Clinical trials: System Validation, open to volunteers
Breakthrough Pain, Palliative Medicine
Paediatric Breakthrough Pain Assessment
Many children and young people with life-limiting and life-threatening illnesses get sudden bursts of pain called breakthrough pain. At the moment, there aren't any good ways to measure this pain in children and young people.
- Conditions
- Breakthrough Pain, Palliative Medicine, Oncology Pain, Pediatric ALL
- Trial name
- BEACON (NCT06790719)
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- University of Southampton
Obstructive Sleep Apnea
CES-EES Clinical Score and a Wearable Ring Sensor for Obstructive Sleep Apnea: Individual and Combined Validation Against In-Laboratory Polysomnography
This study evaluates whether a clinical upper airway assessment tool (the Clinical Examination Score plus ENT Examination Score, CES-EES) and an artificial-intelligence wearable ring (Belun Ring, Belun Sleep System BLS-100) can…
- Trial name
- NCT07785999
- Testing
- Belun Ring (Belun Sleep System BLS-100), CES-EES Clinical Scoring
- Where
- Malaysia
- Volunteers
- 58 people
- Sponsor
- University of Malaya
Stroke
Clinical Validation of an Instrumented Glove for Sensorimotor Rehabilitation
The goal of this clinical trial is to evaluate the DESC-Glove, an instrumented glove developed for sensorimotor rehabilitation in individuals recovering from a stroke, utilizing non-invasive vibrational feedback.
- Trial name
- NCT06649968
- Testing
- DESC-Glove (active), Traditional rehabilitation
- Where
- 6 sites in Italy
- Volunteers
- 47 people
- Sponsor
- Christian Cipriani
Gastric Cancer
Development and Validation of Metabolic Biomarkers for Early Diagnosis, Prognosis, and Recurrence of Gastric Cancer：MetBio-GC
This prospective clinical observational study aims to construct a metabolite database specifically for gastric cancer patients using metabolomics technology.
- Trial name
- NCT07076979
- Where
- China
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Shanghai Minimally Invasive Surgery Center
Cancer Screening, Oral Cancer
Application and Validation of a Smartphone-based Deep Learning System for Oral Potentially Malignant Disorders and Oral Cancer Screening
The goal of this clinical trial is to learn if smartphone-based deep learning system works to accurately detect oral potentially malignant disorders and oral cancer in adults.
- Conditions
- Cancer Screening, Oral Cancer, Oral Potentially Malignant Disorders
- Trial name
- NCT06862414
- Testing
- Smartphone-based deep learning system
- Where
- Taiwan
- Volunteers
- 954 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Multiple Myeloma (MM)
Validating DW-MRI and Fat Fraction in Multiple Myeloma Post-ASCT: The RAC-FAT Study"
This is a multicenter, observational, retrospective-prospective study designed to validate the predictive role of advanced imaging in patients with newly diagnosed multiple myeloma (NDMM).
- Trial name
- NCT07746232
- Testing
- DW-MRI (MY-RADS/RAC score), Fat Fraction (rFF%), Clinical Data Collection
- Where
- 10 sites in Italy
- Volunteers
- 92 people
- Sponsor
- Fondazione EMN Italy Onlus
Colorectal Cancer
Development and Validation of Metabolic Biomarkers for Early Diagnosis, Prognosis, and Recurrence of Colorectal Cancer：MetBio-CRC
This prospective clinical observational study aims to construct a metabolite database specifically for colorectal cancer patients using metabolomics technology.
- Trial name
- NCT07068529
- Where
- China
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Shanghai Minimally Invasive Surgery Center
Stroke
Clinical Validation of an Artificial Intelligence-Based G-FAST Score in Patients With Stroke
This study aims to validate the clinical performance of an artificial intelligence (AI)-based automatic assessment system for the G-FAST score.
- Trial name
- NCT07538492
- Volunteers
- 297 people
- Sponsor
- Xuanwu Hospital, Beijing
Stroke, Hypertonia
Validity and Reliability of the Hypertonia Assessment Tool (HAT) in Stroke Patients
In this study, the validity and reliability of the Hypertonia Assessment Tool (HAT), which has previously been validated in the pediatric cerebral palsy (CP) population, will be evaluated in adult individuals who have experienced…
- Conditions
- Stroke, Hypertonia, Dystonia, Rigidity
- Trial name
- NCT07429383
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Traumatic Brain Injuries
Validation and Standardisation of a "Neuralix" Digital Ecological Battery
The management of head trauma patients requires the assessment of cognitive disorders using standardized neuropsychological tests and questionnaires.
