Clinical trials: Symptoms, Affective
Schizophrenia
Efficacy and Safety of Quetiapine in Treating Affective Symptoms of Patients With First-episode psychosis-a Pilot Study
The purpose of this study is: To investigate whether a treatment with quetiapine for six months in patients with first-episode psychosis may be effective in treating depressive symptoms.
- Trial name
- NCT00511277
- Testing
- Seroquel®
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- Institut fuer anwendungsorientierte Forschung und klinische Studien GmbH
Self Efficacy, Occupational Stress
Meta Self-efficacy Internet Intervention to Improve Work Self-efficacy and Occupational Well-being in Young Employees
This randomized controlled trial aims to test whether enhancing meta self-efficacy through a self-guided internet intervention improves young employees' work self-efficacy and occupational well-being.
- Conditions
- Self Efficacy, Occupational Stress, Well-Being, Psychological, Work Related Stress
- Trial name
- NCT06944990
- Testing
- Meta self-efficacy internet intervention
- Where
- Poland
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University of Social Sciences and Humanities, Warsaw
Bipolar Disorder
The MONARCA Project (MONitoring, treAtment and pRediCtion of bipolAr Disorder Episodes)
Bipolar disorder is associated with a high risk of relapse and hospitalisation and many patients do not recover to previous psychosocial function.
- Trial name
- MONARCA (NCT01446406)
- Testing
- MONARCA, NON-MONARCA
- Where
- Denmark
- Volunteers
- 78 people
- Sponsor
- Psychiatric Centre Rigshospitalet
Chronic Pain, Quality of Life
The Effect of Aerobic Exercise in Alexithymic Individuals With Chronic Pain
It was aimed to investigate the effect of aerobic exercise on pain, alexithymia level and quality of life in young alexithymic individuals with chronic pain.
- Conditions
- Chronic Pain, Quality of Life, Alexithymia
- Trial name
- NCT05460806
- Testing
- Aerobic Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- KTO Karatay University
Overweight and/or Obesity, Overweight and Obese Adults
Psychophysiological and Cognitive Responses to Low-Volume High-Intensity Interval Exercise in Overweight-to-Obese Adults
This study aims to explore how stress-related hormones and psychological traits influence people's feelings and perceptions during a short and intense form of exercise called low-volume high-intensity interval exercise (Lv-HIIE).
- Trial name
- PSYCOG-HIIE (NCT07276308)
- Testing
- Low-Volume High-Intensity Interval Exercise (Lv-HIIE)
- Where
- Malaysia
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia
Bipolar Disorder, Involutional Depression
Study of the Psychological Development of Children of Parents With and Without Affective Disorders
This research study is the continuation of a study started more than 20 years ago. The study was designed to explore the effect that depressed parents have on their children and to better understand the factors that contribute to…
- Conditions
- Bipolar Disorder, Involutional Depression, Mood Disorder
- Trial name
- NCT00001170
- Where
- United States
- Volunteers
- 1,045 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Opioid Use, Affective Symptoms
Affective Effects of Pre-surgery Opioids: a Randomized, Doubleblind Placebo-controlled Trial
1. To investigate and compare the affective short-term effects of opioid drugs: morphine, oxycodone and fentanyl, administered to the patients before the induction of general anesthesia. 2.
- Trial name
- AFFECT2 (NCT05639712)
- Testing
- Morphine 2.5 mg i.v., Morphine 5 mg i.v., Morphine 10 mg i.v.
- Where
- Norway
- Volunteers
- 1,014 people
- Sponsor
- Oslo University Hospital
Anxiety Disorder, Depression
Minocycline Hydrochloride in Reducing Chemotherapy Induced Depression and Anxiety in Patients With Stage I-III Breast Cancer
This randomized clinical trial studies how well minocycline hydrochloride works in reducing chemotherapy induced depression and anxiety in patients with stage I-III breast cancer.
- Conditions
- Anxiety Disorder, Depression, Recurrent Breast Cancer, Stage IA Breast Cancer
- Trial name
- NCT02203552
- Testing
- minocycline hydrochloride, laboratory biomarker analysis, Questionnaire administration
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
Inactivity, Physical, Overweight (BMI > 25)
Effect of Low Volume Sprint Interval Training on Cardiorespiratory Fitness
Low levels of physical activity (PA) are related to poor health and greater risk of premature death in adults. Lack of time is cited as a primary barrier to partaking in PA.
- Conditions
- Inactivity, Physical, Overweight (BMI > 25), Healthy Participants
- Trial name
- NCT07328568
- Testing
- High intensity interval training
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- California State University, San Marcos
Emotional Disturbances
Small Children, Big Emotions
The study is a randomized controlled trial evaluating the clinical and cost-effectiveness of Tuning in to Kids (TIK) compared to treatment as usual (TAU).
- Trial name
- NCT04108949
- Testing
- Tuning in to Kids, Treatment as usual
- Where
- 3 sites in Norway
- Volunteers
- 20 people
- Sponsor
- University Hospital, Akershus
Neurocognitive Disorders, Cognitive Dysfunction
A Pilot Randomized Controlled Trial: CoINTEGRATE
The purpose of this study is to examine the feasibility of comprehensive multimodal individually tailored Cognitive Behavioral Therapy (CBT), Cognitive Rehabilitation Therapy (CRT), and modifiable lifestyle sessions.
