ecological Momentary Emotion Regulation Intervention
This two-armed randomized controlled trial aims to investigate the effectiveness of an emotion regulation intervention in individuals with and without depressive disorders.
- Conditions
- Depressive Disorder, Major, Persistent Depressive Disorder, Healthy
- Trial name
- NCT06311136
- Testing
- Valence-Specific Ecological Momentary Intervention
- Where
- Germany
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Heidelberg University
Schizophrenia, Affective Symptoms
Atypical Antipsychotics in the Treatment of Affective Symptoms of Schizophrenia in Hungary
This is a noninterventional observational study lead amongst psychiatrists, to assess the the overall status of schizophrenic outpatients with affective symptoms treated with atypical antipsychotics.
- Trial name
- AFFECT (NCT01534936)
- Where
- 53 sites in Hungary
- Volunteers
- 2,153 people
- Sponsor
- AstraZeneca
Healthy, Psychological Well Being
Survey of Psychological Well-being of Health Care Workers in the Hospital Setting
The psychological well-being of healthcare workers in hospital settings is a topic of growing interest in the scientific literature, given the crucial importance of their role in ensuring high-quality care.
- Conditions
- Healthy, Psychological Well Being, Stress Response, Professional Quality of Life
- Trial name
- IN-VISIBLE (NCT06923436)
- Testing
- Psychological Assessment
- Volunteers
- 500 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Diabetes Mellitus, Affective Disorders
Depression and Diabetes Control Trial
This randomised controlled trial evaluates a cognitive-behavioural intervention for diabetes patients with suboptimal glycaemic control and comorbid depressive symptoms and/or diabetes distress.
- Conditions
- Diabetes Mellitus, Affective Disorders, Depression, Depressive Symptoms
- Trial name
- DDCT (NCT02675257)
- Testing
- Diabetes-related affective problems analysis, Goal setting towards improvement of glycaemic control, Diabetes-specific problem-solving therapy
- Where
- 2 sites in Germany
- Volunteers
- 213 people
- Sponsor
- Forschungsinstitut der Diabetes Akademie Mergentheim
Bipolar I Disorder, Bipolar II Disorder
Individualized Pharmacological Approach to Obesity in Patients With Bipolar Disorder
The goal of this clinical trial is to identify the specific characteristics (phenotypes) that may be useful to help select the right medication for weight loss, and to study the effect of individualized guided medication in…
- Conditions
- Bipolar I Disorder, Bipolar II Disorder, Schizo Affective Disorder, Obesity
- Trial name
- OBOE-Mayo (NCT07213466)
- Testing
- Group Therapy Program, semaglutide, Phentermine-Topiramate
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Mayo Clinic
Alzheimer Disease
Advancing Alzheimer's Care: Home-based tDCS for Affective Symptoms
Participants will be asked to participate in this research study of a device that creates transcranial direct current stimulation (tDCS).
- Trial name
- NCT06801639
- Testing
- Transcranial direct current stimulation (tDCS)
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- The University of Texas Health Science Center at San Antonio