Clinical trials: Symptoms, Affective
Multiple Sclerosis, Emotional Disturbances
A Social Emotion Regulation Intervention in MS
The current project will examine effectiveness of an intervention based on the concept of the social regulation of emotion. The intervention is designed to improve well-being in individuals with MS by leveraging participants'…
- Trial name
- NCT03951974
- Testing
- Social Emotion Regulation Strategy Development, Control
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Kessler Foundation
Bipolar Disorder, Mania
Anti-Estrogens - A Potential Treatment for Bipolar Affective Disorder in Women?
OBJECTIVE: To test the use of two adjunctive hormonal agents in a 28 day three-arm, double-blind, placebo-controlled study in the treatment of acute mania/hypomania.
- Conditions
- Bipolar Disorder, Mania, Schizoaffective Disorder
- Trial name
- NCT00206544
- Testing
- Tamoxifen, Progesterone
- Where
- Australia
- Volunteers
- 51 people
- Sponsor
- The Alfred
Bipolar Affective Disorder
rTMS in the Treatment of Bipolar Depression
Bipolar affective disorder (BPAD) is: A serious mental illness Estimated to be present in as high as 6.4% of the population in Western populations Associated with considerable disability and high morbidity.
- Trial name
- NCT00436020
- Testing
- TMS
- Where
- Australia
- Volunteers
- 51 people
- Sponsor
- Bayside Health
Diabetes Mellitus, Depression
Behavioral Activation Therapy for Rural Veterans With Diabetes and Depression
This clinical trial will compare the effectiveness of the Healthy Outcomes through Patient Empowerment (HOPE) intervention to enhanced usual care (EUC) for diabetes and depression at 6 and 12 month follow-up.
- Trial name
- NCT01572389
- Testing
- Healthy Outcomes through Patient Empowerment (HOPE), Enhanced Usual Care
- Where
- United States
- Volunteers
- 225 people
- Sponsor
- VA Office of Research and Development
Lower Back Pain Chronic, Non Specific Chronic Low Back Pain
Interoceptive Awareness, Physical Activity, Body Awareness and Emotional Status in Individuals With Non-Specific Chronic Low Back Pain
This observational cross-sectional study aims to examine the relationships between interoceptive awareness, physical activity level, body awareness, emotional status, and pain intensity in individuals with non-specific chronic…
- Trial name
- NSCLBP-AWARE (NCT07275255)
- Volunteers
- 130 people
- Sponsor
- Istinye University
Stroke, Motor Disorders
Virtual Reality Training Affects on Motor Functions and Mental Health in Stroke Patients
In our study, we tested the hypothesis of the safe effect applicability of motor training in the immersion high-tech polymodal VR system not only on the parameters of balance, gait, and motor status of the patient, but also on…
- Conditions
- Stroke, Motor Disorders, Affective Symptoms, Gait Disorder, Sensorimotor
- Trial name
- NCT04681235
- Testing
- Training on VR
- Where
- Russia
- Volunteers
- 34 people
- Sponsor
- Federal Center of Cerebrovascular Pathology and Stroke, Russian Federation Ministry of Health
Fatigue Syndrome, Chronic, Healthy
Study of the Hypothalmic-Pituitary-Adrenal (HPA) Axis and Its Role in Major Depression
Major depression represents a major public health problem worldwide and in the U.S. Fifteen percent of the U.S. population has depression at some point in life (40 million individuals).
- Conditions
- Fatigue Syndrome, Chronic, Healthy, Mood Disorders
- Trial name
- NCT00001479
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Borderline Personality Disorder
Guanfacine to Treat Borderline Personality Disorder
This study is designed to investigate whether guanfacine (Tenex) is an effective treatment for borderline personality disorder (BPD), an illness often characterized by unstable mood and impulsive aggression.
- Trial name
- NCT00358969
- Testing
- guanfacine (Tenex)
- Where
- United States
- Sponsor
- Icahn School of Medicine at Mount Sinai
Schizophrenia, Alexithymia
The Effect of Recognition and Expression of Emotions Program Applied to Schizophrenia Patients
As a result of the positive and negative symptoms that occur in schizophrenia, patients with schizophrenia may experience negative emotions more frequently than individuals with other mental problems.
- Conditions
- Schizophrenia, Alexithymia, Emotion, Expressed
- Trial name
- NCT05662137
- Testing
- Emotions Recognition and Expression
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Sinop University
Affective Spectrum Symptoms
Gene-environment Interactions in Families With Adolescents (Gen-omgevingsinteracties in Gezinnen Met Adolescenten)
English: The main purpose of this study is to investigate the developmental trajectories of parents and adolescents in the Flemish region of Belgium.
