Clinical trials: T Cell Subsets
Multiple Sclerosis, MS
Vista Protein Expression of Monocyte and T Cell Subsets in Multiple Sclerosis and Its Clinical Correlation
The aim of this study is to investigate whether VISTA, a newly identified negative immune regulatory protein, differs in monocytes and T cells of patients diagnosed with Multiple Sclerosis (MS) and Clinically Isolated Syndrome…
- Trial name
- NCT06957145
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Koç University
HIV Infections
A Study of Cytotoxic T Lymphocyte (CTL) Therapy in HIV-Infected Patients
To define the safety of cytotoxic T lymphocytes (CTLs) generated from sibling-supplied dendritic cells and lymphocytes and infused into an HIV-infected patient.
- Trial name
- NCT00000824
- Testing
- Lymphocytes, Activated
- Where
- United States
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Hematopoietic Stem Cell Transplantation, Graft vs Host Disease
Repository: Evaluation of Immunoregulatory Cells in Hematopoietic Stem Cell Transplant
This is a repository to store blood and stem cell samples for future research.
- Trial name
- NCT00179075
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Vanderbilt University
Immune Thrombocytopenic Purpura (ITP)
Association of FcγRIIIA Polymorphism and THPO Expression With Response to Eltrombopag in Refractory ITP Patients
Idiopathic thrombocytopenic purpura (ITP) is an autoimmune disease characterized by antibody-mediated platelet destruction. The complex pathogenesis of ITP with multiple challenges to immune system in terms of genetic…
- Trial name
- NCT02877212
- Testing
- Eltrombopag
- Where
- Pakistan
- Volunteers
- 75 people
- Sponsor
- National Institute of Blood and Marrow Transplant (NIBMT), Pakistan
Lymphoma
Correlation Analysis of T-lymphocyte Subsets and Prognosis in Autologous Stem Cell Transplantation (ASCT) for Lymphoma
This is a retrospective, single-center, non-randomized, non-controlled study. This study aims to explore the effect of T-lymphocyte subsets changes in immunologic reconstitution and prognosis in lymphoma patients who were treated…
- Trial name
- NCT03283111
- Testing
- autologous stem cell transplantation
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Peking University
Hematopoietic and Lymphoid Cell Neoplasm, Malignant Solid Neoplasm
Genetically Modified T-Cell Therapy in Treating Patients With Advanced ROR1+ Malignancies
This phase I trial studies the side effects and best dose of genetically modified T-cell therapy in treating patients with receptor tyrosine kinase-like orphan receptor 1 positive (ROR1+) chronic lymphocytic leukemia (CLL)…
- Conditions
- Hematopoietic and Lymphoid Cell Neoplasm, Malignant Solid Neoplasm, Metastatic Lung Non-Small Cell Carcinoma, Metastatic Triple-Negative Breast Carcinoma
- Trial name
- NCT02706392
- Testing
- Laboratory Biomarker Analysis, ROR1 CAR-specific Autologous T-Lymphocytes
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Fred Hutchinson Cancer Center
Immune Thrombocytopenia
Polymorphism and Auto-reactive B and T Cells Subsets in Adult's Immune Thrombocytopenia (ITP)
Aims of the study : 1) To determine whether the presence of the V158 allele of Fc gammaRIIIA gene is associated with a better outcome of Immune Thrombocytopenia (ITP) in adults and especially with a higher response-rate to…
- Trial name
- Poly-ITP (NCT02287649)
- Testing
- blood sample
- Where
- France
- Volunteers
- 45 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Tuberculosis, HIV Infections
Identification of Cytokine Profiles and T Cell Subsets Among Immunosuppressed Patients at Risk of Developing Active Tuberculosis
The purpose of this study is to identify differences in TB specific immune responses among immunosuppressed patients latently infected with TB and patients with active TB.
- Conditions
- Tuberculosis, HIV Infections, Rheumatoid Arthritis
- Trial name
- NCT00285441
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Hvidovre University Hospital