Clinical trials: Symptoms, Affective
Physical Inactivity, Overweight or Obesity
eMOTION: Examining Affective Mechanisms in Physical Activity Engagement
This early-phase trial will test intervention strategies to influence affective mechanisms underlying physical activity and determine whether changes in those mechanisms result in change in physical activity behavior among…
- Conditions
- Physical Inactivity, Overweight or Obesity, Cancer
- Trial name
- NCT06570642
- Testing
- Physical Activity Goals mHealth Intervention, TYPE/CONTEXT enhancement, SAVOR enhancement
- Where
- United States
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Chronic Pain, Schizophrenia
Assessment and Treatment for Chronic Pain in Veterans With Serious Mental Illness
Chronic pain has a highly negative impact on Veterans, especially those with serious mental illness (SMI). Chronic pain leads to poorer mental health and physical functioning, and represents a critical obstacle to rehabilitation…
- Conditions
- Chronic Pain, Schizophrenia, Psychotic Disorders, Bipolar Disorder
- Trial name
- CPSMI (NCT04118283)
- Testing
- Cognitive Behavioral Therapy for Chronic Pain, Health and Wellness
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- VA Office of Research and Development
Anorexia Nervosa
The Experience of Affective Touch in Anorexia Nervosa
The aim of the present research will be to verify if the pleasantness of affective touch is comparable between women with AN and healthy women while measuring the level of social anhedonia and the lifespan experience of affective…
- Trial name
- AffTouch_AN (NCT05756530)
- Testing
- Affective touch paradigm
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Istituto Auxologico Italiano
Impulsivity, Bipolar Disorder
CBT for Problematic Impulsive Behaviours in Bipolar Disorder: A Case Series / CBT-PIB
The goal of this case series is to explore whether a talking therapy, specifically Cognitive Behavioural Therapy (CBT) is acceptable and feasible in the management of mood-driven impulsive behaviours in people with bipolar…
- Conditions
- Impulsivity, Bipolar Disorder, Hypomania, Bipolar I Disorder
- Trial name
- NCT06129500
- Testing
- Cognitive Behavioural Therapy for Problematic Impulsive Behaviours
- Where
- United Kingdom
- Volunteers
- 10 people
- Sponsor
- University of Exeter
Fibromyalgia
Healing Through Affective Self-Awareness in Fibromyalgia: a Randomized Controlled Trial
The investigators are studying whether a brief three-session mind-body workshop helps people with fibromyalgia. The investigators hypothesize that this workshop will significantly improve pain and other symptoms, compared to…
- Trial name
- NCT00437411
- Testing
- Affective Self-Awareness workshop
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- Mike Hsu
Depression, Premenstrual Dysphoric Disorder (PMDD)
Neurofeedback Treatment of Affective Instability in Premenstrual Dysphoric Disorder(PMDD)
Premenstrual Dysphoric Disorder (PMDD) is characterized by affective instability and irritability, diagnosed in 5% of reproductive-age women.
- Trial name
- NCT01945372
- Testing
- EEG NeuroFeedback
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Pain, Anxiety
Multimedia Information for Patients With Renal Biopsy
This study takes place in the Divisions of Nephrology. Patients undergoing renal biopsy were randomized to control group or multimedia information intervention group.
- Conditions
- Pain, Anxiety, Hematuria
- Trial name
- NCT04971057
- Testing
- multimedia information program of renal biopsy
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- National Taipei University of Nursing and Health Sciences
Temperament, Sleep
GUTLINK4KIDS Intervention
This study aims to investigate the chronic effects of prebiotic consumption on cognitive, behavioural and gut microbiome outcomes in children aged 3-5 years.
- Conditions
- Temperament, Sleep, Cognition, Emotion Regulation
- Trial name
- GUTLINK4KIDS (NCT07401212)
- Testing
- Prebiotic powder
- Where
- United Kingdom
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- University of Reading
Bipolar Affective Disorder, Major Depressive Disorder
Exosome for Early Diagnosis of Bipolar Affective Disorder
Objectives: Bipolar disorder (BD) is a chronic and recurrent mental illness characterized by depressive episodes and manic or hypomanic episodes, leading to severe functional impairment and cognitive damage.
- Trial name
- NCT05915312
- Where
- China
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Tianjin Anding Hospital
Bipolar Disorder, Bipolar Affective Psychosis
Effectiveness of Quetiapine XR on the Control of Symptoms of Manic Phase of Bipolar Disorder.
The primary purpose of the study is to assess the efficacy of Quetiapine extended release 600mg per day either as monotherapy or combined therapy in the treatment of patients with mania associated to Bipolar disorder.
