Clinical trials: Systemic Infection
Congenital Heart Disease, Viremia
Congenital Heart Anomaly Risk in Maternal Enteroviral Infection and Diabetes
Beyond EV-B, there are clinical observations to implicate other viruses in birth defects, including CHD. Since the Rubella epidemic of 1960s', however, viruses have received little attention and certainly no comprehensive study…
- Conditions
- Congenital Heart Disease, Viremia, Virus Diseases, Enterovirus
- Trial name
- CHARMED (NCT04769167)
- Testing
- Stool and Blood Specimen Collection, Follow-up Medical Record Review
- Where
- 2 sites in United States
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Bile Duct Stricture, Choledocholithiasis
Prospective Study to Investigate the Frequency of Possible Bacterial Entry Into the Bloodstream (Bacteremia) and Infectious Complications Associated With the Use of the Spyglass Cholangioscopy System During ERCP (Endoscopic Retrograde Cholangiopancreatography).
The aim of this study is to prospectively evaluate the frequency of bacteremia after ERCP/cholangioscopy using the Spyglass Direct Visualization System.
- Trial name
- NCT01414400
- Testing
- Blood draw for culture
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Stanford University
Septic Shock, Nonchemotherapy Drug-induced Neutropenia
Russian Clinical Trial of Mesenchymal Cells in Patients With Septic Shock and Severe Neutropenia
Septic shock remains a significant clinical problem associated with high rates of mortality among neutropenic patient despite antimicrobial therapy and supportive care.
- Conditions
- Septic Shock, Nonchemotherapy Drug-induced Neutropenia, Neutropenia After Chemotherapy in Oncohematological Patients, Neutropenia in Patients With Aplastic Anemia
- Trial name
- NCT01849237
- Testing
- Mesenchymal stromal cells, Standard therapy of septic shock
- Where
- Russia
- Volunteers
- 30 people
- Sponsor
- National Research Center for Hematology, Russia
Systemic Lupus Erythematosus
Ultraviolet Light Therapy for Systemic Lupus Erythematosus
OBJECTIVES: I. Evaluate the mechanisms of ultraviolet A-1 light therapy in patients with systemic lupus erythematosus and normal controls.
- Trial name
- NCT00004375
- Testing
- ultraviolet A-1 light treatment
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- National Center for Research Resources (NCRR)
Catheter-related Bloodstream Infection (CRBSI) Nos
Clinical Trial Comparing Catheter Lock Solutions TaurolockTMHep 100 and Heparin 100 IE/ml.
The purpose of the investigation is to compare two catheter lock solutions (TaurolockTMHep100 and Heparin 100 IE/ml), on the occurence of catheter related blood stream infection, in patients with intestinal failure and a central…
- Trial name
- NCT01948245
- Testing
- TaurolockTMHep100, Heparin 100 IE/ml
- Where
- Denmark
- Volunteers
- 42 people
- Sponsor
- Palle Bekker Jeppesen
Septic Shock, Shock
Balanced Crystalloid vs. Saline in Children With Septic Shock
Fluid resuscitation is the cornerstone of pediatric shock management; current practices of fluid resuscitation in children are not evidence based.
- Trial name
- NCT02835157
- Testing
- Balanced crystalloid solution, 0.9%sodium chloride
- Where
- 4 sites in India
- Volunteers
- 708 people
- Sponsor
- All India Institute of Medical Sciences
Chronic Myeloproliferative Disorders, Leukemia
506U78 in Treating Patients With Hematologic Cancer and Kidney or Liver Impairment
RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. PURPOSE: Phase I trial to study the effectiveness of 506U78 in treating patients who have hematologic cancer…
- Conditions
- Chronic Myeloproliferative Disorders, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm
- Trial name
- NCT00004239
- Testing
- Compound 506U78
- Where
- 3 sites in United States
- Volunteers
- 10 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Neonatal Sepsis
Treatment Outcome With Antibiotic Use and Its Resistance Pattern Among Patient With Neonatal Sepsis
Determine Treatment outcome with antibiotic use and its resistance pattern among neonatal sepsis patients
- Trial name
- NCT05742477
- Testing
- Antibiotic
- Volunteers
- 100 people
- Sponsor
- Assiut University
Sepsis-induced Coagulopathy (SIC)
The Impact of Nafamostat Mesylate on the Prognosis of Patients With Sepsis-Induced Coagulopathy Undergoing Hemofiltration
In sepsis, the body is prone to coagulation system disorders, which may progress to sepsis-induced coagulopathy (SIC). When SIC is persistent and cannot be corrected, it often sequentially develops into disseminated intravascular…
- Trial name
- NCT06994312
- Testing
- Nafamostat Mesylate, sodium citrate
- Volunteers
- 282 people
- Sponsor
- The First Hospital of Jilin University
Sepsis
EARLY-MYO-SEPSIS Registry
The diagnosis and pathophysiology of sepsis-induced cardiac dysfunction remain unknown. This registry is to evaluate characteristics of sepsis patients by multi-modalities imaging, including echocardiography, cardiovascular…
- Trial name
- NCT04513795
- Volunteers
- 300 people
- Sponsor
- RenJi Hospital
Sepsis
Clinical Evaluation of e- Ab Sensor - Based Real-time Diagnosis of Serum Procalcitonin Level
The purpose of this study is to develop a real-time diagnostic technique with e- Ab sensor for serum PCT level measurement will offer a test with lower cost, and increase the applicability of serum Procalcitonin (PCT) level in…
- Trial name
- NCT01388114
- Testing
- Electrosensing Antibody Probe System (e- Ab sensing)
- Where
- Taiwan
- Volunteers
- 200 people
- Sponsor
- National Taiwan University Hospital
The Efficacy and Safety for Super High-flux Dialyzer in Case of Sepsis in ESKD, End Stage Kidney Disease (ESRD)
Comparing Super High-flux and High-flux Dialyzer Performance Among Hemodialysis Patient With Sepsis : a Randomized Control Trial
Comparing the efficacy of superhigh-flux dialyzer with high-flux dialyzer in ESKD patient who have sepsis to improve mortality and sepsis outcome, an open label randomized control trial.
