Clinical trials: Systemic Immune-inflammation Index
Temporomandibular Disorders (TMD), Pregnancy
Evaluation of Temporomandibular Disorders During Pregnancy
This study aims to evaluate how temporomandibular disorders (TMD) - a condition affecting the jaw joint and chewing muscles - change during pregnancy.
- Trial name
- NCT07791173
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Zeynep Serra Kalkan
Ankylosing Spondylitis
The Relationship Between Systemic Immune Inflammation Index and Disease Activity in Patients With Ankylosing Spondylitis
In this study, the aim was to investigate the relationship between SII and other laboratory parameters with disease activity in AS patients and to discuss its usability in the follow-up and treatment process.
- Trial name
- NCT06094673
- Testing
- No intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Istanbul Physical Medicine Rehabilitation Training and Research Hospital
Crush Syndrome, Rhabdomyolysis
Inflammation Indıces and Mortality in Adult Crush Syndrome
This single-center, retrospective observational cohort study evaluated the prognostic value of complete blood count-derived inflammatory indices - the neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR)…
- Conditions
- Crush Syndrome, Rhabdomyolysis, Systemic Inflammatory Response, Critical Illness
- Trial name
- NCT07433127
- Where
- Turkey (Türkiye)
- Volunteers
- 325 people
- Sponsor
- Ataturk University
Acute Kidney Injury, Cardiac Surgery
Prediction of Acute Kidney Injury After Cardiac Surgery With Cardiopulmonary Bypass
Acute kidney injury (AKI) is a common and serious complication following cardiac surgery performed under cardiopulmonary bypass and is associated with increased morbidity, mortality, and prolonged hospital stay.
- Conditions
- Acute Kidney Injury, Cardiac Surgery, Cardiopulmonary Bypass Surgery, Cardiac Surgery Associated - Acute Kidney Injury
- Trial name
- AKI-CPB (NCT07343830)
- Where
- Turkey (Türkiye)
- Volunteers
- 455 people
- Sponsor
- Ataturk University
Obesity (BMI > 35), Morbid Obesity
Predictive Value of Nutritional and Inflammatory Indices for Postoperative Complications After Bariatric Surgery
Bariatric surgery is an effective treatment for severe obesity, but postoperative complications remain an important cause of morbidity.
- Trial name
- BARI-NUTRI (NCT07747168)
- Testing
- Bariatric Surgery
- Where
- Greece
- Volunteers
- 600 people
- Sponsor
- G.Gennimatas General Hospital
Osteoporosis, Postmenopausal, Osteoporotic Fractures
Evaluation of the Prognostic Role of the Systemic Immune Inflammation Index in Postmenopausal Osteoporosis
This study is a retrospective case-control study. In the study, the data of 304 patients who were evaluated in our clinic between January 2017 and January 2020 with a pre-diagnosis or diagnosis of postmenopausal osteoporosis were…
- Trial name
- NCT04748029
- Testing
- Systemic immune inflammation index
- Where
- Turkey (Türkiye)
- Volunteers
- 139 people
- Sponsor
- Ufuk University
Pancreatic Cancer
SII And PALBI is Associated With the Prognosis of Pancreatic Cancer Surgery(SII,PALBI)
Chronic inflammation and immune dysfunction play a key role in the development of tumors. The aim of the study is to investigate the predictive value of SII and PALBI grade for the patients with pancreatic cancer surgery.
- Trial name
- SII (NCT05012540)
- Volunteers
- 214 people
- Sponsor
- The Affiliated Hospital of Qingdao University
Myocard Infarctus
New Predictors in Determining the Need for Invasive Treatment in Non-STEMI
Non-ST elevation acute coronary syndrome (NSTE-ACS) is a heterogeneous disease with a wide range of treatment options from the medical follow-up to early invasive treatment due to complete occlusion of the culprit artery.
- Trial name
- non-STEMI (NCT04763213)
- Testing
- Coronary Angiography
- Where
- Turkey (Türkiye)
- Volunteers
- 276 people
- Sponsor
- Kahramanmaras Sutcu Imam University
Systemic Immune-inflammatory Index, Erector Spinae Plane Block
Impact of Erector Spinae Plane Block on Systemic Immune-inflammation Index
The primary objective of the study is to determine whether there is a relationship between postoperative SII and erector spinae plane block application.
- Conditions
- Systemic Immune-inflammatory Index, Erector Spinae Plane Block, Breast Conserving Surgery
- Trial name
- NCT07137702
- Testing
- Erector Spinae Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 127 people
- Sponsor
- Taner Abdullah
Overweight and Obesity, Inflammation
Prognostic Value of SII and SIRI in Obesity-Related Metabolic Complications
This observational study aims to evaluate the diagnostic and prognostic value of the systemic immune-inflammatory index (SII) and the systemic inflammation response index (SIRI) in individuals with overweight or obesity.
