Clinical trials: Symptoms and Signs
Pain
Stimulating Catheter With or Without Ultrasound Guidance
To study whether the combination of ultrasound guidance and stimulating catheter could reduce the time for needle and catheter insertion compared with using stimulating catheter alone.
- Trial name
- NCT00980577
- Testing
- NUUS
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Peking University Third Hospital
Overweight and Obesity
Effect of Synbiotic 365 on Body Composition in Overweight and Obese Individuals
Evaluate the effect of Synbiotic 365 (Version 5 and 7) on body composition in overweight and obese individuals as measured by change in body mass index (BMI) and the percentage of body fat from Day 0 to Day 84 when compared to…
- Trial name
- Obesity (NCT04611477)
- Testing
- Rice Hulk, Synbiotic365 Ver 5, Synbiotic365 Ver 7
- Where
- India
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Vedic Lifesciences Pvt. Ltd.
Critical Illness
Precision Sedation in Intensive Care
Being critically ill and in need of mechanical ventilation is painful and distressing, and patients rarely have the capacity to communicate to express their needs.
- Trial name
- SENSE (NCT06991777)
- Testing
- Precision sedation in intensive care using neurophysiologic and respiratory targets.
- Where
- Norway
- Volunteers
- 100 people
- Sponsor
- Oslo University Hospital
Bronchopulmonary Dysplasia
Inhaled Budesonide for Non-ventilated Infants at High Risk of Bronchopulmonary Dysplasia: the i-BUD Pilot Study
Bronchopulmonary dysplasia (BPD) is one of the most important morbidities of preterm infants with a high incidence and significant impact on resource utilization and long-term outcome.
- Trial name
- NCT01895075
- Testing
- Inhaled budesonide, Normal saline
- Where
- Canada
- Sponsor
- Dr. Michael Dunn
Mechanical Low Back Pain
Mobile App-Supported Exercise Program For Mechanical Low Back Pain
Mechanical low back pain is one of the most common musculoskeletal disorders affecting daily activities and quality of life. Home exercise programs are frequently recommended in the management of low back pain; however, adherence…
- Trial name
- NCT07495475
- Testing
- Mobile Application-Supported Home Exercise Program, Printed Home Exercise Program
- Volunteers
- 50 people
- Sponsor
- Karabuk University
Colonic Polyps
Efficacy of Segmental Examination Twice of the Proximal Colon on Adenoma Detection
Segmental examination twice of the proximal colon might be helpful to increase adenoma detection rate (ADR).
- Trial name
- NCT02581475
- Testing
- Extending withdrawal time in the proximal colon, Segmental examination twice of the proximal colon
- Where
- China
- Volunteers
- 386 people, healthy volunteers welcome
- Sponsor
- Yanqing Li
Low Back Pain
Thera-Band® HEP for LBP Secondary Prevention
The purpose of this study is to determine the effectiveness of a Thera-Band based home exercise program (HEP) on LBP and disability 4 weeks post treatment discharge.
- Trial name
- TBKT_HEP (NCT02355275)
- Testing
- Home Exercise Program
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Sport and Spine Rehab Clinical Research Foundation
Prostate Cancer, Prostate Cancer Metastatic
Fecal Microbiota Transplant and Pembrolizumab for Men With Metastatic Castration Resistant Prostate Cancer.
All patients will be required to have a biopsy of a metastatic tumor deposit at study entry. Pembrolizumab will be administered at a dose of 200 mg as a 30 minute IV infusion every 3 weeks.
- Trial name
- NCT04116775
- Testing
- Fecal microbiota transplant, Pembrolizumab, Enzalutamide
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Julie Graff, MD
Safety and Efficacy
NKG2D CAR-NK Cell Therapy in Patients With Relapsed or Refractory Acute Myeloid Leukemia
This trial will explore the maximum tolerated dose of cord blood NKG2D CAR-NK in the treatment of recurrent refractory acute myeloid leukemia in a dose-escalation manner, and observe its clinical safety and efficacy.
- Trial name
- NCT05247957
- Testing
- CAR-NK cells
- Where
- China
- Volunteers
- 9 people
- Sponsor
- Hangzhou Cheetah Cell Therapeutics Co., Ltd
Cerebrovascular Accidents, Myocardial Infarction
Medical-economic Evaluation Comparing Intensive Outpatient Monitoring of Neuro-cardiovascular Diseases by Nurses, Doctors and Hospital and Private-sector Pharmacists, Compared to Usual Monitoring.
