Clinical trials: TBI-Traumatic Brain Injury
Brain Concussion
Effects of Neuromuscular Training on EEG Adaptations in Young Athletes
The purpose of the current project is to determine the effects of augmented neuromuscular training on brain neuroplasticity. Specifically we aim to evaluate the potential of augmented NMT (aNMT) to alter brain neural performance…
- Trial name
- NCT03913975
- Testing
- Neuromuscular training
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Traumatic Brain Injury, Post-traumatic Epilepsy
Transforming Research and Clinical Knowledge in Traumatic Brain Injury Epileptogenesis Project (TRACK-TBI EPI)
The overarching goal of this study is to improve understanding of the long-range natural history of TBI and post-traumatic epilepsy (PTE) by extending follow-up of a previously enrolled cohort (TRACK-TBI) beyond the first 12…
- Trial name
- NCT05823766
- Testing
- In-Person Outcome Assessment, 3T Magnetic Resonance Imaging (MRI), Clinical Visit
- Where
- 9 sites in United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Brain Concussion, Post-Concussion Syndrome
Exercise in Postconcussion Symptoms and Posttraumatic Headache
The goal of this clinical trial is to compare two models of delivery of guided exercise in patients with exercise intolerance after mild head injury.
- Conditions
- Brain Concussion, Post-Concussion Syndrome, Post-Traumatic Headache, Craniocerebral Trauma
- Trial name
- NCT06015451
- Testing
- Sub-symptom threshold exercise
- Where
- Norway
- Volunteers
- 100 people
- Sponsor
- St. Olavs Hospital
Traumatic Brain Injury (TBI) Patients, Severe Traumatic Brain Injury
SeeMe: Using Automated Facial Tracking to Detect Voluntary Behavior in Brain Injury
Objective: This prospective interventional study introduces "SeeMe," an automated, high-resolution computer vision platform designed to objectively quantify microscopic, auditory command-evoked movements in patients with…
- Trial name
- NCT07560631
- Testing
- SeeMe Multimodal Auditory Command Protocol
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Stony Brook University
Brain Injuries
Manual-Based Vocational Rehabilitation Program for Patients With Acquired Brain Injury
An acquired brain injury (ABI) is a complex injury often followed by a broad range of cognitive, physical, emotional, and behavioral disabilities.
- Trial name
- NCT03086031
- Testing
- Program -based vocational rehabilitation intervention, Conventional vocational rehabilitation (controls)
- Volunteers
- 84 people
- Sponsor
- Brain Injury Center BOMI, Roskilde, Denmark
Brain Injuries, Traumatic
Assignment of the Verbal Component Score and Addition of Pupil Reaction to the Glasgow Coma Scale
In this study, it is aimed to determine the prognostic value of GCS-P and the GCS-P score, which is formed by assigning a verbal score, in patients with traumatic brain injury, where all parameters can be evaluated.
- Trial name
- NCT05767502
- Testing
- GCS-Pupil score
- Where
- Turkey (Türkiye)
- Volunteers
- 199 people
- Sponsor
- Uludag University
Traumatic Brain Injury
S-100B as Pre-Head CT Scan Screening Test After Mild Traumatic Brain Injury
The purpose of the study is to determine if a specific blood protein, S-100B, can help predict who will have a traumatic abnormality on head CT scan after a concussion.
- Trial name
- NCT00717301
- Where
- 6 sites in United States
- Volunteers
- 1,252 people
- Sponsor
- University of Rochester
Mild Traumatic Brain Injury
Olfactory Function in Patients With Acute Mild Traumatic Brain Injury
In this project the investigators aim to evaluate olfactory and non-olfactory function in patients within the first 24h following a mild traumatic brain injury (acute mTBI) and compare their results to a group of age and sex…
- Trial name
- NCT02977728
- Testing
- Olfactory Evaluation
- Volunteers
- 42 people
- Sponsor
- Hôpital de Viege
Traumatic Brain Injury
Developing Process-Specific Verbal Memory Interventions for Veterans With Tramatic Brain Injury (TBI)
Blast-related and blunt traumatic brain injury is a key priority area of Rehabilitation Research \& Development (RR\&D) and represents a critically important public health problem facing the Veteran population.
- Trial name
- DPSVM (NCT02310633)
- Testing
- Memory Strategy Training, Errorless Learning, Retrieval Practice
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Brain Injuries, Disorders of Consciousness
Erigo®Pro Coma Outcome Study - Study on the Effectiveness of a Robotic Tilt Table Device for Recovery of Consciousness
Patients with acquired brain injury (ABI) often suffer from severe disorders of consciousness (DOC), such as coma, unresponsive wakefulness syndrome (UWS), or minimally conscious state (MCS).
