Clinical trials: Symptoms and Signs
Impaired Glucose Tolerance, Obesity
Enhancing Fitness in Older Pre-diabetic Veterans
This study targets older adults (ages 60 and over) who are overweight (body mass index 25-40) with impaired fasting glucose (100 - 125).
- Conditions
- Impaired Glucose Tolerance, Obesity, Diabetes
- Trial name
- NCT00594399
- Testing
- Physical Activity Counseling
- Where
- United States
- Volunteers
- 302 people
- Sponsor
- US Department of Veterans Affairs
Lung Cancer, Pain
Acupuncture for Post-Thoracotomy Pain
Pain after surgery for lung cancer (thoracotomy) may persist for years and require long-term analgesic use. Prior studies have shown that acupuncture reduces pain and medication use in the early post-operative period after…
- Trial name
- NCT00142532
- Testing
- Acupuncture and Questionnaires
- Where
- United States
- Volunteers
- 162 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Rheumatoid Arthritis, Psoriatic Arthritis
Research Study on the Immunosuppressive Effects of a Cell Therapy Product on PBMC Isolated From Blood of Patients With Inflammatory Rheumatic Diseases
Rheumatic diseases regroup a variety of disorders affecting the locomotor system including joints, muscles, connective tissues and soft tissues around the joints and bones.
- Conditions
- Rheumatoid Arthritis, Psoriatic Arthritis, Spondylarthritis
- Trial name
- NCT03454932
- Testing
- Blood sampling
- Volunteers
- 30 people
- Sponsor
- Bone Therapeutics S.A
Knee Osteoarthritis, Chronic Post Operative Pain
Opioid Reduction in Orthopaedic Surgery (OREOS) - Knees
Knee replacements are the second most common surgery in Canada. Most patients recover very well but research consistently shows that 1 in 5 patients still have pain many months after surgery.
- Trial name
- OREOS (NCT04968132)
- Testing
- Multicomponent opioid reduction and pain management pathway, Standard care
- Where
- Canada
- Volunteers
- 102 people
- Sponsor
- Kim Madden
HİP FRACTURE, Hip Surgery (Lateral Incision)
Perioperative Analgesic Effects of PENG Versus PENG Plus LFCN Block in Hip Surgeries
This study is designed to find the best way to control pain after hip surgery performed through a side (lateral) incision. Two different types of nerve blocks used before the operation will be compared.
- Conditions
- HİP FRACTURE, Hip Surgery (Lateral Incision), Postoperative Pain Management, Analgesia, Postoperative
- Trial name
- NCT07329829
- Testing
- Pericapsular nerve group (PENG) block, Lateral Femoral Cutaneous Nerve (LFCN) Block
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Chronic Obstructive Pulmonary Disease (COPD)
Comparison of Two Positive Expiratory Pressure Devices in Stable COPD Patients
Positive expiratory pressure (PEP) therapy is a device aiding airway clearance and secretion mobilization, also prevent the small airway from collapsing.
- Trial name
- NCT02817529
- Testing
- Pulmonica, RC-Cornet
- Sponsor
- Rush University Medical Center
Endoleak, Aortic Aneurysm, Abdominal
CQDSA in Evaluation of Prognosis After EVAR
Re-hospitalization or re-intervention is sometimes necessary to treat type I and type III endoleaks after EVAR for its persistent increasing of pressure in aneurysm lumen.
- Trial name
- NCT02016131
- Where
- China
- Volunteers
- 49 people
- Sponsor
- Shanghai Zhongshan Hospital
Pulmonary Disease, Chronic Obstructive
Changes in Heart Rate Variability And Heart Rate/Activity Slope After Hospitalization for Acute Exacerbations of COPD
The purpose of this study is to observe the variation in time between heart beats and how heart rate changes during activity evolve after hospitalization for an exacerbation of COPD.
- Trial name
- CHARM COPD (NCT05290831)
- Testing
- VitalPatch
- Volunteers
- 45 people
- Sponsor
- Minneapolis Veterans Affairs Medical Center
CerebroSpinal Fluid (CSF) Leak
The Freiburg Registry on SpontanEous IntercrAnial Hypotension (SIH) & Post-duraL Puncture Headache (PDPH)
Spinal CSF leaks are considered as rare disease. They cause a variety of symptoms, mainly culminating in a chronic headache syndrome. Crucially, yet often disregarded, the disease holds the potential for cure.
- Trial name
- SEAL (NCT06711731)
- Where
- Germany
- Volunteers
- 2,000 people
- Sponsor
- University Hospital Freiburg
Metabolic Syndrome
Effect of MetS* on Cognitive Performance and Physical Activity (Metabolic Syndrome)
Metabolic syndrome (MetS) increases the risk of developing diabetes and cardiovascular disease risk factors that are linked with each other, which is a metabolic dysfunction, which contains a combination of multiple.
