Clinical trials: Systolic Blood Pressure
Systolic Blood Pressure (20% or Greater Increase)
Factors Predicting Blood Pressure Change With Interscalene Block
The primary aim of this study is to identify potential anthropometric features that predict the relationship between the Interscalene Block procedure and changes in blood pressure
- Trial name
- NCT06394960
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Konya City Hospital
Hypertension
Vitamin D and Blood Pressure
Vitamin D is a natural nutrient in normal daily diet. It can also be made in the skin after exposure to sunlight and is essential for maintaining normal calcium balance.
- Trial name
- NCT00459563
- Testing
- Vitamin D, calcitriol
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Atlanta VA Medical Center
Chronic Kidney Diseases, Hypertension
Remote Ischaemic Conditioning on Blood Pressure Control in Chronic Kidney Disease Patients
Chronic kidney disease (CKD) is one of the leading causes of death and disability in Singapore and worldwide. Hypertension is commonly inadequately controlled in patients with CKD and this is associated with CKD progression and…
- Conditions
- Chronic Kidney Diseases, Hypertension, Cardiovascular Diseases
- Trial name
- ERIC-BP-CKD (NCT03236350)
- Testing
- Active autoRIC® (CRIC Treatment)
- Where
- Singapore
- Volunteers
- 85 people
- Sponsor
- Singapore General Hospital
Resting Heart Rate, Blood Glucose Control
Assessing the Effects of Cool Roofs on Indoor Environments and Health in Colima, Mexico
Ambient air temperatures in Mexico have broken record highs in 2024. Solutions are needed to build heat resilience in communities and adapt to increasing heat from climate change.
- Conditions
- Resting Heart Rate, Blood Glucose Control, Depression, Heat-related Symptoms
- Trial name
- REFLECT (NCT06834893)
- Testing
- Cool roof
- Where
- Mexico
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Aditi Bunker
Hypertension
Efficacy and Safety of Aliskiren in Patients With Mild to Moderate Hypertension During Exercise
This study compared the blunting effect of aliskiren and valsartan monotherapies on exercise-induced rises in systolic blood pressure in patients with mild to moderate essential hypertension.
- Trial name
- NCT00819767
- Testing
- Aliskiren, Valsartan
- Where
- 8 sites in Czechia, Hungary and 2 more
- Volunteers
- 68 people
- Sponsor
- Novartis
Hypertension
Effects of Intensive Systolic Blood Pressure Lowering Treatment in Reducing RIsk of Vascular evenTs (ESPRIT) Study
This trial aims to assess, in patients aged ≥50 years with an average baseline SBP ≥130 mmHg and a previous history of cardiovascular diseases or at high vascular risk, the effects on the incidence of major cardiovascular events…
- Trial name
- ESPRIT (NCT04030234)
- Testing
- Intensive BP treatment group, Standard BP treatment group
- Where
- China
- Volunteers
- 11,255 people
- Sponsor
- China National Center for Cardiovascular Diseases
Placebo Effect, Placebo Mechanisms of Action
Measuring Placebo Effect by Elimination and Investigating Mechanism of Action
We propose to measure the effect of placebo by elimination as well as by a "balanced placebo" design, determine its interaction with active drug, and explore whether placebo exerts part of its effect at the pharmacokinetics level.
- Trial name
- NCT00426010
- Where
- Saudi Arabia
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- King Faisal Specialist Hospital & Research Center
Hypertension
Blood Pressure Lowering of Aliskiren Hydrochlorothiazide (HCTZ) Versus Amlodipine in Stage 2 Hypertension in African Americans
The purpose of the study is to evaluate the efficacy and safety of a fixed dose combination of aliskiren HCTZ versus amlodipine in African American patients with Stage 2 hypertension.
- Trial name
- ATLAAST (NCT00739596)
- Testing
- Aliskiren Hydrochlorothiazide (HCTZ): 8 weeks, Amlodipine: 8 weeks
- Where
- United States
- Volunteers
- 332 people
- Sponsor
- Novartis Pharmaceuticals
Blood Pressure, Endothelial Dysfunction
Novel Time-efficient Inspiratory Muscle Strength Training for Lowering Systolic Blood Pressure
Above-normal systolic blood pressure (SBP), defined as SBP >/= 120 mmHg, is the major modifiable risk factor for cardiovascular disease, stroke, cognitive decline/dementia, and other chronic health problems.
- Conditions
- Blood Pressure, Endothelial Dysfunction, Hypertension
- Trial name
- NCT04848675
- Testing
- Inspiratory muscle strength training, Brisk walking
- Where
- United States
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Boulder
Hypertension
Conventional Versus Automated Measurement of Blood Pressure in the Office (The CAMBO Study)
To determine if the use of automated office blood pressure readings can improve management of systolic hypertension in routine clinical practice.
