Clinical trials: T2DM (Type 2 Diabetes Mellitus)
Type 2 Diabetes Mellitus (T2DM)
The Digital Diabetes Patient Reminder (DIPAR) Tool For Adults With Type 2 Diabetes
Digital health tools may present an opportunity to address these challenges by enhancing care delivery, improving patient engagement, and facilitating better disease management for chronic diseases such as type 2 diabetes…
- Trial name
- DIPAR RCT (NCT07257822)
- Testing
- Digital Diabetes Patient Reminder Tool, Standard of Care treatment and follow-up
- Where
- 2 sites in Belgium
- Volunteers
- 200 people
- Sponsor
- KU Leuven
Type 2 Diabetes Mellitus (T2DM)
CGM for Insulin-Treated T2DM During Post-Discharge Transition
The transition from inpatient care to the home setting is a critical phase for glycemic management, often associated with decreased adherence and deterioration of glycemic control.
- Trial name
- TRANSIT-CGM (NCT07414277)
- Testing
- RT-CGM, SMBG
- Where
- 4 sites in China
- Volunteers
- 160 people
- Sponsor
- Shanghai 6th People's Hospital
Type 2 Diabetes Mellitus (T2DM), Coronary Artery Disease (CAD)
Multiple Electrode Aggregometry & Clopidogrel Resistance
Antiplatelet therapy with aspirin-clopidogrel reduces the risk of cardiovascular episodes after percutaneous coronary intervention (PCI) in patients with acute coronary syndromes.
- Conditions
- Type 2 Diabetes Mellitus (T2DM), Coronary Artery Disease (CAD), Myocardial Infraction
- Trial name
- NCT01991093
- Where
- 3 sites in Greece
- Volunteers
- 280 people
- Sponsor
- Elpen Pharmaceutical Co. Inc.
T2DM (Type 2 Diabetes Mellitus), Hypertension
Virtual Diabetes Group Visits Across Health Systems
The purpose of this project is to evaluate the effectiveness of a virtual diabetes group visits on patients with type 2 diabetes mellitus (T2DM).
- Conditions
- T2DM (Type 2 Diabetes Mellitus), Hypertension, Heart Disease Chronic, Stroke
- Trial name
- VIDA (NCT06094491)
- Testing
- Virtual Group Visit
- Where
- 2 sites in United States
- Volunteers
- 720 people
- Sponsor
- University of Chicago
Sarcopenia, Obesity Type 2 Diabetes Mellitus
Sarcopenia Risk in Obese T2DM Patients
This study aims to measure handgrip strength, walking speed, and the risk of muscle wasting in obese patients who have had diabetes for 5 years or longer, and to evaluate the relationship of these measures with factors that may…
- Trial name
- NCT07905274
- Testing
- physical examination
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Bandırma Onyedi Eylül University
Type 2 Diabetes Mellitus (T2DM)
A Study to Evaluate the Effect of Fasting Duration and Dulaglutide (LY2189265) Withholding on Gastric Retention in Participants With Type 2 Diabetes Mellitus
The purpose of this study is to evaluate how fasting and stopping the use of Dulaglutide (LY2189265) affect the amount of food and drink that stays in your stomach after a meal.
- Trial name
- GBGT (NCT07313813)
- Testing
- Dulaglutide
- Where
- Singapore
- Volunteers
- 20 people
- Sponsor
- Eli Lilly and Company
Type 2 Diabetes Mellitus
A Study to Investigate the Effect of MEDI0382 on Hepatic Glycogen Metabolism in Overweight and Obese Subjects With Type 2 Diabetes Mellitus.
A phase 2 study in two parts (A \& B) designed to evaluate the effect of MEDI0382 on Hepatic Glycogen Metabolism in subjects with Type 2 Diabetes Mellitus (T2DM).
- Trial name
- NCT03555994
- Testing
- MEDI0382, Liraglutide
- Where
- 3 sites in Netherlands, Sweden and 1 more
- Volunteers
- 51 people
- Sponsor
- MedImmune LLC
T2DM (Type 2 Diabetes Mellitus), MASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease
Duodenal pulsENDO for Suboptimally Controlled Type II Diabetes Mellitus and Steatotic Liver Disease
This study is designed to evaluate the efficacy, safety, and mechanisms of pulsENDO procedure in patients with T2DM and its effect on MASLD.
- Conditions
- T2DM (Type 2 Diabetes Mellitus), MASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease, Metabolic Syndrome (MetS)
- Trial name
- DRESS-1 (NCT07390422)
- Testing
- pulsENDO treatment
- Where
- Hong Kong
- Volunteers
- 40 people
- Sponsor
- Chinese University of Hong Kong
Type 1 Diabetes Mellitus, Type 2 Diabetes Mellitus (T2DM)
Feasibility of a Tailored Online Self-compassion Intervention
The goal of this clinical trial is to examine the feasibility and acceptability of an online programme that is based on Compassionate Mind Training (CMT) over four-weeks.
- Trial name
- NCT07051005
- Testing
- Feasibility RCT of a tailored online self-compassion intervention
- Where
- 2 sites in United Kingdom
- Volunteers
- 50 people
- Sponsor
- Canterbury Christ Church University
Diabetes Mellitus Type 2
Hypoglycemia- and Weight-related Quality of Life in Patients With Diabetes Mellitus Type 2 on Sulfonylurea Derivatives.
