Clinical trials: Symptoms, Affective
Alexithymia, HIV
Role of CBD in Improving Alexithymia
Given the treatments that are available today for HIV disease, people living with HIV (PLWH) can generally expect good medical outcomes.
- Trial name
- ACBD (NCT05832281)
- Testing
- Purysis CBD
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- University of California, San Diego
Bereavement
Long-term Consequences of Bereavement in Children, Adolescents and Young Adults
The purpose of this study is to examine how the death of a parent as a child, adolescent or young adult affects health and psychosocial wellbeing in adult life and to evaluate the impact in adult life of counseling to children…
- Trial name
- NCT01453699
- Where
- Denmark
- Volunteers
- 1,225,660 people, healthy volunteers welcome
- Sponsor
- Danish Cancer Society
Depression, Bipolar Affective Disorder
The Efficacy of a Transdiagnostic Sleep and Circadian Intervention for Patients With Mental Disorders and Sleep Problems
The aim of this study is to examine the effect of a non-pharmacological transdiagnostic sleep intervention as add on to standard treatment for bipolar disorder, depression and attention deficit disorder.
- Conditions
- Depression, Bipolar Affective Disorder, Attention Deficit Disorder
- Trial name
- NCT05406414
- Testing
- Transdiagnostic sleep and circadian treatment, Active waitlist control group
- Where
- Denmark
- Volunteers
- 88 people
- Sponsor
- University of Aarhus
Seasonal Affective Disorder, Depression
Cognitive Behavioral Therapy for the Treatment of Seasonal Affective Disorder (SAD)
This study will assess the effectiveness of cognitive behavioral therapy (CBT) in treating seasonal affective disorder (SAD), commonly called the "winter blues."
- Trial name
- NCT00076245
- Testing
- Light Therapy, Cognitive behavioral therapy (CBT)
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- Henry M. Jackson Foundation for the Advancement of Military Medicine
Schizophrenia Relapse, Schizophrenia
Feasibility and Acceptability of a Smartphone App to Assess Early Warning Signs of Psychosis Relapse
About 1 in 100 people will experience an episode of psychosis. Some people will only experience one 'psychotic episode' and about a quarter of people make a full recovery.
- Conditions
- Schizophrenia Relapse, Schizophrenia, Schizo Affective Disorder, Psychotic Disorders
- Trial name
- ExPRESS:2 (NCT03558529)
- Volunteers
- 27 people
- Sponsor
- Manchester Academic Health Science Centre
Eating Disorders
Strength Training and Eating Disorders
The aim of this pilot study is to test feasibility of assessment methods and immediate responses to two different strength training sessions, maximal strength training and hypertrophy strength training, among persons undergoing…
- Trial name
- NCT06809244
- Testing
- Exercise
- Where
- 2 sites in Norway
- Volunteers
- 30 people
- Sponsor
- University of South-Eastern Norway
Inflammatory Bowel Diseases, Mild Cognitive Impairment
Cognitive Impairment and Affective Mood Disorders in Patients With IBD
The aim is to evaluate the presence of mild cognitive impairment (MCI) in patients with inflammatory bowel disease (IBD). This will be done by cognitive tests.
- Conditions
- Inflammatory Bowel Diseases, Mild Cognitive Impairment, Depression, Anxiety
- Trial name
- COGN-IBD-1 (NCT05760729)
- Testing
- Cognitive testing
- Where
- 3 sites in Romania
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Iuliu Hatieganu University of Medicine and Pharmacy
Schizophrenia, Bipolar Affective Disorder
A Study on the Preference of Risperidone Dosage Forms
This study aimed to understand patients' needs and preferences for antipsychotic dosage forms.
- Conditions
- Schizophrenia, Bipolar Affective Disorder, Autism Spectrum Disorder, Conduct Disorder
- Trial name
- NCT06657430
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Shanghai Mental Health Center
Depression
CALM Phase 2b Pilot
Managing Cancer And Living Meaningfully (CALM) is a brief psychotherapy designed to alleviate distress in advanced cancer. In an earlier intervention-only pilot trial, CALM was associated with reductions in depressive symptoms…
- Trial name
- CALM (NCT02353546)
- Testing
- CALM
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- University Health Network, Toronto
Depression in Remission, Depressive Symptoms
Mood and Thought Process Study
The primary objective for this project is to test whether affective executive functioning is a mechanism of action of mindfulness-based cognitive therapy and Wellness for Wellbeing. The main questions it aims to answer are: 1.