- Trial name
- GiGA (NCT05716412)
- Where
- 2 sites in Belgium
- Volunteers
- 1,326 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Sleep Deprivation, Sleep
The Effect of Sleep Deprivation and Recovery Sleep on Emotional Memory and Affective Reactivity
To further understand the impact of acute sleep deprivation and recovery sleep on the processing of emotional information the investigators will address and attempt to answer three questions, (i) how both undisturbed sleep and…
- Trial name
- NCT03767426
- Testing
- Sleep Deprivation, Daytime nap
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Breast Cancer, Emotional Disturbances
Improving Emotion Regulation at the End of Breast Cancer Treatment
The end of treatment marks the beginning of a challenging period for breast cancer patients. While this period often provokes a sense of relief, it can also be a source of apprehension and vulnerability regarding the future.
- Conditions
- Breast Cancer, Emotional Disturbances, Emotional Dysfunction, Anxiety Depression
- Trial name
- NCT03336827
- Testing
- Cognitive-Behavioral Group Therapy and Hypnosis
- Where
- Belgium
- Volunteers
- 120 people
- Sponsor
- Université Libre de Bruxelles
Schizophrenia; Psychosis, Schizophrenia and Related Disorders
Accelerated rTMS for Psychomotor Slowing
The goal of this clinical trial is to optimize the treatment of psychomotor slowing in patients with schizophrenia using Transcranial Magnetic Stimulation (TMS).
- Conditions
- Schizophrenia; Psychosis, Schizophrenia and Related Disorders, Schizo Affective Disorder, Brief Psychotic Disorder
- Trial name
- ATMSSlowing (NCT06134661)
- Testing
- cTBS (continuous Theta Burst Stimulation)
- Where
- Switzerland
- Volunteers
- 25 people
- Sponsor
- University of Bern
Mental Disorders, Schizophrenia
Web-Based Weight Management for Individuals With Mental Illness
Obesity and physical inactivity have become serious problems for individuals with mental illness, resulting in increased rates of chronic disease, premature death, and substantial health care costs.
- Conditions
- Mental Disorders, Schizophrenia, Affective Disorders, Psychotic, Overweight
- Trial name
- eWellness (NCT01324973)
- Testing
- eWellness
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of California, Los Angeles
Interoceptive Awareness, Interoception
Haptic Feedback for Improved Interoceptive Awareness and Mental Well-being
This study investigates the relationship between heart-beat haptic feedback on interoceptive awareness and mental-wellbeing. Previous research showed non-significant results in short-term emotion regulation tasks when given…
- Conditions
- Interoceptive Awareness, Interoception, Alexithymia, Anxiety
- Trial name
- NCT07809958
- Testing
- Heart rate feedback from smartwatch
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Massachusetts Institute of Technology
Learning Disabilities
Affective Learning in Disabled Health Training
This study was conducted to determine the effect of the learning method based on transformative learning theory to improve sensitivity towards the disabled on the empathic tendency, attitude and alexithymia levels of nursing…
- Trial name
- NCT04365894
- Testing
- Transformative learning theory
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Istanbul Saglik Bilimleri University
Rumination, Major Depressive Disorder
Decoding and Modulating Affective Brain States
The research study is being conducted to study brain patterns of negative emotion and develop personalized brain stimulation protocols to disrupt these patterns with transcranial magnetic stimulation (TMS).
- Conditions
- Rumination, Major Depressive Disorder, Anxiety
- Trial name
- NCT05437705
- Testing
- Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Pennsylvania
Affective Psychosis, Bipolar, Mania
Non-interventional Study of Ziprasidone in the Treatment of Bipolar and Schizoaffective Disorders.
Assessment of ziprasidone safety and efficacy in the treatment of bipolar and schizoaffective disorders.
- Conditions
- Affective Psychosis, Bipolar, Mania, Manic-Depressive Psychosis
- Trial name
- NCT00454883
- Testing
- ziprasidone
- Volunteers
- 379 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Schizophrenia, Schizo Affective Disorder
Targeting Auditory Hallucinations With Alternating Current Stimulation
Investigating the effects of non-invasive transcranial alternating current stimulation (tACS) as a treatment for auditory hallucinations in patients with schizophrenia.
- Trial name
- STILL3 (NCT03221270)
- Testing
- tACS treatment week, Maintenance tACS
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of North Carolina, Chapel Hill
Epilepsy, Depression
Affective Processing in Depression and Epilepsy
The goal of this study is to determine whether there are unique markers on neuroimaging that are associated with depression in epilepsy.
- Conditions
- Epilepsy, Depression, Healthy
- Trial name
- NCT00855725
- Testing
- fMRI, Hamilton Depression Rating Scale, Beck's Depressive Inventory
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Northwell Health