Clinical trials: THA, open to volunteers
Syphilis Infection, Gonorrhea
The Efficacy of Doxycycline Post Exposure Prophylaxis for Preventing STIs Among MSM in Bangkok, Thailand.
The objective of this research is to evaluate the efficacy and safety of doxycycline in MSM for preventing sexually transmitted infections (gonorrhea, chlamydia, and syphilis) in Thailand Participation in this study will last…
- Conditions
- Syphilis Infection, Gonorrhea, Chlamydia
- Trial name
- ThaiDoxyPEP (NCT07397403)
- Testing
- Doxycycline (200mg/day)
- Where
- Thailand
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Bangrak STIs Center
Total Hip Arthroplasty (THA)
MFinity BE Pre-market Trial
The primary objective of this trial is to determine the implant survival at 1 year of follow up in a population of patients undergoing primary Total Hip Replacement with MFinity Collared Femoral stem and to test its…
- Trial name
- NCT07616895
- Testing
- Mfinity collared stem
- Volunteers
- 95 people
- Sponsor
- Medacta International SA
THA
Bikini vs Longitudinal Incision in Direct Anterior Approach (DAA) Total Hip Arthroplasty (THA)
The study team is conducting this study to see if there is a difference between the wound healing and participant satisfaction rates between two incision types used during a THA done via the DAA technique.
- Trial name
- NCT06831045
- Testing
- Bikini Incision, Longitudinal Incision
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- University of Miami
Postoperative Recovery in Children
Thai Version of the Pediatric Quality of Recovery Score (PedSQoR): Translation and Psychometric Validation Study
Postoperative recovery in children is a complex, multidimensional process that differs substantially from recovery in adults, encompassing physical comfort, emotional well-being, behavioral changes, and psychosocial functioning.
- Trial name
- Thai-PedsQoR (NCT07378501)
- Where
- Thailand
- Volunteers
- 130 people
- Sponsor
- Mahidol University
University Students, Psychological Well Being
Development of the Online Mindfulness-based Intervention (Mind Space Application) for Thai-university Students: Phase II
Development of the online mindfulness-based intervention (MFU-mindful Application for Thai university students: Phase II Objectives: Phase I: (October 2025 to September 2026) 1.
- Conditions
- University Students, Psychological Well Being, Mindfulness
- Trial name
- NCT07346612
- Testing
- mind space intervention
- Where
- Thailand
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Mae Fah Luang University
HIV Prevention
Evaluation of PrEP-30: a Demonstration Project of Pre-exposure Prophylaxis for MSM and Other High-risk Group Clients at the Thai Red Cross Anonymous Clinic
PrEP-30 is a demonstration project to assess the feasibility of providing oral PrEP to MSM and other individuals at-risk for HIV in Bangkok, Thailand as a service that is funded entirely through user fees.
- Trial name
- PrEP-30 (NCT02437981)
- Testing
- PrEP
- Where
- Thailand
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- Thai Red Cross AIDS Research Centre
Restless Legs Syndrome
Prevalence and Characteristics of Restless Leg Syndrome in Thai Patients With Parkinson's Disease
Parkinson's disease (PD) is a progressive neurodegenerative disorder characterized by pathologic intraneuronal alpha-synuclein-positive Lewy bodies and neuronal cell loss.
- Trial name
- NCT06684782
- Testing
- Screening for symptoms of restless leg syndrome
- Where
- 2 sites in Thailand
- Volunteers
- 310 people, healthy volunteers welcome
- Sponsor
- Siriraj Hospital
Total Hip Arthroplasty, Computer-Assisted Surgery
Pre-Op THA Modelling
Replacing diseased hip joints with prosthetic implants in a procedure called total hip arthroplasty (THA) is associated with high rates of patient satisfaction, pain relief, and functional improvement when the implant is…
- Trial name
- NCT05221554
- Testing
- Imageless computer-navigated THA surgery, Standard of care THA surgery, CT-based Computer-navigated THA surgery
- Where
- Canada
- Volunteers
- 180 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
ALS (Amyotrophic Lateral Sclerosis)
Amyotrophic Lateral Sclerosis Registry in Thailand
This is a prospective, observational, multicenter registry designed to collect comprehensive clinical, genetic, and outcome data from patients diagnosed with amyotrophic lateral sclerosis (ALS) across Thailand.
- Trial name
- Thai ALS Regis (NCT07175935)
- Where
- Thailand
- Volunteers
- 100 people
- Sponsor
- Chulalongkorn University
Postoperative Pain, Total Hip Arthroplasty (THA)
PENG Block With or Without PPD Block for Postoperative Analgesia After Total Hip Arthroplasty
This single-center, prospective, randomized controlled clinical trial aims to compare the postoperative analgesic efficacy of PENG block with or without posterior pericapsular deep gluteal block in adult patients undergoing…
- Trial name
- NCT07502248
- Testing
- PENG Block, Deep posterior gluteal compartment block
- Volunteers
- 40 people
- Sponsor
- Kirsehir Ahi Evran Universitesi
Total Hip Arthroplasty (THA), Kinesiophobia (Fear of Movement)
Effect of Cognitive Behavioral Therapy on Kinesiophobia and Functional Outcomes After Total Hip Arthroplasty.
