Clinical trials: Symptoms, Behavioral
Military Personnel, Family Members
Telephone Support During Overseas Deployment for Military Spouses
Deployment impacts both service member and family, and the cost can be high. Spouses' reactions to deployment may include emotional distress, loneliness, anticipatory fear or grief, somatic complaints, and depression.
- Conditions
- Military Personnel, Family Members, Resilience, Psychological, Deployment
- Trial name
- NCT01828983
- Testing
- Telephone support groups, Education webinars
- Where
- United States
- Volunteers
- 161 people, healthy volunteers welcome
- Sponsor
- Memphis VA Medical Center
End-stage Renal Disease (ESRD)
Effect of Lifestyle Intervention in Patients With Chronic Kidney Disease on Fitness and Immune Function
To assess the efficacy of a 6-month lifestyle intervention in patients with end-stage renal disease(ESRD), we plan to conduct a self-controlled clinical trial. 34 participants receiving chronic HD will be enrolled.
- Trial name
- NCT05649657
- Testing
- Cyclic aerobic and resistance training
- Where
- Taiwan
- Volunteers
- 34 people
- Sponsor
- Chang Gung Memorial Hospital
Pulmonary Disease, Chronic Obstructive, Cigarette Smoking
E-Visit for COPD and Smoking Cessation
The goal of this work is to develop, refine, and pilot test an electronic visit (e-visit) to: 1) deliver smoking cessation treatment to adults at risk for COPD and 2) to improve rates of COPD early detection and accurate…
- Conditions
- Pulmonary Disease, Chronic Obstructive, Cigarette Smoking, Telemedicine
- Trial name
- NCT04155073
- Testing
- smoking cessation, early COPD detection, electronic visit, Treatment As Usual
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- Medical University of South Carolina
Prolonged Grief Symptoms
Ericksonian Hypnosis Versus CBT for Prolonged Grief
Effects of Ericksonian Hypnotherapy Versus Cognitive Behavioral Therapy on Prolonged Grief Among University Students in Istanbul: A Randomized None-clinical Controlled Trial This randomized controlled trial explores the efficacy…
- Trial name
- NCT06398886
- Testing
- Ericksonian Hypnosis, Cognitive Behavioral Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Istanbul Nisantasi University
Symptoms of Depression and Anxiety
Mindfulness Intervention Using Virtual Reality in Older Adults With Symptoms of Anxiety and Depression in Ecuador
The availability of affordable hardware and rapidly growing content that can be freely accessed in the public domain raises the possibility of VR being used across the world globally and, in a very broad range of settings…
- Trial name
- NCT06219642
- Testing
- Mindfulness using virtual reality
- Where
- Ecuador
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Universidad San Francisco de Quito
Psychological Distress, Anxiety
Acceptance and Commitment Therapy for Older Adults
Title: Acceptance and Commitment Therapy for older adults experiencing psychological distress: A hermeneutic single case efficacy design (HSCED) series.
- Conditions
- Psychological Distress, Anxiety, Depression
- Trial name
- NCT04280445
- Testing
- Psychological therapy
- Where
- United Kingdom
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- University of Lincoln
Cough, Chronic Disease
Internet-Behavioral Cough Suppression Therapy
The goal of this randomized, placebo-controlled, clinical trial is to develop and test the efficacy of an Internet-based behavioral intervention for refractory chronic cough.
- Trial name
- NCT05770401
- Testing
- Internet-Behavioral Cough Suppression Therapy
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- University of Montana
Binge Eating, Eating Disorders in Adolescence
Cognitive Behavioral Therapy for Adolescent Binge Eating and Loss of Control Eating
This study will develop and test a cognitive-behavioral intervention for adolescents with binge/loss-of-control eating.
- Conditions
- Binge Eating, Eating Disorders in Adolescence, Overweight and Obesity
- Trial name
- NCT04088097
- Testing
- Cognitive-Behavioral Therapy for Adolescent Binge/Loss-of-Control Eating, Control Condition
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Yale University
Anxiety, Depression
Effectiveness of CES on Emotional and Cellular Wellbeing
The investigators aim to use a CES (cranial electrotherapy stimulation) intervention to improve emotional well-being by reducing symptoms of anxiety and depression and to assess for changes in markers of cellular health …
- Trial name
- NCT03369418
- Testing
- Alpha-Stim Active, Alpha-Stim Inactive
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Depression
[11C]-(R)-Rolipram to Measure cAMP Signaling Before and After Ketamine
Background: Major depressive disorder (MDD) may have many underlying causes. One theory is that brain cells with low levels of a molecule called cyclic AMP (cAMP) may cause depression.
- Trial name
- NCT05522673
- Testing
- 11(R)-rolipram
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- National Institute of Mental Health (NIMH)
Depression
Treatments for Improving Mood in Depressed Teens-3
Phase 3 is a randomized clinical trial of yoga vs group Cognitive Behavioral Therapy (CBT) for adolescents with depression.