- Trial name
- VANOLIX (NCT06830291)
- Where
- France
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Direction Centrale du Service de Santé des Armées
Type 2 Diabetes Mellitus (T2DM), Cardiovascular Diseases
Cardioprotective Effects of SGLT2 Inhibitors and GLP-1 Receptor Agonists in Korean Patients With Type 2 Diabetes
This observational study will evaluate the cardiovascular effects of sodium-glucose cotransporter-2 inhibitors (SGLT2 inhibitors) and glucagon-like peptide-1 receptor agonists (GLP-1 receptor agonists) in Korean adults with type…
- Conditions
- Type 2 Diabetes Mellitus (T2DM), Cardiovascular Diseases, Stage B Heart Failure
- Trial name
- NCT07770737
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Dongtan Sacred Heart Hospital
Quality of Life (QOL), Patient-Reported Outcome Measures (PROMs)
Validation of the EQ-5D-Y-3L and EQ-5D-Y-5L for Paediatric Patients in China
The goal of this observational study is to validate the EQ-5D-Y-3L and EQ-5D-Y-5L in measuring health-related quality of life (HRQoL) for paediatric patients with different health conditions in China.
- Conditions
- Quality of Life (QOL), Patient-Reported Outcome Measures (PROMs), Pneumonia Childhood, Neuroblastoma (NB)
- Trial name
- NCT06873672
- Where
- China
- Volunteers
- 360 people
- Sponsor
- RenJi Hospital
Juvenile Idiopathic Arthritis, Childhood Rheumatic Disease
Dynamic Gait Index as a Functional Gait Assessment Measure in Children With JIA
Juvenile idiopathic arthritis (JIA) is one of the most common chronic rheumatic diseases seen in childhood. Pain, joint swelling and loss of function caused by inflammation significantly reduce the patients' quality of life and…
- Trial name
- NCT06870045
- Testing
- Physical examination, Dynamic Gait Index
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Active Aging Individuals Aged 65 and Over, Aging
Italian Validation of the dNA Scale and Its Correlation With Neurocognitive Variables
The goal of this experimental multicentric intervention study is to validate, in Italian, the dynamic Neurocognitive Adaptation (dNA) Scale, which has already been validated in English, among a healthy elderly population (aged 65…
- Conditions
- Active Aging Individuals Aged 65 and Over, Aging, Mild Cognitive Impairment (MCI), Dementia
- Trial name
- NCT07533084
- Where
- 8 sites in Italy
- Volunteers
- 265 people, healthy volunteers welcome
- Sponsor
- Neuromed IRCCS
Rheumatoid Arthritis (RA, 6 Minutes Stepper Test
An Alternative Assessment in Patients with Rheumatoid Arthritis: 6 Minute Step Test
Although joint involvement is predominant, RA is a systemic disease that can affect many organs. RA is a disease that includes changes such as inflammation, joint pain, fatigue, increased risk of coronary and heart disease.
- Trial name
- NCT06838884
- Testing
- 6 minutes step test and bicycle ergometer
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Firat University
Superficial Esophageal, Gastric or Colorectal Lesions
Validation of AI-ENDO System in Endoscopic Submucosal Dissection
This study is a pilot trial designed to evaluate the feasibility and safety of Al-ENDO assisted ESD in patients with gastrointestinal superficial lesions.
- Trial name
- NCT07392268
- Testing
- AI-ENDO system, Conventional ESD
- Where
- Hong Kong
- Volunteers
- 60 people
- Sponsor
- Chinese University of Hong Kong
Acute Brain Injury Coma, Neurocritical Care
Development and Validation of a Prognostic Model for Neurocritical Patients Using Multimodal Brain Monitoring
This study aims to develop and validate a prognostic model for neurocritical patients using multimodal brain monitoring data. By combining data from various monitoring techniques such as EEG, TCD, and NIRS, this model will help…
- Conditions
- Acute Brain Injury Coma, Neurocritical Care, Cerebral Infarction, Intracranial Hemorrhages
- Trial name
- NCT07115459
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Xiangya Hospital of Central South University
Ovarian Neoplasms
Validation of the Sentinel Lymph Node Technique in Early-stage Ovarian Cancer (SENTOV II)
This clinical trial investigates the sentinel lymph node (SLN) technique as a less invasive alternative to conventional lymphadenectomy in patients with early-stage ovarian cancer.
- Trial name
- SENTOV II (NCT06963268)
- Testing
- Sentinel Node Technique
- Where
- Spain
- Volunteers
- 200 people
- Sponsor
- Instituto de Investigacion Sanitaria La Fe
Juvenile Idiopathic Arthritis (JIA)
Reliability and Validity of the Glittre Activities of Daily Living Test in Children and Adolescents With Juvenile Idiopathic Arthritis
Juvenile Idiopathic Arthritis (JIA) is children's most common inflammatory rheumatic disease. The International League of Associations for Rheumatology (ILAR) defines it as a chronic arthritis condition that begins before the age…
- Trial name
- NCT06806774
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Hacettepe University
TBI, TBI Traumatic Brain Injury
fREMS for Mortality Prediction in TBI
This prospective observational study aims to develop and internally validate a new clinical score, the FOUR-Rapid Emergency Medicine Score (fREMS), for predicting in-hospital mortality in patients with traumatic brain injury…
- Trial name
- fREMS (NCT07816016)
- Where
- Iraq
- Volunteers
- 2,000 people
- Sponsor
- Al-Nahrain University