Clinical trials: T2DM
Type 2 Diabetes Mellitus (T2DM), Sarcopenia
HMB Plus Vitamin D to Preserve Muscle in Older Adults Starting Semaglutide
This randomized, double-blind, placebo-controlled trial will evaluate whether daily calcium beta-hydroxy-beta-methylbutyrate (calcium-HMB) plus vitamin D3 preserves muscle mass, physical function, and resting metabolism in adults…
- Conditions
- Type 2 Diabetes Mellitus (T2DM), Sarcopenia, Obesity, Muscle Loss
- Trial name
- PRESERVE-HMB (NCT07760948)
- Testing
- Calcium-HMB Plus Vitamin D3
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Vanderbilt University Medical Center
Type 2 Diabetes Mellitus (T2DM)
Precision Diabetes Education Guided by Diabetes Complication Risk Assessment
This prospective, multicenter interventional study evaluated the implementation of precision diabetes education guided by individualized diabetes complication risk assessment in adults with type 2 diabetes.
- Trial name
- PDE (NCT07793305)
- Testing
- Precision Diabetes Education (PDE)
- Where
- 6 sites in Taiwan
- Volunteers
- 180 people
- Sponsor
- Taiwanese Association of Diabetes Educators
Type 2 Diabetes Mellitus (T2DM), Pain
Effects of Self-Selected Music on Self-Injection Fear, Blood Glucose Testing Fear, and Pain
Fear and pain associated with self-insulin injection and blood glucose self-testing may negatively affect diabetes self-management.
- Conditions
- Type 2 Diabetes Mellitus (T2DM), Pain, Fear of Injections
- Trial name
- NCT06790550
- Testing
- Self-Selected Music Listening
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Dicle University
Supraspinatus Tendinopathy, Type 2 Diabetes Mellitus (T2DM)
Effects of Aerobic Exercise on Shoulder Pain, Disability, and Ultrasonographic Outcomes in Patients With Type 2 Diabetes Mellitus With Supraspinatus Tendinopathy
Type 2 diabetes mellitus (T2DM) is a chronic disease characterized by elevated blood glucose levels over a prolonged period. If left untreated, it can lead to serious and long-term vascular and neurological complications.
- Trial name
- NCT07784543
- Testing
- Conventional Shoulder Rehabilitation, Aerobic Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Pamukkale University
Type 2 Diabetes Mellitus (T2DM), Oxidative Stress
Effect of Rosmarinus Officinalis Extract on Oxidative Stress and Inflammatory Biomarkers in Patients With Type 2 Diabetes (T2DM)
This randomized, placebo-controlled clinical trial evaluates the effects of a methanolic extract of Rosmarinus officinalis (rosemary) in patients with type 2 diabetes mellitus.
- Conditions
- Type 2 Diabetes Mellitus (T2DM), Oxidative Stress, Inflammation Chronic
- Trial name
- T2DM (NCT07541729)
- Testing
- Rosmarinus officinalis extract
- Where
- Mexico
- Volunteers
- 40 people
- Sponsor
- Universidad Autonoma de Zacatecas
Fatty Liver, Nonalcoholic, NAFLD
A Study of HTD1801 in Adults With Nonalcoholic Steatohepatitis (NASH) and Type 2 Diabetes Mellitus (T2DM)
Randomized, double-blind, placebo-controlled, parallel-group study comparing multiple doses of HTD1801 to placebo.
- Conditions
- Fatty Liver, Nonalcoholic, NAFLD, Nonalcoholic Fatty Liver Disease, Nonalcoholic Steatohepatitis
- Trial name
- NCT03656744
- Testing
- HTD1801
- Where
- 17 sites in United States
- Volunteers
- 101 people
- Sponsor
- HighTide Therapeutics (Hong Kong) Limited
Continuous Glucose Monitoring, Quality of Life
Influence of Continuous Glucose Monitoring on Quality of Life in People With Type 2 Diabetes Mellitus
Background: Diabetes Mellitus (DM) is a chronic disease that affects millions of people worldwide. More than 95% of cases are type 2 diabetes mellitus (T2DM).