- Trial name
- CAMBO (NCT00325832)
- Testing
- BpTRU, Conventional mercury sphygmomanometry
- Where
- Canada
- Volunteers
- 750 people
- Sponsor
- Sunnybrook Health Sciences Centre
Food Insecurity Among Children
Evaluation of Demonstrations to End Childhood Hunger - VA
The 2010 Child Nutrition Reauthorization provided funding to test innovative strategies to end childhood hunger and food insecurity.
- Trial name
- EDECHVA (NCT04218747)
- Testing
- VA 365 Demonstration Benefits
- Volunteers
- 4,750 people, healthy volunteers welcome
- Sponsor
- USDA Food and Nutrition Service
Vagus Nerve Stimulation
Vagus Nerve Stimulation Effects on Autonomic Nervous System Activity
Transcutaneous Auricular Vagus nerve stimulation may be successful in cardiac modulation because of the cardiac connections of the vagal nerve.
- Trial name
- NCT06086236
- Testing
- Transcutaneous Auricular Vagus Nerve Stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Bahçeşehir University
Hypertension, Systolic
Olive Polyphenols in Cardiovascular Prevention
The aim of this study is to evaluate whether the use of a commercially available standardized olive extract (Tensiofytol®) in individuals with elevated blood pressure 1.
- Trial name
- NCT04874961
- Testing
- Tensiofytol®
- Where
- Belgium
- Volunteers
- 56 people
- Sponsor
- Nina Hermans
Nontraumatic Intracerebral Hemorrhage, Multiple Localized
Clevidipine (Cleviprex®) Compared With Urapidil (Ebrantil®)
Intracerebral hemorrhage (ICH) is responsible for 10-15% of primary strokes. ICH is a dynamic process with three phases: initial hemorrhage, followed by hematoma expansion and perihematoma edema formation.
- Trial name
- Clevidipine (NCT03300479)
- Testing
- Clevidipine, Urapidil
- Where
- Switzerland
- Sponsor
- University of Zurich
Cirrhosis, Ascites
Application of Bacterial DNA Quantitative Detection in Diagnosis of SBP in Cirrhosis: A Multi Center Diagnostic Experiment
Background and Significance: Spontaneous bacterial peritonitis (SBP) is a common and life-threatening complication in patients with liver cirrhosis, characterized by high incidence and mortality.
- Conditions
- Cirrhosis, Ascites, Bacterial Infections
- Trial name
- NCT06995846
- Testing
- Bacterial DNA Levels in Ascites
- Where
- China
- Volunteers
- 700 people
- Sponsor
- Beijing YouAn Hospital
Postmenopausal Syndrome, Hypertension
Modified Relaxation (MR) Technique for Treating Hypertension in Postmenopausal Women
The purpose of this study is to demonstrate better effectiveness of modified relaxation (MR) technique over no MR for treating hypertension in Thai postmenopausal women.
- Trial name
- NCT01429662
- Testing
- Modified Relaxation (MR), Lifestyle Education (LE)
- Where
- Thailand
- Volunteers
- 429 people
- Sponsor
- Chiang Mai University
Hemodynamic Instability, Anesthesia, General
Hemodynamics During Induction of General Anesthesia With Medium or Low Remifentanil Doses.
In this trial the investigators want to examine if there is any difference in hemodynamic stability during induction when comparing two low and a medium remifentanil dose and keeping propofol induction dose at about 2.0 mg/kg.
- Conditions
- Hemodynamic Instability, Anesthesia, General, Anesthesia, Intravenous
- Trial name
- RH (NCT03861377)
- Testing
- Remifentanil R2, Remifentanil R4, Remifentanil R8
- Where
- Norway
- Volunteers
- 99 people
- Sponsor
- Helse Fonna
Cardiovascular Disease (CVD), Hypertension
Veteran Peer Coaches Optimizing and Advancing Cardiac Health
The purpose of this study is to test if having a Veteran peer health coach will improve blood pressure control among Veterans with high blood pressure and at least one other Cardiovascular disease (CVD) risk factor.
- Conditions
- Cardiovascular Disease (CVD), Hypertension, Hyperlipemia, Obesity
- Trial name
- Vet-COACH (NCT02697422)
- Testing
- Community-based peer health coach intervention
- Where
- United States
- Volunteers
- 264 people
- Sponsor
- VA Office of Research and Development
Diabetes
Achieving Chronic Care equiTy by leVeraging the Telehealth Ecosystem
This study examines the impact of a multi-level intervention aiming to improve telehealth access for low-income patients managing chronic health conditions, such as hypertension and diabetes.
- Trial name
- ACCTiVATE (NCT06598436)
- Testing
- Digital Health Coaching (Patient-Level Intervention), Practice Facilitation (Clinic-Level Intervention)
- Where
- United States
- Volunteers
- 600 people
- Sponsor
- University of California, San Francisco
Hypotension
ED Decision Making Among Hypotensive Patients
The goal of this study is to assess decision making skills of emergency physicians when dealing with hypotensive patients. The hypothesis is that decisions made based on physical exam and vital signs regarding fluid resuscitation…
- Trial name
- NCT02221908
- Testing
- Mespere Venus 1000 CVP System
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Mespere Lifesciences Inc.