Clinical trials: T2DM (Type 2 Diabetes Mellitus)
Supraspinatus Tendinopathy, Type 2 Diabetes Mellitus (T2DM)
Effects of Aerobic Exercise on Shoulder Pain, Disability, and Ultrasonographic Outcomes in Patients With Type 2 Diabetes Mellitus With Supraspinatus Tendinopathy
Type 2 diabetes mellitus (T2DM) is a chronic disease characterized by elevated blood glucose levels over a prolonged period. If left untreated, it can lead to serious and long-term vascular and neurological complications.
- Trial name
- NCT07784543
- Testing
- Conventional Shoulder Rehabilitation, Aerobic Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Pamukkale University
Type 2 Diabetes (T2DM), Hepatocellular Carcinoma (HCC)
HCC Risk and Monitoring in Patients With Type 2 Diabetes
Liver cancer is a significant malignancy in Taiwan. With the widespread implementation of antiviral therapies, hepatitis B and C-related liver cancer has gradually declined; however, metabolic dysfunction-associated liver cancer…
- Trial name
- GAAD-DM (NCT07675187)
- Testing
- GAAD score
- Where
- Taiwan
- Volunteers
- 2,400 people
- Sponsor
- National Taiwan University Hospital
T2DM (Type 2 Diabetes Mellitus), Fatty Liver
Measurement of Alanine Aminotransaminase (ALT) Following Initiation of Antidiabetic Agents in Patients With Type 2 Diabetes in a Real-world Clinical Setting: a Retrospective Cohort Study
The primary objective of this study is to investigate the change in Alanine Aminotransaminase (ALT) in patients with Type 2 Diabetes Mellitus (T2DM) initiating Sodium Glucose Cotransporter 2 (SGLT2) inhibitors, liraglutide, or…
- Conditions
- T2DM (Type 2 Diabetes Mellitus), Fatty Liver, NAFLD
- Trial name
- ALT (NCT03233178)
- Testing
- Non-interventional
- Where
- Canada
- Volunteers
- 4,000 people
- Sponsor
- LMC Diabetes & Endocrinology Ltd.
Diabetes Mellitus, Type 2
Insulin Glargine Injection Treatment in Place of Thiazolidinedione (TZD), Sulfonylurea, or Metformin in Triple Agent Therapy for Type 2 Diabetes Mellitus (T2DM) Adult Subjects With Unsatisfactory Control
The purpose of this study is to compare the change in hemoglobin A1c (HbA1c) from baseline to Week 12 between the 3 treatment arms.
- Trial name
- NCT00283049
- Testing
- Insulin Glargine, Insulin Glulisine
- Where
- United States
- Volunteers
- 390 people
- Sponsor
- Sanofi
Type 2 Diabetes Mellitus, Hypertension
A Multi-site, Individually Randomized, Controlled Translation Trial of Integrated and Comprehensive Care Strategies to Reduce Cardiovascular Disease (CVD) Risk Among 1,120 Type 2 Diabetes Mellitus(T2DM) Patients in South Asia
Background: Cardiovascular diseases (CVD) are currently the leading cause of death globally and Asian Indians will account for between 40-60% of the global CVD burden within the next 10-15 years.