- Trial name
- TeenThrive (NCT03831360)
- Testing
- Yoga, Group CBT
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Brown University
Cigarette Smoking
Behavioral Activation Intervention for Smoking Cessation in Smokers With Depressive Symptoms
Depression related vulnerabilities are highly comorbid with smoking behavior and dramatically reduce cessation rates among both community and clinical samples.
- Trial name
- NCT01199380
- Testing
- Standard Treatment, Behavioral Activation Treatment for Smoking, Transdermal Nicotine Patch
- Where
- United States
- Volunteers
- 184 people
- Sponsor
- University of Maryland, College Park
Tobacco Use Disorder, Oral Nicotine Pouch Use
Switching to Potential Reduced Exposure Products in Adult Smokers
This study aims to assess the feasibility, acceptability, and the potential harm reduction of switching to potentially lower risk, oral nicotine pouches in adult smokers.
- Conditions
- Tobacco Use Disorder, Oral Nicotine Pouch Use, Smoking Behaviors, Harm Reduction
- Trial name
- ZYN (NCT04250727)
- Testing
- ZYN
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Yale University
Depressive Disorder, Anhedonia
Study to Treat Major Depressive Disorder With a New Medication
This project is designed to examine the neuronal KCNQ2/3 potassium (K+) channel subtype as a novel treatment target for mood disorders through the administration of the KCNQ-selective channel opener ezogabine (Potiga…
- Trial name
- NCT03043560
- Testing
- Ezogabine
- Where
- 2 sites in United States
- Volunteers
- 45 people
- Sponsor
- James Murrough
Chronic Pain
Cognitive Behavioral Therapy and Chronic Pain Self-Management Within the Context of Opioid Reduction: The EMPOWER Study
The proposed study will fill several critical gaps in evidence that are preventing patients and physicians from making informed decisions about their pain care.
- Trial name
- NCT03445988
- Testing
- Cognitive Behavioral Therapy, Chronic Pain Self Management Program, Taper Only
- Where
- United States
- Volunteers
- 1,462 people
- Sponsor
- Stanford University
Chronic Illness
Pilot Study to Improve Care Coordination
The purpose of this study is 1) to learn how VA patients can help share their health information between their VA providers and providers outside the VA and 2) if sharing this information is useful to providers and improves care…
- Trial name
- NCT02386189
- Testing
- Patient Care Coordination Training
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- VA Office of Research and Development
Anxiety, Depression
Improving Adherence to Homework During Therapy
The purpose of this study is to expand Adhere.ly- a simple, HIPAA-compliant, web-based platform to help therapists engage clients in practicing therapeutic skills between sessions (homework) during mental health treatment by…
- Conditions
- Anxiety, Depression, Depression/Anxiety
- Trial name
- Adherely STTR (NCT05866185)
- Testing
- Therapy, Therapy + Adhere.ly
- Where
- United States
- Volunteers
- 79 people
- Sponsor
- University of South Florida
Attention Deficit Hyperactivity Disorder, Dyslexia
Effects of Atomoxetine on Brain Activation During Attention & Reading Tasks in Participants With ADHD & Comorbid Dyslexia
This study will evaluate the effects of atomoxetine on brain activation during attention and reading tasks via functional Magnetic Resonance Imaging (fMRI) in participants ages 10 to 16 years old with ADHD and comorbid dyslexia
- Trial name
- NCT00716274
- Testing
- Atomoxetine
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Eli Lilly and Company
Sexual Dysfunctions, Psychological, Depression
12 Week Safety Trial of Flibanserin in Depressed Women Taking an SSRI or SNRI With Decreased Sexual Desire and Distress
The current trial will explore the safety of flibanserin in combination with Selective Serotonin Reuptake Inhibitors or Norepinephrine Serotonin Reuptake Inhibitors in a representative population of women with depressive and…
- Trial name
- NCT01040208
- Testing
- flibanserin 50 mg to 100 mg qhs, flibanserin 100 mg qhs
- Where
- 42 sites in United States
- Volunteers
- 111 people
- Sponsor
- Sprout Pharmaceuticals, Inc
Dementia, Alzheimer Disease
Assessing Acceptability, Cost, and Efficacy of STELLA-Support Via Technology
STELLA (Support via Technology Living and Learning with Advancing Alzheimer's disease and related dementias) is a multicomponent video-conference based intervention that aims to help family members caring for persons of dementia…
- Conditions
- Dementia, Alzheimer Disease, Caregiver Burnout, Family Members
- Trial name
- STELLA (NCT04335110)
- Testing
- STELLA (Support via TEchnology: Living and Learning with Advancing Alzheimer's disease and related dementias)
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Oregon Health and Science University
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