Cerebral Vascular Accidents (stroke) and Myocardial Infarction (MI), which share the same risk factors, treatments and pathophysiological mechanisms, have become two major public health problems due to the increase in their…
- Trial name
- DiVa (NCT04188457)
- Testing
- Usual follow-up, Intensive follow-up
- Where
- France
- Volunteers
- 859 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Acute Kidney Injury, Acute Kidney Injury Due to Sepsis
Use of NGAL for Fluid Dosing and CRRT Initiation in Pediatric and Neonatal AKI
This study will follow patients admitted to the PICU with sepsis, NICU with sepsis or after abdominal surgery, or CICU who are identified as being at risk for developing acute kidney injury.
- Conditions
- Acute Kidney Injury, Acute Kidney Injury Due to Sepsis, Neonatal Sepsis
- Trial name
- Taking Focus 2 (NCT05114057)
- Testing
- Renal Angina Index (RAI)
- Where
- United States
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Snoring
Investigating Reaction Time Among Children Who Snore
The investigators feel that children who have OSA or sleep-disordered breathing may have a different reaction time than normal variants. Children who have OSA are known to have behavioral and sleep patterns that are different.
- Trial name
- NCT02053012
- Testing
- PVT-192
- Where
- United States
- Volunteers
- 93 people
- Sponsor
- Vidya Raman
Obesity, Weight Loss
Auricular Acupressure Integrated With Mobile Device for Weight Reduction
Obesity is a common global health problem. A three-arm randomised waitlist-controlled feasibility trial is proposed. A total of 59 subjects (19-21 subjects per arm) will be recruited.
- Conditions
- Obesity, Weight Loss, Mobile Application, Ear Acupressure
- Trial name
- NCT03442712
- Testing
- Auricular acupressure plus smartphone App, Auricular acupressure
- Where
- Hong Kong
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Obesity, Abdominal
Electroacupuncture Combined With Umbilical Moxibustion on Abdominal Obesity of Yang Deficiency
Obesity is a chronic metabolic disease that seriously harms human health, while abdominal obesity is more closely related to diseases such as type 2 diabetes, cardiovascular disease, and tumors, and has a higher risk.
- Trial name
- NCT04835181
- Testing
- Electroacupuncture combined with umbilical moxibustion, Electroacupuncture
- Volunteers
- 68 people
- Sponsor
- Hubei Hospital of Traditional Chinese Medicine
Obesity
Effect of Intranasal Insulin on Cognitive Processes and Appetite
This study investigates the effect of intranasal insulin on cognitive processes (behavioural and neural) in healthy lean and obese female adults.
- Trial name
- NCT03632681
- Testing
- Intranasal Insulin
- Where
- United Kingdom
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Birmingham
Kidney Stone
Comparing Pneumatic Versus Ultra-sonic Percutaneous Nephrolithotomy in Large Kidney Stones
The purpose of this study is to determine which type of percutaneous nephrolithotomy is better in large kidney stones
- Trial name
- NCT02751281
- Testing
- Pneumatic percutaneous nephrolithotomy, Ultra-sonic percutaneous nephrolithotomy
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Isfahan University of Medical Sciences
Heart Failure, Coronary Disease
Chronic Heart Failure Analysis and Registry in the Tohoku District 2 (CHART-2 Study)
Chronic Heart Failure Analysis and Registry in the Tohoku District 2 (CHART-2 Study) is a large, prospective, hospital-based cohort study to investigate the following: Characteristics of patients with chronic heart failure and…
- Conditions
- Heart Failure, Coronary Disease, Heart Valve Diseases, Cardiomyopathies
- Trial name
- NCT00418041
- Where
- Japan
- Volunteers
- 10,000 people
- Sponsor
- Hiroaki Shimokawa, MD, PhD
Acute Decompensated Heart Failure; Renal Dysfunction
Safety and Efficacy Study to Evaluate the Effect of SLV320 on Renal Function in Patients With Worsening Heart Failure
The purpose of this study is to determine the efficacy and safety of IV SLV320 in acute heart failure patients with renal dysfunction.
- Trial name
- NCT00744341
- Testing
- SLV320
- Where
- 105 sites in United States, Canada and 9 more
- Volunteers
- 46 people
- Sponsor
- Solvay Pharmaceuticals
Adolescent Obesity
The Effect of Time-Restricted Feeding on Body Composition and Some Metabolic Parameters in Obese Adolescents
Obesity is now recognized as a serious public health problem. It is known that obesity seen in adolescence is largely carried over to adulthood.
- Trial name
- NCT06616454
- Testing
- Intervention group - Time restricted feeding
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Sümeyra Başar
Diffuse Large B-cell Lymphoma
Treatment Resistance Related With Gene Expression Profile of Diffuse Large B-cell Lymphoma
The investigators perform a retrospective microarray gene expression profiling study of FFPE from a cohort of DLBCL patients with whole genome cDNA mediated Annealing Selection and Ligation (WG-DASL) assay.
- Trial name
- NCT01606605
- Where
- South Korea
- Volunteers
- 350 people
- Sponsor
- Samsung Medical Center
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