- Conditions
- Type 2 Diabetes Mellitus, Hypertension, Dyslipidaemia
- Trial name
- CARRS (NCT01212328)
- Testing
- Care Coordinator + Decision Support Software, Usual care
- Where
- 10 sites in India, Pakistan
- Volunteers
- 1,120 people
- Sponsor
- Public Health Foundation of India
Diabetes Mellitus, Type 2
A Study Based on Data From German Registries That Looks at Characteristics of People Who Take the Medicine Empagliflozin for Type 2 Diabetes
Description of the real-life treatment of adult patients with type-2 diabetes mellitus (T2DM) receiving Empagliflozin, comparing the characteristics of patients starting Empagliflozin in three time intervals
- Trial name
- EDCOS (NCT04098575)
- Testing
- Empagliflozin
- Where
- Germany
- Volunteers
- 9,571 people
- Sponsor
- Boehringer Ingelheim
Carpal Tunnel Syndrome (CTS), Type 2 Diabetes Mellitus (T2DM)
The Effect of Local Corticosteroid Injection in Carpal Tunnel Syndrome Patients With Type 2 Diabetes
Our study was planned as a prospective observational study aiming to compare the post-intervention recovery process between patients with carpal tunnel syndrome (CTS) and diabetes mellitus and patients with idiopathic carpal…
- Trial name
- NCT07433257
- Testing
- 1 mL 40 mg [40 mg/mL] triamcinolone acetonide + 1 mL 2% lidocaine hydrochloride
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Haydarpasa Numune Training and Research Hospital
Type 2 Diabetes Mellitus (T2DM)
Phase I Study to Evaluate the Pharmacokinetics and Safety After Co-administration of L03RD1 and L03RD2 or Administration of L03TD1 in Healthy Volunteers
This is a randomized, open, single-dose, crossover-design, phase I study to evaluate the pharmacokinetics and safety after co-administration of L03RD1 and L03RD2 or administration of L03TD1 in healthy volunteers.
- Trial name
- NCT07533539
- Testing
- L03RD1, L03RD2, L03TD1
- Where
- South Korea
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Celltrion
Type 2 Diabetes (T2DM), Diabetic Nephropathies
A Multicenter Randomized Double-Blind Trial of Chrocare CDSS for Integrated Management of Type 2 Diabetes
This is a multicenter, randomized, double-blind, parallel-group clinical study for adults with type 2 diabetes and early diabetic kidney or retinal complications.
- Conditions
- Type 2 Diabetes (T2DM), Diabetic Nephropathies, Diabetic Retinopathy (DR)
- Trial name
- Chrocare-DM (NCT07833228)
- Testing
- AI large language model-based clinical decision support system, Standard diabetes integrated management formulated by endocrinologists
- Where
- China
- Volunteers
- 1,200 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
T2DM, Type 2 Diabetes Mellitus
A Phase 3 Study to Evaluate the Efficacy of XW003 Compared With Dulaglutide in Participants With T2DM
The aim of the study is to compare the efficacy and safety of two XW003 doses versus dulaglutide as add-on therapy to metformin in participants with type 2 diabetes mellitus (T2DM)
- Trial name
- NCT05680129
- Testing
- Ecnoglutide high dosage, Ecnoglutide low dosage, Dulaglutide
- Where
- China
- Volunteers
- 623 people
- Sponsor
- Hangzhou Sciwind Biosciences Co., Ltd.
Obese Diabetics, Obese Non Diabetic
Comparative Study of Different Weekly GLP-1 Receptor Agonists Among Diabetic and Non-Diabetic Patients: Clinical Trial
titel : Comparative Study of Different Weekly GLP-1 Receptor Agonists Among Diabetic and Non-Diabetic Patients: Clinical Trial Abstract : Background: This study that highlights the different effects of most used three GLP-RA…
- Trial name
- NCT07820111
- Testing
- Dulaglutide 1.5 MG/ML, Semaglutide 2 mg/1.5 ml (1.34 mg/ml), prefilled pen-injector for subcutaneous injection solution, Tirzepatide is administered as part of routine clinical care for obesity management, according to standard prescribing practices. Dosing and treatment duration are determined by the treating physician
- Where
- Saudi Arabia
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Type 2 Diabetes Mellitus
Study to Assess the Effect of 24 Weeks of Treatment With Vildagliptin in Patients With Type 2 Diabetes
The study will demonstrate the effect of 24 weeks of treatment with vildagliptin compared to placebo on insulin sensitivity in patients with type 2 diabetes mellitus (T2DM) treated with metformin, assessed as glucose Rd (rate of…
- Trial name
- NCT01356381
- Testing
- Vildagliptin
- Where
- United Kingdom
- Volunteers
- 43 people
- Sponsor
- Novartis Pharmaceuticals
Diabetes Mellitus, Type 2
Glucose Homeostasis and Incretin Effect T2DM in the Youth- a Study of the Malaysian Population
Early onset type 2 diabetes mellitus among adolescents/youth (YT2DM) is a rising phenomenon. The pathophysiology has been studied primarily on non-Asian populations while literature on incretin effect is scarce.
