Clinical trials: System Validation
Breast Cancer
Case Collection Study for Collecting Images for the Development and Validation of Computer Aided Detection Software
The study objective is to assess the performance of the MammoDetector Pro to correctly mark biopsy-proven breast cancers imaged on the Siemens Mammomat Novation FFDM system compared to conventional film-screen mammography.
- Trial name
- NCT00756834
- Testing
- Screening
- Where
- United States
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Siemens Medical Solutions
REM Sleep Behavior Disorder
French Validation of a Severity Scale in REM Sleep Behavior Disorder (SEV-TCSP)
REM (Rapid Eye Movements) Sleep Behavior Disorder (RBD) is a parasomnia characterized by episodes of elaborate or violent motor activity during dreams, which can lead to injury and sleep disruption in patient and / or his/her…
- Trial name
- SEV-TCSP (NCT04071899)
- Testing
- Scale vaidation
- Where
- 5 sites in France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Multiple Myeloma (MM)
Validating DW-MRI and Fat Fraction in Multiple Myeloma Post-ASCT: The RAC-FAT Study"
This is a multicenter, observational, retrospective-prospective study designed to validate the predictive role of advanced imaging in patients with newly diagnosed multiple myeloma (NDMM).
- Trial name
- NCT07746232
- Testing
- DW-MRI (MY-RADS/RAC score), Fat Fraction (rFF%), Clinical Data Collection
- Where
- 10 sites in Italy
- Volunteers
- 92 people
- Sponsor
- Fondazione EMN Italy Onlus
Knee Osteoarthritis
Navigation System for in Vivo Measurement of the Kinematics of the Knee
The knee prosthesis is a validated treatment for end-stage osteoarthritis, and this intervention usually provides a significant improvement in the quality of life of patients.
- Trial name
- NCT02467699
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Strasbourg, France
Pain, Acute
Validation of the Polish Version of BPS (POL-BPS).
Between 40 to 70% of patients with critical illness experience moderate to severe pain. Diagnosing pain and assessing its severity is difficult in non-verbal patients both in an Intensive Care Unit and in Postoperative Unit after…
- Trial name
- POL-BPS (NCT03127306)
- Testing
- Assessment of Polish version of BPS
- Where
- Poland
- Volunteers
- 59 people
- Sponsor
- Pomeranian Medical University Szczecin
Presbyopia, Low Vision
Development and Validation of a Digital Optotype for Near Vision in Greek Language.
Primary objective of our study is to develop and validate a computer-based digital near-vision optotype based on the Greek version of the print MNREAD.
- Conditions
- Presbyopia, Low Vision, Near Vision
- Trial name
- DeDART (NCT04242836)
- Testing
- MNREAD testing
- Where
- Greece
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Democritus University of Thrace
Parkinson's Disease (PD), Functional Capacity
Validity and Reliability of the Six-Minute Pegboard Ring Test in Individuals With Parkinson's Disease
Parkinson's patients who volunteer to participate in the study will be included. Parkinson's patients participating in the study will be referred from the SANKO University Hospital Neurology Outpatient Clinic.
- Conditions
- Parkinson's Disease (PD), Functional Capacity, Upper Extremity Function, Validity and Safety
- Trial name
- NCT07422064
- Where
- Turkey (Türkiye)
- Volunteers
- 47 people
- Sponsor
- Sanko University
Trisomy 21
Non Invasive Prenatal Diagnosis of Trisomy 21 by Genetic Analysis of Circulating Fetal Cells
The objective of this project is to develop a non-invasive prenatal diagnostic test for trisomy 21 which is reliable, sensitive and cost-effective, and thus, offers an alternative to the currently employed invasive diagnostic…
- Trial name
- ISETTRI21 (NCT01725438)
- Testing
- sample blood
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Cerebral Palsy, Visual Impairment
Turkish Validity and Reliability of the Visual Function Classification System (VFCS)
Cerebral Palsy (CP) is the most common childhood disorder that occurs with a lesion in the developing infant brain, seen in 2-3/1000 live births.
- Conditions
- Cerebral Palsy, Visual Impairment, Visual Disorder, Cerebral Visual Impairment
- Trial name
- NCT05102955
- Testing
- Observational questionnaires
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Kahramanmaras Sutcu Imam University
Epilepsy
Attention-Deficit Hyperactivity Disorder (ADHD) Rating Scale and Epilepsy
The cognitive and psychiatric comorbidities are crucial endpoints in epileptic patients. Among these comorbidities, the Attention-Deficit Hyperactivity Disorder (ADHD) accounts for one of the most important in terms of frequency…
- Trial name
- NCT01482026
- Testing
- ADHD Rating Scale-IV
- Where
- 15 sites in France
- Volunteers
- 173 people
- Sponsor
- Hospices Civils de Lyon
Obstructive Sleep Apnea (OSA)
Validity of a Home Respiratory Polygraphy for the Diagnosis of Obstructive Sleep Apnea
To assess the diagnostic validity and cost-effectiveness of a APNiA device, a home respiratory polygraphy (HRP).
