Clinical trials: Symptoms, Cognitive
Sleep, Stress
The Effects of a Nutrition Supplement on Health Related Quality of Life
The purpose of this study is to evaluate the health related benefits of a superfoods nutrition supplement on health related quality of life.
- Conditions
- Sleep, Stress, Health, Subjective, Inflammation
- Trial name
- NCT04499560
- Testing
- Supplement Drink
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Nutraceuticals Research Institute
Cognitive Symptom, Depression
Psychotropic Drug Use in the Elderly Living in Nursing Homes and the Influence of a Structured Drug Review
The overall aim of this study is to explore if a structured drug review will change clinical symptoms and the psychotropic drugs prescription rate in the elderly living in nursing homes (participants of the study).
- Conditions
- Cognitive Symptom, Depression, Anxiety, Neuropsychiatric Syndrome
- Trial name
- NCT03736577
- Testing
- Drug reviews with NorGeP-NH
- Where
- Norway
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- Ostfold Hospital Trust
Mild Cognitive Impairment, Behavioral Symptoms
The Moderating Roles of Social Support, Coping Resources and Personality and Mediating Role of Self-esteem on the Impact of Cognitive Deficit on Neuropsychiatric Symptoms Among Persons With Mild Cognitive Impairment: A Mixed-method Sequential Explanatory Design
This is a sequential mixed study to test the hypothesized models with seven hypotheses of the relationship between cognitive deficit (subject and objective) and neuropsychiatric symptoms (NPS) among persons with mild cognitive…
- Trial name
- NCT04085107
- Testing
- Face-to-face interviews
- Where
- Hong Kong
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Cognitive Symptom, Pre Senile Dementia
Compensatory Training to Support Brain Healthy Lifestyle Changes in Those at Risk for Alzheimer's Disease
The Researchers are trying to better understand if behavioral interventions can help improve memory compensation and engagement in healthy lifestyle behaviors in those with memory concerns but normal mental status exam.
- Conditions
- Cognitive Symptom, Pre Senile Dementia, Alzheimer Disease
- Trial name
- NCT04118985
- Testing
- Cognitive rehabilitation and health behavior change intervention, Self-implementation
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Dementia, Delirium Superimposed on Dementia
Evaluating the Impact of VR-therapy on BPSD and QoL of Individuals With Dementia Admitted to Hospital
Behavioural and Psychological Symptoms of Dementia (BPSD) (such as aggression, restlessness, agitation, wandering, anxiety, depression) are common to most people with dementia at some point during their illness and represent an…
- Trial name
- VRx-RCT (NCT03941119)
- Testing
- VR-therapy
- Where
- Canada
- Volunteers
- 77 people
- Sponsor
- University Health Network, Toronto
Frail Elderly, Cognitive Impairment
A Community Health Worker Program to Support Rural Older Adults
This study will investigate an intervention delivered by community health workers for older adults with signs of cognitive impairment, mobility loss, and depression in the rural primary care setting.
- Conditions
- Frail Elderly, Cognitive Impairment, Mobility Limitation, Depressive Symptoms
- Trial name
- NCT03843333
- Testing
- Tai Ji Quan: Moving for Better Balance, Behavioral Activation, Resource Navigation
- Where
- 3 sites in United States
- Volunteers
- 39 people
- Sponsor
- University of Vermont
Breast Cancer Survivors, Symptom Management
Effects of an e-Home Based Symptom Management and Mindfulness Training Programme on QoL in Breast Cancer Survivors
Breast cancer is the most common cancer in women in Singapore. Breast cancer survivors usually experience side effects/symptoms after surgery and/or adjuvant chemotherapy and/or radiotherapy such as fatigue, lymphedema, problems…
- Conditions
- Breast Cancer Survivors, Symptom Management, Mindfulness Based Cognitive Therapy, Quality of Life
- Trial name
- NCT02931864
- Testing
- Online mindfulness training, Online symptom management
- Where
- 2 sites in Singapore
- Volunteers
- 172 people
- Sponsor
- National University of Singapore
Cognitive Symptom, Evaluations, Diagnostic Self
French Language Validation of the 5-minutes Montreal Cognitive Assessment (MoCA)
The aim of the study is to validate a french version of the 5 minutes version of the Montreal Cognitive Assessment as compared to the french full version of this test.
- Trial name
- MoCATEL (NCT03232697)
- Testing
- Full version of the Montreal Cognitive Assessment, 5 minutes version of the Montreal Cognitive Assessment
- Where
- France
- Volunteers
- 236 people, healthy volunteers welcome
- Sponsor
- University Hospital, Lille
Sleep, Occupational Stress
A Proactive Intervention Promoting Strategies for Sleep and Recovery in Nurses
Considering the known challenges facing newly graduated nurses, there are possibilities to implement preventive actions. The aim of the current study was to evaluate the effects of a preventive intervention among newly graduated…
- Conditions
- Sleep, Occupational Stress, Fatigue, Behavior, Health
- Trial name
- NCT04246736
- Testing
- Bädda för Kvalitet
- Where
- 7 sites in Sweden
- Volunteers
- 207 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Severe Acute Malnutrition, Cognitive Impairment
Intervening to Repair Cognitive and Behavioural Problems in Adults Exposed to Childhood Malnutrition
Globally, in 2011, 52 million children under 5 years old suffered from acute malnutrition, and a further 165 million children showed evidence of chronic undernutrition or stunting.
