Clinical trials: Symptoms, Behavioral
Obesity
Motivating Increases in Physical Activity for Prevention of Weight Regain After Metabolic Bariatric Surgery
The goal of this clinical trial is to learn if a psychological intervention can increase regular physical activity to help prevent weight regain after metabolic bariatric surgery in adults.
- Trial name
- NCT06484621
- Testing
- Acceptance and Commitment Therapy-Based Physical Activity Intervention, Physical Activity Education Control
- Where
- United States
- Volunteers
- 164 people
- Sponsor
- Hartford Hospital
Anxiety, Depression
Evaluation of the Medical Psychiatry Alliance Senior's Outpatient Collaborative Care Project
This study evaluates the effectiveness of a collaborative care model designed to treat frail seniors with both a mental (anxiety and/or depression) and a physical health condition impacting function with a comparison group that…
- Trial name
- MPASOP (NCT03617614)
- Testing
- Collaborative Care Model, Mood Consultation
- Where
- 2 sites in Canada
- Volunteers
- 13 people
- Sponsor
- Trillium Health Centre
Hemorrhoids Second Degree, Hemorrhoids Third Degree
Comparison of Laser Hemorrhoidoplasty Versus Conventional Milligan Morgan Hemorrhoidectomy in Grade II and III Hemorrhoids
Hemorrhoidal disease is one of the most common anorectal disorders. Conventional Milligan Morgan Hemorrhoidectomy remains the standard treatment but is associated with considerable postoperative pain.
- Conditions
- Hemorrhoids Second Degree, Hemorrhoids Third Degree, Internal Hemorrhoids
- Trial name
- LHP-MMH (NCT07678814)
- Testing
- Laser Hemorrhoidoplasty, Milligan Morgan Hemorrhoidectomy
- Where
- Pakistan
- Volunteers
- 96 people
- Sponsor
- Allama Iqbal Medical College
Suicide, Attempted
Male Suicide and Metacognition
Suicide is the act of killing oneself and accounts for one death every 40 seconds around the world. In the UK, over 75% of suicides are completed by men.
- Trial name
- MSM (NCT04796116)
- Where
- United Kingdom
- Volunteers
- 15 people
- Sponsor
- Greater Manchester Mental Health NHS Foundation Trust
Chronic Obstructive Pulmonary Disease, Anxiety
"Consultation Liaison and Integrated Care for COPD Patients With Psychiatric Co-Morbidity"
Chronic obstructive pulmonary disease (COPD) stands out among chronic diseases with its high and rising prevalence and mortality, poor quality of life, high re-hospitalization rates and societal burden of care.
- Conditions
- Chronic Obstructive Pulmonary Disease, Anxiety, Depression
- Trial name
- COPD_HSRG (NCT01644916)
- Testing
- Integrated care, Usual control
- Where
- Singapore
- Volunteers
- 295 people
- Sponsor
- National University of Singapore
Depression
Safety and Efficacy of EVT 101 in Treatment-Resistant Depression
This study is a 4-week, randomized, double-blind, parallel-group, placebo-controlled monotherapy study in patients with treatment-resistant major depression.
- Trial name
- NCT01128452
- Testing
- EVT 101
- Where
- 14 sites in United States
- Volunteers
- 8 people
- Sponsor
- Janssen Research & Development, LLC
Depression, Psychological Distress
A Pilot Study of the Effect of Personalized Depression Risk Communication
Depression is a highly prevalent and disabling mental health problem. It is associated with significant morbidity and mortality and it has a significant economic impact.
- Trial name
- NCT04519892
- Testing
- PDRC, Coach guidance
- Where
- Canada
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Dementia
Individualized Music Playlist Based on ISO Principle for De-escalation of Agitation in Dementia
The goal of this clinical trial is to evaluate the efficacy of an Individualized Music Playlist (InMP) composed of preferred music genres sequenced according to the ISO-Principle, for the immediate de-escalation of agitation in…
- Trial name
- NCT06104436
- Testing
- Individualized music playlist, Preferred music, Usual care
- Where
- Hong Kong
- Volunteers
- 81 people
- Sponsor
- The Hong Kong Polytechnic University
Psoriatic Arthritis, Depression
Evaluating the Role of IL-17 as an Orchestrator of Peripheral-central Cross Talk in Depressive Symptoms
The investigators seek clinically actionable understanding of the mechanisms that underlie depression in the context of immune mediated inflammatory diseases (IMIDs), delivered by a focused immune intervention study examining…
- Conditions
- Psoriatic Arthritis, Depression, Psoriatic Plaque
- Trial name
- ELATE (NCT06786936)
- Testing
- Secukinumab, Bimekizumab, Ixekizumab
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- NHS Greater Glasgow and Clyde
Alcohol Drinking
Effect of Glutathione on Blood Alcohol and Hangover Symptoms
Glutathione (a tripeptide of 3 amino acids - glutamic acid, cysteine and glycine) plays a great role in homeostasis, especially as a potent anti-oxidant.
- Trial name
- NCT00127309
- Testing
- Glutathione
- Where
- Thailand
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Piyavate Hospital
Suicide, Mental Health Disorder
A Just-in-time Adaptive Intervention for Suicide Safety Planning in Adolescents
Despite efforts to prevent suicide, US rates are climbing, and suicide is the second leading cause of death amongst youth. Digital tools, especially personal smartphones, are promising avenues to address these issues and can be…
- Conditions
- Suicide, Mental Health Disorder, Anhedonia
- Trial name
- ViraSafeRCT (NCT07348666)
- Testing
- ViraSafe: Treatment pushes, BRITE
- Where
- 3 sites in United States
- Volunteers
- 100 people
- Sponsor
- Ksana Health
Stress Disorders, Post-Traumatic, Depression
Veteran Health Study
The purpose of The Veteran Health Study (CSP #569) is to better understand the mental and physical health of veterans as they get older.
- Conditions
- Stress Disorders, Post-Traumatic, Depression, Diabetes, Cardiovascular Disease
- Trial name
- NCT01175629
- Where
- United States
- Volunteers
- 7,568 people
- Sponsor
- US Department of Veterans Affairs
Childbirth
Regulated Expiratory Breathing Method During Childbirth
The factors affecting the rate of primary caesarean section births are complex, and identifying interventions to reduce this rate is challenging.
- Trial name
- NCT04219631
- Testing
- expiration mouthpiece used during breathing exercises to ensure a constant ventilatory flowrate.
- Where
- Tunisia
- Volunteers
- 120 people
- Sponsor
- University Tunis El Manar
Obesity
Family-based Outcome Results
Many obesity related risk factors are strikingly apparent in minority populations. Mexican-American children have the highest rates of overweight.
- Trial name
- NCT04132245
- Testing
- behavioral intervention, Obesity prevention intervention trial
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Sudden Cardiac Death
CIQTP Prolongation : Role and Mechanism in Sudden Cardiac Death
Despite major progress in molecular and phenotypic characterization of primary electrical disorders, many (aborted) sudden cardiac deaths (SCD) occur in young victims without identifiable abnormalities.
- Trial name
- IQARE-SCD (NCT03387072)
- Testing
- Non interventional study
- Where
- 4 sites in France
- Volunteers
- 394 people
- Sponsor
- Nantes University Hospital
Elderly, Muscle Loss
Effect of Lactobacillus Paracasei PS23 on Improving Aging and Muscle Loss in the Elderly
This study refers to the supplementation of PS23 in human experiments to help the elderly maintain muscle mass, delay muscle loss, promote physical activity, and delay the occurrence of disability and debilitation in elderly…
- Conditions
- Elderly, Muscle Loss, Depression, Anxiety
- Trial name
- NCT06062472
- Testing
- Probiotics, heat-treated of Lactobacillus paracasei HT-PS23
- Where
- Taiwan
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- Chi-Chang Huang
Tinnitus, Hearing Loss
Investigating Disinhibitory Brain Mechanism in Tinnitus and Hearing Loss
Tinnitus, the perception of sound in the absence of an external acoustic stimulus. Tinnitus is often perceived inside the head rather than the ear and is a common condition with a prevalence estimated between 10 and 15% in…
- Trial name
- IGNITE (NCT04862572)
- Testing
- MRI scanning
- Where
- 3 sites in United Kingdom
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Female, Older Adults
Effect of Green Tea Supplementation in Older Adult Women
Introduction: One of the consequences of aging is the decrease in physical performance which can affect the quality of life of older people.
- Conditions
- Female, Older Adults, Sarcopenia
- Trial name
- GTAW (NCT06289439)
- Testing
- Green tea (Camellia sinensis) 1000 mg as extract
- Where
- Spain
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Valladolid
Cerebral Palsy, Sleep Disorders in Children
Sleep Quality and Caregiver Burden in Children With Cerebral Palsy
Cerebral palsy (CP) is a lifelong condition affecting movement and posture, often requiring substantial care from family members.
- Conditions
- Cerebral Palsy, Sleep Disorders in Children, Caregiver Burden, Sleep Quality
- Trial name
- CP-SLEEP (NCT07168577)
- Where
- Turkey (Türkiye)
- Volunteers
- 61 people
- Sponsor
- Selim Sezikli
Depression, Major Depressive Disorder
The Effects of Wellbutrin (Bupropion) on Residual and Cognitive Symptoms in SSRI-treated Depression
Many people with depression are treated with a serotonin-specific reuptake inhibitor anti-depressant (SSRI) and feel 'better'. Although many people feel 'better', they do not feel completely 'well'.
- Conditions
- Depression, Major Depressive Disorder, Unipolar Depression
- Trial name
- NCT00125957
- Testing
- Wellbutrin
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Mclean Hospital
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