1. A prospective, non-interventional study, 125 patients with Diabetes Mellitus Type2 will be enrolled, who, while on metformin, have a sub-optimal glycemic control and who thus will receive additional treatment with a…
- Trial name
- NCT01244646
- Where
- 22 sites in Netherlands
- Volunteers
- 48 people
- Sponsor
- AstraZeneca
Type II Diabetes Mellitus
A Clinical Study to Evaluate the Safety, Tolerability, PK, PD, and Efficacy of KBP-089 in Patients With T2DM
KeyBioscience is developing KBP-089, a dual activator of both the amylin and calcitonin receptors, for the treatment of type II diabetes mellitus, using a subcutaneous injectable mode of administration.
- Trial name
- NCT03907202
- Where
- Germany
- Volunteers
- 25 people
- Sponsor
- KeyBioscience AG
Type 2 Diabetes Mellitus
A 12-week Study To Evaluate PF-06291874 Once a Day in Adults With T2DM Inadequately Controlled On Metformin
The purpose of this study is to determine whether PF-06291874 is effective in the treatment T2DM
- Trial name
- NCT02554877
- Testing
- PF-06291874
- Where
- 38 sites in United States, Canada
- Volunteers
- 206 people
- Sponsor
- Pfizer
Diabetes Mellitus, Type 2
A Study of LY3549492 in Participants With Type 2 Diabetes Mellitus (T2DM)
The main purpose of this study is to evaluate the safety and tolerability of LY3549492 in participants with T2DM. Blood tests will be done to check how much LY3549492 gets into the bloodstream and how the body handles LY3549492.
- Trial name
- NCT05327595
- Testing
- LY3549492, Atorvastatin, Midazolam
- Where
- Germany
- Volunteers
- 80 people
- Sponsor
- Eli Lilly and Company
Type 2 Diabetes Mellitus (T2DM)
Precision Lifestyle Interventions Guided by Continuous Glucose Monitoring: Impact on Glycemic Outcomes in Type 2 Diabetes Mellitus
This study is an interventional research. Through scientific evaluation, it explores the effect of precise lifestyle intervention based on CGM data on the control of chronic type 2 diabetes mellitus.
- Trial name
- NCT06960512
- Testing
- Precision Lifestyle Intervention (PLI) group
- Volunteers
- 200 people
- Sponsor
- He Eye Hospital
Elevated Blood Pressure, Hypertension
WeArable teChnology daTa driVen digitAl healTh cOachINg (ACTIVATION)- A Mixed-methods Study
Public health priorities have shifted towards disease prevention, emphasising health promotion and lifestyle interventions to reduce disease burden.
- Conditions
- Elevated Blood Pressure, Hypertension, Overweight/Obesity, Type 2 Diabetes Mellitus (T2DM)
- Trial name
- NCT06752772
- Testing
- Smart watch, Dashboard with nudging system, Digital Health Coach (DHC)
- Where
- Singapore
- Volunteers
- 1,700 people
- Sponsor
- Alexandra Hospital
Type 2 Diabetes Mellitus (T2DM)
Intervention Effects of Optimized Carbohydrate Diet in Patients With Type 2 Diabetes
This study is a multi-center, randomized, crossover investigator-initiated trial conducted at Shanghai Sixth People's Hospital and other centers.
- Trial name
- NCT06936657
- Testing
- optimized carbohydrate diet, conventional diabetes diet
- Volunteers
- 150 people
- Sponsor
- Shanghai 6th People's Hospital
Type 2 Diabetes
To Evaluate the Response to Glucagon During Hypoglycemia
The purpose of this study is to evaluate the response to Glucagon versus the spontaneous hormonal response to low blood sugar levels in T2DM Patients treated with AZD1656 and Metformin
- Trial name
- NCT00817271
- Testing
- AZD1656, Glucagon
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- AstraZeneca
Type 2 Diabetes Mellitus (T2DM), Self-management
Effects of a Researcher-Designed Diabetes Self-Management App on Self-Management Obstacles, Self-Efficacy, and Physiological Indicators in Type 2 Diabetes
This study aims to evaluate the effectiveness of a self-developed diabetes self-management mobile application on disease self-management outcomes among individuals with type 2 diabetes.
- Trial name
- Application (NCT07794384)
- Testing
- Researcher-Designed Diabetes Self-Management Application
- Volunteers
- 80 people
- Sponsor
- Fu Jen Catholic University Hospital
Diabetes
Duodenal Exclusion for the Treatment of T2DM
Evaluation of duodenal exclusion procedure for the treatment of T2DM
- Trial name
- NCT00456352
- Testing
- duodenal exclusion
- Where
- Brazil
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Medtronic - MITG
Type II Diabetes Mellitus, Efficacy, Self
Real World Safety & Efficacy Experience of Empagliflozin With or Without Metformin in T2DM Patients - EASE Study
Study Objective To evaluate the safety and tolerability of Empagliflozin with or without metformin in patients with Type II Diabetes Mellitus in the Pakistani population.
- Conditions
- Type II Diabetes Mellitus, Efficacy, Self, Safety Issues
- Trial name
- EASE (NCT05164263)
- Testing
- Empagliflozin
- Where
- 6 sites in Afghanistan, Kenya and 3 more
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Getz Pharma