- Conditions
- Depression in Remission, Depressive Symptoms, Depression
- Trial name
- MAT Process (NCT05585775)
- Testing
- Mindfulness-Based Cognitive Therapy, Wellness for Wellbeing
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Butler Hospital
Psoriasis, Neuroinflammation
Neuroinflammation, Affective and Cognitive Symptoms in Major Depression and Psoriasis
Objectives: To identify peripheral neuroinflammatory markers in patients suffering from major depression or psoriasis in relation to affective symptoms (anxiety, depression, irritability), fatigue and cognitive symptoms; and…
- Conditions
- Psoriasis, Neuroinflammation, Major Depressive Disorder, Cognitive Symptom
- Trial name
- INPSYDER (NCT04423471)
- Testing
- Sociodemographic variables
- Where
- Spain
- Sponsor
- Germans Trias i Pujol Hospital
Major Depressive Disorder
Dose-finding Study With Lu AA24530 in Major Depressive Disorder
The primary purpose of this study is to assess the efficacy in treating patients with Major Depressive Disorder of one or more doses of Lu AA24530 relative to placebo
- Trial name
- NCT00599911
- Testing
- Lu AA24530, Duloxetine
- Where
- 72 sites in Australia, Austria and 15 more
- Volunteers
- 652 people
- Sponsor
- H. Lundbeck A/S
Alcohol Use Disorder (AUD), Alcohol-Related Disorders
Body-Focused Mindfulness as an Add-on Intervention in Inpatient Alcohol Use Disorder Treatment (MBI-AUD-PL)
The goal of this clinical trial is to learn if a body-focused mindfulness program can help people with alcohol use disorder (AUD) feel more connected to their bodies and manage their emotions better.
- Trial name
- MBI-AUD-PL (NCT07706660)
- Testing
- Body-Focused Mindfulness Intervention, Standard Psychoeducation
- Where
- Poland
- Volunteers
- 240 people
- Sponsor
- Medical University of Warsaw
Bipolar Disorder, Manic, Artificial Intelligence
Correlation of Audiovisual Features With Clinical Variables and Neurocognitive Functions in Bipolar Disorder, Mania
The aim of this study is to show the physiological changes during manic episode in bipolar mania how much they differentiate from remission and healthy control.
- Conditions
- Bipolar Disorder, Manic, Artificial Intelligence, Neurocognition, Treatment Resistant Disorders
- Trial name
- NCT03857438
- Testing
- Ongoing treatment for bipolar mania, Audiovisual recording during guided presentation
- Where
- Turkey (Türkiye)
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Istanbul Saglik Bilimleri University
Relation, Mother-Child, Family Conflict
Children's Learning Centers Group FNI
The purpose of this study is to compare the effects of Family Nurture Intervention in a mother-child group setting with a Standard Children's Learning Center (CLC) Program for preschool-aged children (ages 2-4.5).
- Conditions
- Relation, Mother-Child, Family Conflict, Emotional Disturbances, Behavior Problem
- Trial name
- NCT03908268
- Testing
- Family Nurture Intervention (FNI), Standard Children's Learning Center (CLC) Program
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Columbia University
Psychotic Disorders, Affective Disorder
Physical Activity, Psychopathology, and Quality of Life in People With Psychotic or Affective Disorders
This longitudinal observational study tests the associations between physical activity, health-related quality of life, and psychopathology symptoms among people diagnosed with schizophrenia or diagnosed with affective disorders.
- Trial name
- NCT05869409
- Testing
- Physical activity and sedentary behavior education
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- University of Social Sciences and Humanities, Warsaw
Brain Damage, Chronic, Cerebellar Cognitive Affective Syndrome
DTI & Tractography in Pediatric Tumor Surgery
The goal of this project will be to demonstrate that Synaptive Medical's Diffusion Tensor Imaging(DTI) product functionality used in pre-operative planning and intraoperative surgical navigation, improves clinical outcomes…
- Conditions
- Brain Damage, Chronic, Cerebellar Cognitive Affective Syndrome, Cerebellar Mutism
- Trial name
- NCT02810626
- Testing
- BrightMatter™ products
- Volunteers
- 24 people
- Sponsor
- London Health Sciences Centre
Bipolar Depression
Levetiracetam in the Management of Bipolar Depression
A 6-week outpatient, double-blind, placebo-controlled, add-on trial to investigate the effects of levetiracetam on depressive symptoms in bipolar depressed patients.
- Trial name
- NCT00566150
- Testing
- Levetiracetam
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Yale University
Fronto-temporal Dementia, Fronto-temporal Lobar Dementia
Vortioxetine for the Treatment of Mood and Cognitive Symptoms in Frontotemporal Dementia
The goal of this clinical trial is to learn if vortioxetine improves mood symptoms and cognition in patients with early-stage behavioral variant Frontotemporal Dementia (bvFTD).
- Conditions
- Fronto-temporal Dementia, Fronto-temporal Lobar Dementia, Frontotemporal Degeneration, Frontotemporal Dementia (FTD)
- Trial name
- NCT06604520
- Testing
- Vortioxetine
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Seasonal Affective Disorder, Visual Impairment
Seasonal Affective Disorder and Visual Impairment
As a subtype of major depressive disorder, seasonal affective disorder (SAD) or winter depression causes severe reductions in both quality of life and productivity and results in high morbidity and frequent sick leave (1).
- Trial name
- NCT03403959
- Testing
- light therapy
- Where
- Denmark
- Volunteers
- 18 people
- Sponsor
- Psychiatric Centre Rigshospitalet