- Conditions
- Severe Acute Malnutrition, Cognitive Impairment, Emotional Disturbances
- Trial name
- NCT04053218
- Testing
- Exercise plus omega-3 supplement
- Where
- Jamaica
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The University of The West Indies
Postoperative Cognitive Dysfunction, Postoperative Delirium
Study of Depressive Symptoms Predicting Postoperative Cognitive Dysfunction
Postoperative cognitive dysfunction (POCD) describes a condition where cognitive functions such as attention, perception, concentration, learning, abstract thinking and problem solving are impaired postoperatively.
- Conditions
- Postoperative Cognitive Dysfunction, Postoperative Delirium, Depressive Symptoms
- Trial name
- DeprPOCD (NCT02210312)
- Where
- Germany
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Frail Elderly Syndrome, Bladder Disease
Perioperative Multimodal Care for Cystectomy Frail Patient
Major surgery in the elderly and frail patient is a challenge. Optimal perioperative management is essential for outcome and survival.
- Conditions
- Frail Elderly Syndrome, Bladder Disease, Nutrition Disorders, Cognitive Symptom
- Trial name
- NCT03065348
- Testing
- oral whey protein, Immunonutrition, Carbohydrate Drink
- Where
- Switzerland
- Volunteers
- 4 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Cognitive Changes Due to Organic Disorder (Finding), Dementia
Gerontology Research Programme: The Singapore Longitudinal Ageing Studies (SLAS I & II)
The Gerontology Research Programme (GRP) in the National University Singapore's Department of Psychological Medicine, was formed to coordinate and facilitate the conduct of multi-disciplinary research on in a wide range of…
- Conditions
- Cognitive Changes Due to Organic Disorder (Finding), Dementia, Mild Cognitive Impairment, Frailty
- Trial name
- SLAS (NCT03405675)
- Testing
- SLAS 1, SLAS 2
- Where
- Singapore
- Volunteers
- 6,183 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Cognitive Symptom, Schizophrenia
Touchscreen-based Cognitive Tests in Healthy Volunteers
This phase Ib study aims to evaluate applicability of touchscreen-based cognitive test battery for assessment of ketamine-induced schizophrenia-like cognitive deficits in healthy volunteers.
- Trial name
- NCT03469089
- Testing
- Ketamine 0.58, Ketamine 0.31, Modafinil
- Where
- Finland
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Eastern Finland
Memory Loss, Cognitive Changes
Aging and Estrogen on Cortical Function
This study will focus on how estrogen affects parts of the brain associated with memory and how the effect of estrogen is altered with aging in postmenopausal women.
- Conditions
- Memory Loss, Cognitive Changes, Postmenopausal Symptoms
- Trial name
- NCT01268046
- Testing
- Estradiol oral capsule, transderman estrogen patch
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Efavirenz, Child Behavior
Neuropsychiatric Side Effects of Efavirenz in Children Living With HIV
Efavirenz is among the preferred antiretroviral drugs for HIV-infected children. Increasing evidence shows that central nervous system side-effects in adults are more common than previously thought.
- Conditions
- Efavirenz, Child Behavior, Cognitive Symptom, Medication Adherence
- Trial name
- NCT03227653
- Testing
- Efavirenz, Nevirapine, Lopinavir-Ritonavir Drug Combination
- Where
- 6 sites in Tanzania
- Volunteers
- 144 people
- Sponsor
- Radboud University Medical Center
Cognitive Impairment, Cognitive Decline
Normative Values for the German Version of the Montreal Cognitive Assessment (MoCA)
This observational cohort study in healthy volunteers establishes normative data for the German version of the Montreal Cognitive Assessment (MoCA) and investigates the possible impacts of demographics on the MoCA total score.
- Conditions
- Cognitive Impairment, Cognitive Decline, Cognition Disorders, Cognitive Symptom
- Trial name
- MoCA-Norm (NCT03246269)
- Testing
- MoCA
- Volunteers
- 334 people, healthy volunteers welcome
- Sponsor
- Andreas Monsch
Bipolar Disorder, Cognitive Symptom
A Study of Aerobic Exercise for Patients With Bipolar Disorder
This study will investigate the effects of aerobic exercise on mental states, cognition, BDNF, and long-term outcomes in patients with bipolar disorder.
- Trial name
- NCT03353337
- Testing
- aerobic exercise
- Where
- China
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Guangzhou Psychiatric Hospital
Stroke, Cognitive Symptoms
Cerebral Lesions and Outcome After Cardiac Surgery (CLOCS)
Between 1 and 5 percent of patients who have coronary artery bypass surgery suffer a stroke following surgery, and 30 percent have new brain lesions that do not produce symptoms and are seen only on MRI.
- Trial name
- NCT00391378
- Where
- United States
- Volunteers
- 363 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
HIV - Human Immunodeficiency Virus, Cognitive Symptoms
COMO: Cognition Study With HIV+ Patients (CTNPT 015)
The purpose of this study is to contribute evidence towards the potential to improve cognition in HIV+ individuals experiencing cognitive decline through personalized change in antiretroviral (ARV) medication.
- Trial name
- COMO (NCT02144688)
- Testing
- Change in antiretrovirals
- Where
- Canada
- Volunteers
- 19 people
- Sponsor
- Marie-Josée Brouillette