- Conditions
- The Efficacy and Safety for Super High-flux Dialyzer in Case of Sepsis in ESKD, End Stage Kidney Disease (ESRD), Sepsis
- Trial name
- NCT06989892
- Testing
- Super High-flux dialyzer (Elisio 19HDx), High-flux dialyzer (Elisio 19H)
- Where
- Thailand
- Volunteers
- 202 people
- Sponsor
- Navamindradhiraj University
Sepsis, Bacteriemia
Safety and Efficacy of Immages System in Patients Recieving IV Therapy
The study will evaluate the functionality of IMMAGES , an intravenous infusion device system, in patients hospitalized in Bait Balev hospital.
- Conditions
- Sepsis, Bacteriemia, CHF
- Trial name
- IV (NCT02020811)
- Testing
- Sentinel
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- PRo-IV
Cancer Pediatric, Neutropenia
Safety of Acupuncture and Intracutaneous Needles in Pediatric Cancer Patients: a Retrospective Study (ACUSAFE2021)
This study aims to demonstrate the safety of intracutaneous needles in pediatric cancer patients. For this, a two-year retrospective study will be carried out to determine the incidence of adverse effects related to acupuncture…
- Conditions
- Cancer Pediatric, Neutropenia, Thrombocytopenia, Bacteremia
- Trial name
- ACUSAFE2021 (NCT05585463)
- Testing
- acupuncture
- Where
- Spain
- Volunteers
- 460 people
- Sponsor
- Fundació Sant Joan de Déu
Sepsis
The Ohio State University Sepsis Registry
Specific Aim #1: To collect follow-up information about patients with sepsis in the OSUMC MICU who survive to hospital discharge for future retrospective IRB-approved studies.
- Trial name
- NCT00837421
- Where
- United States
- Volunteers
- 230 people
- Sponsor
- Ohio State University
AKI - Acute Kidney Injury
Renal Cell Arrest and Damage Biomarkers in Progression and Outcome of Septic AKI
The aim of the current study is to assess the predictive value of renal cell arrest biomarkers (urinary TIMP2 and IGFBP7), renal damage biomarkers (urinary KIM-1) and microscopic examination of urinary sediment in progression and…
- Trial name
- NCT06064487
- Testing
- renal cell arrest and damage biomarkers assessment
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Alexandria University
Invasive Candidiasis, Candidemia
Micafungin Versus Fluconazole in the Treatment of Invasive Candidiasis and Candidemia
To determine the efficacy and safety of micafungin (FK463) versus fluconazole (Diflucan) in treating patients with invasive candidiasis or candidaemia
- Trial name
- NCT00189709
- Testing
- Micafungin, fluconazole
- Where
- Taiwan
- Volunteers
- 24 people
- Sponsor
- Astellas Pharma Inc
Sepsis
Ubiquinol (Reduced COQ10) for Patients With Sepsis
This study aims to determine if Ubiquinol (reduced form of COQ10) will attenuate mitochondrial injury and decrease inflammatory response in patients suffering from sepsis.
- Trial name
- NCT01948063
- Testing
- Ubiquinol
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Beth Israel Deaconess Medical Center
Lymphoma, Small Intestine Cancer
Combination Chemotherapy With or Without Biological Therapy in Treating Patients With Refractory Solid Tumor or Lymphoma
RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining more than one drug, giving the drugs in different ways, and combining biological therapy with…
- Conditions
- Lymphoma, Small Intestine Cancer, Unspecified Adult Solid Tumor, Protocol Specific
- Trial name
- NCT00005021
- Testing
- filgrastim, carboplatin, paclitaxel
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Fox Chase Cancer Center
Diabetic Ketoacidosis, Heart Disease, Ischemic
Effectiveness of Music Intervention on Anxiety and Physiological Responses in Critical Ill Patient
Music intervention is a non-pharmacological and effective intervention that can alleviate anxiety and agitation in patients undergoing weaning.
- Conditions
- Diabetic Ketoacidosis, Heart Disease, Ischemic, Stroke, GastroIntestinal Bleeding
- Trial name
- NCT04977011
- Testing
- relaxing music
- Where
- Taiwan
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- Min-Sheng General Hospital
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