Clinical trials: Symptoms and Signs
Spinal Cord Injuries, Neurogenic Bladder
Intravesical Lactobacillus to Reduce Urinary Symptoms After Spinal Cord Injury
The objectives of the proposed research among this population are: 1) to define clinically meaningful change (i.e. differentiating states of health and illness) with respect to urinary symptoms, urine inflammation, cultivable…
- Trial name
- NCT04373512
- Testing
- Culturelle 10 Billion CFU Capsule (2 doses), Culturelle 10 Billion CFU Capsule (4 doses)
- Where
- United States
- Volunteers
- 182 people
- Sponsor
- Medstar Health Research Institute
Anorexia Nervosa, Gut Microbiota
Effect of Treatment With Butyric Acid in Anorexia Nervosa
This clinical trial aims to evaluate the therapeutic potential of oral butyric acid supplementation in individuals with anorexia nervosa (AN).
- Conditions
- Anorexia Nervosa, Gut Microbiota, Weight Trajectory
- Trial name
- AN-BUTIX (NCT07289581)
- Testing
- Dietary Supplement: Butyric Acid
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Azienda Ospedaliero-Universitaria Careggi
Cardiogenic Shock
ExtraCorporeal Membrane Oxygenation in the Therapy of Cardiogenic Shock
Eligible patients with severe cardiogenic shock will be randomized to one of the two arms: immediate ECMO therapy or early conservative therapy.
- Trial name
- ECMO-CS (NCT02301819)
- Testing
- Veno-arterial extracorporeal membrane oxygenation (ECMO), Early conservative therapy according to standard practice
- Where
- 4 sites in Czechia
- Volunteers
- 122 people
- Sponsor
- Na Homolce Hospital
Halitosis
Photodynamic Therapy With Red Leds in Microorganisms Related to Halitosis
Halitosis is the term used to describe any unpleasant odor relative to expired air regardless of its source. The prevalence of halitosis in the population is approximately 30%, of which 80-90% of the cases originate in the oral…
- Trial name
- halitosis (NCT03656419)
- Testing
- photodynamic therapy, Tongue scraper
- Where
- Brazil
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Idiopathic Pulmonary Fibrosis, Chronic Obstructive Pulmonary Disease
Coping Strategies Within Pulmonary Rehabilitation in Patients With IPF and COPD
The aim of this prospective observational trial is to evaluate the influence of Coping strategies on pulmonary rehabilitation outcomes like 6-minute walk distance and Quality of life.
- Trial name
- NCT04257630
- Where
- Germany
- Volunteers
- 180 people
- Sponsor
- Schön Klinik Berchtesgadener Land
Agitation, Dementia
An Efficacy, and Safety Study Of BXCL501 For The Treatment Of Agitation Associated With Dementia
A randomized, double-blind, placebo-controlled parallel group 3-arm study assessing efficacy, safety, and tolerability of two doses BXCL501 in male and female geriatric residents (65 years and older) with acute agitation…
- Trial name
- NCT05276830
- Testing
- BXCL501
- Where
- 3 sites in United States
- Volunteers
- 5 people
- Sponsor
- BioXcel Therapeutics Inc
Pain
Ultrasound Guided Quadratus Lumborum Block for Postoperative Pain in Abdominoplasty
The original concept of a quadratus lumborum block (QLB) indicated for analgesia after abdominal surgery was first described by Blanco in 2007.
- Trial name
- NCT02932930
- Testing
- QLB bloc, 0.2% Ropivacaine, 0.9% normal saline
- Where
- Lebanon
- Volunteers
- 40 people
- Sponsor
- St Joseph University, Beirut, Lebanon
Anorexia Nervosa
The Experience of Affective Touch in Anorexia Nervosa
The aim of the present research will be to verify if the pleasantness of affective touch is comparable between women with AN and healthy women while measuring the level of social anhedonia and the lifespan experience of affective…
- Trial name
- AffTouch_AN (NCT05756530)
- Testing
- Affective touch paradigm
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Istituto Auxologico Italiano
Wrinkles, Scars
Pilot Evaluation of the Cynosure Potenza™ System for Treatment of Cosmetic Dermatologic Skin Conditions
The primary objective of this pilot study is exploratory investigation evaluating the Potenza microneedle fractional radiofrequency (RF) device and may be used in combination with the Icon intense pulsed light (IPL) device.
- Conditions
- Wrinkles, Scars, Stretch Marks, Pigmentation
- Trial name
- NCT05847530
- Testing
- Potenza, Icon
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Cynosure, Inc.
Low Back Pain
ED Physical Therapy for Chronic Low Back Pain
Emergency department (ED)-initiated physical therapy is a rapidly growing resource and represents a promising treatment approach to low back pain.
- Trial name
- NCT05206630
- Testing
- ED Physical Therapy
- Where
- United States
- Volunteers
- 128 people
- Sponsor
- Northwestern University
Neck Pain, Neck Pain Musculoskeletal
Proprioceptive Neuromuscular Facilitation And Passive Vertebral Mobilization For Neck Disability In Patients With Mechanical Neck Pain
Mechanical neck pain is a common musculoskeletal condition that affects many people, especially those with poor posture or repetitive neck movements.