- Trial name
- EriCOS (NCT02639481)
- Testing
- Standard physiotherapy, Erigo®Pro group without FES, Erigo®Pro group with FES
- Where
- 2 sites in Germany
- Volunteers
- 47 people
- Sponsor
- Ludwig-Maximilians - University of Munich
Injury, Traumatic Brain Injury
Pennsylvania Abusive Head Trauma Prevention Program
This project is designed to evaluate a statewide, hospital-based parent education program to prevent abusive head trauma (AHT) in Pennsylvania, and investigate the additional effectiveness and cost-effectiveness of "booster"…
- Conditions
- Injury, Traumatic Brain Injury, Child Abuse
- Trial name
- NCT00727116
- Testing
- PA Abusive Head Trauma Prevention Program: State-wide, PA Abusive Head Trauma Prevention Program Booster: Central PA
- Volunteers
- 949,609 people
- Sponsor
- Centers for Disease Control and Prevention
Traumatic Brain Injury
Transcranial Doppler on Admission of Patients With Mild to Moderate Traumatic Brain Injury
Patients with mild to moderate traumatic brain injury (TBI) are at risk for secondary neurological deterioration. Their outcome within the first week after injury could be predicted by clinical signs, brain CT scan and…
- Trial name
- TCD (NCT01291706)
- Testing
- Transcranial Doppler
- Where
- 21 sites in France
- Volunteers
- 369 people
- Sponsor
- University Hospital, Grenoble
Post-Traumatic Headache, PTSD
Art Therapy QEEG Study for Service Members with a Traumatic Brain Injury and Posttraumatic Stress Symptoms
Service members and/or recently separated veterans with post traumatic stress symptoms and mild traumatic brain injury may participate in 8 sessions including 2 sessions including interviews and questionnaires as well as 6…
- Conditions
- Post-Traumatic Headache, PTSD, TBI, TBI (Traumatic Brain Injury)
- Trial name
- ArtTherapy (NCT04776304)
- Testing
- Art Therapy
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Walter Reed National Military Medical Center
Mild to Moderate Traumatic Brain Injury, Cognitive Rehabilitation
Goal-oriented Telehealth Rehabilitation of Executive Functioning for Veterans With Chronic TBI
Provision of interventions that address cognitive and emotional problems faced by Veterans with history of TBI pursuing community reintegration is an important concern for VA.
- Conditions
- Mild to Moderate Traumatic Brain Injury, Cognitive Rehabilitation, Veteran
- Trial name
- GOALS TH (NCT07190365)
- Testing
- GOALS TH, EDU TH
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- VA Office of Research and Development
Traumatic Brain Injury
TRACK-TBI Longitudinal Biomarker Study
The overarching goal of this study is to improve understanding of the long-range natural history of TBI by extending follow-up of a previously enrolled cohort (TRACK-TBI) beyond the first 12 months after injury.
- Trial name
- TRACK-BIO (NCT05201833)
- Testing
- Telephone Outcome Assessment, In-Person Outcome Assessment, 3T Magnetic Resonance Imaging (MRI)
- Where
- 11 sites in United States
- Volunteers
- 300 people
- Sponsor
- University of Pennsylvania
Brain Concussion
Tele-Rehabilitation to Improve Mild Traumatic Brain Injury Recovery and Reduce Subsequent Injury Risk
The goal of this clinical trial is to examine the feasibility, utility, and efficacy of a smartphone-based assessment battery and remotely administered virtual Neuromuscular/Dual-Task (vNDT) intervention among healthy U.S.
- Trial name
- NCT05594225
- Testing
- Virtual Neuromuscular/Dual-Task Training
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- University of Colorado, Denver
Traumatic Brain Injury
Executive Function Training Intervention for Chronic Traumatic Brain Injury
Traumatic Brain Injury (TBI) is a prevalent disorder developed by military personnel. While some individuals recover function within months after injury, others continue to suffer from cognitive problems months to years later and…
- Trial name
- NCT03704116
- Testing
- Expedition
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- The University of Texas at Dallas
Disorder of Consciousness, Minimally Conscious State
Temporal Interference Stimulation for Disorders of Consciousness
This study aims to investigate whether a new non-invasive brain stimulation technique, called temporal interference stimulation, can influence brain activity and potentially improve signs of consciousness in patients with severe…
- Conditions
- Disorder of Consciousness, Minimally Conscious State, Vegetative State, Unresponsive Wakefulness Syndrome
- Trial name
- NCT07874178
- Testing
- Temporal Interference
- Volunteers
- 4 people
- Sponsor
- Centre Hospitalier Universitaire de Liege
Head Injury, Traumatic Brain Injury
Selective CT for Anticoagulated Head Injured Patients
The goal is to derive and a clinical decision rule for safe exclusion of traumatic brain injury without neuroimaging in head-injured ED patients who take anticoagulant medications. The objectives are to: 1.
- Conditions
- Head Injury, Traumatic Brain Injury, Intracranial Hemorrhage, Traumatic, Blunt Head Injury
- Trial name
- Can-SCAHn (NCT05364749)
- Where
- 7 sites in Canada
- Volunteers
- 4,000 people
- Sponsor
- Dr. Kerstin de Wit
Sex Trafficking, Mental Disorder
Survivors of Sex Trafficking: Occupation-Based Interventions for Executive Functioning
Persons traumatized through sex trafficking can demonstrate similar neurobehavioral and executive function (EF) deficits as persons with cortical injuries.
- Trial name
- NCT03611998
- Testing
- Occupation-based programming
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Louisiana State University Health Sciences Center in New Orleans