- Conditions
- Overweight and Obesity, Inflammation, Metabolic Syndrome
- Trial name
- SIMO-PRO (NCT07431593)
- Testing
- Nutritional counselling
- Where
- Croatia
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Rijeka
Multiple Myeloma
CBC-Based Inflammatory Indices in Newly Diagnosed Multiple Myeloma
Multiple myeloma is a type of blood cancer characterized by the abnormal growth of plasma cells in the bone marrow. Increasing evidence indicates that interactions between myeloma cells and the host immune-inflammatory response…
- Trial name
- NCT07823959
- Volunteers
- 60 people
- Sponsor
- Assiut University
Nutrition Assessment, Geriatric Anesthesia
The Effect of Nutritional Status on Postoperative Mortality and Morbidity in the Geriatric Population Undergoing Gastrointestinal Surgery
The purpose of this study was to compare the sensitivity and specificity of the Geriatric Nutritional Risk Index (GNRI), Mini Nutritional Assessment Scale-Short Form (mNA-SF) and Systemic Immune-Inflammatory Index (SII) values…
- Trial name
- NCT07374055
- Testing
- Preoperative Risk Scoring, Postoperative Morbidite and Mortality Monitoring, Delirium Assessment Protocol
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
Inflammatory Response, Perioperative Hypothermia
Effects of Intraoperative Warming Methods on Hematologic Inflammatory Indices in Laparoscopic Cholecystectomy
Perioperative hypothermia is a frequent and preventable complication that may cause adverse outcomes such as increased blood loss, impaired coagulation, and delayed recovery.
- Conditions
- Inflammatory Response, Perioperative Hypothermia, Laparoscopic Cholecystectomy, Surgical Stress Response
- Trial name
- WARM-CHOL (NCT07232251)
- Testing
- Standard Active Warming Blanket, Intravenous Warmer Group, External Warmer Group
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people
- Sponsor
- Ataturk University
Breast Cancer, Postoperative Pain
Preoperative Sleep Quality and Postoperative Outcomes in Breast Surgery
Brief Summary: This prospective, single-center observational study examined the association between preoperative sleep quality and postoperative outcomes in women undergoing elective breast cancer surgery.
- Conditions
- Breast Cancer, Postoperative Pain, Inflammation
- Trial name
- NCT07547774
- Testing
- Preoperative Sleep Quality Assessment (PSQI)
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people
- Sponsor
- Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
Hashimoto Thyroiditis
rT3 and Inflammation in Hashimoto's Thyroiditis
Hashimoto's thyroiditis (HT) is characterized by an enlarged thyroid gland infiltrated with lymphocytes. The incidence of HT is estimated to be 0.3-1.5 cases per 1000 people, with a female/male predominance of 7-10:1.
- Trial name
- NCT07510750
- Where
- Turkey (Türkiye)
- Volunteers
- 179 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Overactive Bladder (OAB)
Predictive Value of Inflammatory Biomarkers for Mirabegron Response in Women With Overactive Bladder
Overactive bladder (OAB) is associated with systemic chronic inflammation. Indices derived from complete blood count (such as neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and systemic…
- Trial name
- NCT07773532
- Testing
- Mirabegron (beta3-adrenoceptor agonist)
- Where
- Turkey (Türkiye)
- Volunteers
- 115 people
- Sponsor
- Bagcilar Training and Research Hospital
Coronary Artery Disease, Systemic Inflammation
MIECC vs Conventional Cardiopulmonary Bypass and Systemic Inflammation in CABG
This prospective observational study evaluates the effects of minimally invasive extracorporeal circulation (MIECC) and conventional cardiopulmonary bypass on systemic inflammatory response in patients undergoing coronary artery…
- Trial name
- MIECC-CABG (NCT07823400)
- Testing
- Minimally Invasive Extracorporeal Circulation, Conventional Cardiopulmonary Bypass
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Lupus Nephritis, Systemic Lupus Erythematosus
SII and SIRI as Prognostic Biomarkers in Lupus Nephritis
This prospective observational study aims to evaluate the prognostic utility of the Systemic Immune-Inflammation Index (SII) and Systemic Inflammation Response Index (SIRI) as novel inflammatory biomarkers for monitoring disease…
- Conditions
- Lupus Nephritis, Systemic Lupus Erythematosus, Kidney Diseases
- Trial name
- NCT07780045
- Volunteers
- 100 people
- Sponsor
- Assiut University