- Conditions
- Continuous Glucose Monitoring, Quality of Life, Type 2 Diabetes Mellitus (T2DM)
- Trial name
- Glucocavi (NCT06716671)
- Where
- Spain
- Volunteers
- 87 people
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Patient Satisfaction, Continuous Glucose Monitoring
Experience With the Use of Continuous Glucose Monitoring (CGM) Devices in People With Type 2 Diabetes Mellitus
Background: In recent years, diabetes management has evolved with the introduction of continuous glucose monitoring (CGM) devices.
- Conditions
- Patient Satisfaction, Continuous Glucose Monitoring, Type 2 Diabetes Mellitus (T2DM)
- Trial name
- Glucocavi (NCT07019753)
- Where
- Spain
- Volunteers
- 5 people
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Type 2 Diabetes (T2DM)
Clinical Evaluation of Salivary 1,5-Anhydroglucitol in Diabetes
The goal of this observational study is to evaluate the clinical value of salivary 1,5-anhydroglucitol (1,5-AG) and assess a novel noninvasive detection approach in individuals with and without type 2 diabetes.
- Trial name
- NCT07781683
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Shanghai 6th People's Hospital
Type 2 Diabetes Mellitus (T2DM)
A Study to Evaluate the Effect of Fasting Duration and Dulaglutide (LY2189265) Withholding on Gastric Retention in Participants With Type 2 Diabetes Mellitus
The purpose of this study is to evaluate how fasting and stopping the use of Dulaglutide (LY2189265) affect the amount of food and drink that stays in your stomach after a meal.
- Trial name
- GBGT (NCT07313813)
- Testing
- Dulaglutide
- Where
- Singapore
- Volunteers
- 20 people
- Sponsor
- Eli Lilly and Company
Stroke, Hypertension
CEEEC-II: A 12-Week Physical and Cognitive Enrichment Extension Study in Older Stroke Survivors With Multimorbidity
CEEEC-II is a 12-week, community-based, prospective extension study conducted in 32 community health service stations in Kunshan, China.
- Conditions
- Stroke, Hypertension, Type 2 Diabetes Mellitus (T2DM), Multimorbidity
- Trial name
- CEEEC-II (NCT07778771)
- Testing
- Physical Enrichment, Cognitive Enrichment
- Where
- China
- Volunteers
- 365 people
- Sponsor
- Duke Kunshan University
Type 2 Diabetes, Type 2 Diabetes Mellitus (T2DM)
Fitbit and AI Chatbot in Sedentary Primary Care Patients With T2D
The goal of this observational study is to evaluate the feasibility and acceptability of a 12-week intervention utilizing a Fitbit and artificial intelligence (AI)-delivered diabetes self-management education and support (DSMES)…
- Conditions
- Type 2 Diabetes, Type 2 Diabetes Mellitus (T2DM), T2DM (Type 2 Diabetes Mellitus), T2D
- Trial name
- FIT T2D (NCT07005362)
- Testing
- Fitbit and AI Chatbot, Routine Care
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- University of Colorado, Denver
Prediabetes, Type 2 Diabetes (T2DM)
Vitamin D and Type 2 Diabetes - Treat-To-Target
This study tests whether taking a weekly dose of vitamin D, with the dose adjusted to reach a target blood vitamin D level, can help control blood sugar levels in adults at high risk of developing type 2 diabetes (prediabetes).
- Trial name
- D2d-TTT (NCT07448974)
- Testing
- Vitamin D (Cholecalciferol )
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Tufts Medical Center
Type 2 Diabetes Mellitus (T2DM), Insulin Resistance
Validation of the Snouda Metabolic Score for Phenotyping and Guiding Reversal in Type 2 Diabetes
This study tests a new tool called the Snouda Metabolic Score (SMS) that helps doctors identify the specific metabolic problems driving Type 2 Diabetes in each individual patient.
