Clinical trials: TIA
Acute Ischaemic Stroke, Transient Ischaemic Attack
[SOCRATES -Acute Stroke Or Transient IsChaemic Attack TReated With Aspirin or Ticagrelor and Patient OutcomES]
The primary objective of the study is to compare the effect of 90-day treatment with ticagrelor (180 mg [two 90 mg tablets] loading dose on Day 1 followed by 90 mg twice daily maintenance dose for the remainder of the study) vs…
- Trial name
- SOCRATES (NCT01994720)
- Testing
- ticagrelor, Acetylsalicylic acid (ASA)
- Where
- 521 sites in United States, Argentina and 31 more
- Volunteers
- 13,307 people
- Sponsor
- AstraZeneca
Stroke, TIA
Platelet Expression of FcγRIIa and Arterial Hemodynamics to Predict Recurrent Stroke in Intracranial Atherosclerosis
An observational study to determine if individuals with increased platelet FcyRIIa will have a higher risk of ischemic events.
- Conditions
- Stroke, TIA, Ischemic Stroke, Ischemic
- Trial name
- FCG (NCT05518305)
- Testing
- Medical Imaging
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Apnea, Sleep Apnea Syndromes
Oropharyngeal Exercises and Post-Stroke Obstructive Sleep Apnea
This study evaluates the feasibility and effectiveness of an oropharyngeal exercise (O-PE) regimen in treating post-stroke obstructive sleep apnea, as an alternative therapy to continuous positive airway pressure (CPAP).
- Conditions
- Apnea, Sleep Apnea Syndromes, Sleep Apnea, Obstructive, Stroke
- Trial name
- NCT04212260
- Testing
- Oropharyngeal exercises
- Where
- Canada
- Volunteers
- 33 people
- Sponsor
- Sunnybrook Health Sciences Centre
Stroke
Stroke Self-Management: Effect on Function and Stroke Specific Quality of Life
The experience of a stroke event may result in a disruption to the survivor's daily life. Patients with stroke have reported fears of permanent disability and major concerns over their ability to recover and be productive and…
- Trial name
- NCT01507688
- Testing
- Stroke Self-Management
- Where
- 2 sites in United States
- Volunteers
- 258 people
- Sponsor
- VA Office of Research and Development
Brain Ischemia, Transient Ischemic Attack
ESPRIT: European/Australasian Stroke Prevention in Reversible Ischaemia Trial
The objective of ESPRIT was to compare the efficacy and safety of mild anticoagulation or a combination treatment of aspirin and dipyridamole with the efficacy and safety of treatment with aspirin alone after cerebral ischemia of…
- Conditions
- Brain Ischemia, Transient Ischemic Attack, Arteriosclerosis
- Trial name
- NCT00161070
- Testing
- anticoagulation, aspirin and dipyridamole, aspirin alone
- Where
- Netherlands
- Volunteers
- 4,500 people
- Sponsor
- UMC Utrecht
Abdominal Obesity, Cardiovascular Diseases
Grain Exercise Trial - Whole Grain Versus no Grain With or Without Physiotherapy-promoted Exercise for Waist Loss
The main purpose of this 2-year lifestyle experiment for waist loss is twofold: 1. to compare whole grains and no grains as part of a healthy diet, 2.
- Conditions
- Abdominal Obesity, Cardiovascular Diseases, Diabetes Type 2, Hypertension
- Trial name
- GET (NCT01208558)
- Testing
- Diet A, Diet B, Physiotherapy
- Where
- Sweden
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Lund University
Acute Coronary Syndrome, Stroke
Florbetaben for Imaging of Vascular Amyloid
The Primary Objective is to determine if a new nuclear tracer (named 18F-Florbetaben) used with nuclear imaging (PET imaging) can detect inflamed plaque in patients with recent ACS or stroke/TIA.
- Conditions
- Acute Coronary Syndrome, Stroke, Transient Ischemic Attack, Atherosclerosis of Artery
- Trial name
- FERMATA (NCT06091319)
- Testing
- [18F]-Florbetaben PET and CT imaging
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ottawa Heart Institute Research Corporation
Abdominal Aortic Aneurysm
Screening of Abdominal Aortic Aneurysms Among Male Patients With TIA Symptoms
The purpose of this study is to investigate the prevalence of abdominal aortic aneurysms (AAA) among male patients with transient ischemic attack (TIA) symptoms.