- Conditions
- Bipolar Disorder, Bipolar Affective Psychosis, Mania, Manic Disorder
- Trial name
- EMMY (NCT00521365)
- Testing
- Quetiapine 600mg
- Where
- 7 sites in Mexico
- Volunteers
- 88 people
- Sponsor
- AstraZeneca
Major Depressive Disorder
A Personalized Approach to Effects of Affective Bias Modification on Symptom Change and Rumination
This study evaluates the effect of a computerized intervention for depressive symptoms called Affective Bias Modification (ABM).
- Trial name
- NCT04137367
- Testing
- Affective bias modification
- Where
- Norway
- Volunteers
- 108 people
- Sponsor
- University of Oslo
Depression, Inflammation
Precision Psychiatry for Depression: Immune Response and Affective Symptoms as Predictors of Response to Antidepressants
Objectives: To identify in patients with major depression different peripheral markers of neuroinflammation in relation to affective symptoms (anxiety, depression, irritability), fatigue and cognitive symptoms; and its…
- Conditions
- Depression, Inflammation, Antidepressants, Immunity
- Trial name
- LYMPHODEP (NCT06337539)
- Testing
- SSRI
- Where
- Spain
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Germans Trias i Pujol Hospital
Burnout, Emotional Disturbances
Mindfulness-based Therapy Versus Relaxation in Prevention of Burnout in Medical Students
A recent survey exploring mental health in a large cohort of French medical students and young graduates (N = 21.768), observed that 68.2% of participants showed pathologic anxiety.
- Conditions
- Burnout, Emotional Disturbances, Depression
- Trial name
- MUSTPrevent (NCT04026594)
- Testing
- Mindfulness Based Stress Reduction, Relaxation group
- Where
- France
- Volunteers
- 612 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Traumatic Brain Injury, Alexithymia
The Emotion Builder: An Intervention for Emotional Deficits After Brain Injury
The purpose of this study is to examine a web-based training program for treating emotional problems in people who have suffered a traumatic brain injury (TBI).
- Trial name
- NCT02432300
- Testing
- Emotion Builder
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- EmotEd
Attention Deficit Disorder With Hyperactivity, Bipolar Disorder
Genetic Aspects of Neurologic and Psychiatric Disorders
The purpose of this study is to improve the understanding of the genetic causes of specific neurologic and psychiatric disorders.
- Conditions
- Attention Deficit Disorder With Hyperactivity, Bipolar Disorder, Mental Disorder Diagnosed in Childhood, Mental Retardation
- Trial name
- NCT00001544
- Where
- United States
- Volunteers
- 1,227 people
- Sponsor
- National Institute of Mental Health (NIMH)
Major Depressive Disorder
Treatment Outcome in Major Depressive Disorder
Major Depressive Disorder (MDD) is one of the most severe and frequently occurring brain disorders worldwide. It has been linked to serotonergic dysfunction, sexual dysfunction, vulnerability to stress and neuro-inflammation.
- Trial name
- NCT02869035
- Testing
- Escitalopram, Duloxetine
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Behavioral and Psychiatric Symptoms of Dementia
rTMS for the Treatment of Affective Symptoms in Patients Suffering From Dementia
This is a monocentric prospective, randomized, double-blind placebo-controlled study. It is designed to evaluate the superiority of the rTMS over sham treatment of depressive symptoms in the context of dementia.
- Trial name
- rTMS-PSYGER (NCT05262868)
- Testing
- rTMS
- Where
- Switzerland
- Volunteers
- 44 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Depression
Using Affective Differences to Predict Response to Behavioral Treatment for Major Depressive Disorder
This study will determine how people with depression differ from healthy people in brain activity and interpreting emotions, both before and after receiving a psychotherapy treatment.
- Trial name
- NCT00909220
- Testing
- Behavioral Activation
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Neurocognitive Disorders, Cognitive Dysfunction
A Pilot Randomized Controlled Trial: CoINTEGRATE
The purpose of this study is to examine the feasibility of comprehensive multimodal individually tailored Cognitive Behavioral Therapy (CBT), Cognitive Rehabilitation Therapy (CRT), and modifiable lifestyle sessions.
- Conditions
- Neurocognitive Disorders, Cognitive Dysfunction, Traumatic Brain Injury, Multiple Sclerosis
- Trial name
- CoINTEGRATE (NCT05732285)
- Testing
- CRT, CBT, Modifiable lifestyle factors
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Michigan
Acute Pain, Chronic Pain, Widespread
Ketamine's Effect Changes the Cortical Electrophysiological Activity Related to Semantic Affective Dimension of Pain
This is a clinical trial that intend to determine the effects of S-ketamine on event-related potentials associated with semantic affective pain-processing
- Conditions
- Acute Pain, Chronic Pain, Widespread, Schizophrenia
- Trial name
- NCT03915938
- Testing
- Ketamine
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre