Clinical trials: Symptoms, Behavioral
Obesity
Examining Cooking as a Health Behavior
The proposed pilot study will examine cooking as an intervention target for weight control in overweight adults. The study will also examine whether interventions designed to promote cooking at home can increase participants'…
- Trial name
- iChef (NCT03783962)
- Testing
- Active Intervention - Cooking, Demonstrations - Cooking
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Vermont
Bipolar Disorder
Combination Therapy for the Treatment of Bipolar Disorders
This study will compare triple and double drug regimens in the treatment of patients with depression, hypomania, or mania.
- Trial name
- NCT00063362
- Testing
- Lithium, Lamotrigine, Divalproex
- Volunteers
- 49 people
- Sponsor
- University Hospitals Cleveland Medical Center
Alzheimer's Disease, Aphasia
Effect of Repetitive Transcranial Magnetic Stimulation on Language in Alzheimer's Disease
The investigators wish to investigate the efficacy of targeted repetitive transcranial magnetic stimulation (rTMS) on expressive language in patients with Alzheimer's disease (AD).
- Conditions
- Alzheimer's Disease, Aphasia, Dementia
- Trial name
- NCT00814697
- Testing
- Repetitive Transcranial Magnetic Coil Stimulation (rTMS)
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- The New York Memory Services
Obesity, Sarcopenic Obesity
The Physiologic Effects of Intranasal Oxytocin on Sarcopenic Obesity
Obesity is highly prevalent in older adults and is a major cause of sarcopenia and disability in older adults. Although exercise can counteract the effects of obesity and sarcopenia, many have difficulty adhering to an exercise…
- Conditions
- Obesity, Sarcopenic Obesity, Sarcopenia, Aging
- Trial name
- INOSO (NCT03119610)
- Testing
- Oxytocin nasal spray
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Sara Espinoza
Resilience, HIV-1-infection
Testing the Efficacy and Mechanisms of an Adapted Resilience Building Intervention in People Aging With HIV
This study will examine the mechanisms and efficacy of a resilience building intervention in older people living with HIV.
- Conditions
- Resilience, HIV-1-infection, Stress, Psychological
- Trial name
- RISE+ (NCT05314088)
- Testing
- RISE+, Stress Reduction Control
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- University of Alabama at Birmingham
Opioid Use Disorder, Chronic Pain
Computer Based Treatment for Cognitive Behavioral Therapy and Cooperative Pain Education and Self-Management
The investigators plan to develop and pilot test an integrated, web-based cognitive behavioral approach and then conduct a randomized clinical trial evaluating its efficacy relative to standard care in a large and diverse sample…
- Trial name
- IMPACT (NCT05204576)
- Testing
- CBT4CBT COPES
- Where
- 3 sites in United States
- Volunteers
- 160 people
- Sponsor
- Yale University
Aphasia
Exercise as an Adjuvant to Aphasia Therapy
The purpose of the study is to reveal if individuals who participate in aerobic activity demonstrate greater improvement in language abilities than patients who do not participate in aerobic activity.
- Trial name
- NCT01113879
- Testing
- Aerobic exercise, Stretching
- Where
- 2 sites in United States
- Volunteers
- 9 people
- Sponsor
- VA Office of Research and Development
Dementia, Depression
Pilot Study to Examine Health Effects of Daylight Exposure on Dementia Patients
This study is designed to test the hypothesis that an intervention increasing exposure to daylight indoors will reduce depression and other neuropsychiatric symptoms among people living with dementia in long term care facilities.
- Conditions
- Dementia, Depression, Behavior Disorders
- Trial name
- NCT03483896
- Testing
- Daylight Intervention
- Where
- 8 sites in United States
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Premature Birth, Pregnancy Preterm
Engaging Mothers & Babies; Reimagining Antenatal Care for Everyone (EMBRACE) Study
This is a randomized comparative effectiveness study of two forms of enhanced prenatal care among 674 Medi-Cal eligible pregnant individuals in Fresno, California.
- Conditions
- Premature Birth, Pregnancy Preterm, Prenatal Stress, Depression, Anxiety
- Trial name
- EMBRACE (NCT04154423)
- Testing
- Glow! Group Prenatal Care, Individual Prenatal Care with CPSP
- Where
- 2 sites in United States
- Volunteers
- 678 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Premenstrual Syndrome, Menstruation Disturbances
A Treatment Study for Premenstrual Syndrome (PMS)
This study examines the effects of estrogen and progesterone on mood, the stress response, and brain function and behavior in women with premenstrual syndrome.