- Trial name
- NCT05702437
- Testing
- assessment of cognitive performance
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Postoperative Pain
Effects of Connective Tissue Massage on Pain After Thoracotomy
Pain can be quite severe after thoracic surgery and effective pain control is highly effective in preventing secretion accumulation, atelectasis, infection and hypoxemia.
- Trial name
- NCT05617937
- Testing
- Massage
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Akdeniz University
Jaundice
Prospective Randomized Study of PTC and EUS-guided Drainage of the Bile Duct
At this time, endoscopic retrograde cholangiopancreatography (ERCP) stay the gold standard method to achieve biliary drainage in case of malignant or benign stricture.
- Trial name
- NCT01499537
- Testing
- biliary drainage, EUS guided biliary drainage
- Where
- 3 sites in France, Monaco
- Volunteers
- 65 people
- Sponsor
- Institut Paoli-Calmettes
Disability Physical, Disabilities Multiple
Attitudes Towards Disability of Nursing and Physiotherapy Students
The general objective of this study is to know the attitude towards people with disability of Nursing and Physiotherapy students in the University of Cadiz. This is a descriptive, correlational, transversal and synchronous study.
- Conditions
- Disability Physical, Disabilities Multiple, Disability Hearing, Disability, Vision
- Trial name
- NCT04498637
- Testing
- 'Attitudes towards people with disability Scale'
- Where
- Spain
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Extremadura
Chronic Fatigue Syndrome
Transcutaneous Vagus Nerve Stimulation as a Complementary Therapy to Exercise in Chronic Fatigue
Chronic fatigue is enhanced by adapted physical activity (APA) programs. Patients consulting on St Etienne hospital and suffering from fibromyalgia and long Covid benefit from a 4-6 week APA program, with 2 sessions per week.
- Trial name
- PAF-tVNS (NCT06170645)
- Testing
- APA program, Active transcutaneous VNS
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Osteo Arthritis Knee
Tranexamic Acid in Total Knee Replacement
Multiple intravenous Tranexamic Acid doses can reduce postoperative blood loss and improve the functional outcome in total knee arthroplasty without tourniquet: a randomized controlled study.
- Trial name
- NCT03656445
- Testing
- Tranexamic Acid
- Volunteers
- 180 people
- Sponsor
- Democritus University of Thrace
Opioid Withdrawal, Pain
BRIDGE Device for Treatment of Opioid Withdrawal
The purpose of this study is to prospectively evaluate the effectiveness of the NSS-2 BRIDGE device in reducing the signs and symptoms of acute opioid withdrawal when compared to placebo.
- Conditions
- Opioid Withdrawal, Pain, Craving
- Trial name
- NCT04162145
- Testing
- Active BRIDGE device placement, Inactive BRIDGE device placement
- Where
- 2 sites in United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- BrightView LLC
Obesity
Stepped Care for Weight Loss Maintenance
This study is a 3-group, parallel design, randomized controlled trial (RCT) in approximately 258 adults with obesity that will investigate whether a 16-week behavioral weight loss treatment and a 52-week stepped-care digital…
- Trial name
- NCT06151145
- Testing
- Usual care, SELF, STEP
- Where
- United States
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Cardiovascular Diseases, Obesity
Genetic Epidemiology and Energy Metabolism in Black Girls
To investigate the role of genes and energy metabolism in the pathogenesis of obesity in adolescent Black girls.
- Trial name
- NCT00014872
- Volunteers
- 600 people
- Sponsor
- University of New Mexico
Pain, Postoperative, Cesarean Section
Comparison of TAP, Anterior QL, or ESP Block for Elective Cesarean Section
The purpose of this prospective single center, randomized study is to determine if ultrasound guided Transversus Abdominis Plane (TAP), Quadratus Lumborum (QL), and Erector Spinae Plane (ESP) blocks decrease opioid consumption in…
- Trial name
- NCT03695172
- Testing
- Ropivacaine, TAP block, QL block
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Duke University
Gingival Bleeding, Plaque Induced Gingival Disease
Comparative Study to Evaluate the Efficacy of an Alcohol-free Mouthwash Regimen With CPC+Zn, Flossing and Brushing, and an Alcohol-based Mouthwash Regimen With Essential Oils in Reducing Plaque and Gingivitis.
This is a Phase III, randomized, one-center, parallel group, double blinded, clinical study to evaluate the efficacy of an alcohol-free mouthwash containing CPC+Zn as compared to dental flossing and to rising with an essential…
- Conditions
- Gingival Bleeding, Plaque Induced Gingival Disease, Gingival Diseases, Gingivitis and Periodontal Diseases
- Trial name
- PGMWII (NCT06598072)
- Testing
- Mouthwash CPC+Zn+F, Essential oils mouthwash, Dental floss
- Where
- Mexico
- Volunteers
- 120 people
- Sponsor
- Colgate Palmolive
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