- Trial name
- NCT02845557
- Testing
- OGTT and IVGTT tests
- Where
- Malaysia
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- RCSI & UCD Malaysia Campus
Diabetes Mellitus, Type 2
To Evaluate Clinical Outcome and Injection Compliance of Scilin
This is a prospective, multi-center, open-label, non-interventional, 12-week study in people with type 2 diabetes mellitus who are treated with recombinant human insulin-SciLin N, SciLin R and SciLin M30 (alone or in combination)…
- Trial name
- SEAS (NCT01588639)
- Testing
- Insulin (Scilin N, BAY81-9924), Insulin (Scilin R _BAY81-9924, Insulin(Scilin M30_BAY81-9924)
- Where
- China
- Volunteers
- 2,683 people
- Sponsor
- Bayer
Obesity
Effectiveness and Safety of Tirzepatide Among Participants With Obesity With or Without Type 2 Diabetes Mellitus (T2DM)
This is a prospective, multicenter, real-world study conducted in Bangladesh to assess the effectiveness and safety of Tirzepatide compared to structured lifestyle interventions, including dietary modifications and exercise, in…
- Trial name
- NCT07099742
- Testing
- Tirzepatide, Life Style Modification
- Where
- 3 sites in Bangladesh
- Volunteers
- 364 people
- Sponsor
- Dr. Md. Alimur Reza
Diabetes
Mechanisms of Glucose Lowering Effects of Sitagliptin and Metformin Alone and in Combination in Patients With T2DM
In patients with type 2 diabetes with inadequate glycemic control on diet and exercise after 6 weeks of treatment: Objective: To assess the effects of co-administration of sitagliptin and metformin compared to placebo on hepatic…
- Trial name
- NCT00820573
- Testing
- Sitagliptin, Metformin, Sitagliptin + Metformin
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Type 2 Diabetes
To Evaluate Safety and Tolerability After Multiple Oral Doses of AZD1656 in Type 2 Diabetes Patients on Top of Metformin
The purpose of this study is to assess safety and tolerablility of AZD1656 after multiple repeated oral doses in patients with type 2 diabetes on top of metformin.
- Trial name
- NCT00774553
- Testing
- AZD1656
- Where
- 2 sites in United States, India
- Volunteers
- 70 people
- Sponsor
- AstraZeneca
Sleep Apnea, Obstructive, Type 2 Diabetes Mellitus
Effect of Oral Appliance Therapy on Glucose Levels in Patients With T2DM and OSA: A Pilot Trial
This study will evaluate the impact on blood glucose of the use of an oral appliance to treat obstructive sleep apnea (OSA) in individuals with Type 2 diabetes.
- Trial name
- NCT03167684
- Testing
- Oral appliance therapy
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Type 2 Diabetes Mellitus
Impact Evaluation of a Mobile Health App to Improve Self-control and Health Outcomes of Patients With Type 2 Diabetes Mellitus (T2DM): Pilot Study "NOVAME"
The objective of this project is to evaluate the effectiveness and cost effectiveness of a health app (NOVAME) designed to improve the self-control of patients with T2DM and their health outcomes.
- Trial name
- NOVAME (NCT03663738)
- Testing
- mobile app NOVAME
- Where
- Spain
- Volunteers
- 199 people
- Sponsor
- Servicio Canario de Salud
Type 2 Diabetes Mellitus
CAPTIVATE India - A Study to Assess the Prevalence of Cardiovascular Disease (CVD) in Individuals With Type 2 Diabetes Mellitus (T2DM) in India
This is a cross-sectional study assessing the prevalence of Cardiovascular Disease and describing cardio-renal risk factors among individuals with Type 2 Diabetes Mellitus in India based on medical records.
- Trial name
- NCT07121114
- Testing
- No treatment given
- Where
- India
- Volunteers
- 1,500 people
- Sponsor
- Novo Nordisk A/S