The goal of this clinical trial study is to evaluate the effectiveness of cognitive behavioral therapy in reducing kinesiophobia and improving Clinical outcomes in postoperative patients following total hip arthroplasty The main…
- Trial name
- NCT07427758
- Testing
- Cognitive-behavioral therapy, Exercise
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Cairo University
Total Hip Arthroplasty (THA), Hemiarthroplasty
Post-Market Clinical Follow-Up (PMCF) Study Evaluating the Safety and Efficacy of Tıpmed™ Primary Hip Prosthesis System
This is a multicenter, prospective, observational, post-market clinical follow-up (PMCF) study designed to evaluate the safety and clinical performance of the Tipmed™ Primary Hip Prosthesis System in adult subjects undergoing…
- Conditions
- Total Hip Arthroplasty (THA), Hemiarthroplasty, Osteoarthritis (OA) of the Hip, Femoral Neck Fractures
- Trial name
- NCT07651735
- Testing
- Tipmed™ Primary Hip Prosthesis System
- Where
- 4 sites in Turkey (Türkiye)
- Volunteers
- 101 people
- Sponsor
- TIPMED Medical Device Manufacturing Ltd. Co.
Post Operative Pain, Total Hip Arthroplasty
Methadone in THA for Post-op Pain and Opioid Reduction
This randomized, double-blind controlled trial investigates whether intraoperative intravenous methadone (0.15 mg/kg based on ideal body weight) reduces acute postoperative pain and opioid consumption in patients undergoing…
- Trial name
- NCT07227064
- Testing
- Methadone
- Where
- United States
- Volunteers
- 162 people
- Sponsor
- Medical University of South Carolina
Knee Osteoarthritis, Hip Osteoarthritis
Daycase Hip and Knee Arthroplasty in Møre and Romsdal Trial
The DART Study is a prospective, multicentre observational cohort study evaluating day-case pathways for patients undergoing primary total hip arthroplasty, total knee arthroplasty, or unicompartmental knee arthroplasty at three…
- Conditions
- Knee Osteoarthritis, Hip Osteoarthritis, Osteonecrosis, Osteoarthritis
- Trial name
- DART (NCT07834034)
- Testing
- Total Hip Arthroplasty, Total Knee Arthroplasty, Unicondylar knee artrhoplasty
- Where
- 3 sites in Norway
- Volunteers
- 300 people
- Sponsor
- Helse Møre og Romsdal HF
Total Hip Arthroplasty (THA)
Early Rehabilitation After Total Hip Arthroplasty
This study aims to investigate the effects of an early postoperative rehabilitation program combined with neuromuscular electrical stimulation (NMES) and telerehabilitation on functional recovery in patients undergoing total hip…
- Trial name
- NCT07550647
- Testing
- Early Postoperative Physiotherapy, Neuromuscular Electrical Stimulation (NMES), Telerehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Muğla Sıtkı Koçman University
Knee Phenotype Changes After THA, Coronal Plane Alignment of the Knee
Change of Knee Phenotype After Total Hip Arthroplasty
this study evaluates changes in knee phenotype after total hip arthroplasty using radiographic assessment of coronal alignment in a prospective cohort of patients
- Trial name
- THA-KP (NCT07597538)
- Where
- Egypt
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Nader Ahmed Sayed Abdelhamed
Cholangiocarcinoma, Liver Fluke-Related Cholangiocarcinoma
Evaluating a Community-Based Behaviour Change Communication Model to Prevent Cholangiocarcinoma in Khon Kaen, Thailand
Liver cancer, specifically cholangiocarcinoma (CCA), is very common in different areas in Thailand. Many factors make this cancer more common, such as liver fluke infection, older age, eating raw fish, family history of cancer…
- Conditions
- Cholangiocarcinoma, Liver Fluke-Related Cholangiocarcinoma, Opisthorchiasis
- Trial name
- eCHEC (NCT05321992)
- Testing
- eCHEC program
- Where
- Thailand
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- McMaster University
HIV/AIDS
Efficacy, Acceptability and Safety of Event-driven HIV PrEP Using TAF/FTC in MSM in Thailand and France.
The purpose of this study is to evaluate the efficacy, acceptability, and safety of a simplified event-driven pre-exposure prophylaxis of HIV based on oral TAF/FTC in HIV-uninfected cisgender men who have sex with men (MSM).
- Trial name
- SimpPrEP (NCT05813964)
- Testing
- TDF/FTC 300mg/200mg fixed-dose combination tablets, TAF/FTC 25mg/200mg fixed-dose combination tablets
- Where
- 6 sites in France, Thailand
- Volunteers
- 524 people, healthy volunteers welcome
- Sponsor
- ANRS, Emerging Infectious Diseases
Total Hip Arthroplasty (THA), Impaction
Automated V Manual Impactor Study
This study investigates the use of an automated impactor device in total hip arthroplasty versus manual malleting method and the physiological strain on the surgeon.
- Conditions
- Total Hip Arthroplasty (THA), Impaction, Physiological Strain
- Trial name
- NCT06903767
- Testing
- Automated Impaction (HAMMR), Manual Malleting
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Rothman Institute Orthopaedics