- Trial name
- APNiA (NCT03415633)
- Testing
- Home Respiratory Polygraphy (APNIA), Standard Polysomnography (PSG)
- Where
- Spain
- Volunteers
- 251 people
- Sponsor
- Hospital Universitario Araba
Parkinson Disease, Multiple Sclerosis
Turkish Version of Mini-BESTest, Validity and Reliability for Adult Participants With Sensoriomotor Impairments
The aim of this study is to present the Turkish version of miniBESTest which evaluates the reasons of balance deficit and postural control.
- Conditions
- Parkinson Disease, Multiple Sclerosis, Trauma, Brain
- Trial name
- NCT03839381
- Volunteers
- 50 people
- Sponsor
- Ordu University
Hearing Impaired
Effects of Stimulus Validity on Speech Recognition
The effects of talker variability will be investigated with four groups of listeners (young normal-hearing; old normal-hearing; young hearing-impaired; old hearing-impaired).
- Trial name
- NCT00013364
- Testing
- Talker variability
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- US Department of Veterans Affairs
Cleansing Quality of the Colon
Artificial Intelligence and Bowel Cleansing Quality
The main purpose of the study is to design and validate a convolutional neural network (CNN) with the ability to discriminate between pictures of effluents with different qualities of bowel cleansing and in a second time to…
- Trial name
- CALPER2 (NCT05553977)
- Testing
- Bowel preparation for colonoscopy, Colonoscopy
- Where
- Spain
- Volunteers
- 667 people
- Sponsor
- Hospital Universitario de Canarias
Delirium
Enhancing European Management of Analgesia, Sedation and Delirium
This prospective, multicenter study aims to evaluate the effect of routine training of intensive care unit (ICU) staff on the implementation rate of screening tools for pain, agitation and delirium (PAD) ) in three one day…
- Trial name
- NCT03553719
- Where
- Germany
- Volunteers
- 430 people
- Sponsor
- Charite University, Berlin, Germany
Obstructive Sleep Apnea
Validation of a Simplified MATRx Plus
Sleep apnea (OSA) is a condition in which the air passage in the throat closes or partly closes during sleep and repeatedly interrupts breathing.
- Trial name
- NCT03812692
- Testing
- MATRx plus
- Where
- Canada
- Volunteers
- 59 people
- Sponsor
- Zephyr Sleep Technologies
Chronic Urticaria
Validation of an Urticaria Control Test
The aim of this study is to validate a previously developed patient reported outcome instrument (in project UCT-D) to assess disease control in chronic urticaria patients (Urticaria Control Test - UCT) of age 12 and older.
- Trial name
- UCT-V (NCT01614834)
- Where
- 2 sites in Germany
- Volunteers
- 120 people
- Sponsor
- Charite University, Berlin, Germany
Colorectal Cancer
Development and Validation of Metabolic Biomarkers for Early Diagnosis, Prognosis, and Recurrence of Colorectal Cancer：MetBio-CRC
This prospective clinical observational study aims to construct a metabolite database specifically for colorectal cancer patients using metabolomics technology.
- Trial name
- NCT07068529
- Where
- China
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Shanghai Minimally Invasive Surgery Center
Rett Syndrome
Validating Innovative Biosensors for Rett Autonomic Symptom Tracking
The VIBRANT study aims to validate biosensors to objectively and directly measure symptoms in Rett syndrome and create confidence in the use of these devices in clinical trials.
- Trial name
- VIBRANT (NCT06338267)
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Rett Syndrome Research Trust
Obstructive Sleep Apnea
Validation and Reproducibility of the Six-minute Step Test in Individuals With Obstructive Sleep Apnea Treated With CPAP
Introduction: The Obstructive Sleep Apnea (OSA) is characterized by obstructed superior airway during sleeping period promoting intermittent hypoxia-reoxygenation events.
- Trial name
- NCT03334331
- Testing
- Six-minute step test, Six-minute walk test
- Where
- Brazil
- Volunteers
- 48 people
- Sponsor
- Universidade Federal de Pernambuco