Clinical trials: Symptoms of Depression
Depression, Anxiety
Latent Structure of Multi-level Assessments and Predictors of Outcomes for Women in Recovery
In this study the investigators will seek to improve their understanding of how positive and negative valence systems, cognition, and arousal/interoception are inter-related in disorders of trauma, mood, substance use, and eating…
- Conditions
- Depression, Anxiety, Eating Disorders, Drug Use Disorders
- Trial name
- NCT02601495
- Testing
- Women in a court diversion program
- Volunteers
- 100 people
- Sponsor
- Laureate Institute for Brain Research, Inc.
Hypoactive Sexual Desire Disorder, Female Sexual Arousal Disorder
Effects of Early Abuse on Adult Intimate Relationships
This study is designed to help us better understand the factors that affect the sexual lives of women who have been sexually mistreated during childhood.
- Conditions
- Hypoactive Sexual Desire Disorder, Female Sexual Arousal Disorder, Female Orgasmic Disorder, Major Depressive Disorder
- Trial name
- NCT01803802
- Testing
- Expressive writing
- Where
- United States
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Bipolar Depression Depressed Phase, Obesity & Overweight
The Effects of Lumateperone on Obesity and Physiologic Aging and Their Association With Antidepressant Response in Bipolar Depression
This research study examines how a medication called lumateperone may affect mood symptoms, and inflammation in adults with bipolar disorder over approximately 6 weeks.
- Trial name
- NCT07699445
- Testing
- Lumateperone 42 mg
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Massachusetts General Hospital
Parkinson Disease
The Impact of Three Distinct Exercise Types on Fatigue, Anxiety, and Depression in Parkinson's Disease
The purpose of the study is to learn about the impact of exercise on fatigue, anxiety, and depression in Parkinson's disease. It is well established that exercise improves the motor symptoms of Parkinson's disease.
- Trial name
- PDExercise (NCT03833349)
- Testing
- Spinning Class, Yoga Class, Dance Class
- Where
- 2 sites in United States
- Volunteers
- 24 people
- Sponsor
- Premier Health
Fibromyalgia, Anxiety
The Relationship Between Diaphragm Muscle Thickness and Fibromyalgia
Fibromyalgia syndrome is characterized by chronic pain, fatigue, sleep problems and functional symptoms. Fatigue, anxiety and depression disorders, poor quality of life, sleep disorders, decreased concentration, and impaired…
- Conditions
- Fibromyalgia, Anxiety, Depression, Diaphragm Issues
- Trial name
- NCT06396949
- Testing
- Fibromyalgia study form, Pulmonary function test, Ultrasonographic Diaphragm Thickness Measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Mental Health Issue, Depression
Clinical Investigation of Syndi
Mental health concerns are a growing global concern, but support can still be difficult to access. Digital health technologies can help people access support, but with over 10,000 mental health apps available, it can be difficult…
- Conditions
- Mental Health Issue, Depression, Anxiety
- Trial name
- NCT06451549
- Testing
- Syndi recommender system for mental health apps
- Where
- 4 sites in United Kingdom
- Sponsor
- Newcastle University
Tinnitus, Hearing Loss
Correlation Analysis of Hearing Thresholds, Validated Questionnaires and Psychoacoustic Measurements in Tinnitus Patients
Objective: To evaluate the correlation between audiometric thresholds, pitch matching (PM), minimum masking level (MML), Tinnitus Handicap Inventory (THI) and the Beck Depression Inventory (BDI) in tinnitus patients.
- Conditions
- Tinnitus, Hearing Loss, Depression
- Trial name
- NCT00976547
- Where
- 2 sites in Brazil
- Volunteers
- 48 people
- Sponsor
- Faculdade de Medicina de Valenca
Healthy
A Study to Evaluate the Pharmacokinetics of Duloxetine in Chinese Han Healthy Subjects
The primary objective of this study is to evaluate the pharmacokinetics of duloxetine hydrochloride tablets in Chinese Han Healthy Subjects.
- Trial name
- NCT00933452
- Testing
- duloxetine
- Where
- China
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
Depression
Behavioral Activation With Depressed Adolescents
Twenty percent of adolescents will have at least one episode of clinical depression by age 18, and 65% will experience transient or less severe depressive symptoms.
- Trial name
- NCT01137149
- Testing
- Behavioral Activation Therapy, Treatment as Usual- Psychotherapy
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Seattle Children's Hospital
Insomnia, Depression
The Sleep Course: An Online Sleep Intervention for Adults With Self-reported Sleep Difficulties
This study evaluates an internet-delivered cognitive behavioural therapy for insomnia (ICBTi) intervention, known as the Sleep Course, within a routine online therapy clinic (the Online Therapy Unit).