- Trial name
- NCT00001259
- Testing
- Leuprolide, Estradiol Patches, Progesterone
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- National Institute of Mental Health (NIMH)
Postintensive Care Syndrome, Family Members
Family Support Intervention in Intensive Care Units
Background: Family members of critically ill patients face considerable uncertainty and distress during their close other's intensive care unit (ICU) stay, with about 20-60% of family members experiencing post-traumatic distress…
- Conditions
- Postintensive Care Syndrome, Family Members, Quality of Life, Depression, Anxiety
- Trial name
- FICUS (NCT05280691)
- Testing
- Family Support Intervention (FSI)
- Where
- 12 sites in Switzerland
- Volunteers
- 885 people
- Sponsor
- Rahel Naef
HIV, Sexually Transmitted Diseases
Mobile-Based Application "MyChoices"
This study is testing the acceptability and feasibility of MyChoices, a mobile application (app), to promote HIV testing and pre-exposure prophylaxis (PrEP) uptake among young men who have sex with men (YMSM).
- Conditions
- HIV, Sexually Transmitted Diseases, Pre-exposure Prophylaxis, Risk Reduction
- Trial name
- NCT03179319
- Testing
- MyChoices
- Where
- 2 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Fenway Community Health
Pain, Postoperative
Caffeine and Neurologic Recovery Following Surgery and General Anesthesia
The ongoing opioid epidemic is a public health crisis, and surgical patients are particularly vulnerable to opioid-dependency and related risks. Emerging data suggest that caffeine may reduce pain after surgery.
- Trial name
- NCT03577730
- Testing
- Caffeine Citrate, Dextrose Water
- Where
- United States
- Volunteers
- 71 people
- Sponsor
- University of Michigan
Headache, Migraine
Comparison of a Drug and Placebo in the Prevention of Migraine Headaches
The purpose of this study is to determine whether ethosuximide works better than placebo in the prevention of episodic migraine among veterans.
- Trial name
- NCT01122381
- Testing
- ethosuximide
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- US Department of Veterans Affairs
Depression
Adherence to Antidepressant Treatment in Subjects With Depression
This study aims to determine whether a combination a first-line antidepressant plus "RT2CK17" in a capsule relative to a first-line antidepressant plus placebo in a capsule results in higher rates of medication adherence in…
- Trial name
- NCT03388164
- Testing
- Escitalopram + RT2CK17
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Laureate Institute for Brain Research, Inc.
Obesity, Binge Eating
Study of Behavioral Weight Loss Therapy for Obesity and Binge Eating in Monolingual Hispanic Persons
This is a research study designed to examine the effectiveness of an obesity medication (orlistat) given in addition to behavioral weight loss therapy. Participants will be obese monolingual (Spanish-speaking only) men and women.
- Trial name
- NCT00516919
- Testing
- Xenical + behavioral intervention
- Where
- 2 sites in United States
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Yale University
Depression, Anxiety
Integrating Mindfulness Into the Patient-Centered Medical Home (Phase 2)
Among primary care patients, compare the effectiveness of an 8-week mindfulness-based intervention (Mindfulness Training for Primary Care[MTPC]) vs.
- Conditions
- Depression, Anxiety, Stress Related Disorder, Adjustment Disorders
- Trial name
- MINDFUL-PC-2 (NCT03265600)
- Testing
- Mindfulness Training for Primary Care, 60-minute Introduction to Mindfulness
- Where
- United States
- Volunteers
- 136 people
- Sponsor
- Cambridge Health Alliance
Depression, Psychological Distress
Behavior, Biology and Well-Being Study
The central aim of this study is to test the efficacy of the Healthy Minds Program (HMP) app, an intervention designed to promote well-being.
- Trial name
- BeWell (NCT05183867)
- Testing
- Healthy Minds Program
- Where
- United States
- Volunteers
- 1,157 people
- Sponsor
- University of Wisconsin, Madison
Suicide, Attempted, Suicide and Depression
Ketamine Versus Midazolam for Recurrence of Suicidality in Adolescents
This project aims to examine the signal of efficacy of ketamine, a rapidly acting medication shown to decrease suicidality in adults in as short as hours or days, as opposed to weeks.
- Conditions
- Suicide, Attempted, Suicide and Depression, Suicide Threat
- Trial name
- TASK (NCT04592809)
- Testing
- Ketamine Hydrochloride, Midazolam Hydrochloride
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Texas Southwestern Medical Center
Depression
Evaluating Technology Enabled Services in Perinatal Depression
Investigators are evaluating a Technology Enabled Service (TES) to support the treatment of depression in the context of a collaborative care service in obstetrics clinics.
- Trial name
- NCT05525689
- Testing
- IntelliCare, COMPASS-Care
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Northwestern University
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