- Trial name
- NCT01850732
- Testing
- Ultrasound of aorta
- Where
- Finland
- Sponsor
- North Karelia Central Hospital
Carotid Artery Disease, Carotid Artery Stenosis
Neurological Outcome With Carotid Artery Stenting
The purpose of this study is to determine how well patients undergoing carotid artery angioplasty and/or stent-supported angioplasty for the treatment of carotid artery stenosis will perform on a battery of tests to assess brain…
- Conditions
- Carotid Artery Disease, Carotid Artery Stenosis, Stroke, Transient Ischemic Attack
- Trial name
- CAS (NCT00597974)
- Testing
- Angioplasty, Stent, Neurological and neuropsychological evaluations
- Where
- United States
- Volunteers
- 108 people
- Sponsor
- Columbia University
Patent Foramen Ovale
PFx Closure System in Subjects With Cryptogenic Stroke,Transient Ischemic Attack,Migraine or Decompression Illness(PFO)
The primary objective of this study is to demonstrate the safety and performance of the PFx Closure System when utilized for patients with PFOs suffering from cryptogenic stroke, transient ischemic attack, migraine or…
- Trial name
- NCT00335296
- Testing
- PFx catheter
- Where
- 4 sites in Belgium, France and 1 more
- Volunteers
- 100 people
- Sponsor
- Cierra
Ischemic Stroke, Transient Ischemic Attack
AcoArt VI / Vertebral Artery Ostium Stenosis in China
The purpose of this study is to determine whether DEB is not inferior to common bare metal stent using under in long-term vessel patency and inhibiting restenosis in Vertebral Artery Ostium Stenosis
- Trial name
- NCT03910166
- Testing
- drug-coated balloon catheter（Orchid, Acotec）, Intracranial artery stent system（APOLLO）
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Acotec Scientific Co., Ltd
Stroke (CVA) or TIA, Hemiparesis
Mirror Therapy on Motor Recovery and Pain of Hemiparetic Arm
evaluate the effect of mirror therapy on motor recovery and pain of hemiparetic arm post stroke
- Trial name
- NCT07358169
- Testing
- technique, Control
- Where
- Egypt
- Volunteers
- 72 people
- Sponsor
- Mansoura University
Stroke, Transient Ischemic Attack
VITATOPS: A Study of VITAmins TO Prevent Stroke
The VITATOPS study is a multi-center, randomized, double blind, placebo-controlled secondary stroke prevention trial to determine whether the addition of vitamin supplements (B12 500 ug, B6 25 mg, Folate 2 mg) to best…
- Trial name
- NCT00097669
- Where
- 111 sites in United States, Australia and 18 more
- Volunteers
- 8,164 people
- Sponsor
- VITATOPS
Stroke, Transient Ischaemic Attack
Diagnosis by Comprehensive Cardiovascular Imaging for Stroke and TIA
Stroke affects over 125,000 people each year in the UK and leaves at least 50% disabled. After a first stroke, there is a significant risk of recurrence (around 5-10% over the first year).
- Trial name
- DCCIST (NCT03618069)
- Testing
- CCI scanning (CTA, cardiac CT), and MRI scanning
- Volunteers
- 100 people
- Sponsor
- NHS Greater Glasgow and Clyde
Transient Ischemic Attack (TIA)
Canadian TIA Score Versus ABCD2 Score in Risk Stratification of Transient Ischemic Attack (TIA)
This study aims to evaluate the superiority of a clinical score (Canadian TIA score) compared to the currently more widely used score in clinical practice (ABCD2 score) in stratifying the risk of stroke or carotid…
- Trial name
- NCT06718075
- Where
- Italy
- Volunteers
- 800 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Stroke, Ischemic Attack, Transient
Performing a Low-dose, Whole-body Angiography as the First Element of an Imaging Assessment Following Stroke / TIA
The main objective of this study is to compare two post-stroke/TIA (transient ischemic attack) imaging strategies in terms of the number of clinically important (i.e.
- Trial name
- VASCU (NCT02662751)
- Testing
- Routine Imaging Assessment, LDWBA first (CT scan)
- Where
- 2 sites in France
- Volunteers
- 260 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Ischemic Stroke, Transient Ischemic Attack
VISSIT Intracranial Stent Study for Ischemic Therapy
The main objective of this study is to prospectively evaluate the safety, probable benefit, and effectiveness of the PHAROS Vitesse Neurovascular Stent System in a multicenter, randomized clinical trial.
- Trial name
- VISSIT (NCT00816166)
- Testing
- Pharos Vitesse Neurovascular Stent System (Stent implantation) + Medical therapy (Aspirin and Clopidogrel), Aspirin and Clopidogrel (Medical therapy)
- Volunteers
- 125 people
- Sponsor
- Codman & Shurtleff
Stroke, Brain Ischemia
A Novel Rural Integrated Care and Early Prevention Model for Older Adults at High Risk of or Living With Stroke in China
This cluster randomized controlled trial aims to evaluate the effectiveness of a novel telemedicine-enabled integrated care model led by rural doctors in reducing cardiovascular and cerebrovascular events among elderly adults…
- Conditions
- Stroke, Brain Ischemia, Cerebral Hemorrhage, Transient Ischemic Attack
- Trial name
- NCT07628283
- Testing
- Enhanced Usual Stroke Care, Digital Health Platform-Supported Integrated Stroke Management
- Where
- 2 sites in China
- Volunteers
- 2,510 people
- Sponsor
- Jiangsu Province (Suqian) Hospital
Stroke, Ischemic Attack, Transient
Home Blood Pressure Monitoring Trial
Design: Community based randomised trial with follow up after 12 months Participants: 360 patients admitted with stroke or TIA within the past 9 months will be recruited from the wards or outpatients and randomly allocated into…
- Trial name
- NCT00514800
- Testing
- Intervention - a validated home BP monitor and support from the specialist nurse, Control - usual care (BP monitoring by their practice)
- Where
- 3 sites in United Kingdom
- Volunteers
- 360 people
- Sponsor
- St George's, University of London
Apathy, Stroke Sequelae
Accelerated rTMS for Post-Stroke Apathy
This pilot study will investigate the safety, feasibility, tolerability, and preliminary efficacy of accelerated high-dose repetitive transcranial magnetic stimulation (rTMS) targeting the medial prefrontal cortex (mPFC) to…
- Conditions
- Apathy, Stroke Sequelae, Stroke (CVA) or TIA, Stroke/Brain Attack
- Trial name
- NCT05878457
- Testing
- MagVenture MagPro Transcranial Magnetic Stimulation (TMS) System
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Medical University of South Carolina