- Conditions
- Neurocognitive Disorders, Cognitive Dysfunction, Traumatic Brain Injury, Multiple Sclerosis
- Trial name
- CoINTEGRATE (NCT05732285)
- Testing
- CRT, CBT, Modifiable lifestyle factors
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Michigan
Suicidal Ideation, Major Depressive Disorder
Low Amplitude Pulse Seizure Therapy Versus Standard Ultra-Brief Right Unilateral Electroconvulsive Therapy
This protocol proposes an initial randomized clinical trial that includes all patients with suicidal ideation (SI) at baseline, and with SI as the primary outcome measure to examine whether Right Unilateral Low-Amplitude Pulse …
- Conditions
- Suicidal Ideation, Major Depressive Disorder, Schizo Affective Disorder, Bipolar Disorder
- Trial name
- LAP-ST vs ECT (NCT06529029)
- Testing
- Sigma-Stim, RUL LAP-ST (Low-Amplitude Pulse Seizure Therapy - Right Unilateral)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Michigan State University
Emotional Well-being, Psychological Stress
Feasibility of a Mind-Body Intervention for Optimism
This pilot study tests whether three brief mind-body activities can be delivered remotely to midlife adults, and whether they show early signs of improving cardiovascular health, emotional well-being, and stress.
- Conditions
- Emotional Well-being, Psychological Stress, Cardiovascular Risk
- Trial name
- NCT07862478
- Testing
- Emotional Well-Being Writing, Chair-Assisted Squats, Slow-Paced Breathing
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Penn State University
Epilepsy, Depression
Affective Processing in Depression and Epilepsy
The goal of this study is to determine whether there are unique markers on neuroimaging that are associated with depression in epilepsy.
- Conditions
- Epilepsy, Depression, Healthy
- Trial name
- NCT00855725
- Testing
- fMRI, Hamilton Depression Rating Scale, Beck's Depressive Inventory
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Chronic Low Back Pain, Radiculopathy
Effect of Alexithymia on Treatment Response to Transforaminal Epidural Steroid Injections in Chronic Low Back Pain
Low back pain and lumbosakral radiculopathy represent common clinical challenges substantially diminishing health-related quality of life and work productivity.
- Conditions
- Chronic Low Back Pain, Radiculopathy, Alexithymia
- Trial name
- NCT07828132
- Testing
- Psychometric Assessment and Clinical Follow-up Battery
- Volunteers
- 60 people
- Sponsor
- Marmara University
Psoriasis
Clinical Assessment and Psychosocial Impact of Psoriasis
The purpose of this study is to explore the impact of plaque psoriasis on the different dimensions of patient life including psychological disorders, different types of addictions, and their consequences on health-related quality…
- Trial name
- EPIDEPSO (NCT01964443)
- Where
- 48 sites in Austria, Belgium and 10 more
- Volunteers
- 719 people
- Sponsor
- Janssen Pharmaceutica N.V., Belgium
Kidney Transplant Rejection
Expressive Writing in Kidney Transplant Patients
Kidney transplantation is a replacement treatment for chronic renal failure that improves quality of life. However, it can be experienced as traumatic in relation to the changes it entails in terms of lifestyle, redefinition of…
- Trial name
- EWKTP (NCT04143178)
- Testing
- Expressive Writing, Neutral Writing
- Where
- Italy
- Volunteers
- 35 people
- Sponsor
- University of Roma La Sapienza
Memory Losses, Amnesia-Memory Loss
Effect of Affective Content on Drug Induced Amnesia of Episodic Memory
The purpose of this research is to understand how some of the drugs commonly used in anesthesia impair memory. We are particularly interested in whether the emotion associated with a memory influences how well these drugs are…
- Trial name
- NCT00142493
- Testing
- Propofol, Thiopental Sodium, Dexmedetomidine Hydrochloride
- Where
- United States
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Depressive Illness
Add-on to Cognitive, Event-Related Potentials (ERP) and Electroencephalogram (EEG) Asymmetry in Affective Disorders
Depressed patients unremitted after monotherapy with citalopram or bupropion will remit following six weeks treatment with the combination of citalopram and bupropion.
- Trial name
- NCT03278938
- Testing
- bupropion, citalopram
- Where
- United States
- Sponsor
- New York State Psychiatric Institute
Diabetes Mellitus, Depression
Psychological Variables and Hyperglycemia in Diabetes Mellitus
The investigators want to try the psycho educational method "The Affect School with Script Analysis and the physiotherapeutic mind-body therapy "Basal Body Awareness Therapy in patients with diabetes, high HbA1c and psychological…
- Conditions
- Diabetes Mellitus, Depression, Alexithymia, Anxiety
- Trial name
- ALEXIDIAB (NCT01714986)
- Testing
- Affect School, Body Awareness Therapy
- Sponsor
- Lund University