- Conditions
- Type 2 Diabetes Mellitus (T2DM), Insulin Resistance, Metabolic Syndrome
- Trial name
- SMS-VAL (NCT07606872)
- Testing
- Phenotype-Matched Dietary Protocol, Structured Progressive Exercise Protocol, Targeted Nutritional Supplementation
- Where
- United Kingdom
- Volunteers
- 150 people
- Sponsor
- Salah Snouda
Type 2 Diabetes Mellitus (T2DM), Cardiovascular Diseases
Cardioprotective Effects of SGLT2 Inhibitors and GLP-1 Receptor Agonists in Korean Patients With Type 2 Diabetes
This observational study will evaluate the cardiovascular effects of sodium-glucose cotransporter-2 inhibitors (SGLT2 inhibitors) and glucagon-like peptide-1 receptor agonists (GLP-1 receptor agonists) in Korean adults with type…
- Conditions
- Type 2 Diabetes Mellitus (T2DM), Cardiovascular Diseases, Stage B Heart Failure
- Trial name
- NCT07770737
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Dongtan Sacred Heart Hospital
Type 2 Diabetes Mellitus (T2DM)
Diabetes Management Using Continuous Glucose Monitors and Remote Patient Monitoring in Underserved Populations
The goal of this 52 week prospective study is to learn whether a Diabetes Care Management Program using a continuous glucose monitor (CGM) and remotely monitoring (RPM) glucose readings can help improve glucose levels and…
- Trial name
- DCMP (NCT06939413)
- Testing
- Continuous glucose monitor (CGM)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Diabetes Solutions International
Nutrition, Type 2 Diabetes
Pilot of Continuous Glucose Monitor-Augmented Food Is Medicine
This study is designed to test the feasibility and preliminary efficacy of a continuous glucose monitor (CGM)-augmented food is medicine (FIM) intervention for adults with type 2 diabetes and nutrition or food insecurity.
- Conditions
- Nutrition, Type 2 Diabetes, T2DM, T2DM (Type 2 Diabetes Mellitus)
- Trial name
- ALIGN (NCT07148713)
- Testing
- CGM-Augmented FIM, FIM only
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of North Carolina, Chapel Hill
Diabetic Nephropathy Type 2, Type 2 Diabetes Mellitus (T2DM)
Research on Gut Microbiota and Metabolomics in Diabetic Kidney Disease
Diabetic kidney disease (DKD) is characterized by high prevalence, multiple pathogenesis, and lack of effective treatment and management strategies.
- Conditions
- Diabetic Nephropathy Type 2, Type 2 Diabetes Mellitus (T2DM), Chronic Kidney Disease
- Trial name
- NCT06833541
- Where
- China
- Volunteers
- 556 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital of Hunan University of Traditional Chinese Medicine
Type 2 Diabetes (T2DM), Hyperglycemia
CGM-Based Glycemic Analysis After ESI
The goal of this clinical study is to learn how blood glucose levels change after an epidural steroid injection (ESI) with dexamethasone in adults.
- Conditions
- Type 2 Diabetes (T2DM), Hyperglycemia, Radicular Pain, Spinal Stenosis
- Trial name
- CGMSteroid (NCT07280780)
- Testing
- Epidural Steroid Injection, Continuous Glucose Monitoring
- Where
- South Korea
- Volunteers
- 36 people
- Sponsor
- Korea University Anam Hospital
Type 2 Diabetes Mellitus (T2DM), Obesity (Disorder)
Digital Dietary Intervention for Patients Receiving GLP-1 Receptor Agonist Therapy
The goal of this clinical trial is to learn whether adding the NutriSteppe digital dietary intervention to routine medical care improves metabolic health in adults aged 21 to 65 years with type 2 diabetes mellitus, obesity, or…
- Conditions
- Type 2 Diabetes Mellitus (T2DM), Obesity (Disorder), Overweight, Metabolic Syndrome
- Trial name
- NutriSteppe (NCT07728669)
- Testing
- NutriSteppe Digital Dietary Intervention
- Where
- Kazakhstan
- Volunteers
- 120 people
- Sponsor
- Kazakh Academy of Nutrition