- Conditions
- Neck Pain, Neck Pain Musculoskeletal, Mechanical Neck Pain, Proprioceptive Neuromuscular Facilitation
- Trial name
- NCT07042230
- Testing
- Proprioceptive Neuromuscular Facilitation (PNF), Passive Vertebral Mobilization (PVM)
- Where
- Pakistan
- Volunteers
- 62 people
- Sponsor
- University of Lahore
Carcinoid Syndrome
An Efficacy and Safety Study of Somatuline Depot (Lanreotide) Injection to Treat Carcinoid Syndrome
The purpose of this study was to determine whether monthly deep subcutaneous (s.c.) injections of lanreotide Autogel (Somatuline Depot) were effective and safe in controlling diarrhoea and flushing by reducing the usage of s.c.
- Trial name
- ELECT (NCT00774930)
- Testing
- Lanreotide
- Where
- 54 sites in United States, Brazil and 9 more
- Volunteers
- 115 people
- Sponsor
- Ipsen
Music Therapy
Effect of Music Therapy on Postoperative Health Outcomes
Patients underwent surgical procedure experiences acute postoperative pain, but less than half report adequate postoperative pain relief.
- Trial name
- MToPOHO (NCT04155528)
- Testing
- Music therapy
- Volunteers
- 60 people
- Sponsor
- Cairo University
Myocardial Infarction, ST Elevation Myocardial Infarction
Early Discharge Pathway Registry
Despite the year-on-year decrease, coronary artery disease (CAD) still remains one of the leading causes of mortality worldwide.
- Conditions
- Myocardial Infarction, ST Elevation Myocardial Infarction, Non-ST Elevation Myocardial Infarction
- Trial name
- NCT06040528
- Where
- 2 sites in United Kingdom
- Volunteers
- 20,000 people
- Sponsor
- Queen Mary University of London
Stroke, Cerebrovascular Accident
Non-invasive Brain Stimulation and Occupational Therapy To Enhance Stroke Recovery
The purpose of this study is to determine whether a non-painful, non-invasive, brain-stimulation technique called transcranial direct current stimulation (tDCS) combined with traditional physical-occupational therapy (OT) will…
- Conditions
- Stroke, Cerebrovascular Accident, CVA, Acute Stroke
- Trial name
- TDCS+OT (NCT00792428)
- Testing
- Real Transcranial Direct Current Stimulation
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Lung Diseases, Lung Diseases, Obstructive
Clinical Study of Intermittent Positive Pressure Breathing (IPPB)
To evaluate the efficacy of long-term intermittent positive pressure breathing (IPPB) treatment when used as an adjunct to the overall care of ambulatory outpatients with chronic obstructive pulmonary disease.
- Conditions
- Lung Diseases, Lung Diseases, Obstructive, Chronic Obstructive Pulmonary Disease
- Trial name
- NCT00000565
- Testing
- intermittent positive-pressure breathing
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Urinary Calculus
A Dose-finding Study of Silodosin in Patients With Urinary Calculi
The purpose of this study is to evaluate the efficacy and the safety of silodosin in urinary calculi patients.
- Trial name
- NCT01539265
- Testing
- silodosin
- Where
- Japan
- Volunteers
- 300 people
- Sponsor
- Kissei Pharmaceutical Co., Ltd.
Postoperative Pain, Lumbar Spine Surgery
Postoperative Pain Monitoring With ANI in Lumbar Spine Surgery
This study aims to compare two different pain management methods in patients undergoing elective lumbar spine surgery. Patients are randomly assigned to receive either an ultrasound-guided erector spinae plane block (ESPB) or…
- Trial name
- SPINE-ANI (NCT07455565)
- Testing
- Erector Spinae Plane Block, Intravenous Multimodal Analgesia
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Akdeniz University Hospital
Abscesses
Prospective Randomized Trial of Bactrim on 7 Day Outcome in Patients With Uncomplicated Abscesses
Patients will be enrolled in a multi-center study to prospectively evaluate outcome after treatment for an uncomplicated skin abscess. All patients will receive incision and drainage and wound cultures.
- Trial name
- NCT00973765
- Testing
- bactrim
- Where
- United States
- Volunteers
- 212 people, healthy volunteers welcome
- Sponsor
- 59th Medical Wing
Osteoarthritis
Efficacy of ThermoProfen in Patients With Mild to Moderate Pain Associated With Osteoarthritis of the Knee
ThermoProfen is a transdermal ketoprofen patch that is integrated with a long-lasting CHADD (Controlled Heat-Assisted Drug Delivery) unit for the treatment of chronic pain associated with osteoarthritis.
- Trial name
- NCT00488267
- Testing
- ThermoProfen™ (Matrix Transdermal Ketoprofen/CHADD™ System)
- Where
- 36 sites in United States
- Volunteers
- 679 people
- Sponsor
- ZARS Pharma Inc.
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