- Conditions
- Insomnia, Depression, Anxiety
- Trial name
- NCT06745349
- Testing
- Sleep Course
- Where
- Canada
- Volunteers
- 56 people
- Sponsor
- University of Regina
Depression, Major Depressive Disorder
Patient Dimensions as Predictors of Varied Treatment Responses and Outcomes in Patients With Major Depression
Depression affects over one million people in Canada, resulting in $14.4 billion per year in costs to Canadian society. In order to prevent this often lifelong disorder, it is critically important to identify risk factors for the…
- Trial name
- NCT00744406
- Testing
- Cognitive Behavioral Therapy, Interpersonal Therapy, Antidepressant medication (sertraline ,paroxetineor or venlafaxine)
- Where
- Canada
- Volunteers
- 72 people
- Sponsor
- Centre for Addiction and Mental Health
Emotional Disorders, Anxiety
Blended Unified Protocol for Emotional Disorders in Primary Care
The goal of this clinical trial is to learn if a "blended" therapy format (combining face-to-face therapy sessions with a smartphone app) works to treat emotional disorders, such as depression and anxiety, in adults.
- Conditions
- Emotional Disorders, Anxiety, Depression
- Trial name
- NCT07432906
- Testing
- Unified Protocol
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Aydin Adnan Menderes University
Depression, Acute Ischemic Stroke
Prophylactic Effects of Agomelatine for Poststroke Depression
The incidence of depression in stroke patients with frontal lobe involvement was reported to be as high as 42%. Agomelatin, a type 1/2 melatonin receptor agonist and serotonin 2C receptor antagonist, is effective in treatment of…
- Trial name
- PRAISED (NCT05426304)
- Testing
- Agomelatine
- Volunteers
- 420 people
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
Obsessive Compulsive Disorder (OCD)
Gamified Combined Cognitive Bias Modification in Adults Diagnosed With OCD: Randomized Controlled Trial
This randomized controlled trial examines the effects of a mobile-based gamified combined cognitive bias modification (CBM-C) intervention on obsessive-compulsive symptoms, obsessive beliefs, attentional and interpretation…
- Trial name
- NCT06941155
- Testing
- Gamified-Combined Cognitive Bias Modification, Standard Combined Cognitive Bias Modification
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Dokuz Eylul University
Cognitive/Functional Effects, Depression
Physical and Mental Assessment of Older Patients With Newly Diagnosed Acute Myeloid Leukemia
RATIONALE: Learning about physical ability and mental function over time in older patients with acute myeloid leukemia may help doctors learn about the long-term effects of treatment and plan the best treatment.
- Conditions
- Cognitive/Functional Effects, Depression, Leukemia
- Trial name
- NCT00499785
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Wake Forest University Health Sciences
Pacing-Induced Cardiomyopathy
Effect of Right Ventricle Lead Position on The Psychological Aspects of Patients With A Dual Chamber Pacemaker
The purpose of the current study was to determine the factors associated with increased levels of anxiety and depression both before and after pacemaker implantation and examine if changes in these symptoms occur during the first…
- Trial name
- NCT06008340
- Testing
- Dual chamber Pacemaker
- Where
- Egypt
- Volunteers
- 182 people
- Sponsor
- Kafrelsheikh University
Major Depressive Disorder With Psychotic Features
Seroquel Alone Versus Seroquel With an SSRI for Depression With Psychotic Symptoms
The purpose of this study is to compare the efficacy and tolerability of Seroquel monotherapy for the treatment of Major Depression with Psychotic features with Seroquel plus Selective Serotonin Reuptake Inhibitor.
- Trial name
- Seroquel (NCT00955474)
- Testing
- Quetiapine, escitalopram, Sertraline
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Massachusetts General Hospital
Intervertebral Disc Displacement, Lumbar Disc Herniation
The Effect of Manual Therapy on Psychological Factors and Quality of Life in Lumbal Disc Herniation Patients
When the literature is examined, there are studies examining the relationship between low back pain and anxiety depression, quality of life and LDH in patients with lumbar disc herniation.
- Conditions
- Intervertebral Disc Displacement, Lumbar Disc Herniation, Psychological, Quality of Life
- Trial name
- NCT05804357
- Testing
- Manual Therapy, Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Muş Alparslan University
Depression, Depressive Disorder
Follow-up Study With Clinical Vitamin D Supplementation Trial on Patients With Depression (DepFuD)
Depression affects 350 million people worldwide. In the light of the global disease burden statistics, the efficacy of current treatments for depression appears insufficient.
- Trial name
- DepFuD (NCT02521012)
- Testing
- Vitamin D 10 micrograms, Vitamin D 100 micrograms
- Where
- Finland
- Volunteers
- 319 people
- Sponsor
- Kuopio University Hospital
Depression, Anxiety
The EARN-Health Trial of Financial Savings and Health
The current literature in social epidemiology and public health suggests that low financial savings has an unsurprising negative relationship with subjective well-being, and increases the odds of making visits to a healthcare…
- Conditions
- Depression, Anxiety, Alcohol Abuse, Tobacco Abuse
- Trial name
- EARN-Health (NCT02185612)
- Testing
- Savings program
- Where
- United States
- Volunteers
- 678 people, healthy volunteers welcome
- Sponsor
- Stanford University